Patient adherence to medical treatment: a review of reviews

BACKGROUND: Patients' non-adherence to medical treatment remains a persistent problem. Many interventions to improve patient adherence are unsuccessful and sound theoretical foundations are lacking. Innovations in theory and practice are badly needed. A new and promising way could be to review the existing reviews of adherence to interventions and identify the underlying theories for effective interventions. That is the aim of our study. METHODS: The study is a review of 38 systematic reviews of the effectiveness of adherence interventions published between 1990 and 2005. Electronic literature searches were conducted in Medline, Psychinfo, Embase and the Cochrane Library. Explicit inclusion and exclusion criteria were applied. The scope of the study is patient adherence to medical treatment in the cure and care sector. RESULTS: Significant differences in the effectiveness of adherence interventions were found in 23 of the 38 systematic reviews. Effective interventions were found in each of four theoretical approaches to adherence interventions: technical, behavioural, educational and multi-faceted or complex interventions. Technical solutions, such as a simplification of the regimen, were often found to be effective, although that does not count for every therapeutic regimen.Overall, our results show that, firstly, there are effective adherence interventions without an explicit theoretical explanation of the operating mechanisms, for example technical solutions. Secondly, there are effective adherence interventions, which clearly stem from the behavioural theories, for example incentives and reminders. Thirdly, there are other theoretical models that seem plausible for explaining non-adherence, but not very effective in improving adherence behaviour. Fourthly, effective components within promising theories could not be identified because of the complexity of many adherence interventions and the lack of studies that explicitly compare theoretical components. CONCLUSION: There is a scarcity of comparative studies explicitly contrasting theoretical models or their components. The relative weight of these theories and the effective components in the interventions designed to improve adherence, need to be assessed in future studies. (aut.ref.

Bygging av Lysebotn II (Lyse Produksjon) og Lyse transformatorstasjon (Statnett). Sluttrapport miljøoppølging vannkvalitet 2016 og 2017

To større prosjekter hadde omfattende anleggsvirksomhet i Lysebotn gjennom 2016 og 2017. Nytt vannkraftverk, Lysebotn II, ble bygd av Lyse Produksjon ved entreprenør Implenia. Ny transformatorstasjon ble bygd av Statnett med grunnarbeider gjennomført av entreprenør Risa AS. Prosjektene kunne gi fare for avrenning og påvirkning av vannkvalitet i de lakse- og sjøørretførende elvene Stølsåna og Lyseåna. Vassdragene er viktige estetiske elementer for turismen i Lysebotn. Som en del av MOP- og MTA-plan for prosjektene har det blitt gjennomført automatisk overvåking av vannkvaliteten i disse vassdragene mens anleggsarbeidet har pågått. NIBIO har gjennomført denne overvåkingen etter oppdrag fra Lyse Produksjon og Statnett

Nature, level and type of networking for individuals with dual diagnosis:a European perspective

Aim: To obtain more detailed information on service availability and appropriateness and interagency networking for individuals with dual diagnosis (DD) at seven European centres.Methods: Data was collected using two parts of the three-part Treatment of Dual Diagnosis tool in seven European centres as part of the Integrated Services Aimed at Dual Diagnosis and Optimal Recovery from Addiction (ISADORA) study between 2002 and 2005 focusing on the nature, level and type of networking for individuals with co-morbid mental health and substance misuse problems (DD). A multi-level process of qualifying networking was used.Findings: Findings show that 50-90% of the listed centres across the ISADORA sites reported some level of networking but only 30% had a joint care agreement in place or shared patient/client records with at least one other agency. Barriers and facilitators to interagency collaboration are described.Conclusion: This pan-European study highlighted the need for a more integrated and focused approach to DD service delivery.</p

Predictors of service use of patients with co-morbid mental health and substance use disorders across seven European sites

The purpose of this study was to identify factors which predict service use over time in patients with co-morbid mental health and substance use disorders (dual diagnosis). Three hundred and fifty-two patients with dual diagnosis were recruited from acute psychiatric inpatient units at seven European sites. At baseline and 9 months follow-up, socio-demographic and clinical information, as well as information concerning the use of treatment services was collected. Predictors for use of psychiatric and substance misuse services at follow-up were studied using multinomial logistic regression models. At follow-up, patients with dual diagnosis used psychiatric services significantly more than substance use services. The main predictor of service use at follow-up is influenced by the study site and not by psychopathology. More networking and signposting are needed especially for substance misuse services. Service provision and planning can improve access of vulnerable populations even when psychopathology improves

The 2009 Schizophrenia PORT Psychosocial Treatment Recommendations and Summary Statements

The Schizophrenia Patient Outcomes Research Team (PORT) psychosocial treatment recommendations provide a comprehensive summary of current evidence-based psychosocial treatment interventions for persons with schizophrenia. There have been 2 previous sets of psychosocial treatment recommendations (Lehman AF, Steinwachs DM. Translating research into practice: the Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations. Schizophr Bull. 1998;24:1–10 and Lehman AF, Kreyenbuhl J, Buchanan RW, et al. The Schizophrenia Patient Outcomes Research Team (PORT): updated treatment recommendations 2003. Schizophr Bull. 2004;30:193–217). This article reports the third set of PORT recommendations that includes updated reviews in 7 areas as well as adding 5 new areas of review. Members of the psychosocial Evidence Review Group conducted reviews of the literature in each intervention area and drafted the recommendation or summary statement with supporting discussion. A Psychosocial Advisory Committee was consulted in all aspects of the review, and an expert panel commented on draft recommendations and summary statements. Our review process produced 8 treatment recommendations in the following areas: assertive community treatment, supported employment, cognitive behavioral therapy, family-based services, token economy, skills training, psychosocial interventions for alcohol and substance use disorders, and psychosocial interventions for weight management. Reviews of treatments focused on medication adherence, cognitive remediation, psychosocial treatments for recent onset schizophrenia, and peer support and peer-delivered services indicated that none of these treatment areas yet have enough evidence to merit a treatment recommendation, though each is an emerging area of interest. This update of PORT psychosocial treatment recommendations underscores both the expansion of knowledge regarding psychosocial treatments for persons with schizophrenia at the same time as the limitations in their implementation in clinical practice settings