Combining Physical galaxy models with radio observations to constrain the SFRs of high-z dusty star forming galaxies

We complement our previous analysis of a sample of z~1-2 luminous and ultra-luminous infrared galaxies ((U)LIRGs), by adding deep VLA radio observations at 1.4 GHz to a large data-set from the far-UV to the sub-mm, including Spitzer and Herschel data. Given the relatively small number of (U)LIRGs in our sample with high S/N radio data, and to extend our study to a different family of galaxies, we also include 6 well sampled near IR-selected BzK galaxies at z~1.5. From our analysis based on the radiative transfer spectral synthesis code GRASIL, we find that, while the IR luminosity may be a biased tracer of the star formation rate (SFR) depending on the age of stars dominating the dust heating, the inclusion of the radio flux offers significantly tighter constraints on SFR. Our predicted SFRs are in good agreement with the estimates based on rest-frame radio luminosity and the Bell (2003) calibration. The extensive spectro-photometric coverage of our sample allows us to set important constraints on the SF history of individual objects. For essentially all galaxies we find evidence for a rather continuous SFR and a peak epoch of SF preceding that of the observation by a few Gyrs. This seems to correspond to a formation redshift of z~5-6. We finally show that our physical analysis may affect the interpretation of the SFR-M* diagram, by possibly shifting, with respect to previous works, the position of the most dust obscured objects to higher M* and lower SFRs.Comment: 26 pages, 15 figures, 3 tables, accepted for publication in MNRAS on Dec. 4th, 201

Virtual volatility

We introduce the concept of virtual volatility. This simple but new measure shows how to quantify the uncertainty in the forecast of the drift component of a random walk. The virtual volatility also is a useful tool in understanding the stochastic process for a given portfolio. In particular, and as an example, we were able to identify mean reversion effect in our portfolio. Finally, we briefly discuss the potential practical effect of the virtual volatility on an investor asset allocation strategy.Comment: 15 pages, 2 figures, elsart.cls, Accepted to Physica A. Added few comments that clarify data used for empirical wor

Co-silencing of human Bub3 and dynein highlights an antagonistic relationship in regulating kinetochore-microtubule attachments

We previously reported that the spindle assembly checkpoint protein Bub3 is involved in regulating kinetochore-microtubule (KT-MT) attachments. Also, Bub3 was reported to interact with the microtubule motor protein dynein. Here we examined how this interaction contributes to KT-MT attachments. Depletion of Bub3 or dynein induced misaligned chromosomes, consistent with their role in KT-MT attachments. Unexpectedly, co-silencing of both proteins partially suppressed the misalignment phenotype and restored chromosome congression. Consistent with these observations, KT-MT attachments in co-depleted cells were stable, able to drive chromosome congression, and produce inter-and intra-kinetochore stretch, indicating they are functional. We suggest that a mutual antagonism exists between Bub3 and dynein to ensure optimal KT-MT attachments. (C) 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.CESPU [02-GCQF-CICS-2011N]; FCT - Fundacao para a Ciencia e a Tecnologia [CEQUIMED-PEst-OE/SAU/UI4040/2014]; FCT [SFRH/BD/90744/2012]info:eu-repo/semantics/publishedVersio

A role for antizyme inhibitor in cell proliferation

Acknowledgments We thank Ewa Dahlberg and Lena Thiman for expert technical help with cell culturing and HPLC, respectively. The authors acknowledge financial support from the Portuguese Foundation for Science and Technology—SFRH/BD/46364/2008 (PhD fellowship to T. M. S.), the Gunnar Nilssons Cancer Foundation, the Mrs Berta Kamprad Foundation and the Per-Eric and Ulla Schyberg Foundation. Heather Wallace was supported by a visiting scholarship from Lund University. We are grateful for the generous supply of AzI antibody and pcDNA3.1-AzI from Dr. Senya Matsufuji and Dr. Yasuku Murakami (Tokyo, Japan), and Dr. Leif Andersson (Helsinki, Finland), respectively.Peer reviewedPublisher PD

Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)

As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2’-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and -carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (inìg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity

Cryptanalysis of two chaotic encryption schemes based on circular bit shift and XOR operations

Recently two encryption schemes were proposed by combining circular bit shift and XOR operations, under the control of a pseudorandom bit sequence (PRBS) generated from a chaotic system. This paper studies the security of these two encryption schemes and reports the following findings: 1) there exist some security defects in both schemes; 2) the underlying chaotic PRBS can be reconstructed as an equivalent key by using only two chosen plaintexts; 3) most elements in the underlying chaotic PRBS can be obtained by a differential known-plaintext attack using only two known plaintexts. Experimental results are given to demonstrate the feasibility of the proposed attack.Comment: 17 pages, 8 figure

The Spin-Statistics Connection in Quantum Gravity

It is well-known that is spite of sharing some properties with conventional particles, topological geons in general violate the spin-statistics theorem. On the other hand, it is generally believed that in quantum gravity theories allowing for topology change, using pair creation and annihilation of geons, one should be able to recover this theorem. In this paper, we take an alternative route, and use an algebraic formalism developed in previous work. We give a description of topological geons where an algebra of "observables" is identified and quantized. Different irreducible representations of this algebra correspond to different kinds of geons, and are labeled by a non-abelian "charge" and "magnetic flux". We then find that the usual spin-statistics theorem is indeed violated, but a new spin-statistics relation arises, when we assume that the fluxes are superselected. This assumption can be proved if all observables are local, as is generally the case in physical theories. Finally, we also show how our approach fits into conventional formulations of quantum gravity.Comment: LaTeX file, 31 pages, 5 figure