Female Correctional Workers:Perceptions of Sexual Abuse Training

Offenders return to the community after having been sexually abused by those who have been entrusted with the responsibility to protect them. The phenomenon of staff-on-inmate sexual abuse has become problematic within the criminal justice system. Research on the topic of sexual abuse in penal institutions reveals a lack of information pertaining to staff-on-inmate sexual abuse, and how correctional workers are trained in that area. Female correctional staff have been implicated in more incidences of staff-on-inmate sexual abuse than their male counterparts. The purpose of this phenomenological study was to explore sexual abuse training received by female correctional staff who were employed in a Mid Atlantic pre-release center, and to examine their perceptions of that training. The study was centered around the Thomas Theorem adopted by William Isaac Thomas. That theory postulates that an individuals\u27 actions are based on how they perceive a situation. Two research questions were addressed relating to sexual abuse training and perceptions of training. Semi-structured interviews were conducted which provided participants with an opportunity to express and describe new ideas relating to the topic. Data were analyzed using the Interpretive Phenomenological Analysis system because of its ability to address subjectivity. This research has revealed that sexual abuse training is developed for correctional staff as a collective and does not differentiate with respect to gender. In addition, it was concluded that correctional staff sexual abuse training lacks intensity and depth in terms of information disseminated. The results of this research will provide criminal justice scholars with information that could prove useful in future studies on the topic of staff -on-inmate sexual abuse

Galaxy Zoo: Exploring the Motivations of Citizen Science Volunteers

The Galaxy Zoo citizen science website invites anyone with an Internet connection to participate in research by classifying galaxies from the Sloan Digital Sky Survey. As of April 2009, more than 200,000 volunteers had made more than 100 million galaxy classifications. In this paper, we present results of a pilot study into the motivations and demographics of Galaxy Zoo volunteers, and define a technique to determine motivations from free responses that can be used in larger multiple-choice surveys with similar populations. Our categories form the basis for a future survey, with the goal of determining the prevalence of each motivation.Comment: 15 pages, 3 figure

Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface

Background. Sulfatide is known to chaperone insulin crystallization within the pancreatic beta cell, but it is not known if this results from sulfatide being integrated inside the crystal structure or by binding the surface of the crystal. With this study, we aimed to characterize the molecular mechanisms underlying the integral role for sulfatide in stabilizing insulin crystals prior to exocytosis. Methods. We cocrystallized human insulin in the presence of sulfatide and solved the structure by molecular replacement. Results. The crystal structure of insulin crystallized in the presence of sulfatide does not reveal ordered occupancy representing sulfatide in the crystal lattice, suggesting that sulfatide does not permeate the crystal lattice but exerts its stabilizing effect by alternative interactions such as on the external surface of insulin crystals. Conclusions. Sulfatide is known to stabilize insulin crystals, and we demonstrate here that in beta cells sulfatide is likely coating insulin crystals. However, there is no evidence for sulfatide to be built into the crystal lattice

Correlation Between Caregiver Reports of Physical Function and Performance-based Measures in a Cohort of Older Adults With Alzheimer Disease

The objectives of this report are to determine the association between performance-based measures of physical function with caregiver reports of physical function in older adults with Alzheimer disease (AD) and to examine whether those associations vary by the level of patients' cognitive functioning. Subjects included 180 patient-caregiver dyads who are enrolled in a clinical trial testing the impact of an occupational therapy intervention plus guideline-level care to delay functional decline among older adults with AD. The primary caregiver-reported measure is the Alzheimer's Disease Cooperative Study Group Activities of Daily Living Inventory (ADCS-ADL). Performance-based measures include the Short Physical Performance Battery and the Short Portable Sarcopenia Measure. Analysis of covariance (ANCOVA) models were used to determine the associations of each physical performance measure with ADCS-ADL, adjusting for cognition function and other covariates. We found significant correlations between caregiver reports and observed performance-based measures across all levels of cognitive function, with patients in the lowest cognitive group showing the highest correlation. These findings support the use of proxy reports to assess physical function among older adults with AD

Galaxy Zoo: Motivations of Citizen Scientists

Citizen science, in which volunteers work with professional scientists to conduct research, is expanding due to large online datasets. To plan projects, it is important to understand volunteers' motivations for participating. This paper analyzes results from an online survey of nearly 11,000 volunteers in Galaxy Zoo, an astronomy citizen science project. Results show that volunteers' primary motivation is a desire to contribute to scientific research. We encourage other citizen science projects to study the motivations of their volunteers, to see whether and how these results may be generalized to inform the field of citizen science.Comment: 41 pages, including 6 figures and one appendix. In press at Astronomy Education Revie

Orexin neurons track temporal features of blood glucose in behaving mice

Does the brain track how fast our blood glucose is changing? Knowing such a rate of change would enable the prediction of an upcoming state and a timelier response to this new state. Hypothalamic arousal-orchestrating hypocretin/orexin neurons (HONs) have been proposed to be glucose sensors, yet whether they track glucose concentration (proportional tracking) or rate of change (derivative tracking) is unknown. Using simultaneous recordings of HONs and blood glucose in behaving male mice, we found that maximal HON responses occur in considerable temporal anticipation (minutes) of glucose peaks due to derivative tracking. Analysis of >900 individual HONs revealed glucose tracking in most HONs (98%), with derivative and proportional trackers working in parallel, and many (65%) HONs multiplexed glucose and locomotion information. Finally, we found that HON activity is important for glucose-evoked locomotor suppression. These findings reveal a temporal dimension of brain glucose sensing and link neurobiological and algorithmic views of blood glucose perception in the brain's arousal orchestrators

Challenges of Cryptocurrencies Forensics – A Case Study of Investigating, Evidencing and Prosecuting Organised Cybercriminals

This article presents policing challenges of investigating, evidencing and prosecuting organized cybercriminals for the crimes committed using cryptocurrencies such as Bitcoin. A set of best practices is discussed to tackle these challenges in real world investigations. This work is a result of collaboration with a number of stakeholders the policing and judicial ecosystem with the objective of investigating and prosecuting the new generation of organised cybercriminals. Concrete scenarios of using Bitcoins in a range of cybercrimes were developed as part of this project and the devices were analysed to extract evidence to assist prosecution of organised cybercriminals. We have also presented our return of experience for various stages of digital forensics analysis of devices used in Bitcoin transactions

Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines

Ionising radiation is commonly used in the treatment of colorectal cancer. Tumour cells with mutant p53 undergo cell cycle arrest at G2/M after ionising radiation and evidence suggests that abrogation of this G2 arrest can lead to a premature, aberrant mitosis, thus enhancing ionising radiation-induced cell killing. The G2 checkpoint inhibitor UCN-01 was thus investigated to determine whether it would abrogate the G2 checkpoint induced by 5 Gy ionising radiation in a range of colorectal tumour cell lines. Data presented show that, at doses that are alone non-toxic to the cells, UCN-01 inhibits the ionising radiation-induced G2 checkpoint in five colorectal tumour cell lines with mutant p53. The ability of UCN-01 to sensitise cells to ionising radiation-induced growth inhibition and apoptosis was also investigated and UCN-01 was found to radiosensitise two out of five cell lines. These results were confirmed by long-term colony forming efficiency studies. These results demonstrate that abrogation of the ionising radiation-induced G2 checkpoint is not necessarily associated with sensitisation to ionising radiation, however, some colorectal tumour cell lines can be radiosensitised by UCN-01. Although the mechanism of radiosensitisation is not clear, this may still be an important treatment strategy