Formal Specifications and Analysis of the Computer Assisted Resuscitation Algorithm (CARA) Infusion Pump Control System

Reliability of medical devices such as the CARA Infusion Pump Control System is of extreme importance given that these devices are being used on patients in critical condition. The Infusion Pump Control System includes embedded processors and accompanying embedded software for monitoring as well as controlling sensors and actuators that allow the embedded systems to interact with their environments. This nature of the Infusion Pump Control System adds to the complexity of assuring the reliability of the total system. The traditional methods of developing embedded systems are inadequate for such safety-critical devices. In this paper, we study the application of formal methods to the requirements capture and analysis for the Infusion Pump Control System. Our approach consists of two phases. The first phase is to convert the informal design requirements into a set of reference specifications using a formal system, in this case EFSMs (Extended Finite State Machines). The second phase is to translate the reference specifications to the tools supporting formal analysis, such as SCR and Hermes. This allows us to conclude properties of the reference specifications. Our research goal is to develop a framework and methodology for the integrated use of formal methods in the development of embedded medical systems that require high assurance and confidence

Sensitive Probing of Exoplanetary Oxygen via Mid Infrared Collisional Absorption

The collision-induced fundamental vibration-rotation band at 6.4 um is the most significant absorption feature from O2 in the infrared (Timofeyev and Tonkov, 1978; Rinslandet al., 1982, 1989), yet it has not been previously incorporated into exoplanet spectral analyses for several reasons. Either CIAs were not included or incomplete/obsolete CIA databases were used. Also, the current version of HITRAN does not include CIAs at 6.4 um with other collision partners (O2-X). We include O2-X CIA features in our transmission spectroscopy simulations by parameterizing the 6.4 um O2-N2 CIA based on Rinsland et al.(1989) and the O2-CO2 CIA based on Baranov et al. (2004). Here we report that the O2-X CIA may be the most detectable O2 feature for transit observations. For a potentialTRAPPIST-1e analogue system within 5 pc of the Sun, it could be the only O2 detectable signature with JWST (using MIRI LRS) for a modern Earth-like cloudy atmosphere with biological quantities of O2. Also, we show that the 6.4 um O2-X CIA would be prominent for O2-rich desiccated atmospheres (Luger and Barnes, 2015) and could be detectable with JWST in just a few transits. For systems beyond 5 pc, this feature could therefore be a powerful discriminator of uninhabited planets with non-biological "false positive" O2 in their atmospheres - as they would only be detectable at those higher O2 pressures.Comment: Published in Nature Astronom

Habitable Moist Atmospheres on Terrestrial Planets near the Inner Edge of the Habitable Zone around M Dwarfs

Terrestrial planets in the habitable zones (HZs) of low-mass stars and cool dwarfs have received significant scrutiny recently because their shorter orbital periods increase their chances of detection and characterization compared to planets around G-dwarfs. As these planets are likely tidal-locked, improved 3D numerical simulations of such planetary atmospheres are needed to guide target selection. Here we use a 3-D climate system model, updated with new water-vapor absorption coefficients derived from the HITRAN 2012 database, to study ocean covered planets at the inner edge of the HZ around late-M to mid-K stars ($2600$ K <= Teff <= 4500K). Our results indicate that these updated water-vapor coefficients result in significant warming compared to previous studies, so the inner HZ around M-dwarfs is not as close as suggested by earlier work. Assuming synchronously rotating planets with background 1 bar N2 atmospheres, we find that planets at the inner HZ of stars with Teff > 3000K undergo the classical "moist-greenhouse" (H2O mixing ratio > 10-3 in the stratosphere) at significantly lower surface temperature (~ 280K) in our 3-D model compared with 1-D climate models (~ 340K). This implies that some planets around low mass stars can simultaneously undergo water-loss and remain habitable. However, for star with Teff <= 3000K, planets at the inner HZ may directly transition to a runaway state, while bypassing the moist greenhouse water-loss entirely. We analyze transmission spectra of planets in a moist green-house regime, and find that there are several prominent H2O features within JWST instruments range. Thus, relying only upon standard Earth-analog spectra with 24-hour rotation period around M-dwarfs for habitability studies will miss the strong H2O features that one would expect to see on synchronously rotating planets around M-dwarf stars, with JWST.Comment: Accepted to Astrophysical Journa

Surface and Temporal Biosignatures

Recent discoveries of potentially habitable exoplanets have ignited the prospect of spectroscopic investigations of exoplanet surfaces and atmospheres for signs of life. This chapter provides an overview of potential surface and temporal exoplanet biosignatures, reviewing Earth analogues and proposed applications based on observations and models. The vegetation red-edge (VRE) remains the most well-studied surface biosignature. Extensions of the VRE, spectral "edges" produced in part by photosynthetic or nonphotosynthetic pigments, may likewise present potential evidence of life. Polarization signatures have the capacity to discriminate between biotic and abiotic "edge" features in the face of false positives from band-gap generating material. Temporal biosignatures -- modulations in measurable quantities such as gas abundances (e.g., CO2), surface features, or emission of light (e.g., fluorescence, bioluminescence) that can be directly linked to the actions of a biosphere -- are in general less well studied than surface or gaseous biosignatures. However, remote observations of Earth's biosphere nonetheless provide proofs of concept for these techniques and are reviewed here. Surface and temporal biosignatures provide complementary information to gaseous biosignatures, and while likely more challenging to observe, would contribute information inaccessible from study of the time-averaged atmospheric composition alone.Comment: 26 pages, 9 figures, review to appear in Handbook of Exoplanets. Fixed figure conversion error

Introducing the “analogs for Venus’ geologically recent surfaces” initiative: an opportunity for identifying and analyzing recently active volcano-tectonic areas of Venus trough a comparative study with terrestrial analogs

Several missions to Venus have been recently selected for launch [1–6], opening a new era for the exploration of the planet. One of the key questions that the future missions need to address is whether Venus is presently volcanically active [7–15]. Studying areas of active volcanism and tectonism on Venus is crucial to reveal clues about the geologic past of the planet, as well as provide information about the volatile content of its interior and the formation of its dense atmosphere. The “Analogsfor VENus’ GEologically Recent Surfaces” (AVENGERS) initiative aims to build a comprehensive database of terrestrial analog sites for the comparative study of recent and possibly on- going volcanic activity on Venus. Besides its scientific relevance, the AVENG- ERS initiative also acts as a bridge for international scientific collaboration, including the leadership and/or team members from the currently selected missions to Venus