282 research outputs found
Studies on Genetic Variability and Heritability in Bulb Onion (Allium cepa L.) in North-Western Plains of India
A study on genetic variability, heritability and genetic advance was carried out in bulb onion for 13 traits using 43 accessions. The range of variation was highest for bolting (0 to 51.30%), followed by days to maturity (110 to 155 days) and bulb weight (44 to 87.03g). Values for phenotypic coefficient of variation were higher than corresponding genotypic coefficient of variation for all the characters studied. Higher heritability estimates were obtained for plant height, leaf length, days to maturity, number of scales per bulb, polar diameter, equatorial diameter and TSS. Bolting, bulb weight, neck-to-bulb ratio and the lachrymatory factor showed moderate heritability, while, lowest values were observed for leaf girth and number of leaves per plant. Genetic advance varied from 0.06 to 21.82 for leaf girth and bolting, respectively
Prevalence of Paramphistomum cervi in different sheep breeds of Balochistan (Pakistan)
The prevalence of Paramphistomum cervi infestation in Balochi, Babrik and Harnai sheep breeds from Balochistan (Pakistan) was studied during September to December 2010. For this purpose, rumen of slaughtered sheep in Quetta City and surroundings (n=1,200) were examined. Results showed significant differences (
An unusual coordination polymer containing Cu+ ions and featuring possible Cu⋯Cu `cuprophilic' interactions: poly[di-μ-chlorido-(μ4-3,5-diaminobenzoato-κ4O:O′:N:N′)tricopper(I)(3 Cu—Cu)]
We thank the Higher Education Commission of Pakistan (grant No. 1-3/PM-PDFP-II/2006/22) for financial support.Peer reviewedPublisher PD
Morbidity and mortality of paediatric burns patients at Maputo Central Hospital, Mozambique
Background: The incidence of paediatric burn injuries is increasing in Africa. Paediatric burn injuries are among the leading causes of preventable morbidity and mortality in sub-Saharan Africa. Research on the morbidity and mortality in this setting is much needed.Methods: We conducted a prospective questionnaire-based analysis of paediatric burn patients presenting to the Maputo Central Hospital during a five-month period. Interviews were conducted with the children's caretakers by 2 paediatric surgery residents and 1 paediatrician at the Eduardo Mondlane Medical School in Maputo, with the aid of nursing staff.Results: Questionnaires were completed for 66 patients. Most burns occurred from scald injuries (n = 46), particularly from cooking (n = 27) and bathwater (n = 19), followed by fire injuries (n = 16). Burns occurred more frequently in the afternoon (n = 26) and morning (n = 23). Many patients reported no adult caretaker present at the time of the burn injury (n = 24). Most burns were grade II (n = 49). Nearly half of the patients received a blood transfusion (n = 30). One-third of the patients underwent operative surgical debridement (n = 21). Skin grafting was performed on a subset of these patients (n = 13). A large number of patients developed a wound infection (n = 39). All deaths occurred in patients who were admitted to the paediatric intensive care unit and had sepsis (n = 9). The mean total body surface area (TBSA) of burn deaths was 37% (range 20% to 50%), and many deaths were secondary to fire burns (6 of 9; 66.7%).Conclusions: Most paediatric burn injuries occur in association with domestic activities, such as cooking and bathing. Adult caretakers are frequently not present at the time of the burn injury. Mortality rates are high, especially for large body surface area burns caused by fire. Educational programmes may help reduce the incidence of burns and the associated morbidity and mortality. The improvement and expansion of emergency and intensive burn care services may help to improve survival.Keywords: burns; morbidity; mortality; paediatrics; paediatric surgery; Mozambiqu
Hydrothermal synthesis and crystal structure of poly[bis- (μ3-3,4-diaminobenzoato) manganese], a layered coordination polymer
Acknowledgements The EPSRC National Crystallography Service (University of Southampton) is thanked for the intensity data collection. Funding information We thank the Higher Education Commission of Pakistan (grant No. 1–3/PM-PDFP-II/2006/22) for financial supportPeer reviewedPublisher PD
Irreversible magnetization in thin YBCO films rotated in external magnetic field
The magnetization M of a thin YBaCuO film is measured as a function of the
angle between the applied field H and the c-axis. For fields above
the first critical field, but below the Bean's field for first penetration H*,
M is symmetric with respect to and the magnetization curves for
forward and backward rotation coincide. For H>H* the curves are asymmetric and
they do not coincide. These phenomena have a simple explanation in the
framework of the Bean critical state model.Comment: 14 pages, 7 PostScript figure
ESTABLISHING A PLATFORM FOR SPRAY DRYING INHALABLE VACCINES IN SOUTH AFRICA
Mycobacterium bovis BCG is the current vaccine for tuberculosis (TB). However, BCG as it is currently administered shows highly variable efficacy in protecting adults against TB. The natural route of infection of TB is via inhalation of bacilli-containing aerosols and it is postulated that immunization by the natural route of infection may lead to a greater immunity given the fact that the lungs are the primary target of infection. By eliciting both local and systemic immune responses, it is anticipated that an inhaled form of BCG will offer greater protection against pulmonary TB.
Current commercial BCG vaccine preparations are filled as bacterial suspensions in vials, dried through lyophilization and stabilized through refrigeration with a one year shelf life. However, freeze-dried BCG does not exhibit a particle form conducive for delivery via the aerosol route and must be injected. Spray drying studies by Harvard University and Medicine in Need (MEND) scientists have demonstrated that BCG could be spray dried into a viable aerosol with up to 1 year of stability under refrigerated conditions, with the potential for room temperature stability.
To support the further preclinical development of the BCG aerosol for application in the developing world, MEND established a state-of-the-art Biosafety level 3 spray drying facility with local expertise in South Africa, where the vaccine will be produced for an IND-enabling toxicology study meeting OECD Good Laboratory Practice (GLP) requirements. Frozen BCG bulk is spray dried and the resulting dry powder is characterized in terms of viability and aerosol properties. The dried BCG aerosol is then aseptically filled into capsules using a semi-automatic filling device for delivery using a low-cost hand-held inhaler.
In conclusion, the spray drying technology was successfully transferred from Harvard University to the MEND facility in Pretoria. MEND is developing local expertise and infrastructure to support further preclinical and clinical development of BCG for inhalation
Correlating the density and refractive index of ternary liquid mixtures
DATA AVAILABILITY : Excel spreadsheets containing the full data sets with calculations are available from the
corresponding author.Some physical properties of ideal solutions, e.g. the molar volume and the molar refraction,
vary linearly with composition. Others can be expressed, either as ratios or as products of
two other properties which vary with composition in this way. It is postulated that the nonideal
behaviour of real solutions can be adequately modelled by substituting these linear
functions with higher order Scheffé polynomials. A suite of such models is presented for
which the parameters are fully determined by knowledge of pure component properties and
binary behaviour. Their binary data representation ability, and capacity to predict ternary
properties, was tested using density and refractive index data for the acetic acid–ethanolwater
ternary system as well as fourteen additional ternary data sets. Model performance
was ranked on the basis of the Akaike Information criterion. With respect to predicting
ternary density and refractive index behaviour from knowledge of binary data, it was found
that lower-order models outperformed higher order models.The Deutsche Forschungsgemeinschaft (DFG) and the German Academic Exchange Service (DAAD). Open access funding provided by University of Pretoria.http://link.springer.com/journal/10953am2024Chemical EngineeringSDG-09: Industry, innovation and infrastructur
Two neutrino positron double beta decay of Cd for transition
The two neutrino positron double beta decay of Cd for 0
0 transition has been studied in the Hartree-Fock-Bogoliubov model in
conjunction with the summation method. In the first step, the reliability of
the intrinsic wave functions of Cd and Pd nuclei has been
tested by comparing the theoretically calculated results for yrast spectra,
reduced : transition probabilities, quadrupole moments
and gyromagnetic factors with the available experimental
data. In the second step, the nuclear transition matrix element and
the half-life for 0 0 transition have been
calculated with these wave functions. Moreover, we have studied the effect of
deformation on nuclear transition matrix element MComment: 20 page
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