Comparing a mobile decision support system versus the use of printed materials for the implementation of an evidence-based recommendation : protocol for a qualitative evaluation

1-9Background: The distribution of printed materials is the most frequently used strategy to disseminate and implement clinical practice guidelines, although several studies have shown that the effectiveness of this approach is modest at best. Nevertheless, there is insufficient evidence to support the use of other strategies. Recent research has shown that the use of computerized decision support presents a promising approach to address some aspects of this problem. Objective: The aim of this study is to provide qualitative evidence on the potential effect of mobile decision support systems to facilitate the implementation of evidence-based recommendations included in clinical practice guidelines. Methods: We will conduct a qualitative study with two arms to compare the experience of primary care physicians while they try to implement an evidence-based recommendation in their clinical practice. In the first arm, we will provide participants with a printout of the guideline article containing the recommendation, while in the second arm, we will provide participants with a mobile app developed after formalizing the recommendation text into a clinical algorithm. Data will be collected using semistructured and open interviews to explore aspects of behavioral change and technology acceptance involved in the implementation process. The analysis will be comprised of two phases. During the first phase, we will conduct a template analysis to identify barriers and facilitators in each scenario. Then, during the second phase, we will contrast the findings from each arm to propose hypotheses about the potential impact of the system. Results: We have formalized the narrative in the recommendation into a clinical algorithm and have developed a mobile app. Data collection is expected to occur during 2018, with the first phase of analysis running in parallel. The second phase is scheduled to conclude in July 2019. Conclusions: Our study will further the understanding of the role of mobile decision support systems in the implementation of clinical practice guidelines. Furthermore, we will provide qualitative evidence to aid decisions made by low- and middle-income countries’ ministries of health about investments in these technologies

Natural Wormholes as Gravitational Lenses

Visser has suggested traversable 3-dimensional wormholes that could plausibly form naturally during Big Bang inflation. A wormhole mouth embedded in high mass density might accrete mass, giving the other mouth a net *negative* mass of unusual gravitational properties. The lensing of such a gravitationally negative anomalous compact halo object (GNACHO) will enhance background stars with a time profile that is observable and qualitatively different from that recently observed for massive compact halo objects (MACHOs) of positive mass. We recommend that MACHO search data be analyzed for GNACHOs.Comment: 4 pages; plus 4 figures; ReV_TeX 3.0; DOE/ER/40537-001/NPL94-07-01

The Grizzly, December 5, 1986

Alleluia! Alleluia!: French Presents Handel\u27s Messiah • New Modernistic Sculpture To Arrive • Preparing For the Aggressive Couple • Editorial: Drug Testing Wrap • Letters: Ronning Still Steamed; Challenge vs. Pro-Choice; Nagy Raises More Questions on Abortion; Conrad, Get Your Labyrinth!; Women\u27s Studies Holds Various Viewpoints; Women\u27s Studies Program Defined • Ursinus Art Showcase to Grow • Faculty Fat Farm • Love Me Do to Revolution : Pat Mancuso\u27s Seen it All • Mermen Immersed In Swim Season • Bears Open Strong With 114-52 Thrashing vs. Mount St. Vincent, but Then Slump • Freshman Hacker Anything but Choppy For Men Harriers • Seesaw Beginning for Lady Bears • Another Club Cornered: Circle K Serves Community • Landis Traces Course of Adventhttps://digitalcommons.ursinus.edu/grizzlynews/1177/thumbnail.jp

The Grizzly, March 25, 1988

Alcohol Abuse Abounds • Abortion Forum Caused Little Racket • Conwell is Here! • Selected Speakers: Berry and Connolly • Letters: Women More Than Miffed; Task Force Wants You; Applause to Participants; We Want Service, Too!; Track Awards Noted • Easter Reflections on Zacharias • Developing Student Life • Major Math • Jazz! • MAC Honors Outstanding Student-Athletes • Lady Bears Steel Show • Baseball Pitches Win • Bears Make Tracks • Lax is Ready! • Gym-Nastics • Ursinus Men Strut Their Stuff • Berry: Up Close and Personal • Organ Virtuoso to Perform • McCullough\u27s Safety Tips • Rally Round Nally • Now and Zen Up and Coming • The Zoo\u27s the News • Dying Boy, 6 Needs Helphttps://digitalcommons.ursinus.edu/grizzlynews/1209/thumbnail.jp

Publically different, privately the same: Gender differences and similarities in response to Facebook status updates

Social networking sites (SNS), and especially Facebook, have revolutionised patterns of language and communication. We conducted a study to examine gender differences in language use on Facebook, by surveying 600 undergraduate students (388 females and 207 males), and analysing males’ and females’ responses to two Facebook status updates. There were a number of gender differences in terms of public replies to Facebook status updates. Females were significantly more likely to ‘Like’ a Facebook status update than males, post a public reply to a Facebook status update than males and show higher levels of emotional support than males. In contrast there were hardly any gender differences in terms of sending private messages in response to Facebook status updates. There was no gender difference in terms of level of emotional support in private messages. Females were more likely to send a private message than males, but this difference was very small. The implications of these findings for explanations of gender differences in language are discussed

Mass fractionation of noble gases in synthetic methane hydrate : implications for naturally occurring gas hydrate dissociation

This paper is not subject to U.S. copyright. The definitive version was published in Chemical Geology 339 (2013): 242-250, doi:10.1016/j.chemgeo.2012.09.033.As a consequence of contemporary or longer term (since 15 ka) climate warming, gas hydrates in some settings may presently be dissociating and releasing methane and other gases to the ocean–atmosphere system. A key challenge in assessing the impact of dissociating gas hydrates on global atmospheric methane is the lack of a technique able to distinguish between methane recently released from gas hydrates and methane emitted from leaky thermogenic reservoirs, shallow sediments (some newly thawed), coal beds, and other sources. Carbon and deuterium stable isotopic fractionation during methane formation provides a first-order constraint on the processes (microbial or thermogenic) of methane generation. However, because gas hydrate formation and dissociation do not cause significant isotopic fractionation, a stable isotope-based hydrate-source determination is not possible. Here, we investigate patterns of mass-dependent noble gas fractionation within the gas hydrate lattice to fingerprint methane released from gas hydrates. Starting with synthetic gas hydrate formed under laboratory conditions, we document complex noble gas fractionation patterns in the gases liberated during dissociation and explore the effects of aging and storage (e.g., in liquid nitrogen), as well as sampling and preservation procedures. The laboratory results confirm a unique noble gas fractionation pattern for gas hydrates, one that shows promise in evaluating modern natural gas seeps for a signature associated with gas hydrate dissociation.Partial support for this research was provided by Interagency Agreements DE-FE0002911 and DE-NT0006147 between the U.S. Geological Survey Gas Hydrates Project and the U.S. Department of Energy's Methane Hydrates Research and Development Program

A longitudinal analysis of urological chronic pelvic pain syndrome flares in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151272/1/bju14783.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151272/2/bju14783_am.pd

A call for transparent reporting to optimize the predictive value of preclinical research

The US National Institute of Neurological Disorders and Stroke convened major stakeholders in June 2012 to discuss how to improve the methodological reporting of animal studies in grant applications and publications. The main workshop recommendation is that at a minimum studies should report on sample-size estimation, whether and how animals were randomized, whether investigators were blind to the treatment, and the handling of data. We recognize that achieving a meaningful improvement in the quality of reporting will require a concerted effort by investigators, reviewers, funding agencies and journal editors. Requiring better reporting of animal studies will raise awareness of the importance of rigorous study design to accelerate scientific progress