2,359 research outputs found
Tlön, Uqbar y Orbis Tertius
El propĂłsito de este trabajo es demostrar que la primera parte
del relato, el descubrimiento de Uqbar, es el espejo en el cual se
reflejan amplificadas y con más complejidad la segunda parte del
mismo, el descubrimiento de Tlön, y la posdata de 1947, el cedimiento
de una realidad empĂrica, la Tierra material, a la nueva realidad de
Orbis Tertius. De esta forma, su estructura refleja adecuadamente el
contenido del relato, la necesidad humana de crear sistemas deseables
para explicarse la realidad, los cuales se transforman eventualmente
en nuestro mundo de la realidad. Esta, a su vez, sujeta al Ămpetu
del cambio histórico, cederá inexorablemente a otra y mejor
idea.Fil: Leo de Belmont, Laura.
Universidad Nacional de Cuyo. Facultad de FilosofĂa y Letra
Changes in total choline concentration in the breast of healthy fertile young women in relation to menstrual cycle or use of oral contraceptives: a 3-T 1H-MRS study
BACKGROUND:
To evaluate changes in total choline (tCho) absolute concentration ([tCho]) in the breast of healthy fertile women in relation to menstrual cycle (MC) or use of oral contraceptives (OC).
METHODS:
After institutional review board approval, we prospectively evaluated 40 healthy fertile volunteers: 20 with physiological MC, aged 28 ± 3 years (mean ± standard deviation; nOC group); 20 using OC, aged 26 ± 3 years (OC group). Hormonal assays and water-suppressed single-voxel 3-T proton magnetic resonance spectroscopy (1H-MRS) were performed on MC days 7, 14, and 21 in the nOC group and only on MC day 14 in the OC group. [tCho] was measured versus an external phantom. Mann-Whitney U test and Spearman coefficient were used; data are given as median and interquartile interval.
RESULTS:
All spectra had good quality. In the nOC group, [tCho] (mM) did not change significantly during MC: 0.8 (0.3-2.4) on day 7, 0.9 (0.4-1.2) on day 14, and 0.4 (0.2-0.8) on day 21 (p = 0.963). In the OC group, [tCho] was 0.7 (0.2-1.7) mM. The between-groups difference was not significant on all days (p ≥ 0.411). All hormones except prolactin changed during MC (p ≤ 0.024). In the OC group, [tCho] showed a borderline correlation with estradiol (r = 0.458, p = 0.056), but no correlation with other hormones (p ≥ 0.128). In the nOC group, [tCho] negatively correlated with prolactin (r = -0.587, p = 0.006) on day 7; positive correlation was found with estradiol on day 14 (r = 0.679, p = 0.001).
CONCLUSIONS:
A tCho peak can be detected in the normal mammary gland using 3-T 1H-MRS. The [tCho] in healthy volunteers was 0.4-0.9 mM, constant over the MC and independent of OC use
Recoverable Robustness for Railway Rolling Stock Planning
In this paper we explore the possibility of applying the notions
of Recoverable Robustness and Price of Recoverability (introduced
by [5]) to railway rolling stock planning, being interested in recoverability measures that can be computed in practice, thereby evaluating the robustness of rolling stock schedules. In order to lower bound the Price of Recoverability for any set of recovery algorithms, we consider an "optimal" recovery algorithm and propose a Benders decomposition approach to assess the Price of Recoverability for this "optimal" algorithm. We evaluate the approach on real-life rolling stock planning problems of NS, the main operator of passenger trains in the Netherlands. The preliminary results show that, thanks to Benders decomposition, our lower bound can be computed within relatively short time for our case study
Robust Train Routing and Online Re-scheduling
Train Routing is a problem that arises in the early phase of
the passenger railway planning process, usually several months
before operating the trains. The main goal is to assign each
train a stopping platform and the corresponding arrival/departure
paths through a railway station. It is also called Train Platforming when
referring to the platform assignment task. Railway stations often represent
bottlenecks and train delays can easily disrupt the routing schedule.
Thereby railway stations are responsible for a large part of the delay
propagation in the whole network. In this research we present
different models to compute robust routing schedules and we study
their power in an online context together with different re-scheduling
strategies. We also design a simulation framework and use it to evaluate
and compare the effectiveness of the proposed robust models and re-scheduling
algorithms using real-world data from Rete Ferroviaria Italiana, the main
Italian Railway Infrastructure Manager
Long-range order in arrays of composite and monolithic magneto-toroidal moments
Magneto-toroidal order, also called ferrotoroidicity, is the most recently
established type of ferroic state. It is based on a spontaneous and uniform
alignment of unit-cell-sized magnetic whirls, called magneto-toroidal moments,
associated with a macroscopic toroidization. Because of its intrinsic
magnetoelectric coupling, this new ferroic state could be useful in the
development of spintronic devices. We exploit two-dimensional periodic arrays
of magnetostatically coupled nanomagnets as model systems for the investigation
of long-range magneto-toroidal order. We present two pathways promoting this
order, namely (i), structures comprising a ring of uniformly magnetized
sub-micrometer-sized bar magnets and (ii), structures in which each magnetic
building block itself hosts a magnetic vortex. For both cases calculations of
the magnetic-dipole interaction and micromagnetic simulations reveal the
conditions for the formation of spontaneous magneto-toroidal order. We confirm
this order and the formation of magneto-toroidal domains in our arrays by
magnetic force microscopy. We identify the presence of two types of domain-wall
states emerging from the competition of two intrinsic microscopic couplings.
Our work not only identifies the microscopic conditions promoting spontaneous
magneto-toroidal order but also highlights the possibility tailor mesoscale
magnetic arrays towards elusive types of ferroic order.Comment: 20 pages, 7 figure
- …