Sovereign wealth funds: much ado about some money

This perspective makes the point that sovereign wealth funds constitute only one of the pools of anonymous capital, and for that matter, not even one of the most important ones. However, the author recognizes that issues of national security are involved and require attention

How the EU can better protect the rule of law in its member states

The EU is in the process of adopting a new regulation to help protect the rule of law in member states. Drawing on the cases of Hungary and Poland, Nanette Neuwahl and Charles Kovacs argue that the proposed regulation would be a valuable addition, but that a somewhat revised litigation strategy of the European Commission could also help defend EU values

主权财富基金：许多关于金钱的纷扰

在本文看来，主权财富基金只构成匿名资本的一部分，甚至不是最重要的之一。但是，笔者认识到，涉及国家安全的问题是需要注意的

The Coding and Inter-Manual Transfer of Movement Sequences

The manuscript reviews recent experiments that use inter-manual transfer and inter-manual practice paradigms to determine the coordinate system (visual–spatial or motor) used in the coding of movement sequences during physical and observational practice. The results indicated that multi-element movement sequences are more effectively coded in visual–spatial coordinates even following extended practice, while very early in practice movement sequences with only a few movement elements and relatively short durations are coded in motor coordinates. Likewise, inter-manual practice of relatively simple movement sequences show benefits of right and left limb practice that involves the same motor coordinates while the opposite is true for more complex sequences. The results suggest that the coordinate system used to code the sequence information is linked to both the task characteristics and the control processes used to produce the sequence. These findings have the potential to greatly enhance our understanding of why in some conditions participants following practice with one limb or observation of one limb practice can effectively perform the task with the contralateral limb while in other (often similar) conditions cannot

Mars oxygen production system design

The design and construction phase is summarized of the Mars oxygen demonstration project. The basic hardware required to produce oxygen from simulated Mars atmosphere was assembled and tested. Some design problems still remain with the sample collection and storage system. In addition, design and development of computer compatible data acquisition and control instrumentation is ongoing

Bilan et perspectives sur la gestion des eaux pluviales à la parcelle sur le territoire des Hauts-de-Seine Points forts, réticences et axes d'amélioration

National audienceIn 2005, the département' council of Hauts-de-Seine approved its sewer system master-plan for the next 15 years. In a highly urbanised context, the département conducts a voluntary policy for stormwater control aimed at reducing combined sewer overflow and the flooding risks. To improve the efficiency of its policy in the Hauts-de-Seine county, urban managers and sewer system owners' commitment is needed. Therefore, the département has developed several tools ta promote a consistent policy for sustainable stormwater management. After seven years, the département has wished ta initiate a review of its policy through a series of interviews of its partners: local authorities and developers. These interviews have shown that stormwater regulation rules are now included in most municipalities' sewer system regulation documents and land use plans. Although many new buildings and developments were exemplary, it seems that some reticence sometime remains about stormwater source control and also access in private estates for checking the stormwater collecting system. Continuing a strong and long-lasting policy as well as mproving stormwater source control will contribute to update our sewer system master-plan.En 2005, le conseil général des Hauts-de-Seine approuvait son schéma départemental d'assainissement (SDA) pour les 15 années suivantes. Dans un contexte fortement urbanisé, ce document définit une politique en matière de maîtrise des eaux pluviales ayant pour objectif la protection des milieux naturels et la réduction des inondations par débordement de réseaux. Conscient de la nécessité d'impliquer l'ensemble des acteurs de l'urbanisme et de l'assainissement pour garantir l'efficacité de sa politique sur le territoire des Hauts-de-Seine, le département a développé un panel d'outils pour promouvoir la cohérence des politiques relatives à la gestion durable des eaux pluviales. Aujourd'hui, à mi-parcours de la mise en oeuvre du SDA 2005-2020, le département a souhaité engager une démarche d'évaluation de sa politique en menant une série d'entretiens auprès de ses partenaires: collectivités et aménageurs. Ces enquêtes ont permis de mettre en évidence des résultats concrets en matière d'intégration par les collectivités des prescriptions de maîtrise des eaux pluviales dans les règlements d'assainissement et les documents d'urbanisme et le développement de plusieurs projets d'aménagement exemplaires, mais ont également souligné l'existence persistante de nombreux freins pour une mise en oeuvre efficace des techniques alternatives et des contrôles des ouvrages de gestion des eaux pluviales dans les parcelles privées. La poursuite d'une politique forte et pérenne ainsi que l'esquisse de plusieurs propositions d'amélioration en matière de gestion des eaux pluviales alimenteront l'actualisation du SD

Outbreaks of Pneumocystis Pneumonia in 2 Renal Transplant Centers Linked to a Single Strain of Pneumocystis: Implications for Transmission and Virulence

By restriction fragment length polymorphism analysis, 2 outbreaks of Pneumocystis pneumonia in renal transplant patients in Europe were shown to be caused by the same strain of Pneumocystis; another outbreak in Japan was caused by a different strai

Activity of the tetrapyrrole regulator CrtJ is controlled by oxidation of a redox active cysteine located in the DNA binding domain

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92379/1/j.1365-2958.2012.08135.x.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/92379/2/MMI_8135_sm_fS1-S6,tS1.pd

Multifunctional proteins revealed by overlapping clustering in protein interaction network

Motivation: Multifunctional proteins perform several functions. They are expected to interact specifically with distinct sets of partners, simultaneously or not, depending on the function performed. Current graph clustering methods usually allow a protein to belong to only one cluster, therefore impeding a realistic assignment of multifunctional proteins to clusters

Decreased Survival of B Cells of HIV-viremic Patients Mediated by Altered Expression of Receptors of the TNF Superfamily

Human immunodeficiency virus (HIV) infection leads to numerous perturbations of B cells through mechanisms that remain elusive. We performed DNA microarray, phenotypic, and functional analyses in an effort to elucidate mechanisms of B cell perturbation associated with ongoing HIV replication. 42 genes were up-regulated in B cells of HIV-viremic patients when compared with HIV-aviremic and HIV-negative patients, the majority of which were interferon (IFN)-stimulated or associated with terminal differentiation. Flow cytometry confirmed these increases and indicated that CD21low B cells, enhanced in HIV-viremic patients, were largely responsible for the changes. Increased expression of the tumor necrosis factor (TNF) superfamily (TNFSF) receptor CD95 correlated with increased susceptibility to CD95-mediated apoptosis of CD21low B cells, which, in turn, correlated with HIV plasma viremia. Increased expression of BCMA, a weak TNFSF receptor for B lymphocyte stimulator (BLyS), on CD21low B cells was associated with a concomitant reduction in the expression of the more potent BLyS receptor, BAFF-R, that resulted in reduced BLyS binding and BLyS-mediated survival. These findings demonstrate that altered expression of genes associated with IFN stimulation and terminal differentiation in B cells of HIV-viremic patients lead to an increased propensity to cell death, which may have substantial deleterious effects on B cell responsiveness to antigenic stimulation