95 research outputs found

    The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019

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    PANDA Phase One - PANDA collaboration

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    The Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany, provides unique possibilities for a new generation of hadron-, nuclear- and atomic physics experiments. The future antiProton ANnihilations at DArmstadt (PANDA or P¯ANDA) experiment at FAIR will offer a broad physics programme, covering different aspects of the strong interaction. Understanding the latter in the non-perturbative regime remains one of the greatest challenges in contemporary physics. The antiproton–nucleon interaction studied with PANDA provides crucial tests in this area. Furthermore, the high-intensity, low-energy domain of PANDA allows for searches for physics beyond the Standard Model, e.g. through high precision symmetry tests. This paper takes into account a staged approach for the detector setup and for the delivered luminosity from the accelerator. The available detector setup at the time of the delivery of the first antiproton beams in the HESR storage ring is referred to as the Phase One setup. The physics programme that is achievable during Phase One is outlined in this paper

    Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

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    Background: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.Methods: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age.Findings: The number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran.Interpretation: Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings.Copyright (C) 2021 World Health Organization; licensee Elsevier.</p

    Solusi Fikih

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    Optimized Seizure Detection Algorithm: A Fast Approach for Onset of Epileptic in EEG Signals Using GT Discriminant Analysis and K-NN Classifier

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    Background: Epilepsy is a severe disorder of the central nervous system that predisposes the person to recurrent seizures. Fifty million people worldwide suffer from epilepsy; after Alzheimer’s and stroke, it is the third widespread nervous disorder. Objective: In this paper, an algorithm to detect the onset of epileptic seizures based on the analysis of brain electrical signals (EEG) has been proposed. 844 hours of EEG were recorded form 23 pediatric patients consecutively with 163 occurrences of seizures. Signals had been collected from Children’s Hospital Boston with a sampling frequency of 256 Hz through 18 channels in order to assess epilepsy surgery. By selecting effective features from seizure and non-seizure signals of each individual and putting them into two categories, the proposed algorithm detects the onset of seizures quickly and with high sensitivity. Method: In this algorithm, L-sec epochs of signals are displayed in form of a thirdorder tensor in spatial, spectral and temporal spaces by applying wavelet transform. Then, after applying general tensor discriminant analysis (GTDA) on tensors and calculating mapping matrix, feature vectors are extracted. GTDA increases the sensitivity of the algorithm by storing data without deleting them. Finally, K-Nearest neighbors (KNN) is used to classify the selected features. Results: The results of simulating algorithm on algorithm standard dataset shows that the algorithm is capable of detecting 98 percent of seizures with an average delay of 4.7 seconds and the average error rate detection of three errors in 24 hours. Conclusion: Today, the lack of an automated system to detect or predict the seizure onset is strongly felt

    Effect of sowing date and nitrogen fertilizer on sorghum (Sorghum bicolor L. var. Speed feed) forage production in a summer intercropping system

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    To evaluate the interaction effects of planting date and different levels of nitrogen fertilizer on sorghum (Sorghum bicolor var. Speed feed) forage production, an experiment was conducted in split plots based on a complete randomized block design in Agricultural Research Station of Khorramabad, Lorestan province, Iran. The experimental treatments comprised of three nitrogen fertilizer levels of control (N0), 100 (N1), and 150 kg per hectare (N2), assigned to main plots and three sowing dates of T1 (June, 10th), T2 (June 26th) and T3 (July 11th) assigned to subplots. Results showed that in sum of two harvests, the yield of hay, forage, leaf and shoot hay weigh in second planting date and N2 and N3 level of fertility was higher than all treatments. In the case of quality treatments the percent of crude protein in first harvest had the most amounts in first and second planting date and N1, N2 and N3 fertility levels. Crude fiber percentage in first harvest of second planting date was highest in N1, N2 and N3 levels of fertility. Treatment interactions had not any significant effect for crude fiber. The most ash percent was observed in first harvest and N1, N2 and N3 fertility level. In second harvest time N2 and N3 fertility levels were superior to the rest. Also, fat percentage in first and second planting date and N1, N2 and N3 increased than the control fertility treatment

    SUMMER INTERCROPPING SYSTEM IN FORAGE PRODUCTION EFFECT OF SOWING DATE AND NITROGEN FERTILIZER ON SORGHUM (SORGHUM BICOLOR L. VAR. SPEED FEED) FORAGE PRODUCTION IN A SUMMER INTERCROPPING SYSTEM

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    ABSTRACT. To evaluate the interaction effects of planting date and different levels of nitrogen fertilizer on sorghum (Sorghum bicolor var. Speed feed) forage production, an experiment was conducted in split plots based on a complete randomized block design in Agricultural Research Station of Khorramabad, Lorestan province, Iran. The experimental treatments comprised of three nitrogen fertilizer levels of control (N0), 100 (N1), and 150 kg per hectare (N2), assigned to main plots and three sowing dates of T1 (June, 10 th ), T2 (June 26 th ) and T3 (July 11 th ) assigned to subplots. Results showed that in sum of two harvests, the yield of hay, forage, leaf and shoot hay weigh in second planting date and N2 and N3 level of fertility was higher than all treatments. In the case of quality treatments the percent of crude protein in first harvest had the most amounts in first and second planting date and N1, N2 and N3 fertility levels. Crude fiber percentage in first harvest of second planting date was highest in N1, N2 and N3 levels of fertility. Treatment interactions had not any significant effect for crude fiber. The most ash percent was observed in first harvest and N1, N2 and N3 fertility level. In second harvest time N2 and N3 fertility levels were superior to the rest. Also, fat percentage in first and second planting date and N1, N2 and N3 increased than the control fertility treatment
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