Transthyretin familial amyloid polyneuropathy impact on health-related quality of life

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A new species of Daldinia (Xylariaceae) from the Argentine subtropical montane forest

Based on a combination of morphological, molecular phylogenetic and chemotaxonomic evidence, a new species of Daldinia from Northwest of Argentina is described. Daldinia korfii is morphologically related to D. placentiformis, but differs in having brown vinaceous, KOH-extractable pigments and the tissue below the perithecial layer is composed of inconspicuous to conspicuous alternating zones in the new taxon.Fil: Sir, Esteban Benjamin. Fundación Miguel Lillo. Dirección de Botánica. Instituto de Micologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Lambert, C.. Helmholtz-Zentrum für Infektionsforschung; AlemaniaFil: Wendt, L.. Helmholtz-Zentrum für Infektionsforschung; AlemaniaFil: Hladki, Adriana Ines. Fundación Miguel Lillo. Dirección de Botánica. Instituto de Micologia; ArgentinaFil: Romero, Andrea Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; ArgentinaFil: Stadler, M.. Helmholtz-Zentrum für Infektionsforschung; Alemani

A Validated Reversed-Phase HPLC Method for the Determination of Atorvastatin Calcium in Tablets

A Reversed-Phase Liquid Chromatographic (RP-LC) assay method was developed for the quantitative determination of atorvastatin calcium in the presence of its degradation products. The assay involved an isocratic elution of atorvastatin calcium in a LiChroCARTR 250*4 mm HPLC Cartridge LiChrospherR 100 RP-18 (5 μm) column using a mobile phase consisting of 0.1% acetic acid solution: acetonitrile (45:55, v/v), pH = 3.8. The flow rate was 0.8 mL/min and the analytes monitored at 246 nm. The assay method was found to be linear from 8.13 to 23.77 μg/mL. All the validation parameters were within the acceptance range. The developed method was successfully applied to estimate the amount of atorvastatin calcium in tablets.Fil: Simionato, Laura Daniela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaFil: Ferello, L.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaFil: Stamer. S.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaFil: Repetto, M. F.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaFil: Zubata, P. D.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; ArgentinaFil: Segall, Adriana Ines. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentin

Soil erosion modeling or a microwatershed

The objective of this study was to develop a soil erosion model for a microwatershed.  The selected watershed area was 2.64 hectares under forest area with plantation crops. Soil erosion factors identified were precipitation, stone cover, soil physical properties, height of vegetation, slope steepness and ground cover.  From this mechanism, values of permanent interception, soil cohesion, erosive rainfall intensity, evapotranspiration and infiltration was established. Composition of precipitation, evapotranspiration, infiltration and surface runoff was the water balance basis for the model structure developed.   Soil erosion equation (RMMF) model by Morgan was modified.  Secondary equation, the kinetic energy of leaf drainage (KE(LD)) was replaced with the kinetic energy equation.   Event surface runoff from the original equation of the model was enhanced; it was applied based on the water balance equation (Rs = P – ET – F).  Stone cover factor was added to the equation of energy because it has an effect to the raindrop impact. The new model was calibrated and validated by comparing the observed and adjusted soil erosion values for the selected rainfall-runoff event of May to September, 2012.  Analysis of data sets used in the calibration of the model yielded calibration equation of Adjusted Dt = 0.456*Dt – 0.878.  Data sets during the calibration had correlation coefficient of 90.30%, root mean square error (RMSE) of 27.5 % and coefficient of determination was 81.5%. Calibration equation was included in the model to come up with the final equation that determined total soil erosion rate. In the validation of final model, adjusted detachment rate and the observed value posted 97.9% correlation with root mean square error of 56%. The model could be used as prediction measure in the design and construction of channel structures as well as soil and water conservation practices that may reduce soil erosion

Simple “Market Value” Bargaining Model for Weighted Voting Games: Characterization and Limit Theorems

Feld, Grofman and Ray (2003) offer a bargaining model for weighted voting games that is a close relative of the nucleolus and the kernel. They look for a set of weights that preserves winning coalitions that has the property of minimizing the difference between the weight of the smallest and the weight of the largest Minimum Winning Coalition. They claim that such a set of weights provides an a priori measure of a weighted voter’s bribeworthiness or market value. Here, after reviewing the basic elements of their model, we provide a characterization result for this model and show its links to other bargaining model approaches in the literature. Then we offer some limit results showing that, with certain reasonable conditions on the distributions of weights, as the size of the voting body increases, the values of bribeworthiness we calculate will approach both the weights themselves and the Banzhaf scores for the weighted voting game. We also show that, even for relatively small groups using weighted voting, such as the membership of the European Council of Ministers (and its precedessors) 1958-2003, similarities among the usual a priori power scores, bribeworthiness/market value, and the weights themselves, will be quite strong

PyTranSpot\texttt{PyTranSpot} - A tool for multiband light curve modeling of planetary transits and stellar spots

Several studies have shown that stellar activity features, such as occulted and non-occulted starspots, can affect the measurement of transit parameters biasing studies of transit timing variations and transmission spectra. We present $\texttt{PyTranSpot}$, which we designed to model multiband transit light curves showing starspot anomalies, inferring both transit and spot parameters. The code follows a pixellation approach to model the star with its corresponding limb darkening, spots, and transiting planet on a two dimensional Cartesian coordinate grid. We combine $\texttt{PyTranSpot}$ with an MCMC framework to study and derive exoplanet transmission spectra, which provides statistically robust values for the physical properties and uncertainties of a transiting star-planet system. We validate $\texttt{PyTranSpot}$'s performance by analyzing eleven synthetic light curves of four different star-planet systems and 20 transit light curves of the well-studied WASP-41b system. We also investigate the impact of starspots on transit parameters and derive wavelength dependent transit depth values for WASP-41b covering a range of 6200-9200 $\AA$, indicating a flat transmission spectrum.Comment: 17 pages, 22 figures; accepted for publication in Astronomy & Astrophysic

Soil Erosion Modeling or a Microwatershed

The objective of this study was to develop a soil erosion model for a microwatershed. The selected watershed area was 2.64 hectares under forest area with plantation crops. Soil erosion factors identified were precipitation, stone cover, soil physical properties, height of vegetation, slope steepness and ground cover. From this mechanism, values of permanent interception, soil cohesion, erosive rainfall intensity, evapotranspiration and infiltration was established. Composition of precipitation, evapotranspiration, infiltration and surface runoff was the water balance basis for the model structure developed. Soil erosion equation (RMMF) model by Morgan was modified. Secondary equation, the kinetic energy of leaf drainage (KE(LD)) was replaced with the kinetic energy equation. Event surface runoff from the original equation of the model was enhanced; it was applied based on the water balance equation (Rs = P – ET – F). Stone cover factor was added to the equation of energy because it has an effect to the raindrop impact. The new model was calibrated and validated by comparing the observed and adjusted soil erosion values for the selected rainfall-runoff event of May to September, 2012. Analysis of data sets used in the calibration of the model yielded calibration equation of Adjusted Dt = 0.456*Dt – 0.878. Data sets during the calibration had correlation coefficient of 90.30%, root mean square error (RMSE) of 27.5 % and coefficient of determination was 81.5%. Calibration equation was included in the model to come up with the final equation that determined total soil erosion rate. In the validation of final model, adjusted detachment rate and the observed value posted 97.9% correlation with root mean square error of 56%. The model could be used as prediction measure in the design and construction of channel structures as well as soil and water conservation practices that may reduce soil erosion