Certain features of using modified collagen-containing raw materials with prolonged shelf life in food technology

In the current circumstances, trends in nutrition of a person striving to lead a healthy life-style require intake of meat products with the reduced energy value, minimal amounts of fat, increased protein mass fraction, presence of substances improving homeostasis of the body. The synergism of the modern nutrition science and meat industry enables creating food products that satisfy consumers’ demand. Today, in the Russian Federation, a theoretical and practical base of the technology development has been collected to the full extent in the field of rational processing of secondary raw materials in the food industry, optimal use of animal secondary raw materials, study of the protein ingredients of animal and plant origin and their deep scientifically substantiated processing, improvement of technological processes and equipment, and correspondently, product range extension. The paper broadens the information about the modified collagen-containing raw materials (cattle rumen), examines physico-chemical characteristics of the collagen-containing raw material and its changes in the process of freeze-drying with a special attention paid to the study of changes in the histological structure. The presence of the relatively uniform fibrillar structure was determined, which facilitated discovering the functional potential of proteinoids that form the fibrillar matrix in the composition of products from different groups. Analysis of IR-spectra revealed several significant absorption bands linked with the state of peptide bonds. The character of bands is linked with the complex of valence and deformation vibrations of the N- and С- types. It is believed that IR-spectra reflect conformations in the protein secondary structure, which suggests preserving properties of the tropocollagen particle or collagen molecule. Freeze-dried modified collagen-containing cattle rumen was tested by the example of jellies. The obtained databank broadens information about physico-chemical properties of modified collagen-containing raw materials (cattle rumen).In the current circumstances, trends in nutrition of a person striving to lead a healthy life-style require intake of meat products with the reduced energy value, minimal amounts of fat, increased protein mass fraction, presence of substances improving homeostasis of the body. The synergism of the modern nutrition science and meat industry enables creating food products that satisfy consumers’ demand. Today, in the Russian Federation, a theoretical and practical base of the technology development has been collected to the full extent in the field of rational processing of secondary raw materials in the food industry, optimal use of animal secondary raw materials, study of the protein ingredients of animal and plant origin and their deep scientifically substantiated processing, improvement of technological processes and equipment, and correspondently, product range extension. The paper broadens the information about the modified collagen-containing raw materials (cattle rumen), examines physico-chemical characteristics of the collagen-containing raw material and its changes in the process of freeze-drying with a special attention paid to the study of changes in the histological structure. The presence of the relatively uniform fibrillar structure was determined, which facilitated discovering the functional potential of proteinoids that form the fibrillar matrix in the composition of products from different groups. Analysis of IR-spectra revealed several significant absorption bands linked with the state of peptide bonds. The character of bands is linked with the complex of valence and deformation vibrations of the N- and С- types. It is believed that IR-spectra reflect conformations in the protein secondary structure, which suggests preserving properties of the tropocollagen particle or collagen molecule. Freeze-dried modified collagen-containing cattle rumen was tested by the example of jellies. The obtained databank broadens information about physico-chemical properties of modified collagen-containing raw materials (cattle rumen)

Wernicke encephalopathy after sleeve gastrectomy

The article describes the case of a patient with Wernicke encephalopathy, which developed 3 months after the sleeve gastrectomy. An MRI of the brain was performed to verify the diagnosis, which revealed a symmetrical non-uniform increase in the MR signal on T2-WI and Tirm from the medial part of the thalamus, mastoid bodies and gray matter around the aqueduct of Sylvius. Thiamine infusion was promptly initiated as therapy. During treatment, acute neurological symptoms almost regressed, the patient was discharged in a satisfactory condition with preservation of vertical nystagmus under the supervision of specialists at the place of residence. Wernicke–Korsakoff syndrome more often occurs as a complication of alcoholism and arising from thiamine deficiency. However, the fact that this condition also occurs under the influence of other etiopathogenetic factors is often ignored by clinicians. In the management of patients after bariatric interventions, this condition is much more common in malabsorptive operations. However, a combination of certain factors can be described in patients after restrictive types of bariatric surgeries

Comparative Analysis of Clinical, Hormonal and Morphological Studies in Patients with Neuroendocrine ACTH-Producing Tumours

This paper highlights the problem of neuroendocrine tumours (NETs) with clinical symptoms of hypercorticism caused by hypersecretion of adrenocorticotropic hormone (ACTH) by tumour cells. In most cases (85%), the tumours were localized in the pituitary gland (Cushing's disease); 15% of the patients had an extrapituitary tumour that manifest as an ectopic ACTH secretion (EAS). Comparative analysis of clinical, hormonal, histological, and immunohistochemical characteristics of pituitary and extrapituitary ACTH-secreting NET was performed. It included 46 patients with CD and 38 ones exhibiting ectopic ACTH secretion (EAS). Results of the study suggest differences between CD and EAS in terms of the severity of clinical manifestations and duration of the disease. Hormonal studies showed that EAS unlike CD was associated with high plasma ACTH and cortisol levels, late-evening salivary cortisol and daily urinary free cortisol, the absence of a 60% or greater reduction of cortisol in the HDDST test, and the presence of a low (less than 2) ACTH gradient in response to desmopressin administration with catheterization of cavernous sinuses. The study of morphofunctional characteristics of the removed NET demonstrated the ability of both pituitary and extrapituitary NETs to express ACTH as well as GH, PRL, LH, and FSH. The angiogenic markers (CD31 and VEGF) were detected with equal frequency regardless of the NET localization. The histological structure of all corticotropinomas suggested their benign origin, but extrapituitary NETs were represented by different morphological types with varying malignancy, invasiveness, and metastatic properties. A higher cell proliferation potential (Ki-67) was documented for NET in patients presenting with an ectopic ACTH secretion compared to those having corticotropinomas

System-dynamic modeling of the development of universities in the conditions of informatization

The work is devoted to the selection of key performance indicators (KPI) of universities, as well as the development of the concept of using these indicators in assessing the effectiveness of universities in the scientific and innovative sector of Russia. The study used a combination of descriptive and deductive methods, as well as experiment. There were analyzed the data on financing, the number of publications indexed in the Web of Science, as well as the number of employees of 14 Russian universities that have been participating since 2013 in the state program "Project 5-100". This program is aimed at the adaptation of Russian universities to international standards and incorporating them into international education environment. A system-dynamic model is constructed that allows, on the basis of the key performance indicators, to find new approaches and ways to achieve the goals set and to build an effective university development strategy in the transition to a digital economy. © 2020 American Institute of Physics Inc.. All rights reserved

Anthropogenic- and natural sources of dust in peatland during the Anthropocene

As human impact have been increasing strongly over the last decades, it is crucial to distinguish human-induced dust sources from natural ones in order to define the boundary of a newly proposed epoch - the Anthropocene. Here, we track anthropogenic signatures and natural geochemical anomalies in the Mukhrino peatland, Western Siberia. Human activity was recorded there from cal AD 1958 (±6). Anthropogenic spheroidal aluminosilicates clearly identify the beginning of industrial development and are proposed as a new indicator of the Anthropocene. In cal AD 1963 (±5), greatly elevated dust deposition and an increase in REE serve to show that the geochemistry of elements in the peat can be evidence of nuclear weapon testing; such constituted an enormous force blowing soil dust into the atmosphere. Among the natural dust sources, minor signals of dryness and of the Tunguska cosmic body (TCB) impact were noted. The TCB impact was indirectly confirmed by an unusual occurrence of mullite in the pea

Comparison of gingival retraction methods

Dentists use materials for retraction of the gingival sulcus daily in their practice. Effective gingival retraction prior to taking an impression without damaging periodontal tissues is very important for the long-term success of restorative treatment. The article analyzes the most commonly used methods of retractionВрачи-стоматологи ежедневно применяют в своей практике ретракцию десневой борозды. Эффективная ретракция десны до снятия оттиска без повреждения тканей пародонта очень важна для долгосрочного успеха реставрационного лечения. В статье проведен анализ наиболее часто используемых методов ретракци

Research of the Maturity of Deed Among Students with Different Locus of Control

Оригинал статьи получен 15 апреля 2024. Исправленная статья принята 02 мая 2024.Статья посвящена изучению различий в уровне зрелости поступков у студентов с разным локусом контроля. Актуальность данного исследования свя­зана с развитием в России персонализированного образования в высших учебных заведениях. В условиях, когда студент сам может выбрать наполнение части образо­вательной программы, результат будет зависеть от его способности делать, по сути, жизненно важный выбор. Локус контроля рассматривается как один из существен­ных факторов, определяющих качество выбора для самого студента. Представлены материалы эмпирического исследования, полученные на выборке студентов, обуча­ющихся в системе высшего образования г. Тюмени. В исследовании приняли участие 98 человек в возрасте от 17 до 27 лет (М =19.61; SD = 1.8), из которых 25.5 % мужчин, 74.5 % женщин. Использовались следующие методики: «Опросник исследования уровня субъективного контроля (УСК)» Дж. Роттера, адаптированный Е. Ф. Бажиным, Е. А. Голынкиной, Л. М. Эткиндом для определения локуса контроля и «Исследование поступков» В. А. Старцевой, Е. Л. Доценко, О. В. Пчелиной для выявления уровня зре­лости поступка. Методы статистической обработки: описательный и сравнительный анализ. Полученные результаты дают возможность говорить о том, что существует статистически значимое различие в уровне зрелости поступков у студентов с интернальным и экстернальным локусом контроля. Уровень зрелости поступков значимо выше у участников с интернальным локусом контроля. Испытуемые с интернальным локусом контроля при решении диагностической задачи используют более широкий репертуар поступков.The article is devoted to the study of differences in the level of maturity of the deed among students with different locus of control. The relevance of this study is related to the development of personalized education in higher education institutions in Russia. In conditions where the student can choose the content of a part of the educational program, the result will depend on his ability to make, in fact, vital choice. Locus of control is considered as one of the essential factors determining the quality of choice for the student himself. The materials of empirical research obtained from a sample of students studying in the higher education system of Tyumen are presented. 98 people aged 17 to 27 years (M= 19.61; SD = 1.8) took part in the research. Of these, 25.5 % were men, 74.4 % were women. The methods used were “Questionnaire for the study of the level of subjective control (USC)” by J. Rotter, adapted by E. E Bazhin, E. A. Golynkina, L. M. Etkind to determine the locus of control and “Research of Deeds” by V. A. Startseva, E. L. Dotsenko, O. V. Pchelina to identify the level of maturity of the deed. Methods of statistical processing: descriptive statistics, comparative analysis. The results obtained make it possible to say that there is a statistically significant difference in the level of maturity of the deed among students with an internal and external locus of control. The level of maturity of deeds is significantly higher in participants with an internal locus of control. Participants with an internal locus of control use a wider repertoire of deeds when solving a diagnostic task

Analysis of the structure of validity of appeals of citizens insured under the MHI system regarding the quality of medical care in the field of otorhinolaryngology in the Sverdlovsk region at the level of outpatient and inpatient care

The purpose of the study is to analyze defects in the quality of medical care in the direction of "otorhinolaryngology" in the Sverdlovsk region, as well as to study the structure of citizens' appeals on the provision of medical care.Цель исследования. Анализ дефектов качества оказания медицинской помощи по профилю «оториноларингология» в Свердловской области, а также изучение структуры обращений граждан по вопросам оказания медицинской помощи

Role of radiological methods of diagnostics at simultaneous pancreas-kidney transplantation

Aim of investigation. To characterize radiological methods of diagnostics of surgical complications after simultateous pankreas-kidney transplantation (SPKT).Material and methods. From January, 2008 to June, 2014 overall 40 patients with the type 1 diabetes mellitus complicated by terminal diabetic nephropathy, underwent SPKT, including 17 cases (42,5%) — of intraperitoneal transplantation and 23 (57,5%) — of retroperitoneal transplantation. Mean age of patients was 35,7±6,36 year. Of all recipients 19 were women (47,5%) and 21 — men (52,5%). Results. Of 15 patients after SPKT 21 surgical complications were diagnosed, overwhelming majority of them have been corrected successfully. Only in one case the pancreatic transplant was lost due to postoperative surgical complications.Conclusions. Duly diagnostics and the proven choice of miniinvasive techniques for treatment of surgical complications became possible due to wide and urgent application of the whole spectrum of available radiological methods