35 research outputs found

    Spain

    Get PDF
    This chapter presents a review of the situation concerning the various geomorphological hazards in the country, including some information about existing programmes for research, control and mitigation. With its great variety of climatic, geological and morphodynamic environments, Spain is subject to every kind of natural hazard: tsunamis, floods, volcanism, and mass movements. The whole of the territory is prone to some kind of geomorphological hazard but it is in the eastern and southern coastal strips that the risks are greatest. One of the main problems for the mitigation of geomorphological hazards in Spain is the lack of an appropriate regulatory framework for the incorporation of natural hazard assessments into land-use planning and management at the macro-, meso- and micro-planning levels. The coverage of hazard mapping is still far from complete or adequate, and much work remains to be done. There has been considerable diversity in the methods used for risk assessment and for the cartographic representation of natural hazards. An urgent need is to establish common, accepted methodologies and criteria, based on indicators defined as clearly as possible, and to standardize map legends and scales for different planning levels. Information programmes for the general public also need to be considerably expanded

    The miniJPAS survey quasar selection IV: Classification and redshift estimation with SQUEzE

    Full text link
    We present a list of quasar candidates including photometric redshift estimates from the miniJPAS Data Release constructed using SQUEzE. This work is based on machine-learning classification of photometric data of quasar candidates using SQUEzE. It has the advantage that its classification procedure can be explained to some extent, making it less of a `black box' when compared with other classifiers. Another key advantage is that using user-defined metrics means the user has more control over the classification. While SQUEzE was designed for spectroscopic data, here we adapt it for multi-band photometric data, i.e. we treat multiple narrow-band filters as very low-resolution spectra. We train our models using specialized mocks from Queiroz et al. (2022). We estimate our redshift precision using the normalized median absolute deviation, σNMAD\sigma_{\rm NMAD} applied to our test sample. Our test sample returns an f1f_1 score (effectively the purity and completeness) of 0.49 for quasars down to magnitude r=24.3r=24.3 with z2.1z\geq2.1 and 0.24 for quasars with z<2.1z<2.1. For high-z quasars, this goes up to 0.9 for r<21.0r<21.0. We present two catalogues of quasar candidates including redshift estimates: 301 from point-like sources and 1049 when also including extended sources. We discuss the impact of including extended sources in our predictions (they are not included in the mocks), as well as the impact of changing the noise model of the mocks. We also give an explanation of SQUEzE reasoning. Our estimates for the redshift precision using the test sample indicate a σNMAD=0.92%\sigma_{NMAD}=0.92\% for the entire sample, reduced to 0.81\% for r<22.5r<22.5 and 0.74\% for r<21.3r<21.3. Spectroscopic follow-up of the candidates is required in order to confirm the validity of our findings.Comment: Accepted in A&A 24 pages, 24 figures, 7 table

    Amplified Genes May Be Overexpressed, Unchanged, or Downregulated in Cervical Cancer Cell Lines

    Get PDF
    Several copy number-altered regions (CNAs) have been identified in the genome of cervical cancer, notably, amplifications of 3q and 5p. However, the contribution of copy-number alterations to cervical carcinogenesis is unresolved because genome-wide there exists a lack of correlation between copy-number alterations and gene expression. In this study, we investigated whether CNAs in the cell lines CaLo, CaSki, HeLa, and SiHa were associated with changes in gene expression. On average, 19.2% of the cell-line genomes had CNAs. However, only 2.4% comprised minimal recurrent regions (MRRs) common to all the cell lines. Whereas 3q had limited common gains (13%), 5p was entirely duplicated recurrently. Genome-wide, only 15.6% of genes located in CNAs changed gene expression; in contrast, the rate in MRRs was up to 3 times this. Chr 5p was confirmed entirely amplified by FISH; however, maximum 33.5% of the explored genes in 5p were deregulated. In 3q, this rate was 13.4%. Even in 3q26, which had 5 MRRs and 38.7% recurrently gained SNPs, the rate was only 15.1%. Interestingly, up to 19% of deregulated genes in 5p and 73% in 3q26 were downregulated, suggesting additional factors were involved in gene repression. The deregulated genes in 3q and 5p occurred in clusters, suggesting local chromatin factors may also influence gene expression. In regions amplified discontinuously, downregulated genes increased steadily as the number of amplified SNPs increased (p<0.01, Spearman's correlation). Therefore, partial gene amplification may function in silencing gene expression. Additional genes in 1q, 3q and 5p could be involved in cervical carcinogenesis, specifically in apoptosis. These include PARP1 in 1q, TNFSF10 and ECT2 in 3q and CLPTM1L, AHRR, PDCD6, and DAP in 5p. Overall, gene expression and copy-number profiles reveal factors other than gene dosage, like epigenetic or chromatin domains, may influence gene expression within the entirely amplified genome segments

    IMPACT-Global Hip Fracture Audit: Nosocomial infection, risk prediction and prognostication, minimum reporting standards and global collaborative audit. Lessons from an international multicentre study of 7,090 patients conducted in 14 nations during the COVID-19 pandemic

    Get PDF

    TRY plant trait database – enhanced coverage and open access

    Get PDF
    Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives

    The excavation of buried articulated Neanderthal skeletons at Sima de las Palomas (Murcia, SE Spain)

    No full text
    At Sima de las Palomas del Cabezo Gordo (Murcia, Spain) remains of several Neanderthals have been excavated recently. From about 50,000 years ago articulated parts of 3 adult skeletons (including skulls with mandibles, vertebral column, rib cages, shoulder blades, hip bones, upper and lower limbs, hands and feet, often in anatomical connexion) were excavated from the lower part of a cemented accumulation of scree and large stones (éboulis) sloping downwards and inwards into the cavity, along with burnt bones of large mammals and Mousterian implements. The excavation of the skeletons is the subject of this paper (palaeoanthropological skeletal descriptions are soon to be published elsewhere). Behind the cemented scree there accumulated a layer of finer sediment containing burnt animal bones, followed by more fine sediment that filled the cavity up to the overhanging rock roof and contained isolated teeth and unburnt bone fragments of Neanderthals, including 3 mandibles, as well as Mousterian implements and faunal remains, all dating from before 40,000 years ago. Altogether, at least 9 Neanderthals are represented by finds from the site (including 3 unstratified mandibles), ranging from babies to adults. Dating methods include radiocarbon, uranium-series, and optical luminescence. Pollen analysis implies conditions less severe than those of the Heinrich 4 cold oscillation at 40,000 years ago

    An Experimental Analysis of Design Choices of Multi-objective Ant Colony Optimization Algorithms

    No full text
    There have been several proposals on how to apply the ant colony optimization (ACO) metaheuristic to multi-objective combinatorial optimization problems (MOCOPs). This paper proposes a new formulation of these multi-objective ant colony optimization (MOACO) algorithms. This formulation is based on adding specific algorithm components for tackling multiple objectives to the basic ACO metaheuristic. Examples of these components are how to represent multiple objectives using pheromone and heuristic information, how to select the best solutions for updating the pheromone information, and how to define and use weights to aggregate the different objectives. This formulation reveals more similarities than previously thought in the design choices made in existing MOACO algorithms. The main contribution of this paper is an experimental analysis of how particular design choices affect the quality and the shape of the Pareto front approximations generated by each MOACO algorithm. This study provides general guidelines to understand how MOACO algorithms work, and how to improve their design. © 2012 Springer Science + Business Media, LLC.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Relationship of Weather Types on the Seasonal and Spatial Variability of Rainfall, Runoff, and Sediment Yield in the Western Mediterranean Basin

    Get PDF
    Rainfall is the key factor to understand soil erosion processes, mechanisms, and rates. Most research was conducted to determine rainfall characteristics and their relationship with soil erosion (erosivity) but there is little information about how atmospheric patterns control soil losses, and this is important to enable sustainable environmental planning and risk prevention. We investigated the temporal and spatial variability of the relationships of rainfall, runoff, and sediment yield with atmospheric patterns (weather types, WTs) in the western Mediterranean basin. For this purpose, we analyzed a large database of rainfall events collected between 1985 and 2015 in 46 experimental plots and catchments with the aim to: (i) evaluate seasonal differences in the contribution of rainfall, runoff, and sediment yield produced by the WTs; and (ii) to analyze the seasonal efficiency of the different WTs (relation frequency and magnitude) related to rainfall, runoff, and sediment yield. The results indicate two different temporal patterns: the first weather type exhibits (during the cold period: autumn and winter) westerly flows that produce the highest rainfall, runoff, and sediment yield values throughout the territory; the second weather type exhibits easterly flows that predominate during the warm period (spring and summer) and it is located on the Mediterranean coast of the Iberian Peninsula. However, the cyclonic situations present high frequency throughout the whole year with a large influence extended around the western Mediterranean basin. Contrary, the anticyclonic situations, despite of its high frequency, do not contribute significantly to the total rainfall, runoff, and sediment (showing the lowest efficiency) because of atmospheric stability that currently characterize this atmospheric pattern. Our approach helps to better understand the relationship of WTs on the seasonal and spatial variability of rainfall, runoff and sediment yield with a regional scale based on the large dataset and number of soil erosion experimental stations.Spanish Government (Ministry of Economy and Competitiveness, MINECO) and FEDER Projects: CGL2014 52135-C3-3-R, ESP2017-89463-C3-3-R, CGL2014-59946-R, CGL2015-65569-R, CGL2015-64284-C2-2-R, CGL2015-64284-C2-1-R, CGL2016-78075-P, GL2008-02879/BTE, LEDDRA 243857, RECARE-FP7, CGL2017-83866-C3-1-R, and PCIN-2017-061/AEI. Dhais Peña-Angulo received a “Juan de la Cierva” postdoctoral contract (FJCI-2017-33652 Spanish Ministry of Economy and Competitiveness, MEC). Ana Lucia acknowledge the "Brigitte-Schlieben-Lange-Programm". The “Geoenvironmental Processes and Global Change” (E02_17R) was financed by the Aragón Government and the European Social Fund. José Andrés López-Tarazón acknowledges the Secretariat for Universities and Research of the Department of the Economy and Knowledge of the Autonomous Government of Catalonia for supporting the Consolidated Research Group 2014 SGR 645 (RIUS- Fluvial Dynamics Research Group). Artemi Cerdà thank the funding of the OCDE TAD/CRP JA00088807. José Martínez-Fernandez acknowledges the project Unidad de Excelencia CLU-2018-04 co-funded by FEDER and Castilla y León Government. Ane Zabaleta is supported by the Hydro-Environmental Processes consolidated research group (IT1029-16, Basque Government). This paper has the benefit of the Lab and Field Data Pool created within the framework of the COST action CONNECTEUR (ES1306)

    La vigilancia de la salud de los trabajadores expuestos al amianto: ejemplo de colaboración entre el Sistema de Prevención de Riesgos Laborales y el sistema Nacional de Salud

    No full text
    El Ministerio de Sanidad y Consumo y las Comunidades Autónomas han diseñado y consensuado con los profesionales sanitarios y las organizaciones empresariales y sindicales representativas un Plan Integral de Vigilancia de la Salud de los Trabajadores que han estado expuestos a Amianto, con el objetivo de garantizar una intervención adecuada, uniforme y armonizada de estos trabajadores en todo el territorio nacional. La elaboración del Programa partió del Grupo de Trabajo de Salud Laboral del Consejo Interterritorial, se enriqueció con las aportaciones del Grupo de Trabajo Amianto de la Comisión Nacional de Seguridad y Salud en el Trabajo, fue consensuado con los profesionales de la medicina y enfermería del trabajo, y fue aprobado por las autoridades sanitarias y laborales. El Programa consta de siete grandes bloques de actividades. Dos años después de aprobado el Programa, el estado de implantación en las Comunidades Autónomas es desigual. Las principales dificultades para su puesta en marcha se encuentran en la elaboración del Registro de expuestos. Un total de 5.778 trabajadores están incluidos en el Registro. 208 trabajadores tienen EPOC, 198 alteraciones pleurales benignas, 8 cáncer de pulmón, 10 mesotelioma y 7 presentan otros cánceres con posible relación con el amianto (gástrico, de laringe y colon)
    corecore