10,328 research outputs found
Self-reported domain-specific and accelerometer-based physical activity and sedentary behaviour in relation to psychological distress among an urban Asian population
Background: The interpretation of previous studies on the association of physical activity and sedentary behaviour with psychological health is limited by the use of mostly self-reported physical activity and sedentary behaviour, and a focus on Western populations. We aimed to explore the association of self-reported and devise-based measures of physical activity and sedentary behaviour domains on psychological distress in an urban multi-ethnic Asian population.
Methods: From a population-based cross-sectional study of adults aged 18-79 years, data were used from an overall sample (n = 2653) with complete self-reported total physical activity/sedentary behaviour and domain-specific physical activity data, and a subsample (n = 703) with self-reported domain-specific sedentary behaviour and accelerometry data. Physical activity and sedentary behaviour data were collected using the Global Physical Activity Questionnaire (GPAQ), a domain-specific sedentary behaviour questionnaire and accelerometers. The Kessler Screening Scale (K6) and General Health Questionnaire (GHQ-12) were used to assess psychological distress. Logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals, adjusted for socio-demographic and lifestyle characteristics.
Results: The sample comprised 45.0% men (median age = 45.0 years). The prevalence of psychological distress based on the K6 and GHQ-12 was 8.4% and 21.7%, respectively. In the adjusted model, higher levels of self-reported moderate-to-vigorous physical activity (MVPA) were associated with significantly higher odds for K6 (OR = 1.47 [1.03-2.10]; p-trend = 0.03) but not GHQ-12 (OR = 0.97 [0.77-1.23]; p-trend = 0.79), when comparing the highest with the lowest tertile. Accelerometry-assessed MVPA was not significantly associated with K6 (p-trend = 0.50) nor GHQ-12 (p-trend = 0.74). The highest tertile of leisure-time physical activity, but not work- or transport-domain activity, was associated with less psychological distress using K6 (OR = 0.65 [0.43-0.97]; p-trend = 0.02) and GHQ-12 (OR = 0.72 [0.55-0.93]; p-trend = 0.01). Self-reported sedentary behaviour was not associated with K6 (p-trend = 0.90) and GHQ-12 (p-trend = 0.33). The highest tertile of accelerometry-assessed sedentary behaviour was associated with significantly higher odds for K6 (OR = 1.93 [1.00-3.75]; p-trend = 0.04), but not GHQ-12 (OR = 1.34 [0.86-2.08]; p-trend = 0.18).
Conclusions: Higher levels of leisure-time physical activity and lower levels of accelerometer-based sedentary behaviour were associated with lower psychological distress. This study underscores the importance of assessing accelerometer-based and domain-specific activity in relation to mental health, instead of solely focusing on total volume of activity
Toughening in electrospun fibrous scaffolds
Electrospun scaffolds mimic the microstructure of structural collagenous tissues and have been widely used in tissue engineering applications. Both brittle cracking and ductile failure have been observed in scaffolds with similarly random fibrous morphology. Finite element analysis can be used to qualitatively examine the mechanics of these differing failure mechanisms. The finite element modeling demonstrates that the noncontinuum deformation of the network structure results in fiber bundle formation and material toughening. Such toughening is accommodated by varying fiber properties, including allowing large failure strains and progressive damage of the fibers.The authors acknowledge the support from the Ministry of Higher Education Malaysia, Khaow
Tonsomboon, Daniel Strange, and Anne Bahnweg.This is the final published version. It first appeared at http://scitation.aip.org/content/aip/journal/aplmater/3/1/10.1063/1.4901450
Noncommutative field gas driven inflation
We investigate early time inflationary scenarios in an Universe filled with a
dilute noncommutative bosonic gas at high temperature. A noncommutative bosonic
gas is a gas composed of bosonic scalar field with noncommutative field space
on a commutative spacetime. Such noncommutative field theories was recently
introduced as a generalization of quantum mechanics on a noncommutative
spacetime. As key features of these theories are Lorentz invariance violation
and CPT violation. In the present study we use a noncommutative bosonic field
theory that besides the noncommutative parameter shows up a further
parameter . This parameter controls the range of the
noncommutativity and acts as a regulator for the theory. Both parameters play a
key role in the modified dispersion relations of the noncommutative bosonic
field, leading to possible striking consequences for phenomenology. In this
work we obtain an equation of state for the
noncommutative bosonic gas relating pressure and energy density , in
the limit of high temperature. We analyse possible behaviours for this gas
parameters , and , so that , which
is the region where the Universe enters an accelerated phase.Comment: Reference added. Version to appear in Journal of Cosmology and
Astroparticle Physics - JCA
Control of sleep by a network of cell cycle genes
Sleep is essential for health and cognition, but the molecular and neural mechanisms of sleep regulation are not well understood. We recently reported the identification of TARANIS (TARA) as a sleep-promoting factor that acts in a previously unknown arousal center in Drosophila. tara mutants exhibit a dose-dependent reduction in sleep amount of up to âŒ60%. TARA and its mammalian homologs, the Trip-Br (Transcriptional Regulators Interacting with PHD zinc fingers and/or Bromodomains) family of proteins, are primarily known as transcriptional coregulators involved in cell cycle progression, and contain a conserved Cyclin-A (CycA) binding homology domain. We found that tara and CycA synergistically promote sleep, and CycA levels are reduced in tara mutants. Additional data demonstrated that Cyclin-dependent kinase 1 (Cdk1) antagonizes tara and CycA to promote wakefulness. Moreover, we identified a subset of CycA expressing neurons in the pars lateralis, a brain region proposed to be analogous to the mammalian hypothalamus, as an arousal center. In this Extra View article, we report further characterization of tara mutants and provide an extended discussion of our findings and future directions within the framework of a working model, in which a network of cell cycle genes, tara, CycA, and Cdk1, interact in an arousal center to regulate sleep.This work was supported by a grant from the National Institutes of Health (R01NS086887 to K.K.) and predoctoral fellowships from the Portuguese Foundation for Science and Technology (SFRH/BD/51726/2011 to D.J.S.A and SFRH/BD/52321/2013 to D.R.M)
Electronic Structure of Electron-doped Sm1.86Ce0.14CuO4: Strong `Pseudo-Gap' Effects, Nodeless Gap and Signatures of Short Range Order
Angle resolved photoemission (ARPES) data from the electron doped cuprate
superconductor SmCeCuO shows a much stronger pseudo-gap
or "hot-spot" effect than that observed in other optimally doped -type
cuprates. Importantly, these effects are strong enough to drive the
zone-diagonal states below the chemical potential, implying that d-wave
superconductivity in this compound would be of a novel "nodeless" gap variety.
The gross features of the Fermi surface topology and low energy electronic
structure are found to be well described by reconstruction of bands by a
order. Comparison of the ARPES and optical data from
the sample shows that the pseudo-gap energy observed in optical data is
consistent with the inter-band transition energy of the model, allowing us to
have a unified picture of pseudo-gap effects. However, the high energy
electronic structure is found to be inconsistent with such a scenario. We show
that a number of these model inconsistencies can be resolved by considering a
short range ordering or inhomogeneous state.Comment: 5 pages, 4 figure
HIPAD - A Hybrid Interior-Point Alternating Direction algorithm for knowledge-based SVM and feature selection
We consider classification tasks in the regime of scarce labeled training
data in high dimensional feature space, where specific expert knowledge is also
available. We propose a new hybrid optimization algorithm that solves the
elastic-net support vector machine (SVM) through an alternating direction
method of multipliers in the first phase, followed by an interior-point method
for the classical SVM in the second phase. Both SVM formulations are adapted to
knowledge incorporation. Our proposed algorithm addresses the challenges of
automatic feature selection, high optimization accuracy, and algorithmic
flexibility for taking advantage of prior knowledge. We demonstrate the
effectiveness and efficiency of our algorithm and compare it with existing
methods on a collection of synthetic and real-world data.Comment: Proceedings of 8th Learning and Intelligent OptimizatioN (LION8)
Conference, 201
Tunable spin-selective loading of a silicon spin qubit
The remarkable properties of silicon have made it the central material for
the fabrication of current microelectronic devices. Silicon's fundamental
properties also make it an attractive option for the development of devices for
spintronics and quantum information processing. The ability to manipulate and
measure spins of single electrons is crucial for these applications. Here we
report the manipulation and measurement of a single spin in a quantum dot
fabricated in a silicon/silicon-germanium heterostructure. We demonstrate that
the rate of loading of electrons into the device can be tuned over an order of
magnitude using a gate voltage, that the spin state of the loaded electron
depends systematically on the loading voltage level, and that this tunability
arises because electron spins can be loaded through excited orbital states of
the quantum dot. The longitudinal spin relaxation time T1 is measured using
single-shot pulsed techniques and found to be ~3 seconds at a field of 1.85
Tesla. The demonstration of single spin measurement as well as a long spin
relaxation time and tunability of the loading are all favorable properties for
spintronics and quantum information processing applications.Comment: 4 pages, 3 figures, Supplemental Informatio
A Wave Function Describing Superfluidity in a Perfect Crystal
We propose a many-body wave function that exhibits both diagonal and
off-diagonal long-range order. Incorporating short-range correlations due to
interatomic repulsion, this wave function is shown to allow condensation of
zero-point lattice vibrations and phase rigidity. In the presence of an
external velocity field, such a perfect crystal will develop non-classical
rotational inertia, exhibiting the supersolid behavior. In a sample calculation
we show that the superfluid fraction in this state can be as large as of order
0.01 in a reasonable range of microscopic parameters. The relevance to the
recent experimental evidence of a supersolid state by Chan and Kim is
discussed.Comment: final version to be published in Journal of Statistical Mechanics:
Theory and Experimen
An application of hybrid life cycle assessment as a decision support framework for green supply chains
In an effort to achieve sustainable operations, green supply chain management has become an important area for firms to concentrate on due to its inherent involvement with all the processes that provide foundations to successful business. Modelling methodologies of product supply chain environmental assessment are usually guided by the principles of life cycle assessment (LCA). However, a review of the extant literature suggests that LCA techniques suffer from a wide range of limitations that prevent a wider application in real-world contexts; hence, they need to be incorporated within decision support frameworks to aid environmental sustainability strategies. Thus, this paper contributes in understanding and overcoming the dichotomy between LCA model development and the emerging practical implementation to inform carbon emissions mitigation strategies within supply chains. Therefore, the paper provides both theoretical insights and a practical application to inform the process of adopting a decision support framework based on a LCA methodology in a real-world scenario. The supply chain of a product from the steel industry is considered to evaluate its environmental impact and carbon âhotspotsâ. The study helps understanding how operational strategies geared towards environmental sustainability can be informed using knowledge and information generated from supply chain environmental assessments, and for highlighting inherent challenges in this process
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