The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

Antibióticos naturales: Mito o realidad Natural antibiotics: Myth or reality

Resumen Desde su descubrimiento, el uso indiscriminado de los antibióticos en la práctica médica ha provocado, entre otros males, el desarrollo de cepas bacterianas resistentes. Con el objetivo de brindar un material ameno y actualizado, se realizó una revisión bibliográfica profundizando en los antecedentes históricos del tema y las nuevas tendencias vigentes a nivel mundial para el tratamiento de los casos. Se concluyó que es necesario crear conciencia sobre las consecuencias que se derivan del uso irracional de los antibióticos, ya bien sea por el personal médico como en la comunidad; y que deben aplicarse acciones médicas específicas encaminadas a la promoción de estilos de vida saludables y a la prevención de las enfermedades, utilizando medios naturales o tradicionales de curación aplicados en perfecta armonía con nuestra medicina tecnológica actual.<br>Since its discovery, the indiscriminate use of antibiotics in medical practice has caused, among other ailments, the development of resistant bacterial strains. Aimed at providing an updated material, it was made a bibliographic review that goes deep into the historical background of the topic and into the new standing trends at the world level to treat the cases. It was concluded that it is necessary that people be aware of the consequences derived from the irrational use of antibiotics on the part of the medical personnel or of the community, and that specific medical actions directed to the promotion of healthy lifestyles and to the prevention of diseases should be applied by using natural or traditional means of cure applied in perfect harmony with our present technological medicine

Intervención sobre hipertensión arterial en un consultorio médico Blood hypertension intervention in a physician´s office

Se realizó un estudio de intervención sobre HTA en un grupo de pacientes hipertensos del Consultorio No. 3, correspondiente al Policlínico "Luis Galván Soca", del municipio Centro Habana, en el que, de un total de 75 pacientes para un 13,3 %, se aplicó el estudio a 60 hipertensos, con el fin de saber el nivel de conocimiento que tenían sobre su enfermedad de base, en cuanto a conceptos, definiciones y complicaciones, entre otros aspectos. Después de realizada la investigación, se obtuvo como resultado de las encuestas aplicadas, en primera instancia, que los pacientes conocían muy poco sobre su enfermedad de base, y que después de impartido el curso, que contó de 4 intervenciones, se observó un aumento del conocimiento de la enfermedad que padecen en sentido general, por lo cual vemos cumplido el objetivo trazado en esta investigación.<br>An intervention study on hypertension was carried out in a group of hypertensive patients from the physician´s office no.3 from "Luis Galván Soca" polyclinics in Centro Havana municipality. Of 75 in all, the study was applied to 60 hypertensives to find out their level of knowledge about their underlying disease in terms of concepts, definitions and complications, among other things. After the research, the result of the applied surveys yielded that the patients knew veryllittle about their underlying disease and that, after the training comprising 4 interventions, increased knowledge about their disease in general was observed, so we believe that the objective of this research study has been achieved

Investigación educativa en las aulas de primaria

Reúne trabajos derivados de la experiencias de diversos docentes en educación primaria en los siguientes temas: Tecnología de Información y Comunicación, educación inclusiva, enseñanza de la música, educación física, enseñanza de la historia, acoso escolar, auto-evaluación, métodos de enseñanza, inteligencia emocional, percepción del alumno, marco cognitivo en comprensión lectora y comunicación escuela-familia