560 research outputs found

    Capacidad predictiva de las relaciones estadísticas entre los volúmenes de precipitación de las cuencas de la Península Ibérica y las temperaturas de la superficie de los océanos Atlántico y Pacífico del periodo 1946-1994

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    Ponencia presentada en: V Simposio Nacional de Predicción, celebrado en 2001 en Madrid.El objetivo del trabajo es buscar relaciones entre anomalías atmosféricas y anomalías de las temperaturas superficiales del agua del mar (SST) con distintas estaciones de retardo. Para ello se utiliza el Análisis de Correlación Canónica (ACC) entre las anomalías de SST del Atlántico y del Pacífico y las anomalías de los volúmenes de precipitación de cada una de las cuencas de la Península Ibérica en el periodo 1946-1994. Las correlaciones significativas son utilizadas para predecir. La medida de la bondad de las predicciones, se obtiene calculando las curvas ROC y el valor económico para los terciles seco, normal y húmedo. Los resultados obtenidos indican que, existe una capacidad predictiva, respecto a las SST del Atlántico para la misma estación, en la cuencas de la vertiente atlántica en invierno y en el Segura en primavera. Con respecto a las SST del Pacífico, se muestra capacidad predictiva para la cuenca Sur con dos estaciones de retardo a principios de la primavera y simultanea para el Levante a finales del verano

    La musicoterapia y su procesamiento. ¿Existe una relación con el lenguaje oral?

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    Music therapy is a therapeutic technique or practice currently used in different fields of health sciences and rehabilitative medicine. Speech therapy uses music therapy as a tool to rehabilitate complex cognitive processes, such as language. This technique presents different possibilities for its use, such as Rhythmic Auditory Stimulation (RAS), Musical Speech Stimulation (MUSTIM) or Auditory Perception Training (APT). The bibliographic review carried out in this work reflects the promising results published by different authors after using music therapy as a therapeutic practice, allowing a possible answer to the title of the work, why are such beneficial results produced in patients with language disorders when do they deal with music therapy? In this study and in order to answer this question, the possible anatomophysiological relationship between the cortical areas of perception and processing of language and that of music has been investigated.La musicoterapia es una técnica o práctica terapéutica, utilizada actualmente en diferentes campos de ciencias de la salud y la medicina rehabilitadora. La logopedia utiliza la musicoterapia como herramienta para rehabilitar procesos cognitivos complejos, como es el lenguaje. Esta técnica presenta diferentes posibilidades para su utilización, como por ejemplo Rhythmic Auditory Stimulation (RAS), Musical Speech Stimulation (MUSTIM) o Auditory Perception Training (APT). La revisión bibliográfica realizada en este trabajo, refleja los resultados prometedores publicados por diferentes autores tras utilizar la musicoterapia como práctica terapéutica, permitiendo dar una posible respuesta al título del trabajo, ¿por qué se producen resultados tan beneficiosos en pacientes con alteraciones del lenguaje cuando se tratan con musicoterapia?. En este estudio y con el fin de contestar a esta pregunta se ha investigado en la posible relación anatomofisiológica entre las áreas corticales de la percepción y procesamiento del lenguaje y el de la música

    Middle-to-late Holocene palaeoenvironmental reconstruction from the A294 ice-cave record (Central Pyrenees, northern Spain)

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    Perennial ice deposits in caves represent unique, but underexplored, terrestrial sequences that potentially contain outstanding palaeoclimatic records. Here, we present a pioneer palaeoenvironmental study of an ice deposit preserved in a small sag-type cave (A294) in the Central Pyrenees (northern Iberian Peninsula). The 9.25-m thick sequence, which is dated from 6100 ± 107 to 1888 ± 64 cal BP, represents the oldest known firn ice record worldwide. The stratigraphy (detrital layers, unconformities, and cross stratification), plant macrofossils, and isotopic signature (similarity between the ice linear distribution, δ2H = 7.83δ18O + 8.4, and the Global Meteoric Water Line) of the ice point to the diagenesis of snow introduced to the cave by winter snowstorms. Four phases of rapid ice accumulation (6100–5515, 4945–4250, 3810–3155, and 2450–1890 cal BP) are related to wetter and colder winters. Comparison of the isotopic composition (δ18O and deuterium excess) of the ice with other paleoclimate records show that both source effects and the North Atlantic Oscillation (NAO) mechanism exert a dominant influence on the ice cave record. The NAO signal may be a combination of source effects and rainfall amount. Three intervals with low ice accumulation occurred between the phases of rapid accumulation and were related to drier, and possibly warmer, winters. These centennial-scale episodes appear to be in-phase with regional arid events, as established from high altitude lacustrine records and can be correlated to global Rapid Climate Change events. The current warming trend has dramatically decreased the volume of the ice deposit in cave A294This work was supported by the Spanish Government and the European Regional Development Fund (projects CGL2009-10455/BTE, CTM2013-48639-C2-1-R CGL2016-77479-R). This is a contribution by PaleoQ and Geomorfología y Cambio Global groups (Aragón Government and European Social Fund) and IUCA (University of Zaragoza

    Importante apoyo a las políticas medioambientales y prevención y protección de la salud

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    Monográfico de la revista "Ambienta" sobre la Agencia Estatal de Meteorología (AEMET

    La red radiométrica en banda ancha de la Agencia Estatal de Meteorología

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    Póster presentado en: XXX Jornadas Científicas de la AME y el IX Encuentro Hispano Luso de Meteorología celebrado en Zaragoza, del 5 al 7 de mayo de 2008

    Agricultura Urbana, un camino para enfrentar nuevos retos: Estudio de caso de la ciudad de Palencia

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    This research aims to analyse the potential of Urban Agriculture (UA) in the city of Palencia (Castilla y León) to address the problems and challenges facing the city and analyse what factors can favour its development. In doing so, the challenges established in the Strategy for Sustainable and Integral Urban Development (EDUSI) of Palencia and the possible contribution of the AU were analysed. The data of the geographic information system of agrarian data along with semi-structured surveys and visits to managers of UA initiatives in the city, the city's participatory processes and other factors that can contribute to its promotion were analysed. The results show a drastic decrease in the horticultural function in Palencia. The contribution of the UA to face the challenges of the city of Palencia can be based on: the AU is an innovative solution with the capacity to contribute to mitigating the effects of climate change; allows a healthy leisure offer to an aging population; it can contribute to creating a culture favourable to organic, local and local food; allows innovative forms of social action, favouring the integration of different groups (retired, disabled, young people, people at risk of social exclusion...) and contributes to promoting the low-carbon city model, helping to create more resilient cities in adapting to climate change. The UA currently has, therefore, multiple functions. Participatory processes around the challenges of the city and the food system can be a good starting point for its development. Also, managers in charge are needed, a detailed analysis of the possible reusable land, transfer of agricultural land and greater support and regulation of the activity that allows the development of urban models of agriculture with a multitude of functions: social, occupational, leisure, participatory, productive (favouring close access to healthy food), providing safe outdoor spaces and fulfilling a function of natural self-regulation of ecosystems.La presente investigación tiene por objeto analizar el potencial de la agricultura urbana para afrontar los nuevos problemas y retos que se plantean las ciudades, en un estudio de caso de la ciudad de Palencia en Castilla y León. Para ello, se han analizado los retos establecidos en la Estrategia de Desarrollo Urbano Sostenible e Integral (EDUSI) de la ciudad y la posible contribución de la agricultura urbana a los mismos. Se ha calculado, con los datos del sistema de información geográfica agrarios, el potencial de agricultura urbana procedente de la recuperación de terrenos hortícolas abandonados. Mediante encuestas semiestructuradas y visitas a los gestores de las iniciativas de agricultura urbana se ha analizado la posible contribución de la agricultura urbana a los nuevos retos a los que se enfrenta la ciudad.  Los resultados muestran una drástica disminución del terreno hortícola en la ciudad de Palencia, ofreciendo un potencial de recuperación con grandes oportunidades multifuncionales. Sin embargo, las experiencias de agricultura urbana muestran que se necesitan gestores a cargo, así como un análisis pormenorizado del posible suelo agrario utilizable, y resolver la concesión de dicho suelo agrario, junto con un mayor apoyo y regulación de la actividad que permita desarrollar modelos urbanos de agricultura con  su multitud de funciones: social, ocupacional, de ocio, participativa,  productiva, proporcionar espacios seguros al aire libre y cumplir una función de autorregulación natural de los ecosistemas

    Thermographic studies of cocurrent and mixed flow spray drying of heat sensitive bioactive compounds

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    Production of powders of heat sensitive bioactive compounds in a bench scale spray drier was studied under cocurrent and mixed flow pattern conditions using two inlet air temperatures of 200 and 120 °C. Two natural colorants (riboflavin-5-phosphate and red beet) and an enzyme (alpha-amylase), were selected for experimentation. Thermographic studies showed interesting asymmetric profiles of temperatures outside and inside of the drying chamber, because turbulent air flow conditions and thermal trajectories of atomized drops during its drying process were dependent on flow patterns. Powders of natural colorants maintained its color strength, and alpha-amylase powders retain more than 82.9% of its enzyme activity even at the highest air temperature of 200 °C and using mixed flow. This work concludes that spray drying under cocurrent and mixed-flow patterns of heat labile bioactive compounds is feasible, influencing drying yields and the properties of powders obtained

    Snail1 induces IL-17 expression to inhibit adipogenesis

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    44 p.-7 fig.-1 tab. Peláez-García, Alberto et al.Adipogenesis requires a differentiation program driven by multiple transcription factors, where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits adipocyte differentiation in 3T3-L1 and murine mesenchymal stem cells (mMSC). An in-depth quantitative SILAC analysis of the nuclear fraction of Snail-induced alterations of 3T3-L1 cells was carried out. In total, 2251 overlapping proteins were simultaneously quantified in forward and reverse experiments. We observed 574 proteins deregulated by Snail1 using a fold-change ≥1.5, with 111 up- and 463 down-regulated proteins, respectively. Among other proteins, multiple transcription factors such as Trip4, OsmR, Nr2f6, Cbx6, and Prrx1 were down-regulated. Results were validated in 3T3-L1 cells and mMSC cells by Western blot and quantitative PCR. Knock-down experiments in 3T3-L1 cells demonstrated that only Nr2f6 (and Trip4 at minor extent) was required for adipocyte differentiation. Ectopic expression of Nr2f6 reversed the effects of Snail1 and promoted adipogenesis. Because Nr2f6 inhibits the expression of IL-17, we tested the effect of Snail on IL-17 expression. IL-17 and TNFα were among the most up-regulated pro-inflammatory cytokines in Snail-transfected 3T3-L1 and mMSC cells. Furthermore, the blocking of IL-17 activity in Snail-transfected cells promoted adipocyte differentiation, reverting Snail inhibition. In summary, Snail inhibits adipogenesis through a down-regulation of Nr2f6, which in turn facilitates the expression of IL-17, an anti-adipogenic cytokine. These results would support a novel and important role for Snail and Nr2f6 in obesity control.This research was supported by a grant to established research groups (AECC), grant BIO2012-31023 from the Ministry of Economy and Competitiveness, grant S2011/BMD-2344/ (Colomics2) from Comunidad de Madrid and ProteoRed-ISCIII support. Work at AGH’s lab was supported by a grant from the Ministry of Economy and Competitiveness (SAF2010-16089)Peer reviewe
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