Haunted by Defeat: Imperial Sexualities, Prostitution and the Emergence of Postwar Japan

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A search for transit timing variation

Photometric follow-ups of transiting exoplanets (TEPs) may lead to discoveries of additional, less massive bodies in extrasolar systems. This is possible by detecting and then analysing variations in transit timing of transiting exoplanets. In 2009 we launched an international observing campaign, the aim of which is to detect and characterise signals of transit timing variation (TTV) in selected TEPs. The programme is realised by collecting data from 0.6--2.2-m telescopes spread worldwide at different longitudes. We present our observing strategy and summarise first results for WASP-3b with evidence for a 15 Earth-mass perturber in an outer 2:1 orbital resonance.Comment: Poster contribution to Detection and Dynamics of Transiting Exoplanets (Haute Provence Observatory Colloquium, 23-27 August 2010

Thermal evolution and structure models of the transiting super-Earth GJ 1214b

The planet GJ 1214b is the second known super-Earth with a measured mass and radius. Orbiting a quiet M-star, it receives considerably less mass-loss driving X-ray and UV radiation than CoRoT-7b, so that the interior may be quite dissimilar in composition, including the possibility of a large fraction of water. We model the interior of GJ 1214b assuming a two-layer (envelope+rock core) structure where the envelope material is either H/He, pure water, or a mixture of H/He and H2O. Within this framework we perform models of the thermal evolution and contraction of the planet. We discuss possible compositions that are consistent with Mp=6.55 ME, Rp=2.678 RE, an age tau=3-10 Gyr, and the irradiation level of the atmosphere. These conditions require that if water exists in the interior, it must remain in a fluid state, with important consequences for magnetic field generation. These conditions also require the atmosphere to have a deep isothermal region extending down to 80-800 bar, depending on composition. Our results bolster the suggestion of a metal-enriched H/He atmosphere for the planet, as we find water-world models that lack an H/He atmosphere to require an implausibly large water-to-rock ratio of more than 6:1. We instead favor a H/He/H2O envelope with high water mass fraction (~0.5-0.85), similar to recent models of the deep envelope of Uranus and Neptune. Even with these high water mass fractions in the H/He envelope, generally the bulk composition of the planet can have subsolar water:rock ratios. Dry, water-enriched, and pure water envelope models differ to an observationally significant level in their tidal Love numbers k2 of respectively ~0.018, 0.15, and 0.7.Comment: 11 pages, 6 figures, 1 table, accepted to Ap

Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose.

Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives. Prostaglandin analogs are a mainstay glaucoma therapy. However, conventional eyedroppers deliver 30-50 µL drops that greatly exceed the physiologic 7-µL ocular tear film capacity. Eyedropper overdosing floods the eye with excess drug compounds and preservatives, resulting in ocular surface toxicity, periorbitopathy, and other well-characterized ocular side effects. Piezoelectric high-precision microdosing provides targeted delivery that can reduce exposure to both drug and preservatives compared to conventional eyedropper delivery, with the potential to deliver similar biologic effect. Methods:Both eyes (N=60) of 30 healthy volunteers received single 8-µL microdoses of 0.005% latanoprost (0.4 µg; µRx-latanoprost) on the morning of Days 1 and 2 using a high-precision, piezo-print horizontal delivery system. Diurnal IOP was measured before and 2 days after microdosing. Main efficacy outcomes were diurnal IOP change after µRx-latanoprost microdosing and accurate microdosing success rates, and the primary safety outcome was adverse event (AE) incidence. Results:µRx-latanoprost reduced baseline IOP by 26% and 30% at 1 and 2 days postadministration, respectively. Successful topical dosing was achieved in 100% of technician-assisted deliveries. All patients successfully self-administered microdoses after receiving training. Microdose administration was well tolerated and did not result in any AEs. Conclusion:Microdosing of 0.4 µg of µRx-latanoprost achieved significant IOP reduction. Lower ocular exposure with topical prostaglandin analog microdosing can enable new therapeutic opportunities for optimizing glaucoma treatment. Microdosing may also be beneficial in reducing ocular side effects associated with excessive drug product and preservatives often used to treat chronic ocular diseases such as glaucoma

The Effects Of An Intervention Program On Psychosocial Factors And Consequences During The COVID‐19 Pandemic In A Chilean Technology Services Company: A Quasiexperimental Study

Background and Aims: During the COVID‐19 pandemic, mental health became a relevant factor in people's performance within organizations. The aim of this study was to analyze the effects of an organizational intervention program on the psychosocial factors of demands, resources, and the consequences of psychosocial risks in a technology services company during the COVID‐19 pandemic. Methods: A quasiexperimental study was carried out with 105 employees who took part in an 8‐week intervention program divided into two large stages. Pre‐ and postmeasurements were collected using the UNIPSICO Questionnaire, considering its factors of demands, resources, and consequences of psychosocial risks. The Spanish Burnout Inventory (SBI) was also included. Results: The results showed significant improvements in the perception of the following psychosocial demand factors: Role conflict (p < 0.001), Role ambiguity, workload, interpersonal conflicts (p < 0.05). In the resource factors: autonomy, work social support, feedback (p < 0.001) Resources at work, transformational leadership, and self‐efficacy (p < 0.05). In addition, all the consequences of psychosocial risks have improvements: Indolence, emotional exhaustion, and job satisfaction (p < 0.001), Burnout syndrome, enthusiasm toward the job, and psychosomatic problems (p < 0.05), except the Guilt dimension of the SBI. Conclusion: We can conclude that the program was effective and that the study limitations should be improved in future studies

Towards the Rosetta Stone of planet formation

Transiting exoplanets (TEPs) observed just about 10 Myrs after formation of their host systems may serve as the Rosetta Stone for planet formation theories. They would give strong constraints on several aspects of planet formation, e.g. time-scales (planet formation would then be possible within 10 Myrs), the radius of the planet could indicate whether planets form by gravitational collapse (being larger when young) or accretion growth (being smaller when young). We present a survey, the main goal of which is to find and then characterise TEPs in very young open clusters.Comment: Poster contribution to Detection and Dynamics of Transiting Exoplanets (Haute Provence Observatory Colloquium, 23-27 August 2010

Rethinking Transnational Activism through Regional Perspectives: Reflections, Literatures and Cases

Copyright \ua9 The Author(s), 2024. Published by Cambridge University Press on behalf of the Royal Historical Society. This collectively authored article argues for a regional turn in the historical study of transnational activism. By considering not only pan-regional movements but also examples of borderland contexts, transregional connections and diasporic understandings of \u27region\u27, our discussion identifies fresh possibilities for investigating the evolution and functioning of transnational activism. Based on a Royal Historical Society-funded workshop held at and supported by Northumbria University, the article brings together insights from diverse locations and arenas of contestation. The first part considers literatures on three macro-regional settings - South Asia, Western Europe and Latin America - to illustrate the importance of distinctive regional contexts and constructs in shaping transnational activism and its goals. The second part turns to case studies of transnational activism in and beyond Eastern Europe, West Africa, the Caribbean and East Asia. In doing so, it explores very different notions of the regional to identify how transnational activism has both shaped and been shaped by these ideas. Taken together, the two parts highlight the role of regional identities and projects in challenging inequalities and external domination. Our analysis and examples indicate the possibilities of a regionally rooted approach for writing histories of transnational activism

Interior structure models of GJ 436b

GJ 436b is the first extrasolar planet discovered that resembles Neptune in mass and radius. The particularly interesting property of Neptune-sized planets is that their mass Mp and radius Rp are close to theoretical M-R relations of water planets. Given Mp, Rp, and equilibrium temperature, however, various internal compositions are possible. A broad set of interior structure models is presented here that illustrates the dependence of internal composition and possible phases of water occurring in presumably water-rich planets, such as GJ 436b on the uncertainty in atmospheric temperature profile and mean density. We show how the set of solutions can be narrowed down if theoretical constraints from formation and model atmospheres are applied or potentially observational constraints for the atmospheric metallicity Z1 and the tidal Love number k2. We model the interior by assuming either three layers (hydrogen-helium envelope, water layer, rock core) or two layers (H/He/H2O envelope, rocky core). For water, we use the equation of state H2O-REOS based on FT-DFT-MD simulations. Some admixture of H/He appears mandatory for explaining the measured radius. For the warmest considered models, the H/He mass fraction can reduce to 10^-3, still extending over ~0.7 REarth. If water occurs, it will be essentially in the plasma phase or in the superionic phase, but not in an ice phase. Metal-free envelope models have 0.02<k2<0.2, and the core mass cannot be determined from a measurement of k2. In contrast, models with 0.3<k2<0.82 require high metallicities Z1<0.89 in the outer envelope. The uncertainty in core mass decreases to 0.4 Mp, if k2>0.3, and further to 0.2 Mp, if k2>0.5, and core mass and Z1 become sensitive functions of k2. To further narrow the set of solutions, a proper treatment of the atmosphere and the evolution is necessary.Comment: 9 pages, accepted to A&