Exploratory Factor Analysis of the Trauma Symptom Checklist for Children: A Comparison of Two Factor Extraction Methods

INTRODUCTION: Assessment tools that demonstrate adequate construct validity are needed to identify youth at risk of developing posttraumatic stress symptoms (PTSS) so these at risk youth can be referred to appropriate resources such as counseling. Research on the construct validity of instruments designed to measure PTSS have not shown a consistent factor structure of PTSS. Furthermore, the factor structure of PTSS measured using the Trauma Symptom Checklist for Children (TSCC), a widely used instrument, have only been studied using principal component analysis (PCA), a data reduction technique, rather than exploratory factor analysis (EFA), a factor analytic technique. AIM: The present study aims to 1) evaluate the construct validity of the TSCC using EFA, and 2) demonstrate differences in factor solutions extracted using EFA and PCA. METHODS: A secondary data analysis was conducted on a sample of 121 adolescents exposed to community violence in a mid-sized southern city. Two factor analyses were conducted on the sample using EFA and PCA. RESULTS: Using EFA, PTSS measured by the TSCC demonstrated a three factor structure. The factors were named the Posttraumatic Stress factor, Fear factor, and Sexual Concerns factor. Using PCA, five less interpretable components were extracted. DISCUSSION: The factor structure of PTSS measured by the TSCC differed from currently proposed factor solutions in the PTSS literature, lending evidence that more EFA work is necessary to determine the factor structure of PTSS. As expected, there were also differences between the factor solutions produced using the two different analytic techniques. Future research is needed to confirm this factor solution in larger, more diverse samples

Student-Led Live Broadcast Tour: An Elevated Learning Journey for Tourism Students

The version of record of this article, first published in [SN Computer Science], is available online at Publisher’s website: http://dx.doi.org/10.1007/s42979-024-02729-0Drawing upon the concept of student-led live broadcasting tour (LBT), this study aims to construct and empirically test the Input-Process-Output (IPO) framework that links inputs, processes, and outputs within online tourism educational context. The sample involved students who are currently studying a tourism program in the Greater Bay Area, China. One group of students was invited as the audience with another group of students acting as tour guides to lead a live broadcasting tour. Upon completion of the tour, the audience group was invited to fll in the questionnaire survey. The data were gathered through the questionnaire survey from December 2022 to March 2023. The survey instruments were designed based on existing research and the IPO framework. The quantitative data were analysed by SPSS and SmartPLS. 5 hypotheses were developed based on the IPO framework. The results confrmed that students perceived student-led LBT positively in terms of input dimensions (intrinsic motivation and resources support), process dimension (learning climate) and output dimension (learning outcomes and satisfaction). This study gives implications to educators on how student-led LBT can be designed and implemented under the constraints of travel. The utilisation of technology ofers educators the possibility to enrich the learning experience of tourism students in a more afordable and efective way.unfunde

A Screening tool for Identification of Victims of Commercial Sexual Exploitation of Children

Background: Commercial sexual exploitation of children (CSEC) and sex trafficking have only recently been recognized as problems by healthcare providers. Both UNICEF (2014) and the Institute of Medicine (2013) have stressed the need for systematic research to assist healthcare providers in the identification of victims. The aim of this poster is to describe initial findings relating to the development of a screening tool to identify CSEC victims. Methods: Twenty-seven sites nationwide (e.g., emergency departments and specialized clinics) participated in a study to validate a screening tool for identifying CSEC victims in an outpatient setting. The study was conducted under approval from the Institutional Review Board at Children’s Healthcare of Atlanta. Inclusion criteria for the study generally involved being an English-speaking adolescent aged 11-18 years. Results: Study enrollment is ongoing. Preliminary data for 210 youth were analyzed for this abstract. The sample was diverse with respect to age (M=14.59 years, SD=1.490 years) and ethnicity (56.4% Caucasian, 31.8% African American, 3.9% mixed race, and 7.8% Hispanic); the sample was predominantly female (92.8%). Of the 210 youth in the sample, 115(54.8%) have had sex. Of these 115 youth, 13(11.3%) have traded sex for money, drugs, or housing; 7(58.3%) of 12(10.4%) complied when asked by someone to have sex with another person; 8(61.5%) of 13(11.3%) performed sexual acts in public when propositioned; and 19(45.2%) of 42(36.5%) shared provocative photos when prompted. Medical providers flagged 14 youth (6.7% of total 210) as potential CSEC victims. Conclusions: The screening tool shows promise for effective identification of CSEC victims. This poster will present additional data and further quantitative analyses exploring the influences of sexual behavior, drug and alcohol use, and other factors on the risk of becoming a CSEC victim. Implications for researchers and clinicians will also be discussed

Students of Color and COVID-19: Experiences, Coping Strategies, and Supports

The coronavirus disease of 2019, known as the COVID-19 pandemic, is a disaster event that posed significant physical, social, financial, and mental health risks to college students. Disproportionate experiences of stressors position students of color as a population particularly vulnerable to the negative impacts of COVID-19, thus, the current study assessed the impact of COVID-19 on undergraduate students of color in the United States. Students participated in semi-structured in-depth interviews about their experiences with stressors during the pandemic. Data were analyzed using conventional content analysis and revealed themes including (a) the pandemic’s impact on students; (b) basic needs as college students; (c) strategies used to cope with stressors; and (d) supports desired from institutions and faculty. Findings inform colleges and healthcare providers of the most salient concerns for students of color and the sources found helpful. As such, these findings may guide effective prevention and intervention strategies to minimize the effects of future disasters

Effects of Exposure to Community Violence and Family Violence on School Functioning Problems among Urban Youth: The Potential Mediating Role of Posttraumatic Stress Symptoms

Adolescents who are exposed to violence during childhood are at an increased risk for developing posttraumatic stress (PTS) symptoms. The literature suggests that violence exposure might also have negative effects on school functioning, and that PTS might serve as a potential mediator in this association. The purpose of the current study was to replicate and extend prior research by examining PTS symptoms as a mediator of the relationship between two types of violence exposure and school functioning problems among ado- lescent youth from an urban setting. Participants included a sample of 121 junior high and high school students (M = 15 years; range = 13–16 years; 60 males, 61 females) within high-crime neighborhoods. Consistent with our hypotheses, community violence and fam- ily violence were associated with PTS symptoms and school functioning problems. Our data suggest that community and family violence were indirectly related to school func- tioning problems through PTS symptoms. Findings from this study demonstrate that PTS symptoms potentially mediate the relationship between violence exposure and school functioning problems across two settings (community and home). Future research should further examine protective factors that can prevent youth violence exposure as well as negative outcomes related to violence

Adverse childhood experiences, support, and the perception of ability to work in adults with disability

Objective To examine the impact of adverse childhood experiences (ACEs) and support on self-reported work inability of adults reporting disability. Participants Adults (ages 18–64) who participated in the Behavioral Risk Factor Surveillance System in 2009 or 2010 and who reported having a disability (n = 13,009). Design and Main Outcome Measures The study used a retrospective cohort design with work inability as the main outcome. ACE categories included abuse (sexual, physical, emotional) and family dysfunction (domestic violence, incarceration, mental illness, substance abuse, divorce). Support included functional (perceived emotional/social support) and structural (living with another adult) support. Logistic regression was used to adjust for potential confounders (age, sex and race) and to evaluate whether there was an independent effect of ACEs on work inability after adding other important predictors (support, education, health) to the model. Results ACEs were highly prevalent with almost 75% of the sample reporting at least one ACE category and over 25% having a high ACE burden (4 or more categories). ACEs were strongly associated with functional support. Participants experiencing a high ACE burden had a higher adjusted odds ratio (OR) [95% confidence interval] of 1.9 [1.5–2.4] of work inability (reference: zero ACEs). Good functional support (adjusted OR 0.52 [0.42–0.63]) and structural support (adjusted OR 0.48 [0.41–0.56]) were protective against work inability. After adding education and health to the model, ACEs no longer appeared to have an independent effect. Structural support remained highly protective, but functional support only appeared to be protective in those with good physical health. Conclusions ACEs are highly prevalent in working-age US adults with a disability, particularly young adults. ACEs are associated with decreased support, lower educational attainment and worse adult health. Health care providers are encouraged to screen for ACEs. Addressing the effects of ACEs on health and support, in addition to education and retraining, may increase ability to work in those with a disability

Children’s Postdisaster Trajectories of PTS Symptoms: Predicting Chronic Distress

There are no studies of the distinct trajectories of children’s psychological distress over the first year after a destructive natural disaster and the determinants of these trajectories

Children’s Postdisaster Trajectories of PTS Symptoms: Predicting Chronic Distress

BACKGROUND: There are no studies of the distinct trajectories of children’s psychological distress over the first year after a destructive natural disaster and the determinants of these trajectories. OBJECTIVE: We examined these issues using an existing dataset of children exposed to Hurricane Andrew, one of the most devastating natural disasters in US history. METHODS: At 3-months postdisaster, 568 children (55 % girls; grades 3–5) residing in areas most directly affected by the hurricane completed measures of hurricane exposure and stressors, social support, coping, and general anxiety. Children also reported major life events occurring since the hurricane (at 7-months) and posttraumatic stress (PTS) symptoms at 3-, 7-, and 10-months postdisaster. RESULTS: Latent growth mixture modeling identified three trajectories of PTS reactions: resilient (37 %), recovering (43 %), and chronic distress (20 %). Predictors of the trajectories were examined. Odds ratios indicated that, compared to the resilient trajectory, girls were more likely to be in the recovering and chronically distressed trajectories, as were children reporting higher anxiety and greater use of coping strategies that reflected poor emotion regulation. Compared to the recovering trajectory, children in the chronically distressed trajectory had greater odds of reporting high anxiety, less social support, more intervening life events, and greater use of poor emotion regulation strategies. CONCLUSIONS: Hurricane exposure may be less effective in identifying children who develop chronic postdisaster distress than other child (anxiety, coping) and contextual variables (social support, life events). Effective screening after disasters is critical for identifying youth most in need of limited clinical resources

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

Genomic sequencing has driven precision-based oncology therapy; however, the genetic drivers of many malignancies remain unknown or non-targetable, so alternative approaches to the identification of therapeutic leads are necessary. Ependymomas are chemotherapy-resistant brain tumours, which, despite genomic sequencing, lack effective molecular targets. Intracranial ependymomas are segregated on the basis of anatomical location (supratentorial region or posterior fossa) and further divided into distinct molecular subgroups that reflect differences in the age of onset, gender predominance and response to therapy1,2,3. The most common and aggressive subgroup, posterior fossa ependymoma group A (PF-EPN-A), occurs in young children and appears to lack recurrent somatic mutations2. Conversely, posterior fossa ependymoma group B (PF-EPN-B) tumours display frequent large-scale copy number gains and losses but have favourable clinical outcomes1,3. More than 70% of supratentorial ependymomas are defined by highly recurrent gene fusions in the NF-κB subunit gene RELA (ST-EPN-RELA), and a smaller number involve fusion of the gene encoding the transcriptional activator YAP1 (ST-EPN-YAP1)1,3,4. Subependymomas, a distinct histologic variant, can also be found within the supratetorial and posterior fossa compartments, and account for the majority of tumours in the molecular subgroups ST-EPN-SE and PF-EPN-SE. Here we describe mapping of active chromatin landscapes in 42 primary ependymomas in two non-overlapping primary ependymoma cohorts, with the goal of identifying essential super-enhancer-associated genes on which tumour cells depend. Enhancer regions revealed putative oncogenes, molecular targets and pathways; inhibition of these targets with small molecule inhibitors or short hairpin RNA diminished the proliferation of patient-derived neurospheres and increased survival in mouse models of ependymomas. Through profiling of transcriptional enhancers, our study provides a framework for target and drug discovery in other cancers that lack known genetic drivers and are therefore difficult to treat.This work was supported by an Alex's Lemonade Stand Young Investigator Award (S.C.M.), The CIHR Banting Fellowship (S.C.M.), The Cancer Prevention Research Institute of Texas (S.C.M., RR170023), Sibylle Assmus Award for Neurooncology (K.W.P.), the DKFZ-MOST (Ministry of Science, Technology & Space, Israel) program in cancer research (H.W.), James S. McDonnell Foundation (J.N.R.) and NIH grants: CA154130 (J.N.R.), R01 CA169117 (J.N.R.), R01 CA171652 (J.N.R.), R01 NS087913 (J.N.R.) and R01 NS089272 (J.N.R.). R.C.G. is supported by NIH grants T32GM00725 and F30CA217065. M.D.T. is supported by The Garron Family Chair in Childhood Cancer Research, and grants from the Pediatric Brain Tumour Foundation, Grand Challenge Award from CureSearch for Children’s Cancer, the National Institutes of Health (R01CA148699, R01CA159859), The Terry Fox Research Institute and Brainchild. M.D.T. is also supported by a Stand Up To Cancer St. Baldrick’s Pediatric Dream Team Translational Research Grant (SU2C-AACR-DT1113)