187 research outputs found
La conquista de Antequera, con la Leyenda de la Peña de los Enamorados
Copia digital : Diputación de Málaga. Biblioteca Canovas del Castillo, 201
Intervención del maestro Juan de Rueda Alcántara en las obras del Genil y Darro
En el recíproco juego de nombre y de fama que, desde tiempo inmemorial, Granada y sus ríos se Yienen haciendo, compartieron por igual las ventajas, la una y los otros. No sucedió lo mismo en orden al beneficio material que mutuamente pudieran prestarse. Ni con líricas tendechas, ni con restricciones a sus libertades, al ponerse en contacto con ella, ha podido la ciudad modificar la fisonomía ele sus ríos, de temperamento un tanto irregular y de biografía, todo lo poética que se qtüera en literatura, pero demasiado llena de episodios desgraciados y costosos en la realidad de sus personalidades
José Mayquez, empresario de la Casa Teatro de Granada en 1802
La casualidad de coincidir los apellidos de ambos, hace que, al nombrar a José Máyquez, actuando en Granada, acuda a nuestra mente el recuerdo del l sidoro del mismo apellido, el célebre trágico de nuestro teatro del siglo XIX. Pero, ni esto, ni el haber sido los dos vecinos de Granada, uno en 1802, como empresario de la Casa Teatro, y el otro desterrado de Madrid y huésped del escribano Antonio González, hasta su muerte, ocurrida el 18 de Mayo ele 1820, son pruebas suficientes del parentesco entre ambos, pese también a la afinidad ele gustos. y profesión. Es mucha la diferencia ele años que media entre la fecha en que José Máyquez manejaba los negocios de las compañías cómicas en Granada, y aquella en que, por nq querer representar una comedia de Javier de Durgos, fué enviado a esta ciudad Isidoro
La ciudad doliente y el motivo del homo sacer. Acercamiento a 2666, de Roberto Bolaño
págs.: 183-197Capítulo incluido en el libro: El feminicidio de Ciudad Juárez. Repercusiones legales y culturales de la impunidad. Salvador Bernabéu Albert y Carmen Mena García (Coords.). Sevilla: Universidad Internacional de Andalucía, 2015. ISBN 978-84-7993-271-8. Enlace: http://hdl.handle.net/10334/365
2007 : el año del Sol
Sumario : La estrella imprescindible.--
Pero, ¿cómo medimos el campo magnético?.--
El interior de las manchas solares.--
CIENCIA: PILARES E INCERTIDUMBRES.--
DECONSTRUCCIÓN Y otros ENSAYOS :
El satélite que indagará en el campo magnético solar.--
ACTUALIDAD.--
ENTRE BASTIDORES.--
HISTORIAS DE ASTRONOMÍA :
Una predicción, un cristal, un derrumbe y un incendio.--
HOMENAJE A LUCAS LARA.--
ACTIVIDADES IAA.--
El increíble y asombroso viaje de Fotón.Esta revista se publica con la ayuda de la Acción Complementaria CCT005-06-00178 del Programa Nacional de Fomento de la Cultura Científica y Tecnológica.N
La huella de carbono de la Universidad de Córdoba. 2013
La huella de carbono es un término usado para describir la cantidad de gases de efecto invernadero (GEI) que son liberados a la atmósfera directa o indirectamente como consecuencia de una actividad determinada, bien sea la fabricación de un producto, la prestación de un servicio, o el funcionamiento de una organización. Con el concepto huella de carbono de una organización se pretende describir el impacto total que una organización tiene sobre el clima en relación a las emisiones de GEI a la atmósfera. La utilización de la huella de carbono se ha ido desarrollando también como un elemento de información para comunicar el desempeño ambiental de una entidad a todas sus partes interesadas. Además de como indicador para tomar decisiones a la hora de reducir las emisiones asociadas a una actividad. Existen diversas metodologías para la identificación, cuantificación y comunicación de emisiones de GEI de organizaciones. Los documentos que constituyen las referencias más importantes en esta materia son las normas ISO 14064 y 14069, junto con el GHG Protocol, del World Resources Institute y el World Business Council for Sustainable Development
Influence of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Vitro and their Role in Ageing
[Abstract]
Introduction: This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced
ageing and pluripotency markers in cell cultures where they are added.
Methods: MSC-derived extracellular vesicles from old and young rat bone marrows were isolated by
ultracentrifugation and were characterised by western blotting, nanoparticle tracking analysis (NTA) and
transmission electron microscopy (TEM). They were added to young and old MSC cultures. Real-time quantitative
reverse transcription polymerase chain reactions and western blot analysis were performed to check the markers of
ageing (vinculin and lamin A), pluripotency markers (Nanog and Oct4) and components of the mTOR signalling
pathway (Rictor, Raptor, AKT and mTOR) in these cell populations. Subsequently, microRNA (miR)-188-3p expression
was transiently inhibited in young MSCs to demonstrate the influence of mTOR2 on MSC ageing.
Results: Incubation with young MSC-derived extracellular vesicles decreased the levels of ageing markers and
components of the mTOR pathway and increased the pluripotency markers from old MSC populations. By contrast,
incubation of young MSCs with old MSC-derived extracellular vesicles generated the reverse effects. Inhibition of
miR-188-3p expression in young MSCs produced extracellular vesicles that when incubated with old MSCs
produced an increase in the levels of Rictor, as well as a decrease of phosphor-AKT, as indicated by a significant
decrease in beta-galactosidase staining.
Conclusions: MSC-derived extracellular vesicles affected the behaviour of MSC cultures, based on their
composition, which could be modified in vitro. These experiments represented the basis for the development of
new therapies against ageing-associated diseases using MSC-derived extracellular vesicles.JAF-L is the recipient of a postdoctoral fellowship funded by Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia (Spain
Combining Management, Education and Participation for the Transformation of Universities towards Sustainability: The Trébol Programme
This article presents the design and development of the ‘Trébol (Clover) Programme’, a tool which allows us to improve environmental sustainability in the university environment by reinforcing the education, awareness, and training of its members. The system for certifying ‘good practice’ is divided into four progressive levels, and a certificate is awarded in order to demonstrate the environmental commitment acquired to third parties. The aim of the whole process is to create a practical forum for participation, communication, motivation and competence, which is necessary to foster effective pro-environmental behaviour. The study took place at the University of Córdoba (Spain), and, since it began in the 2013/2014 academic year, over 50 groups a wide range of areas have taken part, making a total of nearly 600 participants. The results show that the Trébol Programme enables environmental commitment to be put into practice, through continuous, systematised, participative and well-organised improvements in environmental performance. Its potential as an educational resource for environmental improvement should also be noted, by boosting environmental awareness and establishing new norms. It fits in well with the principles and areas of action of Education for Sustainable Development, and can be applied to universities and other settings to bring about a shift towards sustainability in the fields of teaching, research and management
The use of antidotes for calcium gluconate extravasation: an experimental study in mice
[Abstract] Background: Calcium gluconate extravasation is a process that can cause serious lesions, such as necrosis and calcification of the soft tissues. The aim of the present study was to analyze the beneficial effects of four possible local antidotes for calcium gluconate extravasation: hyaluronidase, sodium thiosulfate, triamcinolone acetonide, and physiologic saline solution.
Methods: Seventy-four BALB/c mice were used in the study. The substances selected for use in this study were calcium gluconate (4.6 mEq/ml), hyaluronidase (1500 IU/ml), sodium thiosulfate (25%), triamcinolone acetonide (40 mg/ml 0.5 mg/kg), and saline solution 0.9%. Five minutes were allowed to lapse after the calcium gluconate infiltration, and then an antidote was infiltrated. After 3 weeks, a skin biopsy was performed and a radiographic and histologic study was carried out.
Results: Only in the group infiltrated with sodium thiosulfate did all skin lesions disappear after the 3-week period after infiltration. In the radiographic study, calcium deposits larger than 0.5 mm were observed in 40 percent of cases without an antidote, in 33 percent with triamcinolone acetonide, in 13 percent with a saline solution, and in none with thiosulfate and hyaluronidase. In the histologic study, calcium deposits were found in 53 percent of cases without antidote, 100 percent of cases with triamcinolone acetonide, 33 percent of cases with saline solution, and 13 percent of cases with sodium thiosulfate or hyaluronidase.
Conclusion: Sodium thiosulfate and hyaluronidase prevent the development of calcium deposits after calcium gluconate extravasation
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