176 research outputs found

    Deep seabed mining: A note on some potentials and risks to the sustainable mineral extraction from the oceans

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    The rapidly increasing global populations and socio-economic development in the Global South have resulted in rising demand for natural resources. There are many plans for harvesting natural resources from the ocean floor, especially rare metals and minerals. However, if proper care is not taken, there is substantial potential for long-lasting and even irreversible physical and environmental impacts on the deep-sea ecosystems, including on biodiversity and ecosystem functioning. This paper reviews the literature on some potentials and risks to deep seabed mining (DSM), outlining its legal aspects and environmental impacts. It presents two case studies that describe the environmental risks related to this exploitative process. They include significant disturbance of the seabed, light and noise pollution, the creation of plumes, and negative impacts on the surface, benthic, and meso-and bathypelagic zones. The study suggests some of the issues interested companies should consider in preventing the potential physical and environmental damages DSM may cause. Sustainable mining and the use of minerals are vital in meeting various industrial demands

    Transient poverty in a sustainable development context

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    Transient poverty (TP) is a phenomenon that, by its characterisation, references a condition that may not necessarily be permanent. Its occurrence may result from an external shock, such as a severe weather-related event or geographic, national, or global impact on the economy, such as a hurricane, financial crisis, or as most recently, a pandemic. The defining aspects of TP and the needs of those pushed into TP offer an opportunity to address one aspect of poverty, which is of significance given both the disproportionate vulnerability of the poor to external shocks as well as the prohibitive effect of poverty on establishing resilience. Unfortunately, TP is not often assessed and is routinely combined and categorised as ‘poverty’, eliminating an opportunity to address unique aspects of TP and establish policies that may be beneficial to the sub-group. This paper provides a bibliometric evaluation of TP specific to the sustainable development literature, highlighting the research gap and providing a rationale for active research on the social phenomenon regarding the Sustainable Development Goals (SDG) in general and specifically SDG 1: No poverty. There are three key findings relevant to sustainability. Firstly, there seems to be a disconnection between TP and the sustainable development theory, particularly in a multidisciplinary discussion. Secondly, human action in degrading ecosystems strongly influences TP and exacerbates overall poverty levels. Finally, efforts to tackle transient poverty need to consider issues such as gender, education, health, and political aspects. Based on the findings, items for future research are also presented

    Influence of Exposure History on the Immunology and Development of Resistance to Human Schistosomiasis Mansoni

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    Schistosomiasis is a parasitic blood fluke infection of 200 million people worldwide. We have shown that humans can acquire immunity to reinfection after repeated exposures and cures with the drug praziquantel. The increase in resistance to reinfection was associated with an increase in schistosome-specific IgE. The ability to develop resistance and the rate at which resistance was acquired varied greatly in two cohorts of men within close geographic proximity and with similar occupational exposures to schistosomes. These differences are likely attributable to differences in history of exposure to Schistosoma mansoni infection and immunologic status at baseline, with those acquiring immunity faster having lifelong S. mansoni exposure and immunologic evidence of chronic S. mansoni infection. As many conflicting results have been reported in the literature regarding immunologic parameters associated with the development of resistance to schistosome infection, exposure history and prior immune status should be considered in the design of future immuno-epidemiologic studies

    How Habitat Change and Rainfall Affect Dung Beetle Diversity in Caatinga, a Brazilian Semi-Arid Ecosystem

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    The aim of the present study was to evaluate how dung beetle communities respond to both environment and rainfall in the Caatinga, a semi-arid ecosystem in northeastern Brazil. The communities were sampled monthly from May 2006 to April 2007 using pitfall traps baited with human feces in two environments denominated “land use area” and “undisturbed area.” Abundance and species richness were compared between the two environments and two seasons (dry and wet season) using a generalized linear model with a Poisson error distribution. Diversity was compared between the two environments (land use area and undisturbed area) and seasons (dry and wet) using the Two-Way ANOVA test. Non-metric multidimensional scaling was performed on the resemblance matrix of Bray-Curtis distances (with 1000 random restarts) to determine whether disturbance affected the abundance and species composition of the dung beetle communities. Spearman's correlation coefficient was used to determine whether rainfall was correlated with abundance and species richness. A total of 1097 specimens belonging to 13 species were collected. The most abundant and frequent species was Dichotomius geminatus Arrow (Coleoptera: Scarabaeidae). The environment exerted an influence over abundance. Abundance and diversity were affected by season, with an increase in abundance at the beginning of the wet season. The correlation coefficient values were high and significant for abundance and species richness, which were both correlated to rainfall. In conclusion, the restriction of species to some environments demonstrates the need to preserve these areas in order to avoid possible local extinction. Therefore, in extremely seasonable environments, such as the Caatinga, seasonal variation strongly affects dung beetle communities

    The Interaction Properties of the Human Rab GTPase Family – A Comparative Analysis Reveals Determinants of Molecular Binding Selectivity

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    Rab GTPases constitute the largest subfamily of the Ras protein superfamily. Rab proteins regulate organelle biogenesis and transport, and display distinct binding preferences for effector and activator proteins, many of which have not been elucidated yet. The underlying molecular recognition motifs, binding partner preferences and selectivities are not well understood.Comparative analysis of the amino acid sequences and the three-dimensional electrostatic and hydrophobic molecular interaction fields of 62 human Rab proteins revealed a wide range of binding properties with large differences between some Rab proteins. This analysis assists the functional annotation of Rab proteins 12, 14, 26, 37 and 41 and provided an explanation for the shared function of Rab3 and 27. Rab7a and 7b have very different electrostatic potentials, indicating that they may bind to different effector proteins and thus, exert different functions. The subfamily V Rab GTPases which are associated with endosome differ subtly in the interaction properties of their switch regions, and this may explain exchange factor specificity and exchange kinetics.We have analysed conservation of sequence and of molecular interaction fields to cluster and annotate the human Rab proteins. The analysis of three dimensional molecular interaction fields provides detailed insight that is not available from a sequence-based approach alone. Based on our results, we predict novel functions for some Rab proteins and provide insights into their divergent functions and the determinants of their binding partner selectivity

    An analysis of climate change and health hazards: results from an international study

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    Purpose: The interconnections between climate change and health are well studied. However, there is a perceived need for studies that examine how responses to health hazards (e.g. cardiovascular diseases, ozone layer effects, allergens, mental health and vector-borne diseases) may assist in reducing their impacts. The purpose of this paper is to review the evidence on health responses to climate hazards and list some measures to address them. Design/methodology/approach: A mixed literature review, bibliometric analysis and an original online survey were undertaken on 140 participants from 55 countries spread across all geographical regions. Findings: The bibliometric analysis identified that most climate-related health hazards are associated with extreme weather events. However, only one-third of the investigated papers specifically analysed the connections between climate change and health hazards, revealing a thematic gap. Also, although Africa is highly affected by climate change, only 5% of the assessed studies focused on this continent. Many respondents to the survey indicated “heat distress” as a significant vulnerability. The survey also identified social determinants relevant to climate-induced health vulnerabilities, such as socioeconomic and environmental factors, infrastructure and pre-existing health conditions. Most respondents agree that policies and regulations are the most effective adaptation tools to address the public health hazards triggered by climate change. This paper presents some suggestions for optimising public health responses to health hazards associated with climate change, such as the inclusion of climate-related components in public health policies, setting up monitoring systems to assess the extent to which specific climate events may pose a health threat, establishing plans to cope with the health implications of heatwaves, increased measures to protect vulnerable groups and education and awareness-raising initiatives to reduce the overall vulnerability of the population to climate-related health hazards. These measures may assist the ongoing global efforts to understand better – and cope with – the impacts of climate change on health. Originality/value: The combination of a literature review, bibliometric analysis and an original world survey identified and presented a wide range of responses

    Are ant assemblages of Brazilian veredas characterised by location or habitat type?

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    Wetland areas in the Brazilian Cerrado, known as “veredas”, represent ecosystems formed on sandy soils with high concentrations of peat, and are responsible for the recharge of aquiferous reservoirs. They are currently under threat by various human activities, most notably the clearing of vegetation for Eucalyptus plantations. Despite their ecological importance and high conservation value, little is known about the actual effects of human disturbance on the animal community. To assess how habitat within different veredas, and plantations surrounding them affect ant assemblages, we selected four independent vereda locations, two being impacted by Eucalyptus monoculture (one younger and one mature plantation) and two controls, where the wetland was surrounded by cerrado vegetation. Ant sampling was conducted in May 2010 (dry season) using three complementary methods, namely baits, pitfall traps, and hand collection, in the wetland and in the surrounding habitats. A total of 7,575 ants were sampled, belonging to seven subfamilies, 32 genera and 124 species.Ant species richness and abundance did not differ between vereda locations, but did between the habitats. When impacted by the monoculture, ant species richness and abundance decreased in wetlands, but were less affected in the cerrado habitat. Ant species composition differed between the three habitats and between vereda locations. Eucalyptus plantations had an ant species composition defined by high dominance of Pheidole sp. and Solenopsis invicta, while natural habitats were defined by Camponotus and Crematogaster species. Atta sexdens was strictly confined to native habitats of non-impacted “veredas”. Eucalyptus monocultures require high quantities of water in the early stages, which may have caused a decrease in groundwater level in the wetland, allowing hypogeic ants such as Labidus praedator to colonise this habitat

    IL-10 Blocks the Development of Resistance to Re-Infection with Schistosoma mansoni

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    Despite effective chemotherapy to treat schistosome infections, re-infection rates are extremely high. Resistance to reinfection can develop, however it typically takes several years following numerous rounds of treatment and re-infection, and often develops in only a small cohort of individuals. Using a well-established and highly permissive mouse model, we investigated whether immunoregulatory mechanisms influence the development of resistance. Following Praziquantel (PZQ) treatment of S. mansoni infected mice we observed a significant and mixed anti-worm response, characterized by Th1, Th2 and Th17 responses. Despite the elevated anti-worm response in PBMC's, liver, spleen and mesenteric lymph nodes, this did not confer any protection from a secondary challenge infection. Because a significant increase in IL-10-producing CD4+CD44+CD25+GITR+ lymphocytes was observed, we hypothesised that IL-10 was obstructing the development of resistance. Blockade of IL-10 combined with PZQ treatment afforded a greater than 50% reduction in parasite establishment during reinfection, compared to PZQ treatment alone, indicating that IL-10 obstructs the development of acquired resistance. Markedly enhanced Th1, Th2 and Th17 responses, worm-specific IgG1, IgG2b and IgE and circulating eosinophils characterized the protection. This study demonstrates that blocking IL-10 signalling during PZQ treatment can facilitate the development of protective immunity and provide a highly effective strategy to protect against reinfection with S. mansoni
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