A correlation of optical, radio, and interplanetary records of solar events Final report

Correlation of optical, radio, and interplanetary records of solar event

Gator: a low-background counting facility at the Gran Sasso Underground Laboratory

A low-background germanium spectrometer has been installed and is being operated in an ultra-low background shield (the Gator facility) at the Gran Sasso underground laboratory in Italy (LNGS). With an integrated rate of ~0.16 events/min in the energy range between 100-2700 keV, the background is comparable to those of the world's most sensitive germanium detectors. After a detailed description of the facility, its background sources as well as the calibration and efficiency measurements are introduced. Two independent analysis methods are described and compared using examples from selected sample measurements. The Gator facility is used to screen materials for XENON, GERDA, and in the context of next-generation astroparticle physics facilities such as DARWIN.Comment: 14 pages, 6 figures, published versio

MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection.

Bacterial biofilms represent a significant therapeutic challenge based on their ability to evade host immune and antibiotic-mediated clearance. Recent studies have implicated IL-1β in biofilm containment, whereas Toll-like receptors (TLRs) had no effect. This is intriguing, since both the IL-1 receptor (IL-1R) and most TLRs impinge on MyD88-dependent signaling pathways, yet the role of this key adaptor in modulating the host response to biofilm growth is unknown. Therefore, we examined the course of S. aureus catheter-associated biofilm infection in MyD88 knockout (KO) mice. MyD88 KO animals displayed significantly increased bacterial burdens on catheters and surrounding tissues during early infection, which coincided with enhanced dissemination to the heart and kidney compared to wild type (WT) mice. The expression of several proinflammatory mediators, including IL-6, IFN-γ, and CXCL1 was significantly reduced in MyD88 KO mice, primarily at the later stages of infection. Interestingly, immunofluorescence staining of biofilm-infected tissues revealed increased fibrosis in MyD88 KO mice concomitant with enhanced recruitment of alternatively activated M2 macrophages. Taken in the context of previous studies with IL-1β, TLR2, and TLR9 KO mice, the current report reveals that MyD88 signaling is a major effector pathway regulating fibrosis and macrophage polarization during biofilm formation. Together these findings represent a novel example of the divergence between TLR and MyD88 action in the context of S. aureus biofilm infection

Switched Reluctance Motor Drives for Hybrid Electric Vehicles

Because of the ever‐increasing concerns on the energy utilization and environmental protection, the development of hybrid electric vehicles (HEVs) has become a hot research topic. As the major part of HEV technologies, the electric motor drives have to offer high efficiency, high power density, high controllability, wide‐speed operating range, and maintenance‐free operation. In particular, the switched reluctance (SR) motor drive can achieve most of these goals; therefore, this motor type has drawn much attention in the past. This chapter aims to serve as an overview of the latest developments of the SR motor drive, purposely for HEV applications. To be specific, the discussions on motor structures for torque density enhancement and torque ripple minimization are covered

Deteksi Transmisi Transovarial Virus Dengue Pada Aedes Aegypti Dengan Teknik Imunositokimia Di Kota Manado

: Capability of Dengue virus to maintain its existence by two mechanism, that is horizontal transmission between veremia vertebrata that contracted by Aedes mosquito and vertical transmission from female mosquito infective to next generation. The most mechanism common occurrence is vertical transmission whereabout of transovarial transmission can be detected by many kind of way, one of way is immunositochemical technic. Immunositochemical is reported to be able detect antigen Dengue virus in low level. This research aims to prove whereabout of transovarial transmission Dengue virus on Aedes aegypti in Manado city. Researche sampel is Aedes aegypti mosquitos from eggs Aedes aegypti that was taken from urban village that is DBD case. This research was held on November 2015 – January 2016. Research result show that Aedes aegypti mosquito antigen positive Dengue are 24 tail of mosquitos from 48 tail of mosquitos that was tested with Index Transmissi Transovarial (ITT) about 39,1% - 70%. Based on research result can be proven that there is transovarial transmission Dengue virus on Aedes aegypti in West Kombos Urban Village, Singkil Distric, Manado City

Architectural Model to Enable Power System Tradeoff Studies

We continue the development of an overall architectural model for an all-electric ship using a physics-based simulation environment to perform fully-integrated simulation of electrical, hydrodynamic, thermal, and structural components of the ship operating in a seaway. The goal of this architectural model is to develop an early-stage design tool capable of performing tradeoff studies on concepts such as AC vs. DC distribution, frequency and voltage level, inclusion of reduction gears, energy and power management options, and effect of arrangements and topology. The results of the studies will be presented in standard metrics including cost, weight, volume, efficiency/fuel consumption, reliability and survivability. We will specifically look at the hull, mechanical and electrical (HM&E) systems that support the ship and its missions; specifically, the electrical generation and distribution system, propulsion equipment, fresh- and saltwater pumping and distribution, control systems, and structural components

Design and Performance of the XENON10 Dark Matter Experiment

XENON10 is the first two-phase xenon time projection chamber (TPC) developed within the XENON dark matter search program. The TPC, with an active liquid xenon (LXe) mass of about 14 kg, was installed at the Gran Sasso underground laboratory (LNGS) in Italy, and operated for more than one year, with excellent stability and performance. Results from a dark matter search with XENON10 have been published elsewhere. In this paper, we summarize the design and performance of the detector and its subsystems, based on calibration data using sources of gamma-rays and neutrons as well as background and Monte Carlo simulations data. The results on the detector's energy threshold, energy and position resolution, and overall efficiency show a performance that exceeds design specifications, in view of the very low energy threshold achieved (<10 keVr) and the excellent energy resolution achieved by combining the ionization and scintillation signals, detected simultaneously

3D Position Sensitive XeTPC for Dark Matter Search

The technique to realize 3D position sensitivity in a two-phase xenon time projection chamber (XeTPC) for dark matter search is described. Results from a prototype detector (XENON3) are presented.Comment: Presented at the 7th UCLA Symposium on "Sources and Detection of Dark Matter and Dark Energy in the Universe

Basic kinetic wealth-exchange models: common features and open problems

We review the basic kinetic wealth-exchange models of Angle [J. Angle, Social Forces 65 (1986) 293; J. Math. Sociol. 26 (2002) 217], Bennati [E. Bennati, Rivista Internazionale di Scienze Economiche e Commerciali 35 (1988) 735], Chakraborti and Chakrabarti [A. Chakraborti, B. K. Chakrabarti, Eur. Phys. J. B 17 (2000) 167], and of Dragulescu and Yakovenko [A. Dragulescu, V. M. Yakovenko, Eur. Phys. J. B 17 (2000) 723]. Analytical fitting forms for the equilibrium wealth distributions are proposed. The influence of heterogeneity is investigated, the appearance of the fat tail in the wealth distribution and the relaxation to equilibrium are discussed. A unified reformulation of the models considered is suggested.Comment: Updated version; 9 pages, 5 figures, 2 table