1,022 research outputs found
Fruit Color Properties of Different Cultivars of Dates (Phoenix dactylifera, L.)
Rosana G. Moreira, Editor-in-Chief; Texas A&M UniversityThis is a paper from International Commission of Agricultural Engineering (CIGR, Commission Internationale du Genie Rural) E-Journal Volume 8 (2006): Fruit Color Properties of Different Cultivars of Dates (Phoenix dactylifera, L.). Manuscript FP 05 005. Vol. VIII. March, 2006
Yeast Features: Identifying Significant Features Shared Among Yeast Proteins for Functional Genomics
Background
High throughput yeast functional genomics experiments are revealing associations among tens to hundreds of genes using numerous experimental conditions. To fully understand how the identified genes might be involved in the observed system, it is essential to consider the widest range of biological annotation possible. Biologists often start their search by collating the annotation provided for each protein within databases such as the Saccharomyces Genome Database, manually comparing them for similar features, and empirically assessing their significance. Such tasks can be automated, and more precise calculations of the significance can be determined using established probability measures. 
Results
We developed Yeast Features, an intuitive online tool to help establish the significance of finding a diverse set of shared features among a collection of yeast proteins. A total of 18,786 features from the Saccharomyces Genome Database are considered, including annotation based on the Gene Ontology’s molecular function, biological process and cellular compartment, as well as conserved domains, protein-protein and genetic interactions, complexes, metabolic pathways, phenotypes and publications. The significance of shared features is estimated using a hypergeometric probability, but novel options exist to improve the significance by adding background knowledge of the experimental system. For instance, increased statistical significance is achieved in gene deletion experiments because interactions with essential genes will never be observed. We further demonstrate the utility by suggesting the functional roles of the indirect targets of an aminoglycoside with a known mechanism of action, and also the targets of an herbal extract with a previously unknown mode of action. The identification of shared functional features may also be used to propose novel roles for proteins of unknown function, including a role in protein synthesis for YKL075C.
Conclusions
Yeast Features (YF) is an easy to use web-based application (http://software.dumontierlab.com/yeastfeatures/) which can identify and prioritize features that are shared among a set of yeast proteins. This approach is shown to be valuable in the analysis of complex data sets, in which the extracted associations revealed significant functional relationships among the gene products.

Analysis of ischaemic crisis using the informational causal entropy-complexity plane
In the present work, an ischaemic process, mainly focused on the reperfusion stage, is studied using the informational causal entropy-complexity plane. Ischaemic wall behavior under this condition was analyzed through wall thickness and ventricular pressure variations, acquired during an obstructive flow maneuver performed on left coronary arteries of surgically instrumented animals. Basically, the induction of ischaemia depends on the temporary occlusion of left circumflex coronary artery (which supplies blood to the posterior left ventricular wall) that lasts for a few seconds. Normal perfusion of the wall was then reestablished while the anterior ventricular wall remained adequately perfused during the entire maneuver. The obtained results showed that system dynamics could be effectively described by entropy-complexity loops, in both abnormally and well perfused walls. These results could contribute to making an objective indicator of the recovery heart tissues after an ischaemic process, in a way to quantify the restoration of myocardial behavior after the supply of oxygen to the ventricular wall was suppressed for a brief period.Fil: Legnani, Walter. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina. Universidad Nacional de Lanús; ArgentinaFil: Traversaro Varela, Francisco. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Redelico, Francisco Oscar. Hospital Italiano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; ArgentinaFil: Cymberknop, Leandro Javier. Instituto Tecnologico de Buenos Aires. Departamento de Bioingenieria; Argentina. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; ArgentinaFil: Armentano, Ricardo Luis. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina. Instituto Tecnologico de Buenos Aires. Departamento de Bioingenieria; ArgentinaFil: Rosso, Osvaldo Aníbal. Universidad de los Andes; Chile. Universidade Federal de Alagoas; Brasil. Hospital Italiano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
Magnetically geared induction machines
A wound-rotor induction machine is artfully coupled to a magnetic gear to achieve a high-torque-density drive system called magnetically geared induction machine (MaGIM). The high-speed rotor of MaGIM is common to both the machine and gear sides. A rotating diode rectifier electrically links the machine's wound rotor and a dc boost winding on the gear side to increase the torque-transmission capabilities of the overall system. The first investigations on a 100 kW-120 r/min MaGIM are promising, since an increase in torque of ∼ 15% could be obtained by inserting the diode rectifier. For fixed speed applications, this induction-machine-based system can be directly supplied from the main
Heme oxygenase effect on mesenchymal stem cells action on experimental Alzheimer's disease
The objective is to evaluate the effect of heme oxygenase-1 (HO-1) enzyme inducer and inhibitor on Mesenchymal Stem Cells (MSCs) in Alzheimer disease. Materials and Methods: 70 female albino rats were divided equally into 7 groups as follows:
group 1: healthy control; group 2: Aluminium chloride induced Alzheimer disease; group 3:
induced Alzheimer rats that received intravenous injection of MSCs; group 4: induced Alzheimer rats that received MSCs and HO inducer cobalt protoporphyrin; group 5: induced Alzheimer rats that received MSCs and HO inhibitor zinc protoporphyrin; group 6: induced Alzheimer rats that received HO inducer; group7: induced Alzheimer rats that received HO inhibitor. Brain tissue was collected for HO-1, seladin-1 gene expression by real time polymerase chain reaction, heme oxygenase activity, cholesterol estimation and histopathological examination. Results: MSCs decreased the plaque lesions, heme oxygenase induction with stem cells also decreased plaque lesions however there was hemorrhage in the brain. Both heme oxygenase inducer alone or with stem cells increased seladin-1 expression and decreased cholesterol level.
Conclusion: MSCs alone or with HO-1 induction
exert a therapeutic effect against the brain
lesion in Alzheimer’s disease possibly through decreasing the brain cholesterol level and increasing seladin-1 gene expression
Experimental Indicators of Accretion Processes in Active Galactic Nuclei
Bright Active Galactic Nuclei are powered by accretion of mass onto the super
massive black holes at the centers of the host galaxies. For fainter objects
star formation may significantly contribute to the luminosity. We summarize
experimental indicators of the accretion processes in Active Galactic Nuclei
(AGN), i.e., observable activity indicators that allow us to conclude on the
nature of accretion. The Galactic Center is the closest galactic nucleus that
can be studied with unprecedented angular resolution and sensitivity.
Therefore, here we also include the presentation of recent observational
results on Sagittarius A* and the conditions for star formation in the central
stellar cluster. We cover results across the electromagnetic spectrum and find
that the Sagittarius A* (SgrA*) system is well ordered with respect to its
geometrical orientation and its emission processes of which we assume to
reflect the accretion process onto the super massive black hole.Comment: 16 pages, 4 figures, conference proceeding: Accretion Processes in
Cosmic Sources - APCS2016 - 5-10 September 2016, Saint Petersburg, Russi
Modelling and control of a multi-stage interleaved DC-DC converter with coupled inductors for super-capacitor energy storage system
Interleaved converters with coupled inductors are widely used to share load current in high power applications. It offers high equivalent switching frequency and reduced output current ripples using small size magnetic components. Due to smaller common-mode inductance, control system can be designed to achieve fast dynamic response. This paper proposes 8 channel interleaved DC/DC converter for interfacing super-capacitor energy storage system to a 400V DC voltage bus. Multi-stage interleaving magnetic circuit with two-phase coupling inductor as a building block is proposed. A methodology is developed to construct the model of the multi-stage magnetic circuit from the basic two-phase coupled inductor model. The derived model is successfully used to evaluate the system power losses and to design the magnetic circuit parameters and its current controller to fulfil the DC/DC converter steady state and dynamic performance specifications. A 20kW/four stage/8 channel DC/DC converter laboratory prototype has been built to connect a super-capacitor stack to 400V DC voltage bus. Experimental investigation validates the modeling, the system losses calculations and the design specifications of the system
The impact of Stieltjes' work on continued fractions and orthogonal polynomials
Stieltjes' work on continued fractions and the orthogonal polynomials related
to continued fraction expansions is summarized and an attempt is made to
describe the influence of Stieltjes' ideas and work in research done after his
death, with an emphasis on the theory of orthogonal polynomials
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