23 research outputs found
Current concepts of myelodysplastic syndrome: literature review
Myelodysplastic syndrome (MDS) is a heterogeneous group of
clonal diseases of the blood system arising from mutation of the hematopoietic stem
cell and characterized by cytopenia as a result of ineffective hematopoiesis, signs of
dysmyelopoiesis and a high risk of transformation into acute leukemia. More than
80% of patients with MDS are over 60 years old. About 25 thousand new cases are
diagnosed annually in Europe. Given the steady aging of the European population, it
is believed that the number of patients with MDS will only increase in the coming
decades. In addition, signs of myelodysplasia can be detected in the bone marrow or
peripheral blood, not only in MDS, but also in other non-clonal diseases. The role of
thyroid hormones in hematopoiesis is known, which does not exclude the
development of dysmyelopoiesis in hypothyroidism
Myelodysplastic syndrome on the background of severe hypothyroidism: case report
Myelodysplastic syndrome (MDS) is a heterogeneous group of
clonal diseases of the blood system arising from mutation of the hematopoietic stem
cell and characterized by cytopenia as a result of ineffective hematopoiesis, signs of
dysmyelopoiesis and a high risk of transformation into acute leukemia. More than
80% of patients with MDS are over 60 years old. About 25 thousand new cases are
diagnosed annually in Europe. Given the steady aging of the European population, it
is believed that the number of patients with MDS will only increase in the coming
decades. In addition, signs of myelodysplasia can be detected in the bone marrow or
peripheral blood, not only in MDS, but also in other non-clonal diseases. The role of
thyroid hormones in hematopoiesis is known, which does not exclude the
development of dysmyelopoiesis in hypothyroidism. The article presents the
classification, clinical manifestations of primary MDS and a clinical case of the development of the disease against the background of severe hypothyroidism with
features of the course of MDS
The effect of nanosecond ultrawideband electromagnetic radiation on xenogeneic erythrocytes
Experiments were the intention to investigate the effect of short-pulse ultrawideband electromagnetic radiation on biological objects. An insulated rod antenna excited by a high-current electron beam (E ~ 0.5 to 1.0 MeV, I ~ 4 to 10 kA, τ ≈ 15 ns) served as a radiation source. The objects to be irradiated, i.e., erythrocytes of both donors and diabetics, were put in the regions with field intensity varying from 100 to 1000 V/cm. The effect of radiation on the lifetime and shape of erythrocytes on the permeability of erythrocyte membranes for the penetrating nonelectrolyte (1 M glycerin) and the state of intracorpuscular hemoglobin was investigated by the methods of small-angle light scattering, UV spectrometry and phase-contrast microscopy
Measurement of and between 3.12 and 3.72 GeV at the KEDR detector
Using the KEDR detector at the VEPP-4M collider, we have measured
the values of and at seven points of the center-of-mass
energy between 3.12 and 3.72 GeV. The total achieved accuracy is about or
better than at most of energy points with a systematic uncertainty of
about . At the moment it is the most accurate measurement of in
this energy range
New precise determination of the \tau lepton mass at KEDR detector
The status of the experiment on the precise lepton mass measurement
running at the VEPP-4M collider with the KEDR detector is reported. The mass
value is evaluated from the cross section behaviour around the
production threshold. The preliminary result based on 6.7 pb of data is
MeV. Using 0.8 pb of data
collected at the peak the preliminary result is also obtained:
eV.Comment: 6 pages, 8 figures; The 9th International Workshop on Tau-Lepton
Physics, Tau0
Measurement of \Gamma_{ee}(J/\psi)*Br(J/\psi->e^+e^-) and \Gamma_{ee}(J/\psi)*Br(J/\psi->\mu^+\mu^-)
The products of the electron width of the J/\psi meson and the branching
fraction of its decays to the lepton pairs were measured using data from the
KEDR experiment at the VEPP-4M electron-positron collider. The results are
\Gamma_{ee}(J/\psi)*Br(J/\psi->e^+e^-)=(0.3323\pm0.0064\pm0.0048) keV,
\Gamma_{ee}(J/\psi)*Br(J/\psi->\mu^+\mu^-)=(0.3318\pm0.0052\pm0.0063) keV.
Their combinations
\Gamma_{ee}\times(\Gamma_{ee}+\Gamma_{\mu\mu})/\Gamma=(0.6641\pm0.0082\pm0.0100)
keV,
\Gamma_{ee}/\Gamma_{\mu\mu}=1.002\pm0.021\pm0.013 can be used to improve
theaccuracy of the leptonic and full widths and test leptonic universality.
Assuming e\mu universality and using the world average value of the lepton
branching fraction, we also determine the leptonic \Gamma_{ll}=5.59\pm0.12 keV
and total \Gamma=94.1\pm2.7 keV widths of the J/\psi meson.Comment: 7 pages, 6 figure
Search for narrow resonances in e+ e- annihilation between 1.85 and 3.1 GeV with the KEDR Detector
We report results of a search for narrow resonances in e+ e- annihilation at
center-of-mass energies between 1.85 and 3.1 GeV performed with the KEDR
detector at the VEPP-4M e+ e- collider. The upper limit on the leptonic width
of a narrow resonance Gamma(R -> ee) Br(R -> hadr) < 120 eV has been obtained
(at 90 % C.L.)
Measurement of main parameters of the \psi(2S) resonance
A high-precision determination of the main parameters of the \psi(2S)
resonance has been performed with the KEDR detector at the VEPP-4M e^{+}e^{-}
collider in three scans of the \psi(2S) -- \psi(3770) energy range. Fitting the
energy dependence of the multihadron cross section in the vicinity of the
\psi(2S) we obtained the mass value
M = 3686.114 +- 0.007 +- 0.011 ^{+0.002}_{-0.012} MeV and the product of the
electron partial width by the branching fraction into hadrons \Gamma_{ee}*B_{h}
= 2.233 +- 0.015 +- 0.037 +- 0.020 keV.
The third error quoted is an estimate of the model dependence of the result
due to assumptions on the interference effects in the cross section of the
single-photon e^{+}e^{-} annihilation to hadrons explicitly considered in this
work.
Implicitly, the same assumptions were employed to obtain the charmonium
leptonic width and the absolute branching fractions in many experiments.
Using the result presented and the world average values of the electron and
hadron branching fractions, one obtains the electron partial width and the
total width of the \psi(2S):
\Gamma_{ee} =2.282 +- 0.015 +- 0.038 +- 0.021 keV,
\Gamma = 296 +- 2 +- 8 +- 3 keV.
These results are consistent with and more than two times more precise than
any of the previous experiments
New precision measurement of the - and -meson masses
A new high precision measurement of the - and -meson masses
has been performed at the VEPP-4M collider using the KEDR detector. The
resonant depolarization method has been employed for the absolute calibration
of the beam energy. The following mass values have been obtained:
MeV,
MeV.
The relative measurement accuracy has reached for and
for , approximately 3 times better than in the previous
precise experiments.Comment: 12 pages, 4 tables, 10 figure
Національна доповідь про стан і перспективи розвитку освіти в Україні: монографія (До 30-річчя незалежності України)
The publication provides a comprehensive analysis of the state and development of national education over the 30 years of Ukraine’s independence, identifies current problems in education, ascertains the causes of their emergence, offers scientifically reasoned ways to modernise domestic education in the context of globalisation, European integration, innovative development, and national self-identification.
Designed for legislators, state officials, education institutions leaders, teaching and academic staff, the general public, all those who seek to increase the competitiveness of Ukrainian education in the context of civilisation changes.У виданні здійснено всебічний аналіз стану і розвитку національної освіти за 30-річний період незалежності України, визначено актуальні проблеми освітньої сфери, виявлено причини їх виникнення, запропоновано науково обґрунтовані шляхи модернізації вітчизняної освіти в умовах глобалізації, європейської інтеграції, інноваційного розвитку та національної самоідентифікації. Розраховано на законодавців, державних управлінців, керівників закладів освіти, педагогічних і науково-педагогічних працівників, широку громадськість, усіх, хто прагне підвищення конкурентоспроможності української освіти в контексті цивілізаційних змін