4,512 research outputs found

    Octave bandwidth hybrid-coupled microstrip diplexer for a broadband radio astronomy receiver

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    A new octave bandwidth high selectivity compact microstrip diplexer working in the band from 10 to 20 GHz is presented, intended to be a part of an electro-optical interferometer covering the whole frequency band. The circuit is based on the combination of hybrid couplers and bandpass filters both on the microstrip technology. The diplexer provides two output frequency bands which cover the 10–14 GHz (relative bandwidth of 33%) and the 16–20 GHz (relative bandwidth of 22%) ranges, respectively, with a stop band in between from 14 to 16 GHz. Measured results show a insertion loss level of 3.3 dB for both output bands and high selectivity performance, exhibiting a rejection level between output bands higher than 20 dB and return loss better than 10 dB in all ports.This work has been funded by the Spanish Ministry of Economy, Industry and Competitiveness under Grant No. ESP2015-70646-C2-2-R

    Esophagogastric dissociation versus fundoplication: Which is best for severely neurologically impaired children?

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    Purpose: Neurologically impaired children (NIC) often have swallowing difficulties, severe gastroesophageal reflux, recurrent respiratory infections, and malnutrition. Bianchi pro posed esophagogastric dissociation (EGD) as an alternative to fundoplication and gastrostomy. The authors compared these 2 approaches.Methods: Twenty-nine consecutive symptomatic NIC refractory to medical therapy were enrolled in a prospective study and divided into 2 groups: A (n = 12), NIC who underwent fundoplication and gastrostomy; B (n = 14), NIC who underwent EGD. Three were excluded because of previous fundoplication, Anthropometric (percentage of the 50th percentile/ age of healthy children) and biochemical parameters, respiratory infections per year, hospitalization (days per year), feeding time (minutes), and "quality of life" (parental psychological questionnaire, range 0 to 60), were analyzed (t test and Mann-Whitney test) preoperatively and 1 year postoperatively. Complications were recorded.Results: Compared with group A, group B presented a statistically significant increase of all anthropometric and nearly all biochemical parameters with a statistical difference in terms of respiratory infections, hospital stay, feeding time, and psychological questionnaire. In group A, 2 bowel obstructions, 1 tight fundoplication, 1 dumping syndrome, and 3 failures of fundoplication occurred. Group B presented 1 anastomotic stricture, 1 paraesophageal hernia, and 1 bowel obstruction.Conclusions: Compared with fundoplication and gastrostomy, EGD offered better nutritional rehabilitation, reduction in respiratory infections, and improved quality of life. EGD can be rightfully chosen as a primary procedure. J Pediatr Surg 36:677-680. Copyright (C) 2001 by W.B. Saunders Company

    Nasal cellularity in 183 unselected schoolchildren aged 9 to 11 years

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    Although rhinitis is extremely frequent in children, methods for assessing the severity of nasal inflammation produce results with wide variability and hence weak clinical significance. We designed this epidemiologic investigation to define the clinical usefulness of assessing nasal cellularity in children

    POLÍTICA Y COMPORTAMIENTO SALARIAL EN LAS UNIVERSIDADES VENEZOLANAS 1985-2006

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    Este trabajo tiene como objetivo principal analizar las políticas salariales y el comportamiento del salario en las Universidades nacionales en Venezuela para el período 1985-2006. El enfoque teórico se fundamenta en las categorías de análisis de la Organización Internacional del Trabajo (OIT), Los acuerdos OPSU-CNU, Legislación del Trabajo, y Actas Convenios. La estrategia metodológica es de tipo descriptiva. La información se procesó con el programa estadístico SPSS 16.0 en español. Se buscó explicación de los efectos que tienen los indicadores económicos: Inflación y tipo de cambio tienen sobre el salario así la comparación en referencia a la canasta básica y alimentaria. También se comparó en términos relativos del equivalente de las normas de homologación con el tipo de cambio y el salario mínimo tanto real como nominal. Los resultados de esta investigación: Salario real desmejorado, relación inversa del salario en términos del tipo de cambio, la brecha es cada vez más estrecha con el salario mínimo de subsistencia y los sueldos de los profesores, efectos perversos de los indicadores económicos, posición flexible de los gremios frente al gobierno con escaso liderazgo de la dirigencia y con discurso poco motivador de las masas laborales, violación de los principios fundamentales del derecho al no cumplir con las normas de homologación, escaso poder adquisitivo de los docentes para obtener la canasta básica y la canasta normativa de alimentos, casi nula la capacidad de ahorro, llegando a la conclusión que si ha disminuido la calidad de vida del profesor universitario durante el periodo 1985-2006

    Shotgun Proteomics of Isolated Urinary Extracellular Vesicles for Investigating Respiratory Impedance in Healthy Preschoolers

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    Urine proteomic applications in children suggested their potential in discriminating between healthy subjects from those with respiratory diseases. The aim of the current study was to combine protein fractionation, by urinary extracellular vesicle isolation, and proteomics analysis in order to establish whether different patterns of respiratory impedance in healthy preschoolers can be characterized from a protein fingerprint. Twenty-one 3-5-yr-old healthy children, representative of 66 recruited subjects, were selected: 12 late preterm (LP) and 9 full-term (T) born. Children underwent measurement of respiratory impedance through Forced Oscillation Technique (FOT) and no significant differences between LP and T were found. Unbiased clustering, based on proteomic signatures, stratified three groups of children (A, B, C) with significantly different patterns of respiratory impedance, which was slightly worse in group A than in groups B and C. Six proteins (Tripeptidyl peptidase I (TPP1), Cubilin (CUBN), SerpinA4, SerpinF1, Thy-1 membrane glycoprotein (THY1) and Angiopoietin-related protein 2 (ANGPTL2)) were identified in order to type the membership of subjects to the three groups. The differential levels of the six proteins in groups A, B and C suggest that proteomic-based profiles of urinary fractionated exosomes could represent a link between respiratory impedance and underlying biological profiles in healthy preschool children

    Efficacy and Safety of Prophylactic Vaccines against Cervical HPV Infection and Diseases among Women: A Systematic Review & Meta-Analysis

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    <p>Abstract</p> <p>Background</p> <p>We conducted a systematic review and meta-analysis to assess efficacy and safety of prophylactic HPV vaccines against cervical cancer precursor events in women.</p> <p>Methods</p> <p>Randomized-controlled trials of HPV vaccines were identified from MEDLINE, Cochrane Central Register of Controlled Trials, conference abstracts and references of identified studies, and assessed by two independent reviewers. Efficacy data were synthesized using fixed-effect models, and evaluated for heterogeneity using I<sup>2 </sup>statistic.</p> <p>Results</p> <p>Seven unique trials enrolling 44,142 females were included. The fixed-effect Relative Risk (RR) and 95% confidence intervals were 0.04 (0.01-0.11) and 0.10 (0.03-0.38) for HPV-16 and HPV 18-related CIN2+ in the per-protocol populations (PPP). The corresponding RR was 0.47 (0.36-0.61) and 0.16 (0.08-0.34) in the intention-to-treat populations (ITT). Efficacy against CIN1+ was similar in scale in favor of vaccine. Overall vaccines were highly efficacious against 6-month persistent infection with HPV 16 and 18, both in the PPP cohort (RR: 0.06 [0.04-0.09] and 0.05 [0.03-0.09], respectively), and the ITT cohorts (RR: 0.15 [0.10-0.23] and 0.24 [0.14-0.42], respectively). There was limited prophylactic effect against CIN2+ and 6-month persistent infections associated with non-vaccine oncogenic HPV types. The risk of serious adverse events (RR: 1.00, 0.91-1.09) or vaccine-related serious adverse events (RR: 1.82; 0.79-4.20) did not differ significantly between vaccine and control groups. Data on abnormal pregnancy outcomes were underreported.</p> <p>Conclusions</p> <p>Prophylactic HPV vaccines are safe, well tolerated, and highly efficacious in preventing persistent infections and cervical diseases associated with vaccine-HPV types among young females. However, long-term efficacy and safety needs to be addressed in future trials.</p

    The Intrinsic Fundamental Group of a Linear Category

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    We provide an intrinsic definition of the fundamental group of a linear category over a ring as the automorphism group of the fibre functor on Galois coverings. If the universal covering exists, we prove that this group is isomorphic to the Galois group of the universal covering. The grading deduced from a Galois covering enables us to describe the canonical monomorphism from its automorphism group to the first Hochschild-Mitchell cohomology vector space.Comment: Final version, to appear in Algebras and Representation Theor

    Interdigitated ring electrodes: Theory and experiment

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    The oxidation of potassium ferrocyanide, K_4Fe(CN)_6, in aqueous solution under fully supported conditions is carried out at interdigitated band and ring electrode arrays, and compared to theoretical models developed to simulate the processes. Simulated data is found to fit well with experimental results using literature values of diffusion coefficients for Fe(CN)_6^(4-) and Fe(CN)_6^(3-). The theoretical models are used to compare responses from interdigitated band and ring arrays, and the size of ring array required to approximate the response to a linear band array is investigated. An equation is developed for the radius of ring required for a pair of electrodes in a ring array to give a result with 5% of a pair of electrodes in a band array. This equation is found to be independent of the scan rate used over six orders of magnitude
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