ONDE ESTÃO OS EGRESSOS DO CURSO DE ADMINISTRAÇÃO DA UFSC?

O Estudo de Caso aborda a atuação profissional de egressos, modalidade presencial, do Curso de Administração (2011-2014), da Universidade Federal de Santa Catarina (CAD-UFSC). Da população de 548 bacharéis da lista de Graduados deste Survey, obteve-se a Amostra de 146 investigados, num Intervalo de Confiança de 95% e Erro Amostral de 7% (RENDER, STAIR JR.; HANNA, 2010). O questionário foi estruturado com perguntas fechadas Estilo Likert (HAIR JR., ANDERSON; TATHAM; BLACK, 2005), fixado no Google Docs e enviado por e-mail a todos egressos do período. A coleta foi feita em maio e junho de 2015, o tratamento dos dados foi quantitativo e usou-se o SPSS® na sua operacionalização. A pesquisa apontou que predominam os egressos na faixa etária de 26 a 30 anos (50,7%), sendo 50,7% do sexo feminino, a maioria natural do Estado de Santa Catarina, cursaram o ensino médio em escola privada e que cerca de 30% fez intercâmbio no exterior durante a graduação. Eles trabalham em empresas de médio porte e a faixa salarial predominante oscila de 3 a 6 salários mínimos, mas a maioria deles fez ou está cursando pós-graduação. Realçam à relevância em terem se graduado na UFSC, pois lhes permitiu reconhecimento pessoal e profissional, reforçando as avaliações do CAD-UFSC como um dos cursos 5 estrelas pelo MEC-Brasil

Characterization of mycobacteria and mycobacteriophages isolated from compost at the São Paulo Zoo Park Foundation in Brazil and creation of the new mycobacteriophage Cluster U

Background: A large collection of sequenced mycobacteriophages capable of infecting a single host strain of Mycobacterium smegmatis shows considerable genomic diversity with dozens of distinctive types (clusters) and extensive variation within those sharing evident nucleotide sequence similarity. Here we profiled the mycobacterial components of a large composting system at the São Paulo zoo. Results: We isolated and sequenced eight mycobacteriophages using Mycobacterium smegmatis mc2155 as a host. None of these eight phages infected any of mycobacterial strains isolated from the same materials. The phage isolates span considerable genomic diversity, including two phages (Barriga, Nhonho) related to Subcluster A1 phages, two Cluster B phages (Pops, Subcluster B1; Godines, Subcluster B2), three Subcluster F1 phages (Florinda, Girafales, and Quico), and Madruga, a relative of phage Patience with which it constitutes the new Cluster U. Interestingly, the two Subcluster A1 phages and the three Subcluster F1 phages have genomic relationships indicating relatively recent evolution within a geographically isolated niche in the composting system. Conclusions: We predict that composting systems such as those used to obtain these mycobacteriophages will be a rich source for the isolation of additional phages that will expand our view of bacteriophage diversity and evolution

Severe form of lymphocutaneous sporotrichosis: a case report

Sporotrichosis is the most frequent subcutaneous mycosis in Latin America. It is caused by species of the genus Sporothrix. Infection in humans occurs through the entry of the fungus into the skin. Zoonotic outbreaks involving cats in the transmission of the disease have been frequently reported. The lymphocutaneous form is the most commonly observed and the upper limbs are the most affected sites. We report a case of a 64-year-old healthy female patient with a lymphocutaneous form with rapid progression of lesions, which was refractory to initial treatment with itraconazole. Treatment with liposomal amphotericin B was performed with a satisfactory resolution, but aesthetic and functional sequelae in the left upper limb were installed

Resveratrol and grape juice differentially ameliorate cardiovascular autonomic modulation in L-NAME-treated rats

Polyphenols consumption detected in red wine and grape juice may prevent or help in the treatment of hypertension. However, cardiovascular autonomic effects of polyphenols were poorly studied. Therefore, we evaluated the effects of resveratrol and grape juice treatments in hemodynamics, baroreflex sensitivity, heart rate (HR) and blood pressure (BP) variability and cardiac redox parameters. Male Wistar rats were divided in 3 groups (n = 7/each) and treated for 30 days: only L-NAME-treated (60 mg/kg/day by oral gavage), L-NAME + resveratrol (L-NAME + R) and L-NAME + grape juice (L-NAME + G). BP signal was directly recorded and pulse interval (PI) and systolic arterial pressure (SAP) variability were analyzed in time and frequency domains. Baroreflex sensitivity (BRS) was determined by the alpha index. Oxidized and reduced glutathione concentrations were determined in cardiac tissue. L-NAME increased BP with no differences among groups (mean BP: L-NAME = 124 +/- 4, L-NAME + R = 126 +/- 3 and L-NAME + G = 125 +/- 4 mmHg). PI and SAP variability expressed by total variance were also similar among groups. However, normalized low frequency (LF) and high frequency (HF) components of PI variability were lower and higher, respectively, in both R and G-treated groups when compared to only L-NAME group. Interestingly, sympathetic modulation to the vessels (LF from SAP variability) and BRS were decreased and increased, respectively, only in L-NAME + R rats. Additionally, GSH/GSSG ratios were higher in L-NAME + R and L-NAME + G than in L-NAME group. Our results indicate that resveratrol and grape juice treatments can modulate autonomic function and promote cardiac redox benefits even when nitric oxide is decreased. Moreover, resveratrol influences not only cardiac but also vascular autonomic modulation. (C) 2013 Elsevier B.V. All rights reserved.Univ São Paulo, Escola Paulista Med, Inst Coracao InCor, Unidade Hipertensao, São Paulo, BrazilUniv Fed Ciencias Saude, Dept Ciencias Basicas Saude, Porto Alegre, RS, BrazilFundacao Univ Cardiol, Inst Cardiol, Unidade Pesquisa, Porto Alegre, RS, BrazilUniv Maranhao, UFMA, Hosp Univ Matemo Infantil, Sao Luis, BrazilUniv São Paulo, Escola Paulista Med, Inst Coracao InCor, Unidade Hipertensao, São Paulo, BrazilWeb of Scienc

IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis

Chagas disease is caused by the intracellular parasite Trypanosoma cruzi. This infection has been considered one of the most neglected diseases and affects several million people in the Central and South America. Around 30% of the infected patients develop digestive and cardiac forms of the disease. Most patients are diagnosed during the chronic phase, when the treatment is not effective. Here, we showed by the first time that IL-17 is produced during experimental T. cruzi infection and that it plays a significant role in host defense, modulating parasite-induced myocarditis. Applying this analysis to humans could be of great value in unraveling the elements involved in the pathogenesis of chagasic cardiopathy and could be used in the development of alternative therapies to reduce morbidity during the chronic phase of the disease, as well as clinical markers of disease progression. The understanding of these aspects of disease may be helpful in reducing the disability-adjusted life years (DALYs) and costs to the public health service in developing countries