A novel acute phase rehabilitation approach: Vibration therapy in insular glioma patients

Acute phase rehabilitation has beneficial effects on functional results, activities of daily living, mobility and cognition in glioma patient. Two insular glioma patients had acute phase rehabilitation were presented in this study. The Karnofsky Performance Scale, The Stroke Rehabilitation Assesment of Movement Scale, the Berg Balance Scale, and the Functional Independence Measure were used to assess patients. While Case 1 was treated with Neurodevelopmental Therapy (Bobath approach) (12 sessions), Case 2 was treated with cervical vibration in addition to Neurodevelopmental Therapy (15 sessions). Besides observing positive developments in the balance and functional levels of the two cases after treatment, there was more improvement in the balance parameter of Case 2. As a result of the study, cervical vibration application in addition to the rehabilitation program of patients with insular tumor could be useful in terms of balance development. [Med-Science 2018; 7(2.000): 448-50

Investigation of the relationship between pain threshold and joint position sense in the cervical region

This study was performed to investigate whether there is a relationship between cervical region pain threshold and joint position sense (JPS) in healthy subjects. The subjects were 38 healthy volunteers in the Hacettepe University, Faculty of Health Sciences, Physiotherapy and Rehabilitation Department. Pain thresholds in the right and left cervical paravertebral regions of participants were assessed with a digital algometer (Wagner Instruments, Greenwich, USA). The JPS of the cervical region was assessed with the Cervical Range of Motion 3 (CROM 3) device. While the pain thresholds in the left and right cervical paravertebral regions increased, the JPS error levels in the cervical region of the extension direction decreased (right and left cervical paravertebral region p = 0.003 and r = -0.475, p = 0.020 and r = -0.377, respectively). At the end of this study, the position sense error was higher in the participants with a low pain threshold. In participants in which the pain threshold is lower, prematurely stimulated pain receptors can decrease JPS by causing suppression of proprioceptive receptors. JPS should be assessed in individuals who define pain in the neck region. According to the result of this study, it is necessary to improve JPS in patients with neck pain, or healthy individuals who have lower pain threshold may be able to avoid neck pain when they receive appropriate proprioceptive training to improve their JPS. In conclusion, when healthy individuals were included in proprioceptive training, it was observed that neck pain could be prevented in the early period. [Med-Science 2019; 8(1.000): 97-101

Mesenchymal Stem Cells and Nano-Bioceramics for Bone Regeneration

Orthopedic disorders and trauma usually result in bone loss. Bone grafts are widely used to replace this tissue. Bone grafts excluding autografts unfortunately have disadvantages like evoking immune response, contamination and rejection. Autografts are of limited sources and optimum biomaterials that can replace bone have been searched for several decades. Bioceramics, which have the similar inorganic structure of natural bone, are widely used to regenerate bone or coat metallic implants. As people continuously look for a higher life quality, there are developments in technology almost everyday to meet their expectations. Nanotechnology is one of such technologies and it attracts everyone's attention in biomaterial science. Nano scale biomaterials have many advantages like larger surface area and higher biocompatibility and these properties make them more preferable than micro scale. Also, stem cells are used for bone regeneration besides nano-bioceramics due to their differentiation characteristics. This review covers current research on nano-bioceramics and mesenchymal stem cells and their role in bone regeneration

Gait And Glasgow Coma Scale Scores Can Predict Functional Recovery In Patients With Traumatic Brain Injury

Fifty-one patients with mild (n = 14), moderate (n = 10) and severe traumatic brain injury (n = 27) received early rehabilitation. Level of consciousness was evaluated using the Glasgow Coma Score. Functional level was determined using the Glasgow Outcome Score, whilst mobility was evaluated using the Mobility Scale for Acute Stroke. Activities of daily living were assessed using the Barthel Index. Following Bobath neurodevelopmental therapy, the level of consciousness was significantly improved in patients with moderate and severe traumatic brain injury, but was not greatly influenced in patients with mild traumatic brain injury. Mobility and functional level were significantly improved in patients with mild, moderate and severe traumatic brain injury. Gait recovery was more obvious in patients with mild traumatic brain injury than in patients with moderate and severe traumatic brain injury. Activities of daily living showed an improvement but this was insignificant except for patients with severe traumatic brain injury. Nevertheless, complete recovery was not acquired at discharge. Multiple regression analysis showed that gait and Glasgow Coma Scale scores can be considered predictors of functional outcomes following traumatic brain injury.PubMedWo

Do Stabilization Exercises Increase The Effects Of Lumbar Facet Radiofrequency Denervation?

AIM: To investigate the effects of lumbar stabilization exercises on pain severity, functional disability, and physical performance after two weeks following radiofrequency denervation in patients with lumbar facet joint syndrome (LFJS). MATERIAL and METHODS: Thirty-nine patients diagnosed with LFJS and had radiofrequency denervation were assigned to study and control groups. The study group (n=20) received a six-week stabilization exercise program and was informed about spine biomechanics, while the control group (n=19) received only informations about spine biomechanics. Pain severity with visual analogue scale, perceived disability with Oswestry disability index, physical performance with physical performance tests and gait speed test were applied before and after radiofrequency denervation, and after six weeks of intervention program. RESULTS: Despite the similar improvements were shown in terms of all outcomes in both groups following radiofrequency denervation (p>0.05), the improvements were more in favor of study group after six week intervention program (p<0.05). CONCLUSION: These results indicate that radiofrequency denervation is effective in improving the pain, disability, and physical performance in patients with LFJS and this effect is further enhanced by the stabilization exercises following this procedure. Adding stabilization exercises to radiofrequency denervation yielded positive outcomes and these exercise are strongly advised in physiotherapy and rehabilitation program.WoSScopu

Oxidant and Antioxidant Balance in Patients with Childhood Non-Cystic Fibrosis-Related Bronchiectasis

Objective: To evaluate the role of the oxidant and antioxidant balance in the pathogenesis and prognosis of non-cystic fibrosis bronchiectasis (non-CF BE) in children. Materials and Methods: Twenty-nine children with non-CF BE were enrolled between June 2009 and October 2010. Thirty healthy children were enrolled as controls. Paraoxonase 1 (PON1), total oxidant status (TOS), and total antioxidant status (TAS) serum levels were measured in controls and in patients when stable and at acute exacerbation. Results: PON1 and TAS levels were lower in patients at acute exacerbation than in controls (P=0.05 and P=0.01, respectively). TOS levels indicative of oxidative stress were higher, and TAS/TOS levels were lower, in immune-deficient patients than control group (P=0.008 and P=0.01, respectively). TAS levels and PON1/TOS ratio were significantly lower in patients with moderate-severe bronchiectasis than in patients with mild bronchiectasis (P=0.043 and P=0.03, respectively). Conclusion: Oxidative stress was increased and antioxidant capacity decreased in patients with non-CF BE during the exacerbation period. Antioxidant treatment in patients with non-CF BE, especially in patients with immunodeficiency and/or with moderate-severe bronchiectasis, could be helpful to reduce the frequency and severity of the attacks by reducing oxidative stress-induced damage, ultimately contributing to a better prognosis

Treatment of male hypogonadism partially reverses oxidative stress in patients with hypogonadism

There are some studies regarding the presence/absence of oxidative stress in patients with hypogonadism with limited number of parameters. We aimed to investigate the effects of male hypogonadism and its treatment on oxidative stress parameters. Thirteen male patients with hypogonadotropic hypogonadism and 20 healthy subjects were involved in the study. Patients with hypogonadism were evaluated before and after six months of therapy. Markers indicating lipid and protein oxidation, total oxidant status (TOS) and total anti-oxidant capacity (TAC) were evaluated. Control subjects had significantly higher serum testosterone levels in comparison to hypogonadal patients before the treatment period. After the treatment of hypogonadism serum testosterone levels increased significantly. Myeloperoxidase (MPO) activity, levels of advanced oxidation protein products (AOPP), total lipid hydroperoxide and protein carbonyl compounds (PCC) were similar between the control subjects and the patient group before treatment. Pyrrolized protein and TOS were significantly lower and thiol levels and TAC were significantly higher in the control subjects than in patients with hypogonadism. Treatment of hypogonadism resulted in a significant decrease in AOPP levels while a significant increase was determined in TAC. No significant change was found in MPO activity. In conclusion, patients with hypogonadism have an increased status of oxidative stress which is at least partially improved after appropriate therapy

Effects of exercise and electrical stimulation on lumbar stabilization in asymptomatic subjects: A comparative study

WOS: 000322248400006PubMed ID: 23893140BACKGROUND AND OBJECTIVES: Segmental stabilization training and electrical stimulation are used as a treatment for patients with low back pain. There is limited information on the efficacy of two interventions in the literature. In this study, the efficacy of the two interventions on the multifidus muscle activation and fatigue, segmental stabilization training and electrical stimulation, were examined and compared. MATERIAL AND METHODS: Our sample consists of 30 asymptomatic individuals, randomly assigned to one of three groups: the group that was given segmental stabilization training, the group that was given electrical stimulation and the control group that received no treatment. The muscle activity and fatigability of the multifidus were recorded by the surface electromyography before and after the intervention. RESULTS: No difference is detected for any of the multifidus muscle activation and fatigue characteristics either within or between groups. CONCLUSION: Both techniques did not improve multifidus activation capacity. An effort at submaximal and maximal level affects and increases the activity of multifidus