The concept WHITE SILENCE in the “Northern stories” by Jack London

The article focuses on a specific extension of the concept WHITE SILENCE in the “Northern stories” by Jack London. The concept WHITE SILENCE is one of the most interesting concepts not only in the literary works of J. London, but also in American culture. Applying the statements of the concept layers structure, we discover that the figurative layer of the concept WHITE SILENCE consists of the ten conceptual features as “territorial area”, “ice”, “cold”, “snow”, “frost”, “silence”, “mental illnesses”, “famine”, “pain”, “physical death”. It also includes three microconcepts LANDSCAPE, NOTHERN NATURE, NOTHERN LIFE CONDITIONS. The most vivid means such as epithet, metaphor, intensification and personification in the “Northern stories” are used

Clinicians' and laboratory medicine specialists' views on laboratory demand management: a survey in nine European countries

Background Laboratory tests are an essential aspect of current medical practice and their use has grown exponentially. Several studies however have demonstrated inappropriate use of laboratory testing. This inappropriateness can lead to delayed or wrong diagnosis, negatively impacting patient safety and an increase in health care expenditure. The aim of the present small-scale survey was to obtain information on the current status of demand management in European laboratories, as well as the opinions of laboratory and clinical professionals in this regard. Methods Two surveys were developed, one for laboratory specialists and one for clinicians, covering information on current use, knowledge and opinions on the possible impact of different demand management strategies on patient outcome and health care costs. Additionally, we asked for the current state and willingness on collaboration of laboratory specialists and clinicians. Results One hundred and fifty responses, 72 laboratory specialists and 78 clinicians, from nine countries were received. Developing local ordering protocols/profiles in collaboration with clinicians was the most used strategy (80.3% of laboratories). Of clinicians, 85.6% considered measures to ensure appropriate use of tests necessary and 100% were interested in advice/information about their indication. Of the laboratory specialists 97.2% were either already participating or willing to participate in multidisciplinary groups on the appropriateness of test demand as were 60.3% of clinicians, and 85.9% of clinicians were interested in attending activities about laboratory test demand management. Conclusions The results of our survey show that tools to improve the appropriate use of laboratory tests are already regularly used today. Laboratory medicine specialists as well as clinicians are willing to undertake additional shared activities aimed at improving patient-centered laboratory diagnostic workup

Generation potential, distribution area and maturity of the Barents-Kara Sea source rocks

Identification of the source rock potential and distribution area is the most important stage of the basin analysis and oil, and gas reserves assessment. Based on analysis of the large geochemical and geological data base of the Petroleum geology department of the Lomonosov Moscow State University and integration of different-scale information (pyrolysis results and regional palaeogeographic maps), generation potential, distribution area and maturity of the main source rock intervals of the Barents-Kara Sea shelf are reconstructed. These source rocks wide distribute on the Barents-Kara Sea shelf and are characterized by lateral variability of generation potential and type of organic matter depending on paleogeography. During regional transgressions in Late Devonian, Early Permian, Middle Triassic and Late Jurassic, deposited source rocks with marine organic matter and excellent generation potential. However in the regression periods, during the short-term transgressions, formed Lower Carboniferous, Upper Permian, Induan, Olenekian and Late Triassic source rocks with mixed and terrestrial organic matter and good potential. Upper Devonian shales contain up to 20.6% (average – 3%) of marine organic matter, have an excellent potential and is predicted on the Eastern-Barents megabasin. Upper Devonian source rocks are in the oil window on the steps, platforms and monoclines, while are overmature in the basins. Lower Permian shale-carbonate source rock is enriched with marine organic matter (up to 4%, average – 1.4%) and has a good end excellent potential. Lower Permian source rocks distribute over the entire Barents shelf and also in the North-Kara basin (Akhmatov Fm). These rocks enter the gas window in the Barents Sea shelf, the oil window on the highs and platforms and are immature in the North-Kara basin. Middle Triassic shales contain up to 11.2% of organic matter, there is a significant lateral variability of the features: an excellent generation potential and marine organic matter on the western Barents Sea and poor potential and terrestrial organic matter in the eastern Barents Sea. Middle Triassic source rocks are in the oil window; in the depocenters it generates gas. Upper Jurassic black shales are enriched with marine and mixed organic matter (up to 27,9%, average – 7.3%) and have an excellent potential. On the most Barents-Kara Sea shelf, Upper Jurassic source rock are immature, but are in the oil window in the South-Kara basin and in the deepest parts of the Barents Sea shelf.publishedVersio

Нефтегазоматеринские толщи Баренцево-Карского шельфа: область распространения и свойства

Identification of the source rock potential and distribution area is the most important stage of the basin analysis and oil, and gas reserves assessment. Based on analysis of the large geochemical and geological data base of the Petroleum geology department of the Lomonosov Moscow State University and integration of different-scale information (pyrolysis results and regional palaeogeographic maps), generation potential, distribution area and maturity of the main source rock intervals of the Barents-Kara Sea shelf are reconstructed. These source rocks wide distribute on the Barents-Kara Sea shelf and are characterized by lateral variability of generation potential and type of organic matter depending on paleogeography. During regional transgressions in Late Devonian, Early Permian, Middle Triassic and Late Jurassic, deposited source rocks with marine organic matter and excellent generation potential. However in the regression periods, during the short-term transgressions, formed Lower Carboniferous, Upper Permian, Induan, Olenekian and Late Triassic source rocks with mixed and terrestrial organic matter and good potential. Upper Devonian shales contain up to 20.6% (average – 3%) of marine organic matter, have an excellent potential and is predicted on the Eastern-Barents megabasin. Upper Devonian source rocks are in the oil window on the steps, platforms and monoclines, while are overmature in the basins. Lower Permian shale-carbonate source rock is enriched with marine organic matter (up to 4%, average – 1.4%) and has a good end excellent potential. Lower Permian source rocks distribute over the entire Barents shelf and also in the North-Kara basin (Akhmatov Fm). These rocks enter the gas window in the Barents Sea shelf, the oil window on the highs and platforms and are immature in the North-Kara basin. Middle Triassic shales contain up to 11.2% of organic matter, there is a significant lateral variability of the features: an excellent generation potential and marine organic matter on the western Barents Sea and poor potential and terrestrial organic matter in the eastern Barents Sea. Middle Triassic source rocks are in the oil window; in the depocenters it generates gas. Upper Jurassic black shales are enriched with marine and mixed organic matter (up to 27,9%, average – 7.3%) and have an excellent potential. On the most Barents-Kara Sea shelf, Upper Jurassic source rock are immature, but are in the oil window in the South-Kara basin and in the deepest parts of the Barents Sea shelf

The role of European Federation of Clinical Chemistry and Laboratory Medicine Working Group for Preanalytical Phase in standardization and harmonization of the preanalytical phase in Europe

Patient safety is a leading challenge in healthcare and from the laboratory perspective it is now well established that preanalytical errors are the major contributor to the overall rate of diagnostic and therapeutic errors. To address this, the European Federation of Clinical Chemistry and Laboratory Medicine Working Group for Preanalytical Phase (EFLM WG-PRE) was established to lead in standardization and harmonization of preanalytical policies and practices at a European level. One of the key activities of the WG-PRE is the organization of the biennial EFLM-BD conference on the preanalytical phase to provide a forum for National Societies (NS) to discuss their issues. Since 2012, a year after the first Preanalytical phase conference, there has been a rapid growth in the number of NS with a working group engaged in preanalytical phase activities and there are now at least 19 countries that have one. As a result of discussions with NS at the third conference held in March 2015 five key areas were identified as requiring harmonisation. These were test ordering, sample transport and storage, patient preparation, sampling procedures and management of unsuitable specimens. The article below summarises the work that has and will be done in these areas. The goal of this initiative is to ensure the EFLM WG-PRE produces work that meets the needs of the European laboratory medicine community. Progress made in the identified areas will be updated at the next preanalytical phase conference and show that we have produced guidance that has enhanced standardisation in the preanalytical phase and improved patient safety throughout Europe

Joint EFLM-COLABIOCLI Recommendation for venous blood sampling

This document provides a joint recommendation for venous blood sampling of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE) and Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI). It offers guidance on the requirements for ensuring that blood collection is a safe and patient-centered procedure and provides practical guidance on how to successfully overcome potential barriers and obstacles to its widespread implementation. The target audience for this recommendation are healthcare staff members directly involved in blood collection. This recommendation applies to the use of a closed blood collection system and does not provide guidance for the blood collection with an open needle and syringe and catheter collections. Moreover, this document neither addresses patient consent, test ordering, sample handling and transport nor collection from children and unconscious patients. The recommended procedure is based on the best available evidence. Each step was graded using a system that scores the quality of the evidence and the strength of the recommendation. The process of grading was done at several face-To-face meetings involving the same mixture of stakeholders stated previously. The main parts of this recommendation are: 1) Pre-sampling procedures, 2) Sampling procedure, 3) Post-sampling procedures and 4) Implementation. A first draft of the recommendation was circulated to EFLM members for public consultation. WG-PRE-LATAM was also invited to comment the document. A revised version has been sent for voting on to all EFLM and COLABIOCLI members and has been officially endorsed by 33/40 EFLM and 21/21 COLABIOCLI members. We encourage professionals throughout Europe and Latin America to adopt and implement this recommendation to improve the quality of blood collection practices and increase patient and workers safety

Raccomandazione congiunta EFLM-COLABIOCLI per il prelievo di sangue venoso

This document provides a joint recommendation for venous blood sampling of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE) and Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI). It offers guidance on the requirements for ensuring that blood collection is a safe and patient-centered procedure and provides practical guidance on how to successfully overcome potential barriers and obstacles to its widespread implementation. The target audience for this recommendation are healthcare staff members directly involved in blood collection. This recommendation applies to the use of a closed blood collection system and does not provide guidance for the blood collection with an open needle and syringe and catheter collections. Moreover, this document neither addresses patient consent, test ordering, sample handling and transport nor collection from children and unconscious patients. The recommended procedure is based on the best available evidence. Each step was graded using a system that scores the quality of the evidence and the strength of the recommendation. The process of grading was done at several face-to-face meetings involving the same mixture of stakeholders stated previously. The main parts of this recommendation are: 1) Pre-sampling procedures, 2) Sampling procedure, 3) Postsampling procedures and 4) Implementation. A first draft of the recommendation was circulated to EFLM members for public consultation. WG-PRE-LATAM was also invited to comment the document. A revised version has been sent for voting on to all EFLM and COLABIOCLI members and has been officially endorsed by 33/40 EFLM and 21/21 COLABIOCLI members. We encourage professionals throughout Europe and Latin America to adopt and implement this recommendation to improve the quality of blood collection practices and increase patient and workers safety

Recommandations communes EFLM-COLABIOCLI relatives au prélèvement sanguin veineux

Ce document propose des recommandations pour le prélèvement sanguin veineux. Celles-ci ont été élaborées conjointement par le groupe de travail en charge de la phase pré-analytique (WG-PRE) de la Fédération européenne de chimie clinique et de médecine de laboratoire (EFLM) et le groupe de travail latino-américain pour la phase pré-analytique (WG-PRE-LATAM) de la Confédération latino-américaine de biochimie clinique (COLABIOCLI). Ce document propose des conseils sur les conditions requises permettant de garantir que la prise de sang est une procédure sûre et centrée sur le patient. Il fournit des conseils pratiques sur la manière de surmonter, avec succès, les obstacles potentiels et les barrières à sa mise en œuvre généralisée. Ces recommandations s’adressent aux professionnels de santé directement impliqués dans le prélèvement sanguin. Elles s’appliquent à l’utilisation de système dit « fermé » et ne concernent ni le prélèvement de sang utilisant un dispositif « à écoulement libre », ni les prélèvements à la seringue ou ceux utilisant des cathéters. De plus, ce document ne traite ni du consentement du patient, ni du choix des examens prescrits, ni de la manipulation et du transport des échantillons, ni du prélèvement chez les enfants et les patients inconscients. La procédure recommandée est basée sur les meilleures preuves disponibles. Chaque étape a été pondérée à l’aide d’un système qui évalue le niveau de la preuve et la force de la recommandation. Le processus de notation a été effectué lors de plusieurs réunions impliquant le même groupe d’intervenants qu’indiqué précédemment. Les principaux chapitres de cette recommandation sont les suivants : 1) Procédures précédant le prélèvement, 2) Prélèvement sanguin veineux, 3) Phase post-prélèvement, 4) Mise en œuvre des recommandations. Une première version de ces recommandations a été diffusée aux membres de l’EFLM pour consultation publique. Le WG-PRE-LATAM a également été invité à commenter le document. Une version révisée a été envoyée pour vote à tous les membres de l’EFLM et de COLABIOCLI. Il a été officiellement approuvé par 33 membres sur 40 pour l’EFLM et par 21 membres sur 21 pour COLABIOCLI. Nous encourageons les professionnels à travers l’Europe et l’Amérique latine à adopter et à mettre en œuvre ces recommandations pour améliorer la qualité des pratiques de prélèvements sanguins et pour améliorer la sécurité des patients et du personnel

Joint EFLM-COLABIOCLI recommendation for venous blood sampling

This document provides a joint recommendation for venous blood sampling of the European federation of clinical chemistry and laboratory medicine (EFLM) Working Group for preanalytical phase (WG-PRE) and Latin American working group for preanalytical phase (WG-PRE-LATAM) of the Latin America confederation of clinical biochemistry (COLABIOCLI). It offers guidance on the requirements for ensuring that blood collection is a safe and patient-centered procedure and provides practical guidance on how to successfully overcome potential barriers and obstacles to its widespread implementation. The target audience for this recommendation are healthcare staff members directly involved in blood collection. This recommendation applies to the use of a closed blood collection system and does not provide guidance for the blood collection with an open needle and syringe and catheter collections. Moreover, this document neither addresses patient consent, test ordering, sample handling and transport nor collection from children and unconscious patients. The recommended procedure is based on the best available evidence. Each step was graded using a system that scores the quality of the evidence and the strength of the recommendation. The process of grading was done at several face-to-face meetings involving the same mixture of stakeholders stated previously. The main parts of this recommendation are: 1) Pre-sampling procedures, 2) Sampling procedure, 3) Post-sampling procedures and 4) Implementation. A first draft of the recommendation was circulated to EFLM members for public consultation. WG-PRE-LATAM was also invited to comment the document. A revised version has been sent for voting on to all EFLM and COLABIOCLI members and has been officially endorsed by 33/40 EFLM and 21/21 COLABIOCLI members. We encourage professionals throughout Europe and Latin America to adopt and implement this recommendation to improve the quality of blood collection practices and increase patient and workers safety.status: publishe

Raccomandazione congiunta EFLM-COLABIOCLI per il prelievo di sangue venoso : [Joint EFLM-COLABIOCLI recommendation for venous blood sampling]

This document provides a joint recommendation for venous blood sampling of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE) and Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI). It offers guidance on the requirements for ensuring that blood collection is a safe and patient-centered procedure and provides practical guidance on how to successfully overcome potential barriers and obstacles to its widespread implementation. The target audience for this recommendation are healthcare staff members directly involved in blood collection. This recommendation applies to the use of a closed blood collection system and does not provide guidance for the blood collection with an open needle and syringe and catheter collections. Moreover, this document neither addresses patient consent, test ordering, sample handling and transport nor collection from children and unconscious patients. The recommended procedure is based on the best available evidence. Each step was graded using a system that scores the quality of the evidence and the strength of the recommendation. The process of grading was done at several face-to-face meetings involving the same mixture of stakeholders stated previously. The main parts of this recommendation are: 1) Pre-sampling procedures, 2) Sampling procedure, 3) Postsampling procedures and 4) Implementation. A first draft of the recommendation was circulated to EFLM members for public consultation. WG-PRE-LATAM was also invited to comment the document. A revised version has been sent for voting on to all EFLM and COLABIOCLI members and has been officially endorsed by 33/40 EFLM and 21/21 COLABIOCLI members. We encourage professionals throughout Europe and Latin America to adopt and implement this recommendation to improve the quality of blood collection practices and increase patient and workers safety