Acoustic and linguistic features influence talker changedetection

A listening test is proposed in which human participants detect talker changes in two natural, multi-talker speech stimuli sets—a familiar language (English) and an unfamiliar language (Chinese). Miss rate, false-alarm rate, and response times (RT) showed a significant dependence on language familiarity. Linear regression modeling of RTs using diverse acoustic features derived from the stimuli showed recruitment of a pool of acoustic features for the talker change detection task. Further, benchmarking the same task against the state-of-the-art machine diarization system showed that the machine system achieves human parity for the familiar language but not for the unfamiliar language

A Pulsational Model for the Orthogonal Polarization Modes in Radio Pulsars

In an earlier paper, we introduced a model for pulsars in which non-radial oscillations of high spherical degree (\el) aligned to the magnetic axis of a spinning neutron star were able to reproduce subpulses like those observed in single-pulse measurements of pulsar intensity. The model did not address polarization, which is an integral part of pulsar emission. Observations show that many pulsars emit radio waves that appear to be the superposition of two linearly polarized emission modes with orthogonal polarization angles. In this paper, we extend our model to incorporate linear polarization. As before, we propose that pulsational displacements of stellar material modulate the pulsar emission, but now we apply this modulation to a linearly-polarized mode of emission, as might be produced by curvature radiation. We further introduce a second polarization mode, orthogonal to the first, that is modulated by pulsational velocities. We combine these modes in superposition to model the observed Stokes parameters in radio pulsars.Comment: 19 pages, 4 figures accepted Ap

The Optical Polarisation of the Vela Pulsar revisited

In this work we present a revised measurement of the phase-averaged optical polarisation of the Vela pulsar (PSR B0833-45), for which only one value has been published so far (Wagner & Seifert 2000). Our measurement has been obtained through an accurate reanalysis of archival polarisation observations obtained with the FORS instrument at the VLT. We have measured a phase-averaged linear polarisation degree P=9.4% +/- 4% and a position angle 146 +/- 11 deg, very close to the ones of the axis of symmetry of the X-ray arcs and jets detected by Chandra and of the pulsar proper motion.We have compared the measured phase-averaged optical polarisation with the expectations of different pulsars' magnetosphere models. We have found that all models consistently predict too large values of the phase-averaged linear polarization with respect to the observed one. This is probably a consequence of present models' limitations which neglect the contributions of various depolarisation effects. Interestingly, for the outer gap model we have found that, assuming synchrotron radiation for the optical emission, the observed polarisation position angle also implies an alignment between the pulsar rotational axis and the axis of symmetry of the X-ray arcs and jets.Comment: 8 pages, 4 figure

The Origin of Blue-Green Window and the Propagation of Radiation in Ocean Waters

A review of the present knowledge about the origin of blue-green window in the attenuation spectrum of ocean waters is presented. The various physical mechanisms which contribute to the formation of the w-indow are dealt separately and discussed. The typical values of attenuation coefficient arising out of the various processes are compiled to obtain the total beam attenuation coefficient. These values are then compared with measured values of attenuation coefficient for ocean waters collected from Arabian sea and Bay of Bengal. The region of minimum attenuation in pure particle-free sea water is found to be at 450 to 500 nm. It is sbown that in the presence of suspended 'particlesand chlorophyll, the window shifts to longer wavelength side. Some suggestions for future work in this area are also given in the concluding section

Enhancing hole mobility in III-V semiconductors

Transistors based on III-V semiconductor materials have been used for a variety of analog and high frequency applications driven by the high electron mobilities in III-V materials. On the other hand, the hole mobility in III-V materials has always lagged compared to group-IV semiconductors such as silicon and germanium. In this paper we explore the used of strain and heterostructure design guided by bandstructure modeling to enhance the hole mobility in III-V materials. Parameters such as strain, valence band offset, effective masses and splitting between the light and heavy hole bands that are important for optimizing hole transport are measured quantitatively using various experimental techniques. A peak Hall mobility for the holes of 960cm2/Vs is demonstrated and the high hole mobility is maintained even at high sheet charge.Comment: 18 pages, 21 figure

Observations of Non-radial Pulsations in Radio Pulsars

We introduce a model for pulsars in which non-radial oscillations of high spherical degree (l) aligned to the magnetic axis of a spinning neutron star reproduce the morphological features of pulsar beams. In our model, rotation of the pulsar carries a pattern of pulsation nodes underneath our sightline, reproducing the longitude stationary structure seen in average pulse profiles, while the associated time-like oscillations reproduce "drifting subpulses"--features that change their longitude between successive pulsar spins. We will show that the presence of nodal lines can account for observed 180 degree phase jumps in drifting subpulses and their otherwise poor phase stability, even if the time-like oscillations are strictly periodic. Our model can also account for the "mode changes" and "nulls" observed in some pulsars as quasiperiodic changes between pulsation modes of different l or radial overtone n, analogous to pulsation mode changes observed in oscillating white dwarf stars. We will discuss other definitive and testable requirements of our model and show that they are qualitatively supported by existing data. While reserving judgment until the completion of quantitative tests, we are inspired enough by the existing observational support for our model to speculate about the excitation mechanism of the non-radial pulsations, the physics we can learn from them, and their relationship to the period evolution of pulsars.Comment: 28 pages, 9 figures (as separate png files), Astrophysical Journal, in pres

Synthesis and structural characterization of cyclic aryl ethers

Publisher's version/PDFThe facile preparation of macrocyclic ethers is achieved using S[subscript N]Ar reactions of (dichlorobenzene)CpFe[superscript +) complexes with various dinucleophiles, followed by photolytic demetallation; X-ray crystallography gives unequivocal structural proof for one of these macrocycles

Formation of the Radio Profile Components of the Crab Pulsar

The induced Compton scattering of radio emission off the particles of the ultrarelativistic electron-positron plasma in the open field line tube of a pulsar is considered. We examine the scattering of a bright narrow radio beam into the background over a wide solid angle and specifically study the scattering in the transverse regime, which holds in a moderately strong magnetic field. Making use of the angular distribution of the scattered intensity and taking into account the effect of rotational aberration in the scattering region, we simulate the profiles of the backscattered components as applied to the Crab pulsar. It is suggested that the interpulse (IP), the high-frequency interpulse (IP') and the pair of the so-called high-frequency components (HFC1 and HFC2) result from the backward scattering of the main pulse (MP), precursor (PR) and the low-frequency component (LFC), respectively. The components of the high-frequency profiles, the IP' and HFCs, are interpreted for the first time. The HFC1 and HFC2 are argued to be a single component split by the rotational aberration close to the light cylinder. It is demonstrated that the observed spectral and polarization properties of the profile components of the Crab pulsar as well as the giant pulse phenomenon outside of the MP can be explained in terms of our model.Comment: Accepted for publication in MNRA

EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity

Mycobacterium tuberculosis (Mtb) requires the ESX1 specialized protein secretion system for virulence, for triggering cytosolic immune surveillance pathways, and for priming an optimal CD8+ T cell response. This suggests that ESX1 might act primarily by destabilizing the phagosomal membrane that surrounds the bacterium. However, identifying the primary function of the ESX1 system has been difficult because deletion of any substrate inhibits the secretion of all known substrates, thereby abolishing all ESX1 activity. Here we demonstrate that the ESX1 substrate EspA forms a disulfide bonded homodimer after secretion. By disrupting EspA disulfide bond formation, we have dissociated virulence from other known ESX1-mediated activities. Inhibition of EspA disulfide bond formation does not inhibit ESX1 secretion, ESX1-dependent stimulation of the cytosolic pattern receptors in the infected macrophage or the ability of Mtb to prime an adaptive immune response to ESX1 substrates. However, blocking EspA disulfide bond formation severely attenuates the ability of Mtb to survive and cause disease in mice. Strikingly, we show that inhibition of EspA disulfide bond formation also significantly compromises the stability of the mycobacterial cell wall, as does deletion of the ESX1 locus or individual components of the ESX1 system. Thus, we demonstrate that EspA is a major determinant of ESX1-mediated virulence independent of its function in ESX1 secretion. We propose that ESX1 and EspA play central roles in the virulence of Mtb in vivo because they alter the integrity of the mycobacterial cell wall