Internal Motility in Stiffening Actin-Myosin Networks

We present a study on filamentous actin solutions containing heavy meromyosin subfragments of myosin II motor molecules. We focus on the viscoelastic phase behavior and internal dynamics of such networks during ATP depletion. Upon simultaneously using micro-rheology and fluorescence microscopy as complementary experimental tools, we find a sol-gel transition accompanied by a sudden onset of directed filament motion. We interpret the sol-gel transition in terms of myosin II enzymology, and suggest a "zipping" mechanism to explain the filament motion in the vicinity of the sol-gel transition.Comment: 4 pages, 3 figure

Onset of collective and cohesive motion

We study the onset of collective motion, with and without cohesion, of groups of noisy self-propelled particles interacting locally. We find that this phase transition, in two space dimensions, is always discontinuous, including for the minimal model of Vicsek et al. [Phys. Rev. Lett. {\bf 75},1226 (1995)] for which a non-trivial critical point was previously advocated. We also show that cohesion is always lost near onset, as a result of the interplay of density, velocity, and shape fluctuations.Comment: accepted for publication in Phys. Rev. Let

CEDIM Risk Explorer ? a map server solution in the project "Risk Map Germany"

International audienceThe project "Risk Map Germany" at the Center for Disaster Management and Risk Reduction Technology (CEDIM) aims at visualizing hazards, vulnerabilities and risks associated with natural and man made hazards. CEDIM as an interdisciplinary project unified various expertise like earthquake, storm and flood disaster research. Our aim was to visualize the manifold data exploration in thematic maps. The implemented Web-GIS solution "CEDIM Risk Explorer" represents the map visualizations of the different risk research. This Web-GIS integrates results from interdisciplinary work as maps of hazard, vulnerability and risk in one application and offers therefore new cognitions to the user by enabling visual comparisons. The present paper starts with a project introduction and a literature review of distributed GIS environments. Further the methods of map realization and visualization in the selected technical solution is worked out. Finally, the conclusions give the perspectives for future developments to the "CEDIM Risk Explorer"

The North Ecliptic Pole Wide survey of AKARI: a near- and mid-infrared source catalog

We present a photometric catalog of infrared (IR) sources based on the North Ecliptic PoleWide field (NEP-Wide) survey of AKARI, which is an infrared space telescope launched by Japan. The NEP-Wide survey covered 5.4 deg2 area, a nearly circular shape centered on the North Ecliptic Pole, using nine photometric filter-bands from 2 - 25 {\mu}m of the Infrared Camera (IRC). Extensive efforts were made to reduce possible false objects due to cosmic ray hits, multiplexer bleeding phenomena around bright sources, and other artifacts. The number of detected sources varied depending on the filter band: with about 109,000 sources being cataloged in the near-IR bands at 2 - 5 {\mu}m, about 20,000 sources in the shorter parts of the mid-IR bands between 7 - 11 {\mu}m, and about 16,000 sources in the longer parts of the mid-IR bands, with \sim 4,000 sources at 24 {\mu}m. The estimated 5? detection limits are approximately 21 magnitude (mag) in the 2 - 5 {\mu}m bands, 19.5 - 19 mag in the 7 - 11 {\mu}m, and 18.8 - 18.5 mag in the 15 - 24 {\mu}m bands in the AB magnitude scale. The completenesses for those bands were evaluated as a function of magnitude: the 50% completeness limits are about 19.8 mag at 3 {\mu}m, 18.6 mag at 9 {\mu}m, and 18 mag at 18 {\mu}m band, respectively. To construct a reliable source catalog, all of the detected sources were examined by matching them with those in other wavelength data, including optical and ground-based near-IR bands. The final band-merged catalog contains about 114,800 sources detected in the IRC filter bands. The properties of the sources are presented in terms of the distributions in various color-color diagrams.Comment: Accepted for publication in A&A, 23 pages, 27 figure

The effect of irregular breathing patterns on internal target volumes in four-dimensional CT and cone-beam CT images in the context of stereotactic lung radiotherapy

Purpose: Stereotactic lung radiotherapy is complicated by tumor motion from patient respiration. Four-dimensional CT (4DCT) imaging is a motion compensation method used in treatment planning to generate a maximum intensity projection (MIP) internal target volume (ITV). Image guided radiotherapy during treatment may involve acquiring a volumetric cone-beam CT (CBCT) image and visually aligning the tumor to the planning 4DCT MIP ITV contour. Moving targets imaged with CBCT can appear blurred and currently there are no studies reporting on the effect that irregular breathing patterns have on CBCT volumes and their alignment to 4DCT MIP ITV contours. The objective of this work was therefore to image a phantom moving with irregular breathing patterns to determine whether any configurations resulted in errors in volume contouring or alignment. Methods: A Perspex thorax phantom was used to simulate a patient. Three wooden "lung" inserts with embedded Perspex "lesions" were moved up to 4 cm with computer-generated motion patterns, and up to 1 cm with patient-specific breathing patterns. The phantom was imaged on 4DCT and CBCT with the same acquisition settings used for stereotactic lung patients in the clinic and the volumes on all phantom images were contoured. This project assessed the volumes for qualitative and quantitative changes including volume, length of the volume, and errors in alignment between CBCT volumes and 4DCT MIP ITV contours

Characteristic QSO Accretion Disk Temperatures from Spectroscopic Continuum Variability

Using Sloan Digital Sky Survey (SDSS) quasar spectra taken at multiple epochs, we find that the composite flux density differences in the rest frame wavelength range 1300-6000 AA can be fit by a standard thermal accretion disk model where the accretion rate has changed from one epoch to the next (without considering additional continuum emission components). The fit to the composite residual has two free parameters: a normalizing constant and the average characteristic temperature $\bar{T}^*$. In turn the characteristic temperature is dependent on the ratio of the mass accretion rate to the square of the black hole mass. We therefore conclude that most of the UV/optical variability may be due to processes involving the disk, and thus that a significant fraction of the UV/optical spectrum may come directly from the disk.Comment: 31 pages, 8 figure

Evaluation of MOSFETs for entrance dose dosimetry for 6 and 10 MV photons with a custom made build up cap

Copyright © 2007 ACPSEM. All rights reserved. The dcoument attached has been archived with permission from the publisher.Commercially available MOSFETs, Thomson and Nielsen TN502-RD, were evaluated for suitability as an entrance dose in vivo dosimeter for 6MV and 10MV. Detector response was normally distributed around a mean (skewness=-0.01±0.24, kurtosis=-0.09±0.48) with a mean of 110.6 mV/Gy, with a standard deviation of 2.4% at 0.86 Gy. The standard deviation of readings increased with decreasing dose and increased at a rate greater than inverse square. The linearity coefficient was 0.9999. No significant dependence on angle, field size, dose rate, energy or time was observed. As such, they would be useful for entrance dose in vivo dosimetry. With a custom made build up cap corrections were required for field size, wedge, beam energy and tray factors, showing that build up cap design is an important consideration for entrance dose in vivo dosimetry using MOSFETs.J. P. Morton, M. Bhat, A. Kovendy and T. Williamshttp://www.acpsem.org.au/journal/abstract/abstract_3002.html#abs0

Library Cultures of Data Curation: Adventures in Astronomy

University libraries are partnering with disciplinary data producers to provide long-term digital curation of research datasets. Managing dataset producer expectations and guiding future development of library services requires understanding the decisions libraries make about curatorial activities, why they make these decisions, and the effects on future data reuse. We present a study, comprising interviews (n=43) and ethnographic observation, of two university libraries who partnered with the Sloan Digital Sky Survey (SDSS) collaboration to curate a significant astronomy dataset. The two libraries made different choices of the materials to curate and associated services, which resulted in different reuse possibilities. Each of the libraries offered partial solutions to the SDSS leaders’ objectives. The libraries’ approaches to curation diverged due to contextual factors, notably the extant infrastructure at their disposal (including technical infrastructure, staff expertise, values and internal culture, and organizational structure). The Data Transfer Process case offers lessons in understanding how libraries choose curation paths and how these choices influence possibilities for data reuse. Outcomes may not match data producers’ initial expectations but may create opportunities for reusing data in unexpected and beneficial ways