Search for neutrinos from transient sources with the ANTARES telescope and optical follow-up observations

The ANTARES telescope has the opportunity to detect transient neutrino sources, such as gamma-ray bursts, core-collapse supernovae, flares of active nuclei... To enhance the sensitivity to these sources, we have developed a new detection method based on the optical follow-up of "golden" neutrino events such as neutrino doublets coincident in time and space or single neutrinos of very high energy. The ANTARES Collaboration has therefore implemented a very fast on-line reconstruction with a good angular resolution. These characteristics allow to trigger an optical telescope network; since February 2009. ANTARES is sending alert trigger one or two times per month to the two 25 cm robotic telescope of TAROT. This follow-up of such special events would not only give access to the nature of the sources but also improves the sensitivity for transient neutrino sources.Comment: 3 pages, 3 figures, Proceedings of the 31st ICRC, Lodz, Polan, July 200

Quasi-two-dimensional Fermi surfaces of the heavy-fermion superconductor Ce2_2PdIn8_8

We report low-temperature de Haas-van Alphen (dHvA) effect measurements in magnetic fields up to 35 T of the heavy-fermion superconductor Ce$_2$PdIn$_8$. The comparison of the experimental results with band-structure calculations implies that the 4$f$ electrons are itinerant rather than localized. The cyclotron masses estimated at high field are only moderately enhanced, 8 and 14 $m_0$, but are substantially larger than the corresponding band masses. The observed angular dependence of the dHvA frequencies suggests quasi-two-dimensional Fermi surfaces in agreement with band-structure calculations. However, the deviation from ideal two dimensionality is larger than in CeCoIn$_5$, with which Ce$_2$PdIn$_8$ bears a lot of similarities. This subtle distinction accounts for the different superconducting critical temperatures of the two compounds.Comment: accepted to Phys. Rev.

SWI/SNF regulates a transcriptional programme that induces senescence to prevent liver cancer

Oncogene-induced senescence (OIS) is a potent tumour suppressor mechanism. To identify senescence regulators relevant to cancer, we screened an shRNA library targeting genes deleted in hepatocellular carcinoma (HCC). Here, we describe how knockdown of the SWI/SNF component ARID1B prevents OIS and cooperates with RAS to induce liver tumours. ARID1B controls p16INK4a and p21CIP1a transcription but also regulates DNA damage, oxidative stress and p53 induction, suggesting that SWI/SNF uses additional mechanisms to regulate senescence. To systematically identify SWI/SNF targets regulating senescence, we carried out a focused shRNA screen. We discovered several new senescence regulators including ENTPD7, an enzyme that hydrolyses nucleotides. ENTPD7 affects oxidative stress, DNA damage and senescence. Importantly, expression of ENTPD7 or inhibition of nucleotide synthesis in ARID1B-depleted cells results in re-establishment of senescence. Our results identify novel mechanisms by which epigenetic regulators can affect tumor progression and suggest that pro-senescence therapies could be employed against SWI/SNF-mutated cancers

The ultra-long GRB 111209A - II. Prompt to afterglow and afterglow properties

The "ultra-long" Gamma Ray Burst GRB 111209A at redshift z=0.677, is so far the longest GRB ever observed, with rest frame prompt emission duration of ~4 hours. In order to explain the bursts exceptional longevity, a low metallicity blue supergiant progenitor has been invoked. In this work, we further investigate this peculiar burst by performing a multi-band temporal and spectral analysis of both the prompt and the afterglow emission. We use proprietary and publicly available data from Swift, Konus Wind, XMM-Newton, TAROT as well as from other ground based optical and radio telescopes. We find some peculiar properties that are possibly connected to the exceptional nature of this burst, namely: i) an unprecedented large optical delay of 410+/-50 s is measured between the peak epochs of a marked flare observed also in gamma-rays after about 2 ks from the first Swift/BAT trigger; ii) if the optical and X-ray/gamma-ray photons during the prompt emission share a common origin, as suggested by their similar temporal behavior, a certain amount of dust in the circumburst environment should be introduced, with rest frame visual dust extinction of AV=0.3-1.5 mag; iii) at the end of the X-ray "steep decay phase" and before the start of the X-ray afterglow, we detect the presence of a hard spectral extra power law component never revealed so far. On the contrary, the optical afterglow since the end of the prompt emission shows more common properties, with a flux power law decay with index alpha=1.6+/-0.1 and a late re-brightening feature at 1.1 day. We discuss our findings in the context of several possible interpretations given so far to the complex multi-band GRB phenomenology. We also attempt to exploit our results to further constrain the progenitor nature properties of this exceptionally long GRB, suggesting a binary channel formation for the proposed blue supergiant progenitor.Comment: ApJ accepted. Revised version with substantial adjustments, the main results remain unchange

The VLTI/MIDI view on the inner mass loss of evolved stars from the Herschel MESS sample

The mass-loss process from evolved stars is a key ingredient for our understanding of many fields of astrophysics, including stellar evolution and the chemical enrichment of the interstellar medium via stellar yields. One the main unsolved questions is the geometry of the mass-loss process. Taking advantage of the results from the Herschel Mass loss of Evolved StarS (MESS) programme, we initiated a coordinated effort to characterise the geometry of mass loss from evolved red giants at various spatial scales. For this purpose we used the MID-infrared interferometric Instrument (MIDI) to resolve the inner envelope of 14 asymptotic giant branch stars (AGBs) in the MESS sample. In this contribution we present an overview of the interferometric data collected within the frame of our Large Programme, and we also add archive data for completeness. We studied the geometry of the inner atmosphere by comparing the observations with predictions from different geometric models. Asymmetries are detected for five O-rich and S-type, suggesting that asymmetries in the N band are more common among stars with such chemistry. We speculate that this fact is related to the characteristics of the dust grains. Except for one star, no interferometric variability is detected, i.e. the changes in size of the shells of non-mira stars correspond to changes of the visibility of less than 10%. The observed spectral variability confirms previous findings from the literature. The detection of dust in our sample follows the location of the AGBs in the IRAS colour-colour diagram: more dust is detected around oxygen-rich stars in region II and in the carbon stars in region VII. The SiC dust feature does not appear in the visibility spectrum of UAnt and SSct, which are two carbon stars with detached shells. This finding has implications for the theory of SiC dust formation.Comment: 43 pages, 31 figures; accepted for publication in Astronomy & Astrophysics. Abstract shortened for compilation reasons. Metadata correcte

The historical vanishing of the Blazhko effect of RR Lyr from GEOS and Kepler surveys

RR Lyr is one of the most studied variable stars. Its light curve has been regularly monitored since the discovery of the periodic variability in 1899. Analysis of all observed maxima allows us to identify two primary pulsation states defined as pulsation over a long (P0 longer than 0.56684 d) and a short (P0 shorter than 0.56682 d) primary pulsation period. These states alternate with intervals of 13-16 yr, and are well defined after 1943. The 40.8 d periodical modulations of the amplitude and the period (i.e. Blazhko effect) were noticed in 1916. We provide homogeneous determinations of the Blazhko period in the different primary pulsation states. The Blazhko period does not follow the variations of P0 and suddenly diminished from 40.8 d to around 39.0 d in 1975. The monitoring of these periodicities deserved and deserves a continuous and intensive observational effort. For this purpose we have built dedicated, transportable and autonomous small instruments, Very Tiny Telescopes (VTTs), to observe the times of maximum brightness of RR Lyr. As immediate results the VTTs recorded the last change of P0 state in mid-2009 and extended the time coverage of the Kepler observations, thus recording a maximum O-C amplitude of the Blazhko effect at the end of 2008, followed by the historically smallest O-C amplitude in late 2013. This decrease is still ongoing and VTT instruments are ready to monitor the expected increase in the next few years.Comment: 10 pages, 6 figures. Accepted for publication in MNRAS. Contents of appendix B may be requested to first autho