The Cluster of Galaxies Abell 970

We present a dynamical analysis of the galaxy cluster Abell 970 based on a new set of radial velocities measured at ESO, Pic du Midi and Haute-Provence observatories. Our analysis indicates that this cluster has a substructure and is out of dynamical equilibrium. This conclusion is also supported by differences in the positions of the peaks of the surface density distribution and X-ray emission, as well as by the evidence of a large scale velocity gradient in the cluster. We also found a discrepancy between the masses inferred with the virial theorem and with the X-ray emission, what is expected if the galaxies and the gas inside the cluster are not in hydrostatic equilibrium. Abell 970 has a modest cooling flow, as is expected if it is out of equilibrium as suggested by Allen (1998). We propose that cooling flows may have an intermittent behavior, with phases of massive cooling flows being followed by phases without significant cooling flows after the acretion of a galaxy group massive enough to disrupt the dynamical equilibrium in the center of the clusters. A massive cooling flow will be established again, after a new equilibrium is achieved.Comment: 24 pages, 9 figures, submitted to A&

A Dark Core in Abell 520

The rich cluster Abell 520 (z=0.201) exhibits truly extreme and puzzling multi-wavelength characteristics. It may best be described as a "cosmic train wreck." It is a major merger showing abundant evidence for ram pressure stripping, with a clear offset in the gas distribution compared to the galaxies (as in the bullet cluster 1E 0657-558). However, the most striking feature is a massive dark core (721 h_70 M_sun/L_sun) in our weak lensing mass reconstruction. The core coincides with the central X-ray emission peak, but is largely devoid of galaxies. An unusually low mass to light ratio region lies 500 kpc to the east, and coincides with a shock feature visible in radio observations of the cluster. Although a displacement between the X-ray gas and the galaxy/dark matter distributions may be expected in a merger, a mass peak without galaxies cannot be easily explained within the current collisionless dark matter paradigm. Interestingly, the integrated gas mass fraction (~0.15), mass-to-light ratio (220 h_70 M_sun/L_sun), and position on the X-ray luminosity-temperature and mass-temperature relations are unremarkable. Thus gross properties and scaling relations are not always useful indicators of the dynamical state of clusters.Comment: 10 pages, 5 figures, accepted for publication in the Astrophysical Journal, higher resolution version at http://visav.phys.uvic.ca/~amahdav

The cluster of galaxies Abell 376

We present a dynamical analysis of the galaxy cluster Abell 376 based on a set of 73 velocities, most of them measured at Pic du Midi and Haute-Provence observatories and completed with data from the literature. Data on individual galaxies are presented and the accuracy of the determined velocities is discussed as well as some properties of the cluster. We obtained an improved mean redshift value z=0.0478^{+0.005}_{-0.006} and velocity dispersion sigma=852^{+120}_{-76}km/s. Our analysis indicates that inside a radius of 900h_{70}^{-1}kpc (15 arcmin) the cluster is well relaxed without any remarkable feature and the X-ray emission traces fairly well the galaxy distribution. A possible substructure is seen at 20 arcmin from the centre towards the Southwest direction, but is not confirmed by the velocity field. This SW clump is, however, kinematically bound to the main structure of Abell 376. A dense condensation of galaxies is detected at 46 arcmin (projected distance 2.6h_{70}^{-1}Mpc) from the centre towards the Northwest and analysis of the apparent luminosity distribution of its galaxies suggests that this clump is part of the large scale structure of Abell 376. X-ray spectroscopic analysis of ASCA data resulted in a temperature kT = 4.3+/-0.4 keV and metal abundance Z = 0.32+/-0.08 Z_solar. The velocity dispersion corresponding to this temperature using the T_X-sigma scaling relation is in agreement with the measured galaxies velocities.Comment: 11 pages, 10 figures, accepted for publication in A&

Quantum-Classical Crossover and Apparent Metal-Insulator Transition in a Weakly Interacting 2D Fermi Liquid

We report the observation of a parallel magnetic field induced metal-insulator transition (MIT) in a high-mobility two-dimensional electron gas (2DEG) for which spin and localization physics most likely play no major role. The high-mobility metallic phase at low field is consistent with the established Fermi liquid transport theory including phonon scattering, whereas the insulating phase at higher field shows a large negative temperature dependence at resistances much smaller than the quantum of resistance, $h/e^2$. We argue that this observation is a direct manifestation of a quantum-classical crossover arising predominantly from the magneto-orbital coupling between the finite width of the 2DEG and the in-plane magnetic field.Comment: 4 pages, 2 figure

Competing types of quantum oscillations in the 2D organic conductor (BEDT-TTF)8Hg4Cl12(C6H5Cl)2

Interlayer magnetoconductance of the quasi-two dimensional organic metal (BEDT-TTF)8Hg4Cl12(C6H5Cl)2 has been investigated in pulsed magnetic fields extending up to 36 T and in the temperature range from 1.6 to 15 K. A complex oscillatory spectrum, built on linear combinations of three basic frequencies only is observed. These basic frequencies arise from the compensated closed hole and electron orbits and from the two orbits located in between. The field and temperature dependencies of the amplitude of the various oscillation series are studied within the framework of the coupled orbits model of Falicov and Stachowiak. This analysis reveals that these series result from the contribution of either conventional Shubnikov-de Haas effect (SdH) or quantum interference (QI), both of them being induced by magnetic breakthrough. Nevertheless, discrepancies between experimental and calculated parameters indicate that these phenomena alone cannot account for all of the data. Due to its low effective mass, one of the QI oscillation series - which corresponds to the whole first Brillouin zone area - is clearly observed up to 13 K.Comment: 8 pages, 8 figures. To be published in Phys. Rev.

Fermi-surface reconstruction and two-carrier model for the Hall effect in YBa2Cu4O8

Pulsed field measurements of the Hall resistivity and magnetoresistance of underdoped YBa2Cu4O8 are analyzed self-consistently using a simple model based on coexisting electron and hole carriers. The resultant mobilities and Hall numbers are found to vary markedly with temperature. The conductivity of the hole carriers drops by one order of magnitude below 30 K, explaining the absence of quantum oscillations from these particular pockets. Meanwhile the Hall coefficient of the electron carriers becomes strongly negative below 50 K. The overall quality of the fits not only provides strong evidence for Fermi-surface reconstruction in Y-based cuprates, it also strongly constrains the type of reconstruction that might be occurring.Comment: 5 pages, 4 figures, updated after publication in Physical Review B (Rapid Communication

Differential effects of SARS-CoV-2 variants on central nervous system cells and blood-brain barrier functions

BACKGROUND: Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus affects the brain and how the mutations carried by the different variants modulate those neurological symptoms remain unclear. METHODS: We used primary human pericytes, foetal astrocytes, endothelial cells and a microglial cell line to investigate the effect of several SARS-CoV-2 variants of concern or interest on their functional activities. Cells and a 3D blood-brain barrier model were infected with the wild-type form of SARS-CoV-2, Alpha, Beta, Delta, Eta, or Omicron (BA.1) variants at various MOI. Cells and supernatant were used to evaluate cell susceptibility to the virus using a microscopic assay as well as effects of infection on (i) cell metabolic activity using a colorimetric MTS assay; (ii) viral cytopathogenicity using the xCELLigence system; (iii) extracellular glutamate concentration by fluorometric assay; and (iv) modulation of blood-brain barrier permeability. RESULTS: We demonstrate that productive infection of brain cells is SARS-CoV-2 variant dependent and that all the variants induce stress to CNS cells. The wild-type virus was cytopathic to all cell types except astrocytes, whilst Alpha and Beta variants were only cytopathic for pericytes, and the Omicron variant cytopathic for endothelial cells and pericytes. Lastly wild-type virus increases blood-brain barrier permeability and all variants, except Beta, modulate extracellular glutamate concentration, which can lead to excitotoxicity or altered neurotransmission. CONCLUSIONS: These results suggest that SARS-CoV-2 is neurotropic, with deleterious consequences for the blood-brain barrier integrity and central nervous system cells, which could underlie neurological disorders following SARS-CoV-2 infection