35 research outputs found

    Impact Analysis of Advising and Counseling System for Under-graduation Students in Bangladesh

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    In the development process of a student, counseling and advising system plays a crucial role. By providing proper counseling through empathetic relationship, we can learn about the problems of a student. With the help of this learning, we can find out all of the negative issues that are happening with the students. Such as- why their results are poor, why they are irregular in their study and many more. Even providing counseling, we can know their weakness, strength, and opportunities. Not only that, but it also helps to build a good relationship between teachers and students. Students can overcome their gap that exists between students and teachers, and that will ensure good bonding among them. So counseling is a must factor to develop a qualified student. Before taking any decision against any student, it2019;s important to learn their present condition through counseling. That2019;s why proper counseling with an effective way is necessary for all students. To understand the effects of counseling and academic advising, we surveyed on Daffodil International University. With this survey, we tried to realize all of the facts related to it. Based on the analysis, we have also mentioned some recommendations which may be helpful for the betterment of the undergraduate students

    Neonatal outcomes and congenital anomalies in pregnancies affected by hypothyroidism

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    Background: Maternal hypothyroidism has been reported to have concerns over neonatal outcomes, not only in the context of neurocognitive development but also in the short term as birth weight and neonatal jaundice.Patients and methods: We conducted a cross-sectional retrospective study on 638 cases who delivered live births in the Aga Khan University Hospital after ethical approval. Data were collected on hypothyroid pregnant females who were diagnosed before conception or during their antenatal visits during the year 2008-2016. Neonatal outcomes were noted for birth weight, maturity, and neonatal jaundice, neonatal hypothyroidism, neonatal respiratory distress syndrome, sepsis, hypocalcaemia, congenital anomalies, need for intensive care admission, and neonatal death. Subgroup analysis was performed on the timing of diagnosis of maternal hypothyroidism. Data analysis was performed on Statistical Package for the Social Sciences version 20.0.Results: Neonatal jaundice was the most common neonatal outcome (37.6%) in our cohort of 662 live births. Nearly 15% required intensive care unit admission, however, neonatal death was very rare. The most common clinically significant congenital anomalies were cardiovascular defects, whereas Mongolian spots were the commonest congenital condition to report. There is a statistically significant association between low birth weight (OR 1.86, 95% CI 1.0-3.2, p ≤ 0.05) and congenital anomalies (OR 2.39, 95% CI 1.4-4.0, p ≤ 0.05) with women diagnosed with hypothyroidism before pregnancy.Conclusion: We report the neonatal outcomes and spectrum of congenital anomalies of hypothyroid pregnancies diagnosed before and during conception for the first time from the region of Pakistan.Key Message: Overall, none of the neonates of hypothyroid pregnancies developed congenital hypothyroidism.Cardiovascular defects in these neonates imply extensive screening and monitoring during pregnancy.Low birth weight and congenital anomalies are associated with the timings of diagnosis of hypothyroidism in pregnancy

    Frequency and Causes of Pediatric Ovarian Torsion: A Systematic Review

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    Objective: The aim of my study was to determine the frequency and causes of pediatric ovarian torsion. Background: The condition in which an ovary twist along the ligament which hold it in place is known as Ovarian Torsion. The blood flow to ovary and fallopian tube could be cut off because of this twisting. ovarian torsion cab be a cause of unbearable pain due to lack of sufficient blood that should be received by ovary. On behalf of this systematic review, I wanted to dictate the frequency and causes of pediatric ovarian torsion. On the basis of past studies, I reviewed ovarian torsion can be happen at any paediatric age (infant to eighteen years). Around fifty-two % of the cases in children happen between nine years to fourteen years of age, with a median of age 11. Method: An electric database search was performed (google scholar, PubMed and science direct) with time limit until January 2020. All studies, fully available in English, assessing the frequency and causes of pediatric ovarian torsion. Study design: Systematic review-based design is used for this study. Results: 16 articles were reviewed, I found that frequency of pediatric ovarian torsion were rare and happened at any pediatric age. Ovarian torsion was caused by benign lesion, malignancy or by normal ovary. Purpose: The aim of my study was to determine the frequency and causes of pediatric ovarian torsion. Keywords: Ovarian torsion, oophorectomy, neoplasm, malignancy. DOI: 10.7176/JHMN/90-15 Publication date:June 30th 202

    Relationship of Type II Diabetes Mellitus in Women with Polycystic Ovarian Syndrome: A Systematic Review

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    Objective: The purpose of my study was to determine the relationship of Type 2  diabetes mellitus in women with PCOS. Background: PCOS is a hormonal disorder affecting millions of women around the world. 1 in every 10 women have PCOS but many women go years before receiving the diagnosis. In fact it is estimated that 70% of PCOS cases have a root cause is insulin resistance, A major risk factor for Type 2 diabetes mellitus. More than half of women with PCOS develop type 2 diabetes. PCOS is linked with higher levels of circulating insulin, which is characteristic in type 2 diabetes. IR is the typical condition of subjects with T2D. Women with PCOS share with people with T2D the same impaired glucose pattern consisting of a prevalent disturbance of fasting blood glucose. Higher levels of IR stress the pancreatic beta cell function, resulting in earlier functional depletion of insulin secretion capacity and higher risk of developing T2D. In this Systematic review I wanted to determine the incidence of type 2 diabetes in women with PCOS. According to the studies that I reviewed women with PCOS have a markedly increased risk of developing type 2 diabetes then women without PCOS and there is a higher prevalence of PCOS in those women who have Type 2 diabetes mellitus rather than non-diabetic. Method:An electric database search was performed (google scholar, PubMed and science direct)  without time limit until january 2020. All studies, fully available in English, assessing the incidence Type II Diabetes Mellitus in Women with PCOS.  Study design: Systematic review.  Results:I reviewed 22 articles and found that there were high risk of Diabetes Mellitus Type 2 in PCOS females then other one. Middle aged women with PCOS were having elevated risk of Type 2 Diabetes Mellitus, So therefore it propped up the needs of PCOS for routine screening of diabetes. The information or data from articles likewise gave furthur clinical bits of knowledge on the side of focusing on BMI (Body Mass Index), glucose (fasting glucose and after glucose ingestion) and in risk stratification and intervention for glucose homeostasis maintenance. Keywords: Polycystic Ovarian Disease, Type II Diabetes Mellitus, Insulin Resistance DOI: 10.7176/JHMN/90-13 Publication date:June 30th 202

    A survey of prescription pattern of anti-diabetic drugs on diabetic patients with cardiovascular complications within Dhaka metropolis

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    Background: This survey study was designed to analyze the current prescription pattern of anti-diabetic drugs that used in diabetic patients with cardiovascular complications within Dhaka metropolis.Methods: The present study has been conducted by out-patient department in a number of well-known general and specialized government and private hospitals in Dhaka, Bangladesh for 5 months. 1200 prescriptions and questionnaire were randomly evaluated for this present survey. A standard questionnaire was prepared, containing 17 different questions, to conduct the survey based on patient’s demographic data such as which type of diabetes they have contained, age, gender, education and their self-assessment of health, disease history and medication.Results: Among the patients involved in this study, there were 46% (550) male and 54% (650) female between the ages of 30 and 75 years. Between 46 and 70 years, 19% male and 31% female were found to be diabetic indicating that in this age group female are mostly affected by diabetes. About 2020 antidiabetic drugs were prescribed by the physicians in which 30.43% contained single, 54.16% contained two and 15% contained more than two anti-diabetic drugs. Amongst antidiabetic medications, metformin was the most commonly prescribed drug which was given in 30.69% patients followed by glimepride 10.9%, 5.45% had glipizide, 1% pioglitazone and other drugs. A total of 7.43% drug was prescribed by fixed dose combinations. Highest percentage of male diabetic patients with hypertension (86%), dyslipidemia (100%) and other complications (57%) was found at 75 years of age while no female patients were found under the same condition at the same age.Conclusions: The findings can serve as a guide to choose the formulation and combination of anti-diabetic drugs in this part of the world before developing & marketing any new drug. Therefore it is necessary to create better awareness among people, focus on rational use of anti-diabetic drugs and also motivate our physicians to prescribe the generic drugs

    Leptospirosis: Rising Nuisance for Cattle and Threat to Public Health

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    Leptospirosis is a communicable disease at farms that results in abortion and pathological changes in animals and human respectively. Disease is majorly spreading through indirect contact with contaminated urine material. The causative agent belongs to Leptospira genus having 21 species, 25 serogroups, and 250 serovars. The prevalence noted at world level is counted to be 41.39% with 30.11% in Asia, 25.62% in Africa, and 46.42% in South Africa. The virulence is attributed to Loa22 protein which is the first protein identified as essential virulence factor. Pathogenesis involves vasculitis following which are direct cytotoxicity and immunological injury resulting in renal failure. Direct examination, PCR, isothermal methods, microscopic agglutination test (MAT) and IgM enzyme-linked immunosorbent assay (ELISA) are diagnostic approaches for leptospirosis. The MAT is a gold standard test for leptospirosis identification. Doxycycline and azithromycin were used as drugs against leptospirosis in mild and severe cases of leptospirosis. Further studies are needed regarding identification, treatment, and effective vaccination

    Measuring Coverage in MNCH:A Prospective Validation Study in Pakistan and Bangladesh on Measuring Correct Treatment of Childhood Pneumonia

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    Antibiotic treatment for pneumonia as measured by Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS) is a key indicator for tracking progress in achieving Millennium Development Goal 4. Concerns about the validity of this indicator led us to perform an evaluation in urban and rural settings in Pakistan and Bangladesh.Caregivers of 950 children under 5 y with pneumonia and 980 with "no pneumonia" were identified in urban and rural settings and allocated for DHS/MICS questions 2 or 4 wk later. Study physicians assigned a diagnosis of pneumonia as reference standard; the predictive ability of DHS/MICS questions and additional measurement tools to identify pneumonia versus non-pneumonia cases was evaluated. Results at both sites showed suboptimal discriminative power, with no difference between 2- or 4-wk recall. Individual patterns of sensitivity and specificity varied substantially across study sites (sensitivity 66.9% and 45.5%, and specificity 68.8% and 69.5%, for DHS in Pakistan and Bangladesh, respectively). Prescribed antibiotics for pneumonia were correctly recalled by about two-thirds of caregivers using DHS questions, increasing to 72% and 82% in Pakistan and Bangladesh, respectively, using a drug chart and detailed enquiry.Monitoring antibiotic treatment of pneumonia is essential for national and global programs. Current (DHS/MICS questions) and proposed new (video and pneumonia score) methods of identifying pneumonia based on maternal recall discriminate poorly between pneumonia and children with cough. Furthermore, these methods have a low yield to identify children who have true pneumonia. Reported antibiotic treatment rates among these children are therefore not a valid proxy indicator of pneumonia treatment rates. These results have important implications for program monitoring and suggest that data in its current format from DHS/MICS surveys should not be used for the purpose of monitoring antibiotic treatment rates in children with pneumonia at the present time

    COVID-19 and the Global Impact on Colorectal Practice and Surgery

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    Background: The novel severe acute respiratory syndrome coronavirus 2 virus that emerged in December 2019 causing coronavirus disease 2019 (COVID-19) has led to the sudden national reorganization of health care systems and changes in the delivery of health care globally. The purpose of our study was to use a survey to assess the global effects of COVID-19 on colorectal practice and surgery. Materials and Methods: A panel of International Society of University Colon and Rectal Surgeons (ISUCRS) selected 22 questions, which were included in the questionnaire. The questionnaire was distributed electronically to ISUCRS fellows and other surgeons included in the ISUCRS database and was advertised on social media sites. The questionnaire remained open from April 16 to 28, 2020. Results: A total of 287 surgeons completed the survey. Of the 287 respondents, 90% were colorectal specialists or general surgeons with an interest in colorectal disease. COVID-19 had affected the practice of 96% of the surgeons, and 52% were now using telemedicine. Also, 66% reported that elective colorectal cancer surgery could proceed but with perioperative precautions. Of the 287 respondents, 19.5% reported that the use of personal protective equipment was the most important perioperative precaution. However, personal protective equipment was only provided by 9.1% of hospitals. In addition, 64% of surgeons were offering minimally invasive surgery. However, 44% reported that enough information was not available regarding the safety of the loss of intra-abdominal carbon dioxide gas during the COVID-19 pandemic. Finally, 61% of the surgeons were prepared to defer elective colorectal cancer surgery, with 29% willing to defer for ≤ 8 weeks. Conclusion: The results from our survey have demonstrated that, globally, COVID-19 has affected the ability of colorectal surgeons to offer care to their patients. We have also discussed suggestions for various practical adaptation strategies for use during the recovery period. We have presented the results of a survey used to assess the global impact of coronavirus disease 2019 (COVID-19) on the delivery of colorectal surgery. Despite accessible guidance information, our results have demonstrated that COVID-19 has significantly affected the ability of colorectal surgeons to offer care to patients. We have also discussed practical adaptation strategies for use during the recovery phase

    Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

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    Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack number. Participants, care givers, and those assessing outcomes were masked to allocation. We originally planned to enrol 15 000 women with a composite primary endpoint of death from all-causes or hysterectomy within 42 days of giving birth. However, during the trial it became apparent that the decision to conduct a hysterectomy was often made at the same time as randomisation. Although tranexamic acid could influence the risk of death in these cases, it could not affect the risk of hysterectomy. We therefore increased the sample size from 15 000 to 20 000 women in order to estimate the effect of tranexamic acid on the risk of death from post-partum haemorrhage. All analyses were done on an intention-to-treat basis. This trial is registered with ISRCTN76912190 (Dec 8, 2008); ClinicalTrials.gov, number NCT00872469; and PACTR201007000192283. Findings Between March, 2010, and April, 2016, 20 060 women were enrolled and randomly assigned to receive tranexamic acid (n=10 051) or placebo (n=10 009), of whom 10 036 and 9985, respectively, were included in the analysis. Death due to bleeding was significantly reduced in women given tranexamic acid (155 [1·5%] of 10 036 patients vs 191 [1·9%] of 9985 in the placebo group, risk ratio [RR] 0·81, 95% CI 0·65–1·00; p=0·045), especially in women given treatment within 3 h of giving birth (89 [1·2%] in the tranexamic acid group vs 127 [1·7%] in the placebo group, RR 0·69, 95% CI 0·52–0·91; p=0·008). All other causes of death did not differ significantly by group. Hysterectomy was not reduced with tranexamic acid (358 [3·6%] patients in the tranexamic acid group vs 351 [3·5%] in the placebo group, RR 1·02, 95% CI 0·88–1·07; p=0·84). The composite primary endpoint of death from all causes or hysterectomy was not reduced with tranexamic acid (534 [5·3%] deaths or hysterectomies in the tranexamic acid group vs 546 [5·5%] in the placebo group, RR 0·97, 95% CI 0·87-1·09; p=0·65). Adverse events (including thromboembolic events) did not differ significantly in the tranexamic acid versus placebo group. Interpretation Tranexamic acid reduces death due to bleeding in women with post-partum haemorrhage with no adverse effects. When used as a treatment for postpartum haemorrhage, tranexamic acid should be given as soon as possible after bleeding onset. Funding London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation
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