Wavelet analysis of beam-soil structure response for fast moving train

This paper presents a wavelet based approach for the vibratory analysis of beam-soil structure related to a point load moving along a beam resting on the surface. The model is represented by the Euler-Bernoulli equation for the beam, elastodynamic equation of motion for the soil and appropriate boundary conditions. Two cases are analysed: the model with a half space under the beam and the model where the supporting medium has a finite thickness. Analytical solutions for the displacements are obtained and discussed in relation to the used boundary conditions and the type of considered loads: harmonic and constant. The analysis in time-frequency and velocity-frequency domains is carried out for realistic systems of parameters describing physical properties of the model. The approximate displacement values are determined by applying a wavelet method for a derivation of the inverse Fourier transform. A special form of the coiflet filter used in numerical calculations allows to carry out analysis without loss of accuracy related to singularities appearing in wavelet approximation formulas, when dealing with standard filters and complex dynamic systems. © 2009 IOP Publishing Ltd

Fixed-base simulation evaluation of various low-visibility landing systems for helicopters

Fixed base simulation evaluation of one fully automatic and six manual low visibility landing systems for helicopter

Aircraft control system

An aircraft control system is described which is particularly suited to rotary wing aircraft. Longitudinal acceleration and course rate commands are derived from a manual control stick to control translational velocity of the aircraft along a flight path. In the collective channel the manual controls provide vertical velocity commands. In the yaw channel the manual controls provide sideslip or heading rate commands at high or low airspeeds, respectively. The control system permits pilots to fly along prescribed flight paths in a precise manner with relatively low work load

What Does an Exemplary Middle School Mathematics Teacher Look Like? The Use of a Professional Development Rubric

A School University Research Network (SURN) committee composed of current mathematics teachers, central office math supervisors, building administrators, mathematicians, and mathematics educators researched numerous sources regarding best practices in mathematics instruction. The resulting professional development rubric synthesizes their findings and can serve a professional development role by providing teachers and administrators with a tool to develop clarity and consensus on best mathematics instructional practices, and how these practices are implemented in the classroom. It is also being used as a tool for cooperating teachers in their supervision of student teachers and as a reflective method for self-evaluation

Insights into in vivo adipocyte differentiation through cell-specific labeling in zebrafish.

White adipose tissue hyperplasia has been shown to be crucial for handling excess energy in healthy ways. Though adipogenesis mechanisms have been underscored in vitro, we lack information on how tissue and systemic factors influence the differentiation of new adipocytes. While this could be studied in zebrafish, adipocyte identification currently relies on neutral lipid labeling, thus precluding access to cells in early stages of differentiation. Here we report the generation and analysis of a zebrafish line with the transgene fabp4a(- 2.7):EGFPcaax. In vivo confocal microscopy of the pancreatic and abdominal visceral depots of transgenic larvae, revealed the presence of labeled mature adipocytes as well as immature cells in earlier stages of differentiation. Through co-labeling for blood vessels, we observed a close interaction of differentiating adipocytes with endothelial cells through cell protrusions. Finally, we implemented hyperspectral imaging and spectral phasor analysis in Nile Red-labeled transgenic larvae and revealed the lipid metabolic transition towards neutral lipid accumulation of differentiating adipocytes. Altogether our work presents the characterization of a novel adipocyte-specific label in zebrafish and uncovers previously unknown aspects of in vivo adipogenesis.Agencia Nacional de Investigación e InnovaciónPrograma de Desarrollo de las Ciencias BásicasFondo de Convergencia Estructural del Mercosu

LHC Beam Instrumentation

Six years before the scheduled commissioning of the LHC at CERN, the basic list of beam instruments has been established. This early date is needed due to the impact of the mechanical design of some detectors (mainly the beam position detectors) on the cryogenic part of the machine as well as for other projects due to the long R&D period (emittance measurements, tune and chromaticity diagnostics and control). This paper gives a detailed overview of the basic requirements and specifications of all beam instruments foreseen for transfer lines and main rings [1]

Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration.

BackgroundOne potential mechanism for early superficial cartilage wear in normal joints is alteration of the lubricant content and quality of synovial fluid. The purpose of this study was to determine if the concentration and quality of the lubricant, hyaluronan, in synovial fluid: (1) was similar in left and right knees; (2) exhibited similar age-associated trends, whether collected postmortem or antemortem; and (3) varied with age and grade of joint degeneration.MethodsHuman synovial fluid of donors (23-91 years) without osteoarthritis was analyzed for the concentrations of protein, hyaluronan, and hyaluronan in the molecular weight ranges of 2.5-7 MDa, 1-2.5 MDa, 0.5-1 MDa, and 0.03-0.5 MDa. Similarity of data between left and right knees was assessed by reduced major axis regression, paired t-test, and Bland-Altman analysis. The effect of antemortem versus postmortem collection on biochemical properties was assessed for age-matched samples by unpaired t-test. The relationships between age, joint grade, and each biochemical component were assessed by regression analysis.ResultsJoint grade and the concentrations of protein, hyaluronan, and hyaluronan in the molecular weight ranges of 2.5-7 MDa, 1-2.5 MDa, and 0.5-1 MDa in human synovial fluid showed good agreement between left and right knees and were similar between age-matched patient and cadaver knee joints. There was an age-associated decrease in overall joint grade (-15 %/decade) and concentrations of hyaluronan (-10.5 %/decade), and hyaluronan in the molecular weight ranges of 2.5-7 MDa (-9.4 %/decade), 1-2.5 MDa (-11.3 %/decade), 0.5-1 MDa (-12.5 %/decade), and 0.03-0.5 MDa (-13.0 %/decade). Hyaluronan concentration and quality was more strongly associated with age than with joint grade.ConclusionsThe age-related increase in cartilage wear in non-osteoarthritic joints may be related to the altered hyaluronan content and quality of synovial fluid

LHC Beam Instrumentation Conceptual Design Report

The instruments and diagnostic systems considered for the LHC are presented and their specifications and expected performance discussed. Their task will be to measure the essential beam properties, establish diagnosis, and give information on beam behaviour. The diagnostic systems will be essential during the running-in period. Precise and reliable information from them are a prerequisite for operational optimization.During the last years, basic design and parameters of the LHC have evolved continuously. The present description of beam instrumentation and diagnostics is based on the most recent set of nominal LHC parameters