323 research outputs found

    Job Strain and Well-being of Teaching Professionals: An Empirical Investigation

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    The aim of the current study was to examine job strain and well-being in a group of male and female teaching professionals. The main objectives of the current study were to (i) Examine the difference between male teachers with low job strain and female teachers with low job strain on general well-being. (ii) Examine the difference between male teachers with high job strain and female teachers with high job strain on general well-being. (iii) Examine the difference between male teachers with low job strain and male teachers with high job strain on general well-being and (iv) Examine the difference between female teachers with low job strain and female teachers with high job strain on general well-being. A sample of 100 senior secondary teachers were selected from one of the Central Universities at Aligarh City using convenience sampling method of 32 were male and 58 were female teachers. The measures used were PGI Well-being scale (Moudgil et al, 1986) and Job Strain Questionnaire (Singh, 1989). The data were analyzed using descriptive statistics like mean and SD and inferential statistics like t-test. The findings of the current work indicate that mental health of males is better than of their female counterparts. The findings also indicate that high job strain effects the mental health of both the groups and male teachers are influenced more than females on their well-beings. Finally, significant difference was not found between the mean scores of female teachers with low job strain and high job strain on their general well-being. The study has implications for stress management programs for the teachers at senior secondary level to enhance their well-being and specific job related performanc

    Compound heterozygosity for a whole gene deletion and p.R124C mutation in CYP21A2 causing nonclassic congenital adrenal hyperplasia

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    We present a family with 2 members who received long-term steroid treatment for presumed classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, until molecular testing revealed nonclassic CAH, not necessarily requiring treatment. A 17-year-old male presented to our clinic on glucocorticoid and mineralocorticoid treatment for classic CAH. He was diagnosed at 4 years of age based on mild-moderate elevations of 17-hydroxyprogesterone (17-OHP) and adrenocorticotropic hormone (ACTH), but without evidence of precocious adrenarche/puberty. Due to his diagnosis, his clinically asymptomatic 3-year-old sister was tested and also found to have elevated ACTH and 17-OHP levels and was started on glucocorticoids for classic CAH. Family history revealed a healthy sibling who had no biochemical evidence of CAH and consanguineous healthy parents. We questioned the diagnosis of classic CAH and performed an ACTH1-24 stimulation test, which showed a level of 17-OHP in the borderline range between classic and nonclassic CAH. Molecular testing, using sequencing and multiplex ligation-dependent probe amplification analysis of CYP21A2, revealed that both affected siblings were compound heterozygotes for a whole-gene deletion and a, likely pathogenic (nonclassical), sequence variant, p.R124C. The asymptomatic father had the same genotype, while the mother showed one deleted copy and 2 active copies, making her an asymptomatic carrier. Our report demonstrates the importance of molecular testing in atypical cases of CAH, as well as the importance of both sequencing and deletion analysis. The results of molecular testing should be interpreted in clinical context, and treatment should be prescribed according to guidelines when available

    HOW ADVERTISING INFLUENCES YOUR CHOICES AND PURCHASING BEHAVIOUR WHILE SELECTING TOOTHPASTE

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    From television to wall murals, advertising is digital, ubiquitous and a powerful force shaping attitudes and behaviour in today's world. Owing to the rising consumer demands across products and services; the upsurge in competition across markets and companies vying for larger market share, advertisements, more precisely manipulative advertisements have become prevalent and the only means of generating revenues for companies that influence in ways we don't even realise.Keywords: Advertising, Purchasing, Advertising Standards Authority, Toothpast

    Distributed File Sharing and Retrieval Model for Cloud Virtual Environment

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    Cloud-based storage services are multiplying and are being adapted mostly for data storage. At the same time, many potential problems pertaining to data storage and security are being addressed. This research provides the architecture for splitting user data and the solution in retrieving different data chunks, stored on different cloud storages. By doing this, not only the load on a single server is reduced but security and storage are efficiently used. Data would be stored and retrieved in slices, hence the chances of data forgery are diminishing. File processing will be faster as split parts would be fetched from different clouds, enabling parallel processing

    Estimation in a Competing Risks Proportional Hazards Model Under Length-biased Sampling With Censoring

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    International audienceWhat population does the sample represent? The answer to this question is of crucial importance when estimating a survivor function in duration studies. As is well-known, in a stationary population, survival data obtained from a cross-sectional sample taken from the population at time t0t_0 represents not the target density f(t)f(t) but its length-biased version proportional to tf(t)tf(t), for t>0t>0. The problem of estimating survivor function from such length-biased samples becomes more complex, and interesting, in presence of competing risks and censoring. This paper lays out a sampling scheme related to a mixed Poisson process and develops nonparametric estimators of the survivor function of the target population assuming that the two independent competing risks have proportional hazards. Two cases are considered: with and without independent consoring before length biased sampling. In each case, the weak convergence of the process generated by the proposed estimator is proved. A well-known study of the duration in power for political leaders is used to illustrate our results. Finally, a simulation study is carried out in order to assess the finite sample behaviour of our estimators

    The profile of head injuries and traumatic brain injury deaths in Kashmir

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    This study was conducted on patients of head injury admitted through Accident & Emergency Department of Sher-i-Kashmir Institute of Medical Sciences during the year 2004 to determine the number of head injury patients, nature of head injuries, condition at presentation, treatment given in hospital and the outcome of intervention. Traumatic brain injury (TBI) deaths were also studied retrospectively for a period of eight years (1996 to 2003)

    Social marketing and healthy eating : Findings from young people in Greece

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    This document is the Accepted Manuscript version. The final publication is available at Springer via http://dx.doi.org/10.1007/s12208-013-0112-xGreece has high rates of obesity and non-communicable diseases owing to poor dietary choices. This research provides lessons for social marketing to tackle the severe nutrition-related problems in this country by obtaining insight into the eating behaviour of young adults aged 18–23. Also, the main behavioural theories used to inform the research are critically discussed. The research was conducted in Athens. Nine focus groups with young adults from eight educational institutions were conducted and fifty-nine participants’ views towards eating habits, healthy eating and the factors that affect their food choices were explored. The study found that the participants adopted unhealthier nutritional habits after enrolment. Motivations for healthy eating were good health, appearance and psychological consequences, while barriers included lack of time, fast-food availability and taste, peer pressure, lack of knowledge and lack of family support. Participants reported lack of supportive environments when deciding on food choices. Based on the findings, recommendations about the development of the basic 4Ps of the marketing mix, as well as of a fifth P, for Policy are proposedPeer reviewe

    MYORG-related disease is associated with central pontine calcifications and atypical parkinsonism

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    Objective: To identify the phenotypic, neuroimaging, and genotype-phenotype expression of MYORG mutations. Methods: Using next-generation sequencing, we screened 86 patients with primary familial brain calcification (PFBC) from 60 families with autosomal recessive or absent family history that were negative for mutations in SLC20A2, PDGFRB, PDGBB, and XPR1. In-depth phenotyping and neuroimaging investigations were performed in all cases reported here. Results: We identified 12 distinct deleterious MYORG variants in 7 of the 60 families with PFBC. Overall, biallelic MYORG mutations accounted for 11.6% of PFBC families in our cohort. A heterogeneous phenotypic expression was identified within and between families with a median age at onset of 56.4 years, a variable combination of parkinsonism, cerebellar signs, and cognitive decline. Psychiatric disturbances were not a prominent feature. Cognitive assessment showed impaired cognitive function in 62.5% of cases. Parkinsonism associated with vertical nuclear gaze palsy was the initial clinical presentation in 1/3 of cases and was associated with central pontine calcifications. Cerebral cortical atrophy was present in 37% of cases. Conclusions: This large, multicentric study shows that biallelic MYORG mutations represent a significant proportion of autosomal recessive PFBC. We recommend screening MYORG mutations in all patients with primary brain calcifications and autosomal recessive or negative family history, especially when presenting clinically as atypical parkinsonism and with pontine calcification on brain CT
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