3,452 research outputs found
The Affective Impact of Financial Skewness on Neural Activity and Choice
Few finance theories consider the influence of “skewness” (or large and asymmetric but unlikely outcomes) on financial choice. We investigated the impact of skewed gambles on subjects' neural activity, self-reported affective responses, and subsequent preferences using functional magnetic resonance imaging (FMRI). Neurally, skewed gambles elicited more anterior insula activation than symmetric gambles equated for expected value and variance, and positively skewed gambles also specifically elicited more nucleus accumbens (NAcc) activation than negatively skewed gambles. Affectively, positively skewed gambles elicited more positive arousal and negatively skewed gambles elicited more negative arousal than symmetric gambles equated for expected value and variance. Subjects also preferred positively skewed gambles more, but negatively skewed gambles less than symmetric gambles of equal expected value. Individual differences in both NAcc activity and positive arousal predicted preferences for positively skewed gambles. These findings support an anticipatory affect account in which statistical properties of gambles—including skewness—can influence neural activity, affective responses, and ultimately, choice
Poly(dimethylsiloxane)-poly(ethylene oxide)-heparin block copolymers II: Surface characterization and in vitro assessments
Amphiphilic block copolymers containing poly(dimethylsiloxane), poly(ethylene oxide), as well as heparin-coated glass beads and tubes were evaluated for the amounts and activities of surface-immobilized heparin. Because the amphiphilic copolymer system is thermodynanmcally predicted to demonstrate low-energy phase enrichment on the surfaces of aircast films, studies were also undertaken to understand the in vitro results. Solvent-cast copolymer films have a heterogeneous microphase-separated structure according to transmission electron micrographs. Wilhelmy plate contact angle analysis indicates significant surface restructuring occurs upon hydration. Attenuated total reflectance infrared spectroscopy studies of the desiccated and hydrated films at two different sampling depths show compositional heterogeneity as a function of depth, as well as near surface restructuring allowing surface enrichment of the high-energy segments following contact with water. Significant concentrations of heparin are detected on the surface of these coatings by toluidine blue assays. In addition, a portion of the surface-bound heparin maintains its original bioactivity as determined by recalification times, thrombin times, and Factor Xa assays. These substrates were also tested for platelet adhesion and activation reactions in vitro using polymer-coated beads in rabbit platelet-rich plasma. Heparinized polymers promoted low levels of platelet adhesion and serotonin release. Surface concentrations of heparin from bioactivity assays were then correlated with platelet adhesion and the extent of platelet release to assess the efficacy of this heparin-immobilized copolymer as a blood-compatible material or coating
Quark Coulomb Interactions and the Mass Difference of Mirror Nuclei
We study the Okamoto-Nolen-Schiffer (ONS) anomaly in the binding energy of
mirror nuclei at high density by adding a single neutron or proton to a quark
gluon plasma. In this high-density limit we find an anomaly equal to two-thirds
of the Coulomb exchange energy of a proton. This effect is dominated by quark
electromagnetic interactions---rather than by the up-down quark mass
difference. At normal density we calculate the Coulomb energy of neutron matter
using a string-flip quark model. We find a nonzero Coulomb energy because of
the neutron's charged constituents. This effect could make a significant
contribution to the ONS anomaly.Comment: 4 pages, 2 figs. sub. to Phys. Rev. Let
Secondary Eclipse Photometry of WASP-4b with Warm Spitzer
We present photometry of the giant extrasolar planet WASP-4b at 3.6 and 4.5
micron taken with the Infrared Array Camera on board the Spitzer Space
Telescope as part of Spitzer's extended warm mission. We find secondary eclipse
depths of 0.319+/-0.031% and 0.343+/-0.027% for the 3.6 and 4.5 micron bands,
respectively and show model emission spectra and pressure-temperature profiles
for the planetary atmosphere. These eclipse depths are well fit by model
emission spectra with water and other molecules in absorption, similar to those
used for TrES-3 and HD 189733b. Depending on our choice of model, these results
indicate that this planet has either a weak dayside temperature inversion or no
inversion at all. The absence of a strong thermal inversion on this highly
irradiated planet is contrary to the idea that highly irradiated planets are
expected to have inversions, perhaps due the presence of an unknown absorber in
the upper atmosphere. This result might be explained by the modestly enhanced
activity level of WASP-4b's G7V host star, which could increase the amount of
UV flux received by the planet, therefore reducing the abundance of the unknown
stratospheric absorber in the planetary atmosphere as suggested in Knutson et
al. (2010). We also find no evidence for an offset in the timing of the
secondary eclipse and place a 2 sigma upper limit on |ecos(omega)| of 0.0024,
which constrains the range of tidal heating models that could explain this
planet's inflated radius.Comment: 8 pages, 7 figures (some in color), accepted for publication in Ap
A New 24 micron Phase Curve for upsilon Andromedae b
We report the detection of 24 micron variations from the planet-hosting
upsilon Andromedae system consistent with the orbital periodicity of the
system's innermost planet, upsilon And b. We find a peak-to-valley phase curve
amplitude of 0.00130 times the mean system flux. Using a simple model with two
hemispheres of constant surface brightness and assuming a planetary radius of
1.3 Jupiter radii gives a planetary temperature contrast of >900 K and an
orbital inclination of >28 degrees. We further report the largest phase offset
yet observed for an extrasolar planet: the flux maximum occurs ~80 degrees
before phase 0.5. Such a large phase offset is difficult to reconcile with most
current atmospheric circulation models. We improve on earlier observations of
this system in several important ways: (1) observations of a flux calibrator
star demonstrate the MIPS detector is stable to 10^-4 on long timescales, (2)
we note that the background light varies systematically due to spacecraft
operations, precluding use of this background as a flux calibrator (stellar
flux measured above the background is not similarly affected), and (3) we
calibrate for flux variability correlated with motion of the star on the MIPS
detector. A reanalysis of our earlier observations of this system is consistent
with our new result.Comment: Submitted to ApJ. 15 pages, 6 figures, 4 table
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