352 research outputs found
Obsessive-Compulsive Disorder and Attachment
Introdução: A teoria da vinculação pretende
explicar de que forma as disposiçÔes biolĂłgicas e as experiĂȘncias precoces predispĂ”em o
indivĂduo Ă saĂșde mental ou Ă patologia.
Objetivos: Reportar um caso de Perturbação
Obsessivo-Compulsiva num jovem com padrão de vinculação ansiosa, realizando uma
revisão da literatura sobre a associação entre
as duas entidades.
MĂ©todos: Ă apresentado um caso clĂnico de
um jovem com Perturbação Obsessivo-Compulsiva com Perturbação de Ingestão Alimentar/Restritiva e de Ansiedade Generalizada
comórbidas. O Questionårio de Vinculação ao
Pai e Ă MĂŁe foi aplicado para avaliar o estilo de
vinculação. Uma anålise bibliogråfica sobre o
tema foi realizada, evidenciado a contribuição
dos processos de vinculação, a abordagem e o
tratamento.
Resultados: O Questionårio de Vinculação ao
Pai e à Mãe evidenciou uma vinculação ansiosa no jovem.
ConclusÔes: O presente caso pode ilustrar
como um padrão ansioso de vinculação poderå ter influenciado o subsequente desenvolvimento de psicopatologia. Uma abordagem
psicofarmacolĂłgica, a par da psicoterapĂȘutica
envolvendo doente e cuidadores, parece ser a
mais adequada tendo-se revelado eficaz neste
caso.info:eu-repo/semantics/publishedVersio
Atividade antimicrobiana de subfraçÔes padronizadas da planta Arrabidaea chica Verl.
Este estudo analisou o potencial terapĂȘutico de extratos e subfraçÔes padronizadas da planta amazĂŽnica Arrabidaea chica, visando seu uso tĂłpico como medicamento e eficĂĄcia comprovada em doenças cutĂąneas
Cyclotron resonant scattering feature simulations. I. Thermally averaged cyclotron scattering cross sections, mean free photon-path tables, and electron momentum sampling
Electron cyclotron resonant scattering features (CRSFs) are observed as
absorption-like lines in the spectra of X-ray pulsars. A significant fraction
of the computing time for Monte Carlo simulations of these quantum mechanical
features is spent on the calculation of the mean free path for each individual
photon before scattering, since it involves a complex numerical integration
over the scattering cross section and the (thermal) velocity distribution of
the scattering electrons.
We aim to numerically calculate interpolation tables which can be used in
CRSF simulations to sample the mean free path of the scattering photon and the
momentum of the scattering electron. The tables also contain all the
information required for sampling the scattering electron's final spin.
The tables were calculated using an adaptive Simpson integration scheme. The
energy and angle grids were refined until a prescribed accuracy is reached. The
tables are used by our simulation code to produce artificial CRSF spectra. The
electron momenta sampled during these simulations were analyzed and justified
using theoretically determined boundaries.
We present a complete set of tables suited for mean free path calculations of
Monte Carlo simulations of the cyclotron scattering process for conditions
expected in typical X-ray pulsar accretion columns (0.01<B/B_{crit}<=0.12,
where B_{crit}=4.413x10^{13} G and 3keV<=kT<15keV). The sampling of the tables
is chosen such that the results have an estimated relative error of at most
1/15 for all points in the grid. The tables are available online at
http://www.sternwarte.uni-erlangen.de/research/cyclo.Comment: A&A, in pres
X-ray emission from magnetized neutron star atmospheres at low mass accretion rates. I. Phase-averaged spectrum
Recent observations of X-ray pulsars at low luminosities allow, for the first
time, to compare theoretical models for the emission from highly magnetized
neutron star atmospheres at low mass accretion rates ( g s) with the broadband X-ray data. The purpose of this paper
is to investigate the spectral formation in the neutron star atmosphere at low
and to conduct a parameter study of physical properties of the
emitting region. We obtain the structure of the static atmosphere, assuming
that Coulomb collisions are the dominant deceleration process. The upper part
of the atmosphere is strongly heated by the braking plasma, reaching
temperatures of 30-40 keV, while its denser isothermal interior is much cooler
(~2 keV). We numerically solve the polarized radiative transfer in the
atmosphere with magnetic Compton scattering, free-free processes, and
non-thermal cyclotron emission due to possible collisional excitations of
electrons. The strongly polarized emitted spectrum has a double-hump shape that
is observed in low-luminosity X-ray pulsars. A low-energy "thermal" component
is dominated by extraordinary photons that can leave the atmosphere from deeper
layers due to their long mean free path at soft energies. We find that a
high-energy component is formed due to resonant Comptonization in the heated
non-isothermal part of the atmosphere even in the absence of collisional
excitations. The latter, however, affect the ratio of the two components. A
strong cyclotron line originates from the optically thin, uppermost zone. A fit
of the model to NuSTAR and Swift/XRT observations of GX 304-1 provides an
accurate description of the data with reasonable parameters. The model can thus
reproduce the characteristic double-hump spectrum observed in low-luminosity
X-ray pulsars and provides insights into spectral formation.Comment: 18 pages, 10 figures, A&A accepte
Braga 2027. European Capital of Culture Candidate City
Braga's final candidacy dossier for European Capital of Culture 202
Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1
PMCID: PMC3601088This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Body composition and body fat distribution are related to cardiac autonomic control in non-alcoholic fatty liver disease patients
BACKGROUND/OBJECTIVES: Heart rate recovery (HRR), a cardiac autonomic control marker, was shown to be related to body composition (BC), yet this was not tested in non-alcoholic fatty liver disease (NAFLD) patients. The aim of this study was to determine if, and to what extent, markers of BC and body fat (BF) distribution are related to cardiac autonomic control in NAFLD patients. SUBJECTS/METHODS: BC was assessed with dual-energy X-ray absorptiometry in 28 NAFLD patients (19 men, 51±13 years, and 9 women, 47±13 years). BF depots ratios were calculated to assess BF distribution. Subjectsâ HRR was recorded 1 (HRR1) and 2 min (HRR2) immediately after a maximum graded exercise test.
RESULTS: BC and BF distribution were related to HRR; particularly weight, trunk BF and trunk BF-to-appendicular BF ratio showed a negative relation with HRR1 (r 1â4 0.613, r 1â4 0.597 and r 1â4 0.547, respectively, Po0.01) and HRR2 (r 1â4 0.484, r 1â4 0.446, Po0.05, and r 1â4 0.590, Po0.01, respectively). Age seems to be related to both HRR1 and HRR2 except when controlled for BF distribution. The preferred model in multiple regression should include trunk BF-to-appendicular BF ratio and BF to predict HRR1 (r2 1â4 0.549; Po0.05), and trunk BF-to-appendicular BF ratio alone to predict HRR2 (r2 1â4 0.430; Po0.001).
CONCLUSIONS: BC and BF distribution were related to HRR in NAFLD patients. Trunk BF-to-appendicular BF ratio was the best independent predictor of HRR and therefore may be best related to cardiovascular increased risk, and possibly act as a mediator in age-related cardiac autonomic control variation.info:eu-repo/semantics/publishedVersio
Neural correlates of sexual cue reactivity in individuals with and without compulsive sexual behaviours
Although compulsive sexual behaviour (CSB) has been conceptualized as a "behavioural" addiction and common or overlapping neural circuits may govern the processing of natural and drug rewards, little is known regarding the responses to sexually explicit materials in individuals with and without CSB. Here, the processing of cues of varying sexual content was assessed in individuals with and without CSB, focusing on neural regions identified in prior studies of drug-cue reactivity. 19 CSB subjects and 19 healthy volunteers were assessed using functional MRI comparing sexually explicit videos with non-sexual exciting videos. Ratings of sexual desire and liking were obtained. Relative to healthy volunteers, CSB subjects had greater desire but similar liking scores in response to the sexually explicit videos. Exposure to sexually explicit cues in CSB compared to non-CSB subjects was associated with activation of the dorsal anterior cingulate, ventral striatum and amygdala. Functional connectivity of the dorsal anterior cingulate-ventral striatum-amygdala network was associated with subjective sexual desire (but not liking) to a greater degree in CSB relative to non-CSB subjects. The dissociation between desire or wanting and liking is consistent with theories of incentive motivation underlying CSB as in drug addictions. Neural differences in the processing of sexual-cue reactivity were identified in CSB subjects in regions previously implicated in drug-cue reactivity studies. The greater engagement of corticostriatal limbic circuitry in CSB following exposure to sexual cues suggests neural mechanisms underlying CSB and potential biological targets for interventions
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