28 research outputs found
Promoting fintech financing for SME in S. Caucasian and Baltic States, during the Covid-19 global pandemic
Purpose – to analyse the digitalization trends in the Central Caucasian (Georgia, Azerbaijan and Armenia) and Baltic States with the aim of reducing a financial gap for the Small and Medium size Enterprises in Georgia, Azerbaijan and Armenia.
Research methodology – comparative analysis between Baltic and Caucasian countries are made to analyse the basic positions and farther development opportunities for Georgia, Azerbaijan and Armenia.
Findings of the given paper – while SME sector crucially important contributor to employment, diversification and productivity in any country of the world and especially in developing ones, they still face significant credit constraints through traditional credit providing institutions. However, the trend is changing and modern digital technologies from the fintech area are providing new alternatives, which already had been widely used in Baltic, but still are waiting their chance in Georgia, Azerbaijan and Armenia, with different level of progress and readiness.
Research limitations – some statistical data does not exist for all six countries or were possible to obtain for different periods of time. Lack of academic literature on fintech in Caucasian countries.
Practical implications – It can provide a useful perspective for researchers, academics, investors, investment managers, decision-makers, and scientists.
Originality/Value – The paper analyses three advanced European Union member state’s (Lithuania, Latvia and Estonia) fintech positions and perspectives as a model of development for three developing Caucasian states (Georgia, Azerbaijan and Armenia)
Phenotypic and genotypic variations within a single bacteriophage species
<p>Abstract</p> <p>Background</p> <p>Although horizontal gene transfer plays a pivotal role in bacteriophage evolution, many lytic phage genomes are clearly shaped by vertical evolution. We investigated the influence of minor genomic deletions and insertions on various phage-related phenotypic and serological properties.</p> <p>Findings</p> <p>We collected ten different isolates of <it>Pseudomonas aeruginosa </it>bacteriophage ϕKMV. All sequenced genomes (42-43 kb, long direct terminal repeats) are nearly identical, which intuitively implied strongly similar infections cycles. However, their latent periods vary between 21 and 28 minutes and they are able to lyse between 5 and 58% of a collection of 107 clinical <it>P. aeruginosa </it>strains. We also noted that phages with identical tail structures displayed profound differences in host spectra. Moreover, point mutations in tail and spike proteins were sufficient to evade neutralization by two phage-specific antisera, isolated from rabbits.</p> <p>Conclusion</p> <p>Although all analyzed phages are 83-97% identical at the genome level, they display a surprisingly large variation in various phenotypic properties. The small overlap in host spectrum and their ability to readily escape immune defences against a nearly identical phage are promising elements for the application of these phages in phage therapy.</p
Quality-Controlled Small-Scale Production of a Well-Defined Bacteriophage Cocktail for Use in Human Clinical Trials
We describe the small-scale, laboratory-based, production and quality control of a cocktail, consisting of exclusively lytic bacteriophages, designed for the treatment of Pseudomonas aeruginosa and Staphylococcus aureus infections in burn wound patients. Based on succesive selection rounds three bacteriophages were retained from an initial pool of 82 P. aeruginosa and 8 S. aureus bacteriophages, specific for prevalent P. aeruginosa and S. aureus strains in the Burn Centre of the Queen Astrid Military Hospital in Brussels, Belgium. This cocktail, consisting of P. aeruginosa phages 14/1 (Myoviridae) and PNM (Podoviridae) and S. aureus phage ISP (Myoviridae) was produced and purified of endotoxin. Quality control included Stability (shelf life), determination of pyrogenicity, sterility and cytotoxicity, confirmation of the absence of temperate bacteriophages and transmission electron microscopy-based confirmation of the presence of the expected virion morphologic particles as well as of their specific interaction with the target bacteria. Bacteriophage genome and proteome analysis confirmed the lytic nature of the bacteriophages, the absence of toxin-coding genes and showed that the selected phages 14/1, PNM and ISP are close relatives of respectively F8, φKMV and phage G1. The bacteriophage cocktail is currently being evaluated in a pilot clinical study cleared by a leading Medical Ethical Committee
Rola miast w systemie usług dla ludności rolniczej w subtropikalnej strefie Gruzińskiej SSR
Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej naukę
Projective Geometry of Moduli and Lie Algebras
Available from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio
COVID-19 effect on FDI motivation and their impact on service sector: Case of Georgia
Based on the Scott-Kennel’s model of local industry upgrade through foreign direct investments, this paper analyses if investments are always positively benefiting the host economy, or if they are not promoting local/host economies at all, or to which exact level. This paper is focused on service sector oriented investments and answers the questions important to analyse for the successful investment policy creation, which could benefit both the local economy and foreign investors. In other words, only aggregated per year foreign investment numbers are not enough for the comprehensive picture creation and in some cases could even suggest incorrect strategic decisions. Research was done based on deep interviews with the top management of 20 different companies listed in top 200 FDI making companies in Georgia for the 2020 year. Paper considers the global pandemic reality and future perspectives
Economic cooperation between Central Caucasus, China, and EU, under COVID-19 challenges
Study analyses the China’s Belt and Road Initiative perspectives for EU and Central Caucasus countries of Georgia, Armenia and Azerbaijan, with the special focus on covid-19 global pandemic reality. Trade, investments and transit is considered as main factors of the given paper. At the same time, global competition for leadership, open and hidden trade and investment wars are taken into account. Study also suggest different alternative ways of including Central Caucasian states into the project as a corridor for China – EU connection. Coronomic challenges are considered as a new wave of challenge and at the same time as a new opportunity for all counterparts, depending on potential, vision and activities they will conduct in the nearest future
The Caucasus 3 plus the Baltic 3 and economic cooperation with China
This study analyses China’s One Belt, One Road (OBOR) initiative for the Baltic and South Caucasus countries. Trade, Foreign Direct Investments and transit potential are taken as main factors for the cooperation. A clash of China and the West in pursuing economic leadership is taken into account. The study suggests a new, alternative route for the OBOR initiative through the Caucasus, which has all the needed infrastructure and readiness for being started. Moreover, Georgia is not new to the EU preferences, it has experience of GSP+ and now the unique achievement of free trade regimes with the EU and China is also taken as an alternative route and an advantage for the Caucasus and the Baltic States. Keywords: 16+1 cooperation, Baltic States, BRI, Caucasus, FDI, international trade, OBO