Efficient multitemporal change detection techniques for hyperspectral images on GPU

Hyperspectral images contain hundreds of reflectance values for each pixel. Detecting regions of change in multiple hyperspectral images of the same scene taken at different times is of widespread interest for a large number of applications. For remote sensing, in particular, a very common application is land-cover analysis. The high dimensionality of the hyperspectral images makes the development of computationally efficient processing schemes critical. This thesis focuses on the development of change detection approaches at object level, based on supervised direct multidate classification, for hyperspectral datasets. The proposed approaches improve the accuracy of current state of the art algorithms and their projection onto Graphics Processing Units (GPUs) allows their execution in real-time scenarios

PBMC-Derived T Cells

This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License.T cell cultures are a valuable tool in food research to perform studies within the food allergy field. Their main applications aim to analyze immunological responses towards food protein antigens to gain further insights into the mechanisms responsible for the development of oral tolerance or for the triggering of food allergies. This chapter describes the main applications, isolation techniques, and culture conditions for PBMC-derived T cells. Furthermore, critical parameters of the model, together with the experimental read outs will be discussed.This work was funded by the project AGL2011-24740. D. L.-O. was the recipient of a FPU fellowship from the Spanish Ministry of Education, Culture and Sports. I. L.-E. acknowledges the financial support of CSIC through a JAE Doc grant.Peer Reviewe

Clasificación de imágenes de superficie terrestre mediante técnicas basadas en ELM

Traballo Fin de Máster en Tecnoloxías da Información. Curso 2013-2014Los algoritmos de procesado de im agenes, en general, y los algoritmos de procesado de im agenes hiperespectrales, en particular, son computacionalmente muy costosos, lo que los convierte en buenos candidatos para el modelo SIMD de procesamiento en GPU. En este trabajo se presenta una implementaci on e cente en GPU para un esquema de clasi caci on espectral-espacial de im agenes hiperespectrales. El procesado espacial est a basado en una transformaci on divisioria por inundaci on (Watershed ) aplicada despu es de reducir la im agen hiperespectral a una unica banda mediante un gradiente morfol ogico. La clasi caci on hiperespectral es provista por una t ecnica basada en ELM (Extreme Learning Machine). ELM puede ser expresado en t erminos de operaciones matriciales de forma que pueda sacar el m aximo provecho de la arquitectura de las GPU obeniendo resultados competitivos en comparaci on con una estrategia tradicional basada en SVM en cuanto a precisi on con unos tiempos de ejecuci on signi cativamente menores. Para mejorar los resultados de ELM, se aplica un algoritmo de regularizaci on espacial y, adem as, tambi en se considera el uso de agrupaciones de ELMs. Para obtener el resultado nal de la clasi caci on espectral-espacial se aplica un algoritmo adaptativo de voto de la mayor a a los resultados previamente obtenidos. Los resultados obtenidos en este trabajo muestran que ELM es un clasi cador adecuado para su uso en el procesado de im agenes hiperespectrales en GPU, puesto que, para todas las con guraciones tanto espectrales como espectralesespaciales desarrolladas, obtiene resultados de precisi on competitivos con los obtenidos por un clasi cador SVM, ampliamente utilizado en este ambito, con tiempos de ejecuci on notablemente inferiore

Efectos de un programa piloto de musicoterapia basado en la composición de canciones sobre los niveles de depresión en adultos mayores con deterioro cognitivo residentes de un hogar geriátrico privado de la ciudad de Bogotá

La presente investigación buscó describir y analizar los efectos de la implementación de un programa de musicoterapia basado en la composición de canciones en los niveles de depresión de un grupo de adultos mayores institucionalizados. Se emplearon herramientas teóricas de la composición de canciones de Baker y Wigram (2005) así como del Abordaje Plurimodal diseñado por Diego Shapira (2007). Se escogió un diseño de estudio de caso de grupo cualitativo descriptivo, con seis personas participantes pertenecientes al centro de atención integral para el adulto mayor Ancestros de la ciudad de Bogotá. A partir de los diarios de campo, de los resultados de las pruebas estandarizadas y del análisis de las composiciones se presentan los resultados y su análisis a partir de 3 categorías: Depresión, Grupo Musicoterapéutico y Expresión Emocional, con 3 subcategorias: expresión emocional verbal, expresión emocional no verbal y expresión emocional musical- composición. Se concluyó que el programa de musicoterapia implementado a partir de la composición de canciones favoreció la expresión emocional de los usuarios generando efectos positivos especialmente en los síntomas afectivos presentes en los episodios depresivos, y cambios relacionados con la frecuencia de síntomas como llanto, decaimiento, infelicidad, anhedonia, percepción de vacío, entre otros indicadores de depresión, evidenciados en la disminución de los puntajes de depresión posteriores a la implementación del programa.Abstract: The present research sought to describe and analyze the effects of the implementation of a music therapy program based on songwriting in the depression levels of a group of institutionalized older adults. Theoretical tools of Songwriting by Baker and Wigram (2005) were used, as well as the Plurimodal Approach designed by Diego Shapira (2007). A descriptive qualitative group case study design was chosen, with six participants from the integral center for the elderly “Ancestros” of the city of Bogotá. From the field journals, the results of the standardized tests and the analysis of the compositi ons, the results and their analysis are presented from 3 categories: Depression, Music Therapy Group and Emotional Expression, with 3 subcategories: verbal emotional expression, non - verbal emotional expression and musical emotional expression - composition . It was concluded that the music therapy program implemented from songwriting favored the emotional expression of the users generating positive effects especially in the affective symptoms present in the depressive episodes, and changes related to the fre quency of symptoms such as crying, decay, unhappiness, anhedonia, perception of emptiness, among other depression indicators, evidenced in the decrease of depression scores after the implementation of the program.Maestrí

Oral immunotherapy be heated ovomuciod-reduced egg white in a Balb/C mouse model

Resumen del trabajo presentado al Food Allergy and Anaphylaxis Meeting (FAAM-2011) celebrado en Venecia.Peer Reviewe

Effectiveness of a Chess-Training Program for Improving Cognition, Mood, and Quality of Life in Older Adults: A Pilot Study

Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG[Abstract] Background. Regular practice of a cognitively stimulating activity, such as chess, can help maintain a healthy cognitive, social, and psychological state during the aging process. Objective. To evaluate the effects of a chess-training program on cognitive status, mood, and quality of life (QoL) in a sample of institutionalized and semi-institutionalized older adults. Method. A nonrandomized, controlled pilot study with repeated measures (pre- and post-intervention) was conducted. Results. Analyses revealed a positive impact of the chess program on general cognitive status (p < 0.001) and promising evidence (p < 0.043) of an impact on attention, processing speed, and executive functions. The participants in the intervention group also showed significant improvement in QoL scores (p < 0.021). Conclusions. A 12-week chess-training protocol with two 60-minute sessions per week improved cognition and QoL in a sample of institutionalized and semi-institutionalized older adults. Further research with larger samples is needed to explore its effects in depth.Xunta de Galicia; ED431C 2017/49Xunta de Galicia; ED431F 2017/09This work was supported by Xunta de Galicia (ED431C 2017/49, ED431F 2017/09). Laura Lorenzo-López is supported by the “Ramon y Cajal” Postdoctoral Senior Grant (RYC-2015-18394) from the Spanish Ministry of Economy, Industry, and Competitiveness, co-financed by the European Social Fund. Julia Blanco-Fandiño is supported by a pre-doctoral grant from the Autonomous Government of Galicia (ED481A-2017/219). Funding for open access charge: Universidade da Coruña/CISU

Clinical and Neuropsychological Correlates of Prefrailty Syndrome

[Abstract] Physical frailty is closely associated with cognitive impairment. We aim to investigate the neuropsychological profiles of prefrail and non-frail dementia-free community-dwelling older adults using a comprehensive neuropsychological evaluation, and to examine the association between specific frailty criteria and clinical and neuropsychological scores. Participants completed a comprehensive standardized neuropsychological evaluation (covering cognitive domains such as memory, executive functions, language and attention), and frailty assessment. Frailty was assessed according to biological criteria: unintentional weight loss, exhaustion, low physical activity, slowness, and weakness. The sample comprised 60 dementia-free community-dwelling adults, aged 65 years or older (range 65–89 years; 60.0% women). Forty-two participants were classified as robust (no frailty criteria present), and 18 as prefrail (1 or 2 frailty criteria present). We explored neurocognitive differences between the groups and examined the association between specific criteria of frailty phenotype and clinical and neuropsychological outcomes with bivariate tests and multivariate models. Prefrail participants showed poorer cognitive performance than non-frail participants in both memory and non-memory cognitive domains. However, delayed episodic memory was the only cognitive subdomain that remained significant after controlling for age, gender, and educational level. Gait speed was significantly associated with general cognitive performance, immediatememory, and processing speed, while grip strength was associated with visual episodic memory and visuoconstructive abilities. Both gait speed and grip strength were negatively associated with depressive scores. Our results suggest that prefrailty is associated with cognitive dysfunction. The fact that specific cognitive domains may be susceptible to subclinical states of physical frailty may have important clinical implications. Indeed, early detection of specific cognitive dysfunctions may allow opportunities for reversibility.Xunta de Galicia; ED431C 2017/49Xunta de Galicia; ED431F 2017/0

Palladium-Catalyzed Conjugate Addition of Terminal Alkynes to Enones

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Chemical Biology, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see: https://pubs.acs.org/doi/10.1021/ol300988nA practical protocol for the hydroalkynylation of enones using Pd catalysis is reported. The reaction proceeds efficiently with a variety of alkynes as well as with several cyclic and acyclic enones, providing synthetically relevant β-alkynyl ketones in good to excellent yieldsThis work was supported by the Spanish MINECO [SAF2007-61015, SAF2010-20822-C02, Consolider Ingenio 2010 CSD2007-00006], the ERDF and the Xunta de Galicia INCITE09209084PR, GRC2010/12. L.V. and R.G.-F. thank the Spanish MEC and MINECO for an FPU fellowship and a Juan de la Cierva contract, respectivelyS

In vitro digestibility and allergenicity of emulsified hen egg

Whole hen egg produced a fine stable O/W emulsion. The presence of egg proteins as part of the emulsion did not change their IgE binding, but it slightly increased the digestibility of the main allergens present in the egg-white. The observation that egg white proteins, forming part of an emulsion system did not become a much more effective substrate for pepsin indicates that, in the case of egg white proteins, there were not adsorption-induced changes that would considerably increase their flexibility and proteinase susceptibility.The increased digestibility of the emulsion resulted in a slightly lower IgE-binding capacity of the in vitro gastric and duodenal digests compared to those obtained from the egg in solution.Fil: Jiménez Saiz, Rodrigo. Consejo Superior de Investigaciones Científicas; EspañaFil: Pizones Ruiz Henestrosa, Víctor Manuel. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: López Fandiño, Rosina. Consejo Superior de Investigaciones Científicas; EspañaFil: Molina, Elena. Consejo Superior de Investigaciones Científicas; Españ

Relaciones existentes entre los parámetros físico-mecánicos clásicos en taludes compuestos por cenizas volcánicas, y las variaciones climáticas en períodos cortos (6 meses) y períodos largos (12 ó más meses), que puedan considerarse como un condicionador de las propiedades y estabilidad geotécnica de los suelos

CD-T 624.151 36 F212; 223 pParametrizar de manera periódica el comportamiento mecánico de los suelos compuestos por cenizas volcánicas y poder, a partir de la medición y obtención de algunos parámetros físico-mecánicos, establecer un modelo geotécnico predictivo dela ocurrencia de fenómenos de remoción en masa que pueda aplicarse en el territorio municipal por parte de las entidades que conforman el sistema municipal para la prevención y atención de desastres de Pereira.Universidad Libre Seccional Pereir