2,240 research outputs found
The 25 October 2010 Mentawai tsunami earthquake (M_w 7.8) and the tsunami hazard presented by shallow megathrust ruptures
The 25 October 2010 Mentawai, Indonesia earthquake (M_w 7.8) ruptured the shallow portion of the subduction zone seaward of the Mentawai islands, off-shore of Sumatra, generating 3 to 9 m tsunami run-up along southwestern coasts of the Pagai Islands that took at least 431 lives. Analyses of teleseismic P, SH and Rayleigh waves for finite-fault source rupture characteristics indicate âŒ90 s rupture duration with a low rupture velocity of âŒ1.5 km/s on the 10° dipping megathrust, with total slip of 2â4 m over an âŒ100 km long source region. The seismic moment-scaled energy release is 1.4 Ă 10^(â6), lower than 2.4 Ă 10^(â6) found for the 17 July 2006 Java tsunami earthquake (M_w 7.8). The Mentawai event ruptured up-dip of the slip region of the 12 September 2007 Kepulauan earthquake (M_w 7.9), and together with the 4 January 1907 (M 7.6) tsunami earthquake located seaward of Simeulue Island to the northwest along the arc, demonstrates the significant tsunami generation potential for shallow megathrust ruptures in regions up-dip of great underthrusting events in Indonesia and elsewhere
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The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death.
Reactive oxygen species (ROS) play a key role in development of heart failure but, at a cellular level, their effects range from cytoprotection to induction of cell death. Understanding how this is regulated is crucial to develop novel strategies to ameliorate only the detrimental effects. Here, we revisited the fundamental hypothesis that the level of ROS per se is a key factor in the cellular response by applying different concentrations of H2O2 to cardiomyocytes. High concentrations rapidly reduced intracellular ATP and inhibited protein synthesis. This was associated with activation of AMPK which phosphorylated and inhibited Raptor, a crucial component of mTOR complex-1 that regulates protein synthesis. Inhibition of protein synthesis by high concentrations of H2O2 prevents synthesis of immediate early gene products required for downstream gene expression, and such mRNAs (many encoding proteins required to deal with oxidant stress) were only induced by lower concentrations. Lower concentrations of H2O2 promoted mTOR phosphorylation, associated with differential recruitment of some mRNAs to the polysomes for translation. Some of the upregulated genes induced by low H2O2 levels are cytoprotective. We identified p21Cip1/WAF1 as one such protein, and preventing its upregulation enhanced the rate of cardiomyocyte apoptosis. The data support the concept of a "redox rheostat" in which different degrees of ROS influence cell energetics and intracellular signalling pathways to regulate mRNA and protein expression. This sliding scale determines cell fate, modulating survival vs death
Finite Temperature Behavior of the Quantum Hall Effect in Bilayer Electron Systems
An effective field theoretic description of bilayer electron systems
stabilized by Coulomb repulsion in a single wide quantum well is examined using
renormalization group techniques. The system is found to undergo a crossover
from a low temperature strongly correlated quantum Hall state to a high
temperature compressible state. This picture is used to account for the recent
experimental observation of an anomalous transition in bilayer electron systems
(T. S. Lay, {\em et al.} Phys. Rev. B {\bf 50}, 17725 (1994)). An estimate for
the crossover temperature is provided, and it is shown that its dependence on
electron density is in reasonable agreement with i the experiment.Comment: Corrected typos, and changed content, 5 pages and 2 figures, accepted
in Phys. Rev.
Brst Cohomology and Invariants of 4D Gravity in Ashtekar Variables
We discuss the BRST cohomologies of the invariants associated with the
description of classical and quantum gravity in four dimensions, using the
Ashtekar variables. These invariants are constructed from several BRST
cohomology sequences. They provide a systematic and clear characterization of
non-local observables in general relativity with unbroken diffeomorphism
invariance, and could yield further differential invariants for four-manifolds.
The theory includes fluctuations of the vierbein fields, but there exits a
non-trivial phase which can be expressed in terms of Witten's topological
quantum field theory. In this phase, the descent sequences are degenerate, and
the corresponding classical solutions can be identified with the conformally
self-dual sector of Einstein manifolds. The full theory includes fluctuations
which bring the system out of this sector while preserving diffeomorphism
invariance.Comment: 15 page
Quantum universal detectors
We address the problem of estimating the expectation value of an
arbitrary operator O via a universal measuring apparatus that is independent of
O, and for which the expectation values for different operators are obtained by
changing only the data-processing. The ``universal detector'' performs a joint
measurement on the system and on a suitably prepared ancilla. We characterize
such universal detectors, and show how they can be obtained either via Bell
measurements or via local measurements and classical communication between
system and ancilla.Comment: 4 pages, no figure
Magnetic Anisotropy in Quantum Hall Ferromagnets
We show that the sign of magnetic anisotropy energy in quantum Hall
ferromagnets is determined by a competition between electrostatic and exchange
energies. Easy-axis ferromagnets tend to occur when Landau levels whose states
have similar spatial profiles cross. We report measurements of integer QHE
evolution with magnetic-field tilt. Reentrant behavior observed for the QHE at high tilt angles is attributed to easy-axis anisotropy. This
interpretation is supported by a detailed calculation of the magnetic
anisotropy energy.Comment: 12 pages, 3 figures, submitted to Phys. Rev. Let
Could One Find Petroleum Using Neutrino Oscillations in Matter?
In neutrino physics, it is now widely believed that neutrino oscillations are
influenced by the presence of matter, modifying the energy spectrum produced by
a neutrino beam traversing the Earth. Here, we will discuss the reverse
problem, i.e. what could be learned about the Earth's interior from a single
neutrino baseline energy spectrum, especially about the Earth's mantle. We will
use a statistical analysis with a low-energy neutrino beam under very
optimistic assumptions. At the end, we will note that it is hard to find
petroleum with such a method, though it is not too far away from technical
feasibility.Comment: 6 pages, 4 figures, EPL LaTeX. Final version to be published in
Europhys. Let
Anisotropic Transport of Quantum Hall Meron-Pair Excitations
Double-layer quantum Hall systems at total filling factor can
exhibit a commensurate-incommensurate phase transition driven by a magnetic
field oriented parallel to the layers. Within the commensurate
phase, the lowest charge excitations are believed to be linearly-confined Meron
pairs, which are energetically favored to align with . In order
to investigate this interesting object, we propose a gated double-layer Hall
bar experiment in which can be rotated with respect to the
direction of a constriction. We demonstrate the strong angle-dependent
transport due to the anisotropic nature of linearly-confined Meron pairs and
discuss how it would be manifested in experiment.Comment: 4 pages, RevTex, 3 postscript figure
Searching for coronal radio emission from protostars using Very-Long-Baseline Interferometry
In order to directly study the role of magnetic fields in the immediate
vicinity of protostars, we use Very-Long-Baseline Interferometry (VLBI), aiming
at the detection of non-thermal centimetric radio emission. This is technically
the only possibility to study coronal emission at sub-AU resolution. We
performed VLBI observations of the four nearby protostars HL Tau, LDN 1551
IRS5, EC 95, and YLW 15 in order to look for compact non-thermal centimetric
radio emission. For maximum sensitivity, we used the High Sensitivity Array
(HSA) where possible, involving the Very Long Baseline Array (VLBA), the phased
Very Large Array (VLA), as well as the Arecibo, Green Bank, and Effelsberg
radio telescopes. While all four protostars were detected in VLA-only data,
only one source (YLW 15 VLA 2) was detected in the VLBI data. The possibility
of non-detections due to free-free absorption, possibly depending on source
geometry, is considered. For YLW 15 VLA 2, the prospects for an accurate orbit
determination appear to be good.Comment: 8 pages, 4 figures, accepted for publication in A&
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