10,911 research outputs found
Z Flux-Line Lattices and Self-Dual Equations in the Standard Model
We derive gauge covariant self-dual equations for the
theory of electro-weak interactions and show that they admit solutions
describing a periodic lattice of Z-strings.} \newpageComment: 10 pages, IC/94/65, INFN-NA-IV-5/9
Aharonov-Bohm Scattering, Contact Interactions and Scale Invariance
We perform a perturbative analysis of the Aharonov-Bohm problem to one loop
in a field-theoretic formulation, and show that contact interactions are
necessary for renormalizability. In general, the classical scale invariance of
this problem is broken quantum mechanically. There exists however a critical
point for which this anomaly disappears.Comment: 9 pages, TEX, CTP#218
Differential Regularization of a Non-relativistic Anyon Model
Differential regularization is applied to a field theory of a
non-relativistic charged boson field with
self-interaction and coupling to a statistics-changing Chern-Simons
gauge field. Renormalized configuration-space amplitudes for all diagrams
contributing to the 4-point function, which
is the only primitively divergent Green's function, are obtained up to 3-loop
order. The renormalization group equations are explicitly checked, and the
scheme dependence of the -function is investigated. If the
renormalization scheme is fixed to agree with a previous 1-loop calculation,
the 2- and 3-loop contributions to vanish, and
itself vanishes when the ``self-dual'' condition relating
to the gauge coupling is imposed.Comment: 22 pages in ReVTEX (with a plaintext PostScript figure appended at
end), MIT CTP #221
Depinning and dynamics of AC driven vortex lattices in random media
We study the different dynamical regimes of a vortex lattice driven by AC
forces in the presence of random pinning via numerical simulations. The
behaviour of the different observables is charaterized as a function of the
applied force amplitude for different frequencies. We discuss the
inconveniences of using the mean velocity to identify the depinnig transition
and we show that instead, the mean quadratic displacement of the lattice is the
relevant magnitude to characterize different AC regimes. We discuss how the
results depend on the initial configuration and we identify new hysteretic
effects which are absent in the DC driven systems.Comment: 6 pages, 4 figure
Fundamental Limits of Cooperation
Cooperation is viewed as a key ingredient for interference management in
wireless systems. This paper shows that cooperation has fundamental
limitations. The main result is that even full cooperation between transmitters
cannot in general change an interference-limited network to a noise-limited
network. The key idea is that there exists a spectral efficiency upper bound
that is independent of the transmit power. First, a spectral efficiency upper
bound is established for systems that rely on pilot-assisted channel
estimation; in this framework, cooperation is shown to be possible only within
clusters of limited size, which are subject to out-of-cluster interference
whose power scales with that of the in-cluster signals. Second, an upper bound
is also shown to exist when cooperation is through noncoherent communication;
thus, the spectral efficiency limitation is not a by-product of the reliance on
pilot-assisted channel estimation. Consequently, existing literature that
routinely assumes the high-power spectral efficiency scales with the log of the
transmit power provides only a partial characterization. The complete
characterization proposed in this paper subdivides the high-power regime into a
degrees-of-freedom regime, where the scaling with the log of the transmit power
holds approximately, and a saturation regime, where the spectral efficiency
hits a ceiling that is independent of the power. Using a cellular system as an
example, it is demonstrated that the spectral efficiency saturates at power
levels of operational relevance.Comment: 27 page
Self-dual Chern-Simons solitons in noncommutative space
We construct exact soliton solutions to the Chern-Simons-Higgs system in
noncommutative space, for non-relativistic and relativistic models. In both
cases we find regular vortex-like solutions to the BPS equations which approach
the ordinary selfdual non-topological and topological solitons when the
noncommutative parameter goes to zero.Comment: 15 pages, 4 figure
On Symmetry Non-Restoration at High Temperature
We study the effect of next-to-leading order contributions on the phenomenon
of symmetry non-restoration at high temperature in an
model.Comment: 8 pages. Two figures in a separate fil
Estimating the cost-effectiveness of fluticasone propionate for treating chronic obstructive pulmonary disease in the presence of missing data
Objectives: To explore the cost-effectiveness of fluticasone propionate (FP) for the treatment of chronic obstructive pulmonary disease (COPD), we estimated costs and qualityadjusted life-years (QALYs) over 3 years, based on an economic appraisal of a previously reported clinical trial
(Inhaled Steroids in Obstructive Lung Disease in Europe [ISOLDE]).
Methods: Seven hundred forty-two patients enrolled in the ISOLDE trial who received either FP or placebo had data available on health-care costs and quality of life over the period of the study. The SF-36-based utility scores for quality
of life were used to calculate QALYs. A combined imputation and bootstrapping procedure was employed to handle missing data and to estimate statistical uncertainty in the estimated
cumulative costs and QALYs over the study period.
The imputation approach was based on propensity scoring and nesting this approach within the bootstrap ensured that multiple imputations were performed such that statistical estimates included imputation uncertainty.
Results: Complete data were available on mortality within the follow-up period of the study and a nonsignificant trend toward improved survival of 0.06 (95% confidence interval [CI] –0.01 to 0.15) life-years was observed. In an analysis based on a propensity scoring approach to missing data we estimated the incremental costs of FP versus placebo to be £1021 (95% CI £619–1338) with an additional effect of 0.11 QALYs (CI 0.04–0.20). Cost-effectiveness estimates
for the within-trial period of £17,700 per life-year gained (£6900 to ∞) and £9500 per QALY gained (CI £4300–26,500) were generated that include uncertainty due to the imputation process. An alternative imputation approach did
not materially affect these estimates.
Conclusions: Previous analyses of the ISOLDE study
showed significant improvement on disease-specific health status measures and a trend toward a survival advantage for treatment with FP. This analysis shows that joint considerations
of quality of life and survival result in a substantial increase in QALYs favoring treatment with FP. Based on these data, the inhaled corticosteroid FP appears costeffective for the treatment of COPD. Confirmation or refutation
of this result may be achieved once the Towards a
Revolution in COPD Health (TORCH) study reports, a large randomized controlled trial powered to detect mortality changes associated with the use of FP alone, or in combination with salmeterol, which is also collecting resource use and utility data suitable for estimating cost-effectiveness
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