ΣΥΜΠΕΡΑΣΜΑΤΑ ΕΚ ΤΗΣ ΒΙΟΧΗΜΙΚΗΣ ΜΕΛΕΤΗΣ ΤΗΣ ΧΟΛΗΣ ΛΙΘΙΑΣΙΚΩΝ ΚΑΙ ΜΗ ΑΣΘΕΝΩΝ ΕΝ ΕΛΛΑΔΙ.

Η ΠΑΡΟΥΣΑ ΕΡΓΑΣΙΑ, Η ΟΠΟΙΑ ΕΙΝΑΙ Η ΠΡΩΤΗ ΕΚΠΟΝΗΘΕΙΣΑ ΕΝ ΕΛΛΑΔΙ ΗΤΙΣ ΕΜΕΤΡΗΣΕΝ ΤΑ ΣΤΟΙΧΕΙΑ ΤΗΣ ΧΟΛΗΣ ΠΡΟΣ ΤΟΝ ΣΚΟΠΟΝ ΤΗΣ ΔΙΕΡΕΥΝΗΣΕΩΣ ΤΗΣ ΒΙΟΧΗΜΕΙΑΣ ΤΗΣ ΧΟΛΗΣ ΚΑΙ ΤΗΣ ΛΙΘΟΓΕΝΕΣΕΩΣ ΕΠΙ ΤΟΥ ΕΛΛΗΝΙΚΟΥ ΠΛΗΘΥΣΜΟΥ, ΕΓΙΝΕΝ ΠΡΟΣ ΕΠΙΒΕΒΑΙΩΣΙΝΤΩΝ ΟΣΩΝ ΥΠΟ ΤΩΝ ADMIRAND ΚΑΙ SMALL ΥΠΕΣΤΗΡΙΧΘΗΣΑΝ ΑΠΟ ΤΩ ΕΤΕΙ 1968. ΠΡΟΣ ΤΟΥΤΟ, ΑΦ'ΟΥ ΑΝΕΠΤΥΧΘΗΣΑΝ ΔΙΕΞΟΔΙΚΩΣ ΑΙ ΒΙΟΧΗΜΙΚΑΙ ΙΔΙΟΤΗΤΕΣ ΤΩΝ ΣΤΟΙΧΕΙΩΝ ΤΗΣ ΧΟΛΗΣ ΚΑΙ Ο ΠΑΘΟΦΥΣΙΟΛΟΓΙΚΟΣ ΜΗΧΑΝΙΣΜΟΣ ΤΗΣ ΛΙΘΟΓΕΝΕΣΕΩΣ, ΕΞΗΤΑΣΘΗΣΑΝ ΤΥΧΑΙΑ ΔΕΙΓΜΑΤΑ ΧΟΛΗΣ ΛΙΘΙΑΣΙΚΩΝ ΚΑΙ ΦΥΣΙΟΛΟΓΙΚΩΝ ΑΣΘΕΝΩΝ ΟΣΟΝ ΑΦΟΡΑ ΤΗΝ ΑΝΑΛΟΓΙΑ ΤΩΝ ΧΟΛΙΚΩΝ ΑΛΑΤΩΝ ΧΟΛΗΣΤΕΡΟΛΗΣ ΚΑΙ ΦΩΣΦΟΛΙΠΙΔΙΩΝ ΕΝ ΤΗ ΧΟΛΗ. ΤΑΥΤΑ ΕΔΕΙΞΑΝ, ΟΤΙ ΕΠΙ ΧΟΛΟΛΙΘΙΑΣΕΩΣ ΠΡΑΓΜΑΤΙ ΥΦΙΣΤΑΤΑΙ ΔΙΑΤΑΡΑΧΗ ΤΗΣ ΣΧΕΣΕΩΣ ΑΥΤΩΝ ΚΑΙ ΟΤΙ ΕΙΝΑΙΑΥΤΗ ΑΠΑΡΑΙΤΗΤΟΣ ΠΡΟΥΠΟΘΕΣΙΣ ΔΙΑ ΤΟΝ ΣΧΗΜΑΤΙΣΜΟΝ ΧΟΛΟΛΙΘΩΝ. ΕΠΙΣΗΣ ΑΝΕΠΤΥΧΘΗΣΑΝ ΟΙ ΠΡΟΔΙΑΘΕΣΙΚΟΙ ΠΑΡΑΓΟΝΤΕΣ ΟΙ ΣΥΜΒΑΛΛΟΝΤΕΣ ΕΙΣ ΤΗΝ ΔΗΜΙΟΥΡΓΙΑΝ ΤΗΣ ΧΟΛΟΛΙΘΙΑΣΕΩΣ ΚΑΙ ΕΙΧΟΜΕΝ ΕΝΔΕΙΞΕΙΣ ΟΤΙ Ο ΣΑΚΧΑΡΩΔΗΣ ΔΙΑΒΗΤΗΣ, Η ΠΑΧΥΣΑΡΚΙΑ ΚΑΙ Η ΕΓΚΥΜΟΣΥΝΗ ΔΗΜΙΟΥΡΓΟΥΝ ΛΙΑΝ ΥΠΕΡΚΕΚΟΡΕΣΜΕΝΑΣ ΕΙΣ ΧΟΛΗΣΤΕΡΟΛΗΝ ΧΟΛΑΣ ΚΑΙ ΩΣ ΕΚ ΤΟΥΤΟΥ ΜΕΓΑΛΥΤΕΡΑΝ ΕΠΙΠΤΩΣΙΝ ΤΗΣ ΝΟΣΟΥ ΕΙΣ ΤΑΣ ΚΑΤΑΣΤΑΣΕΙΣ ΑΥΤΑΣ

Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Patients With Abdominal Aortic Aneurysm and Its Alterations After Treatment

Purpose: The aim of the present study was to investigate a potential difference on the arterial stiffness among aneurysm patients and non-aneurysm controls, as well as to explore potential changes between patients treated either with endovascular or open repair. Materials and Methods: A 110 patients with an infrarenal AAA were prospectively enrolled in this study. Fifty-six patients received an EVAR, whereas 54 patients received an open surgical repair. Moreover, 103 gender and age-matched subjects without AAA served as controls. The cardio-ankle vascular index (CAVI) was applied for measurement of the arterial stiffness. Results: CAVI values were statistically higher in the AAA patients when compared with control subjects. Although at 48 hours postoperatively the CAVI values were increased in both groups when compared to baseline values, the difference in CAVI had a tendency to be higher in the open group compared to the endovascular group. At 6 months of follow up the CAVI values returned to the baseline for the patients of the open repair group. However, in the endovascular group CAVI values remained higher when compared with the baseline values. Conclusion: Patients with AAAs demonstrated a higher value of CAVI compared to healthy controls. A significant increase of arterial stiffness in both groups during the immediate postoperative period was documented. The increase in arterial stiffness remained significant at 6 months in EVAR patients. Further studies are needed to elucidate the impact of a decreased aortic compliance after stentgraft implantation on the cardiac function of patients with AAA

Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Patients With Abdominal Aortic Aneurysm and Its Alterations After Treatment

Purpose: The aim of the present study was to investigate a potential difference on the arterial stiffness among aneurysm patients and non-aneurysm controls, as well as to explore potential changes between patients treated either with endovascular or open repair. Materials and Methods: A 110 patients with an infrarenal AAA were prospectively enrolled in this study. Fifty-six patients received an EVAR, whereas 54 patients received an open surgical repair. Moreover, 103 gender and age-matched subjects without AAA served as controls. The cardio-ankle vascular index (CAVI) was applied for measurement of the arterial stiffness. Results: CAVI values were statistically higher in the AAA patients when compared with control subjects. Although at 48 hours postoperatively the CAVI values were increased in both groups when compared to baseline values, the difference in CAVI had a tendency to be higher in the open group compared to the endovascular group. At 6 months of follow up the CAVI values returned to the baseline for the patients of the open repair group. However, in the endovascular group CAVI values remained higher when compared with the baseline values. Conclusion: Patients with AAAs demonstrated a higher value of CAVI compared to healthy controls. A significant increase of arterial stiffness in both groups during the immediate postoperative period was documented. The increase in arterial stiffness remained significant at 6 months in EVAR patients. Further studies are needed to elucidate the impact of a decreased aortic compliance after stentgraft implantation on the cardiac function of patients with AAA

Endovascular treatment of a vertebral artery pseudoaneurysm in a drug user

A 26-year-old drug abuser who presented with sepsis was found to have a pseudoaneurysm in the left vertebral artery. This aneurysm was presumed to be post-traumatic, since the patient reported multiple attempts to inject drugs in the left jugular vein 15 days prior to admission. The pseudoaneurysm was treated effectively with stent-graft placement