Towards automatic hole detection of a net for fish farms by means of robotic intelligence

In the last decades fish farms became one of the most important sources of seafood. This industry is facing complex and costly problems like net holes, especially due to unexpected situations, such as depredators and storm effects. This is a complex problem because fishes can escape from the fish farms containers or a depredator can enter in the container. To solve this problem divers are needed, but this solution is difficult and sometimes can be dangerous for the diver. The main objective of this work is to present the current state of a system where an underwater robot can detect holes in the net of a fish farm. Once the robot detects the hole it will proceed to manipulate it. This task is bordered using convolutional neural networks and the BlueROV2 platform with the Newton Gripper from BlueRobotics, which will be upgraded in a second stage to perform preliminary net repairs. This work contributes in the area of aquaculture, computer vision, underwater inspection and manipulation.Peer Reviewe

MIR master underwater robotics competition: educational experience

[Resumen] En este artículo se describe la nueva competición de robótica submarina del Máster Europeo “Erasmus Mundus MIR” (Marine & Maritime Intelligent Robotics), la cual se ha iniciado en el año 2023 en dos fases. La primera fase incluye pruebas de los algoritmos en simulación, utilizando una aproximación a gemelo digital del robot BlueROV, permitiendo adquirir las imágenes del vehículo, así como mover los motores del mismo, a través del protocolo ROS (Robot Operating System). La segunda fase consiste en la adaptación y validación de los algoritmos anteriores al escenario con robots reales en el CIRTESU (Centro de Investigación en Robótica y Tecnología Subacuática) de la Universidad Jaume I de Castellón. Los estudiantes han empezado a programar el simulador durante el primer semestre, en la Universidad de Toulon, recibiendo la asistencia necesaria para el uso y programación del gemelo digital a través de ROS. Las pruebas incluyen la navegación autónoma del robot a una estación base, la navegación, y la búsqueda de objetos específicos en el fondo de un tanque de agua a través de visión por computador.[Abstract] This article describes the new underwater robotics competition of the Erasmus Mundus European Master MIR (Marine & Maritime Intelligent Robotics), which began in 2023 in two phases. The first phase includes tests of the algorithms in simulation, using a digital twin approach of the Bluerov robot, making it possible to acquire images of the vehicle, as well as move its engines, through the ROS (Robot Operating System) protocol. The second phase consists of the adaptation and validation of the algorithms prior to the scenario with real robots at the CIRTESU (Centre for Research in Robotics and Underwater Technologies) of the Jaume-I University (UJI) of Castellón. The students have started to program the simulator during the first semester, at the University of Toulon (UTLN), receiving the necessary assistance for the use and programming of the digital twin through ROS. The tests include autonomous navigation of the robot to a base station, navigation, and the search for specific objects at the bottom of a water tank through computer vision.Ministerio de Ciencia e Innovación; PDC2021-120791-C2

Towards precision medicine: defining and characterizing adipose tissue dysfunction to identify early immunometabolic risk in symptom-free adults from the GEMM family study

Interactions between macrophages and adipocytes are early molecular factors influencing adipose tissue (AT) dysfunction, resulting in high leptin, low adiponectin circulating levels and low-grade metaflammation, leading to insulin resistance (IR) with increased cardiovascular risk. We report the characterization of AT dysfunction through measurements of the adiponectin/leptin ratio (ALR), the adipo-insulin resistance index (Adipo-IRi), fasting/postprandial (F/P) immunometabolic phenotyping and direct F/P differential gene expression in AT biopsies obtained from symptom-free adults from the GEMM family study. AT dysfunction was evaluated through associations of the ALR with F/P insulin-glucose axis, lipid-lipoprotein metabolism, and inflammatory markers. A relevant pattern of negative associations between decreased ALR and markers of systemic low-grade metaflammation, HOMA, and postprandial cardiovascular risk hyperinsulinemic, triglyceride and GLP-1 curves was found. We also analysed their plasma non-coding microRNAs and shotgun lipidomics profiles finding trends that may reflect a pattern of adipose tissue dysfunction in the fed and fasted state. Direct gene differential expression data showed initial patterns of AT molecular signatures of key immunometabolic genes involved in AT expansion, angiogenic remodelling and immune cell migration. These data reinforce the central, early role of AT dysfunction at the molecular and systemic level in the pathogenesis of IR and immunometabolic disorders

Deep Multi-OMICs and Multi-Tissue Characterization in a Pre- and Postprandial State in Human Volunteers: The GEMM Family Study Research Design

Cardiovascular disease (CVD) and type 2 diabetes (T2D) are increasing worldwide. This is mainly due to an unhealthy nutrition, implying that variation in CVD risk may be due to variation in the capacity to manage a nutritional load. We examined the genomic basis of postprandial metabolism. Our main purpose was to introduce the GEMM Family Study (Genetics of Metabolic Diseases in Mexico) as a multi-center study carrying out an ongoing recruitment of healthy urban adults. Each participant received a mixed meal challenge and provided a 5-hours’ time course series of blood, buffy coat specimens for DNA isolation, and adipose tissue (ADT)/skeletal muscle (SKM) biopsies at fasting and 3 h after the meal. A comprehensive profiling, including metabolomic signatures in blood and transcriptomic and proteomic profiling in SKM and ADT, was performed to describe tendencies for variation in postprandial response. Our data generation methods showed preliminary trends indicating that by characterizing the dynamic properties of biomarkers with metabolic activity and analyzing multi-OMICS data it could be possible, with this methodology and research design, to identify early trends for molecular biology systems and genes involved in the fasted and fed states

Replication of Integrative Data Analysis for Adipose Tissue Dysfunction, Low-Grade Inflammation, Postprandial Responses and OMICs Signatures in Symptom-Free Adults

We previously reported preliminary characterization of adipose tissue (AT) dysfunction through the adiponectin/leptin ratio (ALR) and fasting/postprandial (F/P) gene expression in subcutaneous (SQ) adipose tissue (AT) biopsies obtained from participants in the GEMM study, a precision medicine research project. Here we present integrative data replication of previous findings from an increased number of GEMM symptom-free (SF) adults (N = 124) to improve characterization of early biomarkers for cardiovascular (CV)/immunometabolic risk in SF adults with AT dysfunction. We achieved this goal by taking advantage of the rich set of GEMM F/P 5 h time course data and three tissue samples collected at the same time and frequency on each adult participant (F/P blood, biopsies of SQAT and skeletal muscle (SKM)). We classified them with the presence/absence of AT dysfunction: low (1) ALR. We also examined the presence of metabolically healthy (MH)/unhealthy (MUH) individuals through low-grade chronic subclinical inflammation (high sensitivity C-reactive protein (hsCRP)), whole body insulin sensitivity (Matsuda Index) and Metabolic Syndrome criteria in people with/without AT dysfunction. Molecular data directly measured from three tissues in a subset of participants allowed fine-scale multi-OMIC profiling of individual postprandial responses (RNA-seq in SKM and SQAT, miRNA from plasma exosomes and shotgun lipidomics in blood). Dynamic postprandial immunometabolic molecular endophenotypes were obtained to move towards a personalized, patient-defined medicine. This study offers an example of integrative translational research, which applies bench-to-bedside research to clinical medicine. Our F/P study design has the potential to characterize CV/immunometabolic early risk detection in support of precision medicine and discovery in SF individuals

Plum pox virus

International audienceA few natural sources of resistance to PPV have been found so far in Prunus species, which are being used in classical breeding programs. Different genetic engineering approaches are being used to generate resistance to PPV while a transgenic plum, "HoneySweet", transformed with the viral CP gene has demonstrated high resistance to PPV in field tests in several countries and has obtained regulatory approval in the USA

Jornadas Nacionales de Robótica y Bioingeniería 2023: Libro de actas

Las Jornadas de Robótica y Bioingeniería de 2023 tienen lugar en la Escuela Técnica Superior de Ingeniería Industrial de la Universidad Politécnica de IVIadrid, entre los días 14 y 16 de junio de 2023. En este evento propiciado por el Comité Español de Automática (CEA) tiene lugar la celebración conjunta de las XII Jornadas Nacionales de Robótica y el XIV Simposio CEA de Bioingeniería. Las Jornadas Nacionales de Robótica es un evento promovido por el Grupo Temático de Robótica (GTRob) de CEA para dar visibilidad y mostrar las actividades desarrolladas en el ámbito de la investigación y transferencia tecnológica en robótica. Asimismo, el propósito de Simposio de Bioingeniería, que cumple ahora su decimocuarta dicción, es el de proporcionar un espacio de encuentro entre investigadores, desabolladores, personal clínico, alumnos, industriales, profesionales en general e incluso usuarios que realicen su actividad en el ámbito de la bioingeniería. Estos eventos se han celebrado de forma conjunta en la anualidad 2023. Esto ha permitido aunar y congregar un elevado número de participantes tanto de la temática robótica como de bioingeniería (investigadores, profesores, desabolladores y profesionales en general), que ha posibilitado establecer puntos de encuentro, sinergias y colaboraciones entre ambos. El programa de las jornadas aúna comunicaciones científicas de los últimos resultados de investigación obtenidos, por los grupos a nivel español más representativos dentro de la temática de robótica y bioingeniería, así como mesas redondas y conferencias en las que se debatirán los temas de mayor interés en la actualidad. En relación con las comunicaciones científicas presentadas al evento, se ha recibido un total de 46 ponencias, lo que sin duda alguna refleja el alto interés de la comunidad científica en las Jornadas de Robótica y Bioingeniería. Estos trabajos serán expuestos y presentados a lo largo de un total de 10 sesiones, distribuidas durante los diferentes días de las Jornadas. Las temáticas de los trabajos cubren los principales retos científicos relacionados con la robótica y la bioingeniería: robótica aérea, submarina, terrestre, percepción del entorno, manipulación, robótica social, robótica médica, teleoperación, procesamiento de señales biológicos, neurorehabilitación etc. Confiamos, y estamos seguros de ello, que el desarrollo de las jornadas sea completamente productivo no solo para los participantes en las Jornadas que podrán establecer nuevos lazos y relaciones fructíferas entre los diferentes grupos, sino también aquellos investigadores que no hayan podido asistir. Este documento que integra y recoge todas las comunicaciones científicas permitirá un análisis más detallado de cada una de las mismas