314 research outputs found

    Venture Capital Sector in Pakistan: Ratio Analysis Approach for Financial Performance Assessment

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    The purpose of study is to rank the venture capital companies operating in Pakistan during the period of 2006-2009 on the base of their financial performance. Ratio analysis technique was used to rank the venture capital companies using profitability / efficiency ratios and total assets as proxies of financial performance. This study concludes that TRG Pakistan Limited is at first in ranking on the bases of return on assets (ROA), return on equity (ROE), and total assets, and at second on the base of earnings per share (EPS). AMZ Ventures Limited is at first on the base of earnings per share (EPS), at second in ranking on the bases of return on assets (ROA), return on equity (ROE), and total assets. TMT Ventures Limited is third on the bases of all ratios, and total assets. This is the first attempt that was made with an objective to facilitate the students, investors and management of company with useful information regarding financial performance of all venture capital companies operating in Pakistan

    Evaluation of the root and canal morphology of mandibular first permanent molars in a sample of Pakistani population by cone-beam computed tomography

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    Objective: To evaluate the root canal morphology of permanent mandibular first molars using Cone Beam Computed Tomography. Methods: The retrospective study was done at Aga Khan University Hospital, Karachi, and comprised medical records of patients who visited the dental clinics from December 2016 to March 2017. Mandibular first permanent molars were evaluated on Cone Beam Computed Tomography images. Frequency distribution of Vertucci\u27s classification was determined, and so was the association between Vertucci\u27s classifications and gender. SPSS 20 was used for data analysis. Results: A total of 142 mandibular first permanent molars were evaluated on 78 Cone Beam Computed Tomography images. The most common Vertucci\u27s classification was Type IV for mesial root 86(60.56%) and Type I for distal root 63(44%). There was no difference in the two genders for root canal morphology (p\u3e0.05). Conclusions: Type IV Vertucci\u27s were prevalent in the mesial root and Type I were common in the distal root of permanent mandibular first molars

    Design optimisation for stent manufacture

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    Intravascular stents of various designs are currently used to prop open diseased arteries and there is evidence that different stent geometries have different in-stent restenosis rates. The majority of commercially available stents are designed generically to fit all individuals. Recent advances in imaging and catheter technologies, however, allow measurement of lesion shape and stiffness. Incorporating patient specific data into the stent design process could enable the development of customised stents. Considering the variety of lesion types, it is envisaged that better outcomes will be achieved if a stent is custom designed in such a way that it has variable radial stiffness longitudinally to hold the varying pressure of plaque and healthy artery at the same time while maintaining an acceptable lumen diameter. This type of operation is suitable for topology optimisation potentially allowing for optimal material distribution of a stent. The primary aim of this research is to develop new stent designs for a set of plaque types and investigate the final radius of the lumen after stent implantation. Stent geometries were obtained by topology optimisation for minimised compliance under different stenosis levels and plaque materials. Three types of stenosis levels by area, i.e. 30%, 40% and 50% with each type having three different plaque material properties i.e. calcified, cellular and hypocellular were studied. The optimisation results were transformed to clear design concepts and their performance was evaluated by implanting them in their respective stenosed artery types using finite element analysis. The results were compared with a generic stent in similar arteries, which showed that the new designs showed less recoil. In the hardest (calcified) of plaques studied, topology optimised designs overall resulted in 2%, 2% and 6% residual area stenosis compared to 10%, 29% and 35% from the generic design in arteries with 30%, 40% and 50% stenosis respectively. It was shown that higher material distribution resulted in the central region of the stent in order to resist implantation recoil due to higher plaque compressive loads. Additive manufacturing (AM) was utilised to validate the computational approach used in this thesis. This work provides a proof of concept for stents tailored to specific lesions in order to minimise recoil and maintain a patent lumen in stenotic arteries

    Femtocellular Aspects on UMTS Architecture Evolution

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    Recent advancement in System Architecture Evolution (SAE) has opened the door for the deployment of femtocells on a large scale. Deployment of femtocells in the existing macrocell networks and in 4G networks will significantly increase because femtocell offers increase coverage and capacity in both home and office environments. Hence it is likely that these low-power home based access points are going to change the landscape of mobile technology and the networking business in the coming years. This thesis work offers a deep insight into the mobile communication system architecture evolution and typically explains femtocellular aspects in the evolution of Universal Mobile Telecommunication System (UMTS) architecture. This research work mainly focuses on architectural variations of 3G and 4G femtocells along with the operational functionality of Local IP Access (LIPA). LIPA introduces the functionality in femtocells to access a home Local Area Network (LAN) and enable customers to use the Internet through Internet-enabled devices. Hence users have the capability to have simultaneous access to the operator's network as well as having access to their own home LAN. The way LIPA works is explained How it can create problems for femtocells deployment and what solutions LIPA offers for providing easy femtocell configurations. With the help of the extensive study about LIPA-enabled femtocells, different scenarios are discussed and two different solutions are proposed both for 3G and 4G femtocells. For maintaining higher data rates, 3G and 4G systems require a good coverage area to increase system performance. But research results suggest that two-thirds of consumers suffer from inadequate indoor signal penetration which actually leads to poor coverage for consumers, who do not enjoy the full data capacity as guaranteed. 4G systems will facilitate high speed data services, but poor coverage and interference will definitely diminish the quality of real-time applications and will significantly slow down high speed data services. The aim of this thesis is to propose di_erent logical indoor 4G femtocell architectures based on 3GPP specifications that will also be capable of providing LIPA functionality

    Design optimisation for stent manufacture

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    Intravascular stents of various designs are currently used to prop open diseased arteries and there is evidence that different stent geometries have different in-stent restenosis rates. The majority of commercially available stents are designed generically to fit all individuals. Recent advances in imaging and catheter technologies, however, allow measurement of lesion shape and stiffness. Incorporating patient specific data into the stent design process could enable the development of customised stents. Considering the variety of lesion types, it is envisaged that better outcomes will be achieved if a stent is custom designed in such a way that it has variable radial stiffness longitudinally to hold the varying pressure of plaque and healthy artery at the same time while maintaining an acceptable lumen diameter. This type of operation is suitable for topology optimisation potentially allowing for optimal material distribution of a stent. The primary aim of this research is to develop new stent designs for a set of plaque types and investigate the final radius of the lumen after stent implantation. Stent geometries were obtained by topology optimisation for minimised compliance under different stenosis levels and plaque materials. Three types of stenosis levels by area, i.e. 30%, 40% and 50% with each type having three different plaque material properties i.e. calcified, cellular and hypocellular were studied. The optimisation results were transformed to clear design concepts and their performance was evaluated by implanting them in their respective stenosed artery types using finite element analysis. The results were compared with a generic stent in similar arteries, which showed that the new designs showed less recoil. In the hardest (calcified) of plaques studied, topology optimised designs overall resulted in 2%, 2% and 6% residual area stenosis compared to 10%, 29% and 35% from the generic design in arteries with 30%, 40% and 50% stenosis respectively. It was shown that higher material distribution resulted in the central region of the stent in order to resist implantation recoil due to higher plaque compressive loads. Additive manufacturing (AM) was utilised to validate the computational approach used in this thesis. This work provides a proof of concept for stents tailored to specific lesions in order to minimise recoil and maintain a patent lumen in stenotic arteries
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