Agricultural Extension Agents’ Awareness Of Ict Potentials And Training Needs On Usage For Improved Extension Service Deliv- Ery In Selected Southwest States Of Nigeria

The   study   examined   the   agricultural   extension   workers’ awareness   of   ICT   potentials   and   training needs on ICT usage for improved extension service delivery in selected southwest states of Nigeria. A multistage sampling technique was used to select a total of 132 extension workers’ from Lagos and Ogun States Agricultural Development   Programmes   (LADA  and OGADEP).   A  validated  and  reliable questionnaire was used to obtain primary data on socioeconomic characteristics of the respondents, their awareness of ICT potentials and training needs on ICT usage for improved extension services delivery. Data collected were analysed using frequency counts, percentages and chi-square statistics. Result of the analysis showed that most of the respondents were the Village Extension Agents (78.8 %,), and about 34.1% of them were within the age range of 41 and 45years. About 72.7% the exten- sion agents had first degree (HND/BSc) as the least educational qualification and about 57.6% of them have spent between 11 and 20 years in the extension services. The result also showed that all the extension agents were familiar with the Global System Mobile communication (GSM), 58.3% with the computer and 38.6% of them with the internet. About 43.2% of the extension workers were moderately aware of the ICT potentials for improved extension service delivery based on their mean awareness score of 8.5 (53.1%). The chi-square test of the relationship between the extension workers’ socioeco- nomic characteristics (education: χ² = 45.5,  df = 12; professional rank: χ² = 38.7,  df = 9; working ex- perience χ² = 65.2, df = 12) and level of awareness of the ICT potentials showed a significant relation- ship at p < 0.05. Similarly, a significant relationship was observed between the extension agents’ level of awareness of ICT potentials and their needs for training on usage for improved extension service delivery (χ² = 71.3, df = 18) at p < 0.05. In the light of this, it was concluded that the extension workers had moderate level awareness of ICT potentials for improved extension services and were in need of training on usage in their extension activities. It was recommended that education on ICT potentials and   training on  usage for improved  extension service delivery   should   be promoted and intensified among the extension workers.      &nbsp

chemical constituents anti nociceptive and anti inflammatory activities of essential oil of phyllanthus muellerianus

The aim of the present study was to characterize the chemical composition and to evaluate the anti-inflammatory and anti-nociceptive properties of the essential oil from the leaves of Phyllanthus muellerianus (Kuntze) Exell. The essential oil was hydrodistilled and characterized by gas chromatography-flame ionization detection and gas chromatography coupled with mass spectrometry analyses. The anti-inflammatory activity was evaluated on carrageenan-induced rat paw edema while the anti-nociceptive test was based on hot plate analysis. The hydrodistillation afforded 0.09% (dry weight basis) of pale yellow oil. Thirty-eight compounds representing 94.8% were identified in the oil. The major components of the oil were hexahydrofarnesyl acetone (11.6%), isocaryophyllene (9.8%), and limonene (9.4%). The oils of P. muellerianus displayed anti-nociceptive effect at a rate independent of reaction time and dose (P < 0.001). The rate of inhibition increased exponentially as the dose increases with optimum activity at..

Small Ruminant Farmers' Perception of Climate Change in Moro Local Government Area, Kwara State, Nigeria

This study examined the small ruminant farmers’ perception of climate change in Moro Local Government Area (LGA) of Kwara State, Nigeria. About 120 small ruminant farmers were selected for the study. Analyticall tools such as descriptive (frequency count, percentage, mean score) and inferential [Pearson product moment correlation (PPMC)] statistics were used to analyse the data. The result revealed that about 57.5% of the respondents were male, average age of 38.3years, income of N56633.33, and household size of about 5 persons. The average number of goat and sheep was 10 and 5 respectively. About 52% of the respondents utilized extensive system of rearing and 60.8% had access to extension services. About 77.5% of the respondents indicated Ministry of Agriculture as their main source of information on small ruminant production. The result revealed that planting of trees/erecting cover to serve as shades to reduce heat stress (90.8%) was the most frequently used adaptation strategies to climate change. About 59.2% of the respondents have high level/status of use of adaptation strategies. The highest ranked perception statement was increase in temperature (4.48), while disease outbreak and high mortality (2.78) ranked highest as factor affecting small ruminant production. It is therefore recommended that there should be provision of information on the adaptation strategies as climate change is now a reality that is not going away and provision of veterinary services to reduce disease outbreak

Knowledge, practice and acceptability of HPV vaccine by mothers of adolescent girls in Ilorin, Nigeria

Background: Human Papilloma Virus (HPV) is a sexually transmitted cause of carcinoma of the cervix. An important determinant of the success of a primary preventive strategy like HPV vaccination is the knowledge and willingness of parents to vaccinate adolescents before sexual debut. Materials and methods of study: A cross sectional descriptive survey of mothers of girls in 8 secondary schools in Ilorin was carried out from February to April 2015. Schools were selected using multi staged sampling. Descriptive and inferential statistics were performed with Chi Square and ANOVA. Results: There were 470 questionnaires returned for analysis out of 600, giving a response rate of 78.3%. One hundred and sixty-one (34.3%) knew HPV to be sexually transmitted infection and 40.4% knew it was the cause of cervical cancer. While 35.1% were aware of HPV vaccine, only 1.9% had ever vaccinated their children.Less than half (44.9%) were willing to vaccinate their children. Women with good knowledge of HPV and cervical cancer were more willing to vaccinate their children than women with poor knowledge (P &lt;0.001). Conclusion: There is poor knowledge of HPV and practice of vaccination among mothers in llorin. Willingness of mothers to vaccinate their daughters is suboptimal. Mother’s knowledge is an important determinant of HPV vaccination of adolescents

Decontamination of T-2 Toxin in Maize by Modified Montmorillonite Clay

Montmorillonite clay has a wide range of applications, one of which includes the binding of mycotoxins in foods and feeds through adsorption. T-2 toxin, produced by some Fusarium,Myrothecium, and Stachybotrys species, causes dystrophy in the brain, heart, and kidney. Various formulations that include lemongrass essential oil-modified montmorillonite clay (LGEO-MMT), lemongrass powder (LGP), montmorillonite clay washed with 1mMNaCl (Na-MMT),montmorillonite clay (MMT), and lemongrass powder mixed with montmorillonite clay (LGP-MMT) were applied to maize at concentrations of 8% and 12% and stored for a period of onemonth at 30 �C. Unmodifiedmontmorillonite clay and LGP served as the negative controls alongside untreated maize. Fourier Transform Infrared (FTIR) spectra of the various treatments showed themajor functional groups as Si-O and -OH. All treatment formulationswere effective in the decontamination of T-2 toxin inmaize. Accordingly, itwas revealed that the inclusion ofNa-MMT in maize atMontmorillonite clay has a wide range of applications, one of which includes the binding of mycotoxins in foods and feeds through adsorption. T-2 toxin, produced by some Fusarium,Myrothecium, and Stachybotrys species, causes dystrophy in the brain, heart, and kidney. Various formulations that include lemongrass essential oil-modified montmorillonite clay (LGEO-MMT), lemongrass powder (LGP), montmorillonite clay washed with 1mMNaCl (Na-MMT),montmorillonite clay (MMT), and lemongrass powder mixed with montmorillonite clay (LGP-MMT) were applied to maize at concentrations of 8% and 12% and stored for a period of onemonth at 30 �C. Unmodifiedmontmorillonite clay and LGP served as the negative controls alongside untreated maize. Fourier Transform Infrared (FTIR) spectra of the various treatments showed themajor functional groups as Si-O and -OH. All treatment formulationswere effective in the decontamination of T-2 toxin inmaize. Accordingly, itwas revealed that the inclusion ofNa-MMT in maize at a concentration of 8% was most effective in decontaminating T-2 toxin by 66% in maize followed by LGP-MMT at 12% inclusion level recording a 56% decontamination of T-2 toxin in maize (p = 0.05). Montmorillonite clay can be effectivelymodified with plant extracts for the decontamination of T-2 toxin a concentration of 8% was most effective in decontaminating T-2 toxin by 66% in maize followed by LGP-MMT at 12% inclusion level recording a 56% decontamination of T-2 toxin in maize (p = 0.05). Montmorillonite clay can be effectivelymodified with plant extracts for the decontamination of T-2 toxi

Thermogravimetric Analysis of Modified Montmorillonite Clay for Mycotoxin Decontamination in Cereal Grains

-ermogravimetric analysis (TGA) was carried out to study the stability of nanoformulations used for the decontamination of mycotoxins. -e TGA patterns of the nanoformulations from montmorillonite clay and Cymbopogon citratus (lemongrass) extracts were assessed with temperature ranging from ambient (20°C) to 1000°C. -e various nanoformulations studied included unmodified montmorillonite clay (Mont), montmorillonite washed with sodium chloride (Mont-Na), montmorillonite mixed with lemongrass essential oil (Mont-LGEO), and montmorillonite mixed with an equal quantity of lemongrass powder (Mont- LGP). -ere was no significant difference in the median of the various nanoformulations within 4 weeks at p < 0.05 using the Kruskal–Wallis nonparametric test. For the TGA, the first degradation for montmorillonite clay and the nanoformulations occurred at a temperature between 80 and 101°C and was attributed to the loss of lattice water outside the coordination sphere with a range of 3.5–6.5% weight loss. -e second degradation occurred within the temperature of 338 to 344°C, and the third, at a temperature between 640 and 668°C for Mont and the formulations of Mont-Na, Mont-LGEO, and Mont-LGP. -ere were strong similarities in the degradation patterns of Mont and Mont-Na with the minimum difference being the relatively higher weight loss of the sodium-exchanged cation for Mont-Na at the third degradation step. Hence, the order of stability from the most resistant to the least resistant to degradation is as follows: Mont-LGEO ≥ Mont-Na ≥ Mont ≥ Mont-LGP

Chemical constituents, antiinflammatory and antinociceptive activities of essential oils from Cordia millenii, Bougainvillea glabra and Phyllanthus muellerianus

Essential oils were obtained by hydrodistillation of air-dry leaves of Cordia millenii Bak. (Boraginaceae), Bougainvillea glabra Choisy (Nyctaginaceae) and Phyllanthus muellerianus (Kuntze) Exell. (Euphorbiaceae) using a Clevenger-type apparatus. The chemical constituents of the oils were analyzed by gas chromatography and gas chromatography-mass spectrometry on an HP-5MS column. The major constituents of C. millenii were limonene (19.9%), diallyl disulfide (18.4%), β-caryophyllene (16.6%) and linalool (13.4%) while (E)-nerolidol (31.4%), (E)-β-ionone (10.3%) and linalool (10.1%) were present in B. glabra. Hexahydrofarnesyl acetone (11.6%), isocaryophyllene (9.8%) and limonene (9.4%) occurred in higher proportions in P. muellerianus. The antinociceptive properties of C. millenii oil were statistically not significantly different (p>0.05) when compared to the control for most tested concentrations except at the 120th minute (p0.05) when compared to the control. The antinociceptive properties of the essential oil of B. glabra were statistically significantly different, p<0.05 and p<0.01 at the doses of 100 and 200 mg/kg p.o., respectively, when compared to the control at the 30th minute but much more effective (p <0.001) at a dose of 400 mg/kg. For the 1st and 2nd hour, at the doses of 100 and 200 mg/kg (p <0.001), the antiinflammatory activity was statistically significantly (very low values of p) different from the control, while at the 3rd hour, it was significant (p <0.01) at a dose of 300 mg/kg but there were no statistical differences observable at the 4th hour. The essential of P. muellerianus at 100 mg/kg p.o. displayed an increased antinociceptive activity with p<0.01 to p <0.001 from the 30th to the 120th minute. Moreover, the oil showed a high inhibition, with up to p <0.001, in the case of carrageenan-induced inflammation

Pediatric Bacterial Meningitis Surveillance in Nigeria From 2010 to 2016, Prior to and During the Phased Introduction of the 10-Valent Pneumococcal Conjugate Vaccine

Background: Historically, Nigeria has experienced large bacterial meningitis outbreaks with high mortality in children. Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae are major causes of this invasive disease. In collaboration with the World Health Organization, we conducted longitudinal surveillance in sentinel hospitals within Nigeria to establish the burden of pediatric bacterial meningitis (PBM). Methods: From 2010 to 2016, cerebrospinal fluid was collected from children <5 years of age, admitted to 5 sentinel hospitals in 5 Nigerian states. Microbiological and latex agglutination techniques were performed to detect the presence of pneumococcus, meningococcus, and H. influenzae. Species-specific polymerase chain reaction and serotyping/grouping were conducted to determine specific causative agents of PBM. Results: A total of 5134 children with suspected meningitis were enrolled at the participating hospitals; of these 153 (2.9%) were confirmed PBM cases. The mortality rate for those infected was 15.0% (23/153). The dominant pathogen was pneumococcus (46.4%: 71/153) followed by meningococcus (34.6%: 53/153) and H. influenzae (19.0%: 29/153). Nearly half the pneumococcal meningitis cases successfully serotyped (46.4%: 13/28) were caused by serotypes that are included in the 10-valent pneumococcal conjugate vaccine. The most prevalent meningococcal and H. influenzae strains were serogroup W and serotype b, respectively. Conclusions: Vaccine-type bacterial meningitis continues to be common among children <5 years in Nigeria. Challenges with vaccine introduction and coverage may explain some of these finding. Continued surveillance is needed to determine the distribution of serotypes/groups of meningeal pathogens across Nigeria and help inform and sustain vaccination policies in the countr

Pediatric Bacterial Meningitis Surveillance in Nigeria From 2010 to 2016, Prior to and During the Phased Introduction of the 10-Valent Pneumococcal Conjugate Vaccine.

BACKGROUND: Historically, Nigeria has experienced large bacterial meningitis outbreaks with high mortality in children. Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae are major causes of this invasive disease. In collaboration with the World Health Organization, we conducted longitudinal surveillance in sentinel hospitals within Nigeria to establish the burden of pediatric bacterial meningitis (PBM). METHODS: From 2010 to 2016, cerebrospinal fluid was collected from children <5 years of age, admitted to 5 sentinel hospitals in 5 Nigerian states. Microbiological and latex agglutination techniques were performed to detect the presence of pneumococcus, meningococcus, and H. influenzae. Species-specific polymerase chain reaction and serotyping/grouping were conducted to determine specific causative agents of PBM. RESULTS: A total of 5134 children with suspected meningitis were enrolled at the participating hospitals; of these 153 (2.9%) were confirmed PBM cases. The mortality rate for those infected was 15.0% (23/153). The dominant pathogen was pneumococcus (46.4%: 71/153) followed by meningococcus (34.6%: 53/153) and H. influenzae (19.0%: 29/153). Nearly half the pneumococcal meningitis cases successfully serotyped (46.4%: 13/28) were caused by serotypes that are included in the 10-valent pneumococcal conjugate vaccine. The most prevalent meningococcal and H. influenzae strains were serogroup W and serotype b, respectively. CONCLUSIONS: Vaccine-type bacterial meningitis continues to be common among children <5 years in Nigeria. Challenges with vaccine introduction and coverage may explain some of these finding. Continued surveillance is needed to determine the distribution of serotypes/groups of meningeal pathogens across Nigeria and help inform and sustain vaccination policies in the country

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10&nbsp;years; 78.2% included were male with a median age of 37&nbsp;years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020