13,028 research outputs found

    Mechanical Systems: Symmetry and Reduction

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    Reduction theory is concerned with mechanical systems with symmetries. It constructs a lower dimensional reduced space in which associated conservation laws are taken out and symmetries are \factored out" and studies the relation between the dynamics of the given system with the dynamics on the reduced space. This subject is important in many areas, such as stability of relative equilibria, geometric phases and integrable systems

    Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis.

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    Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc). Ultra-conserved regions (UCRs) are a class non-coding sequences that are conserved in humans, mice and rats. More than 90% of UCRs are transcribed (T-UCRs) in normal tissues, and are altered at transcriptional level in tumorigenesis. To identify the T-UCR profiles that are dysregulated in Barretts mucosa transformation, microarray analysis was performed on a discovery set of 51 macro-dissected samples obtained from 14 long-segment BE patients. Results were validated in an independent series of esophageal biopsy/surgery specimens and in two murine models of Barretts esophagus (i.e. esophagogastric-duodenal anastomosis). Progression from normal to BE to adenocarcinoma was each associated with specific and mutually exclusive T-UCR signatures that included up-regulation of uc.58-, uc.202-, uc.207-, and uc.223- and down-regulation of uc.214+. A 9 T-UCR signature characterized BE versus Sq (with the down-regulation of uc.161-, uc.165-, and uc.327-, and the up-regulation of uc.153-, uc.158-, uc.206-, uc.274-, uc.472-, and uc.473-). Analogous BE-specific T-UCR profiles were shared by human and murine lesions. This study is the first demonstration of a role for T-UCRs in the transformation of Barretts mucosa

    The Perugia (Italy) earthquake of April 29,1984: a seismic survey

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    International audienceA field study after the Perugia earthquake of 29 April 1984 provided more than 300 well-recorded events concentrated within two parallel clusters separated by 2 km and trending along the Apenninic direction. The length of the aftershock area is 14 km, focal depths being shallower than 8 km. Relocation of the main event places the epicenter at the southern end of the aftershock zone, suggesting a rupture propagation from SE to NW. Most focal mechanisms are consistent with normal faulting. The spatial distribution of seismicity suggests that the Gubbio normal fault was activated during the main shock. This earthquake, together with the Norcia 1979 and the Abruzzi 1984 shocks, is typical of the extension in the high Apennines generated by the flexure of the mountain chain in response to regional compression. The Parma 1983 event, a thrust, belongs to the compres- sion zone at the eastern flank of the chain. These results are consistent with the EW continental collision along the Apennines

    First record of Darwin’s Slimehead, Gephyroberyx darwinii (Johnson, 1866) (Beryciformes: Trachichthyidae), in association with Brazilian deep reefs

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    Copyright © 2004 aqua, International Journal of Ichthyology.Três espécies da família Trachichthyidae ocorrem no sul do Brasil: Paratrachichthys atlanticus, Hoplostethus occidentalis e Gephyroberyx darwinii. Esta última é uma espécie que atinge tamanhos da ordem dos 600 mm (CT), vive na província bentopelágica até profundidades de 1210 metros. É encontrada em águas subtropicais distribuindo-se entre os paralelos 43ºN e 35ºS, sendo utilizada como fonte de alimento no leste do Atlântico central. O presente trabalho reporta a ocorrência de Gephyroberyx darwinii na costa brasileira entre as localidades de Vila Velha (ES) e Rio Grande (RS), em áreas de plataforma externa e talude superior, com profundidades variando de 70 a 520 metros. Suas ocorrências nestas áreas estiveram relacionadas a lances de pesca (onde Lophius gastrophysus é espécie alvo) sobre formações de corais vivos. Dados biométricos e merísticos de três espécimes são apresentados no trabalho.ABSTRACT: Three species of the Trachichthyidae family occur in the south of Brazil: Paratrachichthys atlanticus, Hoplostethus occidentalis and Gephyroberyx darwinii. G. darwinii may attain a length of 600 mm (TL). This benthopelagic species occurs at depths down to 1210 m and is generally found in subtropical waters between 43ºN and 35ºS. It is commercially exploited in the east central Atlantic for food and for oil. In this paper we report the occurrence of G. darwinii off the south and south-east coasts of Brazil between Vila Velha (Espírito Santo State) and Rio Grande (Rio Grande do Sul State), in outer shelf and slope areas, at depths between 70 and 520 m. In Brazil the trachichthyids were usually caught while fishing for Lophius gastrophysus over deep coral bottoms. Meristic and biometric data are presented for the three collected specimens

    Scaling of the superfluid density in superfluid films

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    We study scaling of the superfluid density with respect to the film thickness by simulating the xyx-y model on films of size L×L×HL \times L \times H (L>>HL >> H) using the cluster Monte Carlo. While periodic boundary conditions where used in the planar (LL) directions, Dirichlet boundary conditions where used along the film thickness. We find that our results can be scaled on a universal curve by introducing an effective thickness. In the limit of large HH our scaling relations reduce to the conventional scaling forms. Using the same idea we find scaling in the experimental results using the same value of ν=0.6705\nu = 0.6705.Comment: 4 pages, one postscript file replaced by one Latex file and 5 postscript figure
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