On p-hyperellipticity of doubly symmetric Riemann surfaces

Studying commuting symmetries of p-hyperelliptic Riemann surfaces, Bujalance and Costa found in [3] upper bounds for the degree of hyperellipticity of the product of commuting (M − q)- and (M − q')-symmetries, depending on their separabilities. Here, we find necessary and sufficient conditions for an integer p to be the degree of hyperellipticity of the product of two such symmetries, taking into account their separabilities. We also give some results concerning the existence and uniqueness of symmetries from which we obtain a series of important results of Natanzon concerning Mand (M − 1)-symmetries

Insight into the Leukemia Microenvironment and Cell-cell Interactions Using Flow Cytometry

Cancer cells, including leukemia cells, reside in a complex microenvironment, which influences biology and activity of the cells. The protective role of bone marrow stromal cells is already commonly recognized. Remodeling of stroma cell functions by leukemia cells is also well documented. In this respect, different routes of interactions were defined, such as direct cell-cell interactions or indirect cross talk, by release of soluble factors or vesicular particles containing proteins, RNAs and other molecules. Since intercellular communication seems to play a role in various biological processes, it might be important to conduct studies in co-culture systems, which at least mimic partially more physiological conditions, and enables this intercellular exchange to occur. Thus, it is crucial to improve analytical methods of investigation of co-cultured cells, to study their interactions and so to understand biology of leukemia in order to understand molecular mechanisms and offer novel therapeutic strategies. The present chapter outlines the importance of modern, multiparameter flow cytometry methods, which allow to analyze interactions between different types of cells within the leukemia microenvironment. Importantly, the proposed experimental setups can be easily transformed to study different cell types and different biological systems

Proteomic profile alterations in porcine conceptuses during early stages of development

The dynamic embryo development during the early stages of gestation requires precise molecular changes, including proteomic ones. We aimed to find unique proteins for porcine conceptuses specifically during the peri-implantation period, i.e. on days 15–16 of pregnancy. The proteomic profile of these conceptuses was compared with conceptuses at an earlier stage of the development, i.e. collected during maternal recognition of pregnancy on days 12–13 of pregnancy. The 2DE, gel image analysis, and MALDI TOF mass spectrometry were used 500 protein spots were annotated as common to conceptuses harvested during both studied periods. Proteomic profile of the conceptuses collected during the peri-implantation period contains 24 unique proteins. Identified unique for the peri-implantation period proteins are involved in adhesion processes, cadherin, and actin-binding, and actin filament organization, extracellular matrix organization, and cytoskeleton organization. Systemic analysis of identified proteins confirmed their involvement in cell adhesion and cytoskeletal organization as being two major affected functions. The unique proteins might be recognized as factors conditioning the proper peri-implantation embryo development and gaining competences for implantation. In further studies, BRCA1 might be considered as a candidate for a potential marker of embryonic competences for implantation in pigs.The work was funded by a grant from the National Science Centre, Poland (DEC-2012/05/N/NZ4/02343). We acknowledge support to S.S. from Qatar National Research Fund (QNRF) (NPRP9-453-3-089)

Spectres de vibration des systèmes contenant de l’acide nitrique anhydre

En vue de faciliter l’interprétation des spectres décrits dans le mémoire précédent, on a étudié par les mêmes méthodes les solutions concentrées de KNO3 et NH4NO3 dans l’acide nitrique anhydre et les solutions aqueuses concentrées d’acide nitrique.L’examen des bandes connues et des bandes nouvelles qui apparaissent dans les solutions concentrées, conduit à une nouvelle interprétation des observations antérieures.La bande 1 415 cm-1 observée dans le spectre IR de l’acide nitrique à 70 % ne peut être attribuée à NO3-, mais à la molécule HNO3 complexée par liaison hydrogène.L’étude de la bande OH de l’acide nitrique dans les mélanges HNO3 — CHCl3, conduit à une nouvelle interprétation du mode d’association de HNO3

Spectres de vibration des systèmes contenant de l’acide nitrique anhydre

L’association de l’acide nitrique et du 1,4-Dioxanne conduit à un composé d’addition cristallisable : 2 HNO3.C4H8O2. L’étude des spectres Raman et infrarouge des mélanges HNO3-l,4-Dioxanne, montre que la structure ionique C4H8O2H2++, 2 NO3- proposée antérieurement pour ce prétendu « nitrate », est incompatible avec les résultats obtenus. Les raisons de cette différence d’interprétation sont discutées

On p-hyperellipticity of doubly symmetric Riemann surfaces

Studying commuting symmetries of p-hyperelliptic Riemann surfaces, Bujalance and Costa found in [3] upper bounds for the degree of hyperellipticity of the product of commuting (M − q)- and (M − q')-symmetries, depending on their separabilities. Here, we find necessary and sufficient conditions for an integer p to be the degree of hyperellipticity of the product of two such symmetries, taking into account their separabilities. We also give some results concerning the existence and uniqueness of symmetries from which we obtain a series of important results of Natanzon concerning Mand (M − 1)-symmetries