Metals and metallurgy in Phoenician Abdera. Isotopic data for the provenance and exchange of raw material

Se presentan los primeros resultados de análisis isotópicos llevados a cabo a una selección de muestras de galena, goterones de plomo y objetos de base cobre del asentamiento fenicio de Abdera (Adra, Almería). Según los datos de isótopos de plomo, se pueden distinguir dos zonas diferentes de aprovisionamiento de mineral, Sierra de Gádor y la Cuenca de Vera (posiblemente Cerro Minado o Herrerías), todas ellas zonas mineras de la actual provincia de Almería (España). Los resultados ponen de relieve aspectos inéditos de gran interés sobre el comercio de metales entre los fenicios occidentales.Proyecto HAR2010-21105-C02-02Peer reviewe

Automatic detection of relationships between banking operations using machine learning

In their daily business, bank branches should register their operations with several systems in order to share information with other branches and to have a central repository of records. In this way, information can be analysed and processed according to different requisites: fraud detection, accounting or legal requirements. Within this context, there is increasing use of big data and artificial intelligence techniques to improve customer experience. Our research focuses on detecting matches between bank operation records by means of applied intelligence techniques in a big data environment and business intelligence analytics. The business analytics function allows relationships to be established and comparisons to be made between variables from the bank's daily business. Finally, the results obtained show that the framework is able to detect relationships between banking operation records, starting from not homogeneous information and taking into account the large volume of data involved in the process. (C) 2019 Elsevier Inc. All rights reserved.This work was supported by the Research Program of the Ministry of Economy and Competitiveness - Government of Spain, (DeepEMR project TIN2017-87548-C2-1-R)

Perpendicular magnetic anisotropy in Nd-Co alloy films nanostructured by di-block copolymer templates

Nd-Co amorphous magnetic films with perpendicular magnetic anisotropy have been grown on nanostructured templates prepared with self-organized di-block poly(styrene)-block-poly(4-vinylpyridine) copolymer layers with a periodic structure of 60 nm spaced pores. These templates modify both the magnetic film topography and mechanical strain on a local scale. The effect of these structural changes is particularly noticeable in the low thickness range of the magnetic films where the transition from in-plane to out-of plane magnetization takes place. The Nd-Co films grown on the copolymer template present lower perpendicular magnetic anisotropy and, also, stronger stripe domain pinning effects in comparison with reference films grown on flat Si substrates

About the interaction between a laser beam and group IV nanowires: a study of the electromagnetic field enhancement in homogeneous and heterostructured nanowires

The optical properties of semiconductor nanowires (NWs) are object of study because they are the building blocks of the future nanophotonic devices. The high refractive index and its reduced dimension, make them suitable for photon engineering. The study of the interaction between NWs and visible light has revealed resonances of the light absorption/scattering by the NWs. Micro-Raman spectroscopy is used as a characterization method of semiconductor NWs. The relation between the Raman intensity and the incident electromagnetic (EM) field permits to study the light/NW interaction through the micro-Raman spectra of individual NWs. As compared to either metallic or dielectric NWs, the semiconductor NWs add additional tools to modify its interaction with light, for example, the composition, the presence of heterostructures, both axial and radial, doping, and the surface morphology. One presents herein a study of the optical response of group IV semiconductor NWs to visible photons. The study is experimentally carried out through the micro-Raman spectroscopy of different group IV NWs, both homogeneous and heterostructured (SiGe/Si), and the results are analyzed in terms of the EM modeling of the light/NW interaction using finite element methods (FEMs). The heterostructures are seen to produce additional resonances allowing new photonic capacities to the semiconductor NWs.Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref VA293U13

Ultrasmall superparamagnetic iron oxide particles for biomedical applications

Las partículas superparamagnéticas ultrapequeñas de óxido de hierro (USPIO) tienen una enorme utilidad en Biomedicina como agentes de contraste en resonancia magnética de imagen o como sistemas transportadores de fármacos, entre otras aplicaciones. La naturaleza del recubrimiento de los núcleos inorgánicos de las partículas USPIO determina su estabilidad in vitro y su comportamiento in vivo, siendo especialmente importantes sus propiedades fi sicoquímicas, en concreto el tamaño, la carga superfi cial y la densidad del recubrimiento. Las pequeñas dimensiones de las partículas USPIO hace difícil una caracterización fi sicoquímica completa, la cuál es de suma importancia para poder mejorar su estabilidad y comportamiento in vivo. Esta revisión se centra en las técnicas instrumentales utilizadas en el análisis de los núcleos magnéticos y de sus recubrimientos orgánicos.Ultrasmall superparamagnetic iron oxide (USPIO) particles are iron oxide nanoparticles currently used for Biomedical applications: contrast agents in magnetic resonance imaging, drug delivery systems, etc. The coatings surrounding the USPIO inorganic core may control the in vitro stability and the in vivo fate. Different physicochemical properties such as the fi nal size, the surface charge and the density of coverage are key factors in this respect. A complete physicochemical characterization of USPIOs particles is diffi cult due to their small dimensions. However, such a characterization is necessary to improve the stability of the particles and their in vivo behaviour. This review is focused on the techniques which can be applied to have a better insight in the magnetic core structure of these particles and their organic surface

Sub-Sync: automatic synchronization of subtitles in the broadcasting of true live programs in spanish

Individuals With Sensory Impairment (Hearing Or Visual) Encounter Serious Communication Barriers Within Society And The World Around Them. These Barriers Hinder The Communication Process And Make Access To Information An Obstacle They Must Overcome On A Daily Basis. In This Context, One Of The Most Common Complaints Made By The Television (Tv) Users With Sensory Impairment Is The Lack Of Synchronism Between Audio And Subtitles In Some Types Of Programs. In Addition, Synchronization Remains One Of The Most Significant Factors In Audience Perception Of Quality In Live-Originated Tv Subtitles For The Deaf And Hard Of Hearing. This Paper Introduces The Sub-Sync Framework Intended For Use In Automatic Synchronization Of Audio-Visual Contents And Subtitles, Taking Advantage Of Current Well-Known Techniques Used In Symbol Sequences Alignment. In This Particular Case, These Symbol Sequences Are The Subtitles Produced By The Broadcaster Subtitling System And The Word Flow Generated By An Automatic Speech Recognizing The Procedure. The Goal Of Sub-Sync Is To Address The Lack Of Synchronism That Occurs In The Subtitles When Produced During The Broadcast Of Live Tv Programs Or Other Programs That Have Some Improvised Parts. Furthermore, It Also Aims To Resolve The Problematic Interphase Of Synchronized And Unsynchronized Parts Of Mixed Type Programs. In Addition, The Framework Is Able To Synchronize The Subtitles Even When They Do Not Correspond Literally To The Original Audio And/Or The Audio Cannot Be Completely Transcribed By An Automatic Process. Sub-Sync Has Been Successfully Tested In Different Live Broadcasts, Including Mixed Programs, In Which The Synchronized Parts (Recorded, Scripted) Are Interspersed With Desynchronized (Improvised) Ones

Review of the “state of the art” and possibilities of the most significant approaches to the specific delivery of chemotherapy agents to tumor cells

Los principales problemas de la quimioterapia proceden esencialmente de la relativa falta de especificidad derivada de la extensa biodistribución de los agentes antitumorales y de los efectos secundarios generados por la acción inespecífica de éstos en tejidos y órganos sanos. La necesidad de encontrar tratamientos eficaces contra el cáncer ha hecho que se incrementen las líneas de investigación en esta materia. Una de las aproximaciones más prometedoras en este sentido es el desarrollo de sistemas coloidales biodegradables para el transporte de fármacos antitumorales. Gracias a éstos, se logra acumular específicamente la cantidad de fármaco administrada en el lugar de acción, logrando así un aumento significativo de la eficacia clínica, junto con una minimización de las reacciones adversas asociadas. En este trabajo, pretendemos analizar el estado actual en el diseño de coloides como transportadores de fármacos antitumorales, junto con la aplicación de las novedosas estrategias de transporte pasivo y activo de fármacos.The main problems related to chemotherapy mainly come from a relative lack of selectivity, that is associated to the extensive biodistribution of antitumor molecules, and to the severe side effects generated by the unspecific drug action on healthy tissues and organs. The need of finding out efficient treatments against cancer has led to an enhancement in the number of research lines in the field. In this way, one of the most promising approaches is the development of biodegradable colloids for the delivery of antitumor drugs. Thanks to them, it is possible to specifically concentrate the drug into the site of action. Therefore, a significant improvement of the chemotherapy effect is obtained along with a minimization of the related adverse side effects. In this review, we analyze the current “state of the art” in the development of colloidal systems for the efficient delivery of anticancer drugs. The possibilities of novel drug delivery strategies based on passive and active targeting mechanisms are also discussed

Konkurentnost intelektualnog kapitala gradova pokrajine Castilla-La Mancha u usporedbi s drugim španjolskim gradovima

Intellectual capital plays a central role in smart cities. The aim of this paper is to apply the recently developed model based on intellectual capital to measure and manage cities\u27 competitiveness. This model is applied to cities in Castilla-La Mancha and another 19 Spanish cities, enabling a comparative analysis between these cities. To this end, the study presents a synthetic indicator that allows us to rank Spanish cities based on available information and propose a comprehensive management strategy that addresses both tangible and intangible competitiveness. From the results, it can be concluded that the cities of Castilla-La Mancha feature excellent human capacities and a good quality of life but that there is room for improvement in terms of city infrastructure and planning.Intelektualni kapital ima središnju ulogu u pametnim gradovima. Cilj je ovoga rada primijeniti nedavno razvijeni model utemeljen na intelektualnom kapitalu u mjerenju konkurentnosti gradova i u upravljanju njihovim materijalnim i nematerijalnim bogatstvom. Model je primijenjen u gradovima pokrajine Castilla-La Mancha i u još 19 španjolskih gradova, omogućujući njihovu usporednu analizu. U tom smislu studija je sintetički pokazatelj koji omogućuje rangiranje španjolskih gradova na temelju dostupnih podataka i predlaže sveobuhvatnu strategiju upravljanja njihovim materijalnim i nematerijalnim bogatstvima. Iz rezultata se može zaključiti da gradovi pokrajine Castilla-La Mancha imaju izvrsne ljudske resurse i dobru kvalitetu života, ali da postoji prostor za poboljšanja u pogledu gradske infrastrukture i planiranj

Procjena intelektualnog kapitala u Europskoj uniji korištenjem modela znanja

This paper presents a model aimed at measuring intellectual capital as the potential knowledge of a country and apply it to the European Union. The method consists of activating accountable expenses, assumed to generate knowledge. In order to do so, efficiency indicators are used, derived from a summary of variables of structural, human and technological capitals by means of factor analysis. The results of this study for the EU25 in 2006 explain why Northern Europe has greater intellectual capital potential. They are more productive, as they manage and apply new technologies better. In human capital, Eastern countries have strong potential. The paper concludes that, at the conceptual level, this information should be used to design convergence policies and balanced development strategies to ensure economic growth.U ovom radu se predstavlja model usmjeren na mjerenje intelektualnog kapitala kao potencijalnog znanja zemlje i primjenjuje se na Europsku uniju. Metoda se sastoji u aktiviranju troškova koji doprinose generiranju znanja. Kako bi se to učinilo, koristimo pokazatelje učinkovitosti izvedene iz sažetka varijabli strukturalnih, ljudskih i tehnoloških kapitala pomoću faktorske analize. Rezultati ove studije za EU25 2006. godine objašnjavaju zašto sjeverna Europa ima veći potencijal intelektualnog kapitala. Oni su produktivniji jer bolje primjenjuju i upravljaju novim tehnologijama. Istočne zemlje imaju jak potencijal ljudskog kapitala. U radu se zaključuje da, na konceptualnoj razini, te informacije treba iskoristiti za dizajniranje konvergencijskih politika i uravnotežene strategije razvoja kako bi se osigurao gospodarski rast

Immediate loading and immediate restoration in 105 expanded-platform implants via the Diem System after a 16-month follow-up period

Objective: The aim of this study was to report on our experience and outcomes with Certain Prevail Implants and immediate loading via the Diem System after a 16-month follow-up period. Materials and Methods: Over a 16- month period, 105 (14 maxilla, 91 mandible) expanded-platform implants were placed in 18 patients (15 females, 3 males; 55.97 ±7.25 SD years). Resonance frecuency analysis (RFA) was measured on the day of placement and at 3, 12 and 16 months. All prostheses were screw mounted on IOL DIEM standard abutments. The follow-up time varied between 3 up to 16 months. Results: One implant (0.9%) failed during final prothetic placement (3 months). The RFA (ISQ) measurements at 16 months evalution for 4 mm- and 5 mm diameter implants were: 76.13 ± 5.0 SD and 76 ±7.7 SD respectively. The RFA data related to mandible and maxilla, the day 0 mean was 76.47 ± 4.75 SD and 70.13 ± 1.35 SD, at 3 months 70.53 ± 4.0 SD and 66.07 ±2.9 SD, at 12 months 68.23± 3.6 SD and 66.40 ±2.7 SD and 16 months 68.23± 3.6 SD and 66.60 ± 2.5 SD respectively. The crestal bone resorption was 0.6 mm at 16 months in platform switching implants.Conclusions: The cumulative implant survival rate during the follow-up period was 99.1% Immediate loading on IOL Diem abutments is a reliable and effective technique for edentulous patients in the maxilla and mandible