12 research outputs found
Transkingdom Networks: A Systems Biology Approach to Identify Causal Members of Host-Microbiota Interactions
Full text linkImprovements in sequencing technologies and reduced experimental costs have
resulted in a vast number of studies generating high-throughput data. Although
the number of methods to analyze these "omics" data has also increased,
computational complexity and lack of documentation hinder researchers from
analyzing their high-throughput data to its true potential. In this chapter we
detail our data-driven, transkingdom network (TransNet) analysis protocol to
integrate and interrogate multi-omics data. This systems biology approach has
allowed us to successfully identify important causal relationships between
different taxonomic kingdoms (e.g. mammals and microbes) using diverse types of
data
Expression of CD40 ligand, interferon-gamma and Fas ligand genes in endomyocardial biopsies of human cardiac allografts: correlation with acute rejection
Full text linkThe effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation
Get PDFPossible Magnetic Background of the Metal-Insulator Transition in Two-Dimensional Correlated Electron System
No full textA single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
No full textAntibiotic-Induced Alterations in Gut Microbiota Are Associated with Changes in Glucose Metabolism in Healthy Mice
No full textThemis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection
No full textGenetic Heterogeneity of Self-Reported Ancestry Groups in an Admixed Brazilian Population
No full text
