158 research outputs found
Photometric Supernova Cosmology with BEAMS and SDSS-II
Supernova cosmology without spectroscopic confirmation is an exciting new
frontier which we address here with the Bayesian Estimation Applied to Multiple
Species (BEAMS) algorithm and the full three years of data from the Sloan
Digital Sky Survey II Supernova Survey (SDSS-II SN). BEAMS is a Bayesian
framework for using data from multiple species in statistical inference when
one has the probability that each data point belongs to a given species,
corresponding in this context to different types of supernovae with their
probabilities derived from their multi-band lightcurves. We run the BEAMS
algorithm on both Gaussian and more realistic SNANA simulations with of order
10^4 supernovae, testing the algorithm against various pitfalls one might
expect in the new and somewhat uncharted territory of photometric supernova
cosmology. We compare the performance of BEAMS to that of both mock
spectroscopic surveys and photometric samples which have been cut using typical
selection criteria. The latter typically are either biased due to contamination
or have significantly larger contours in the cosmological parameters due to
small data-sets. We then apply BEAMS to the 792 SDSS-II photometric supernovae
with host spectroscopic redshifts. In this case, BEAMS reduces the area of the
(\Omega_m,\Omega_\Lambda) contours by a factor of three relative to the case
where only spectroscopically confirmed data are used (297 supernovae). In the
case of flatness, the constraints obtained on the matter density applying BEAMS
to the photometric SDSS-II data are \Omega_m(BEAMS)=0.194\pm0.07. This
illustrates the potential power of BEAMS for future large photometric supernova
surveys such as LSST.Comment: 25 pages, 15 figures, submitted to Ap
Integrating Public Deliberation into Engineering Systems: Participatory Technology Assessment of NASA's Asteroid Redirect Mission
We discuss an experiment employing participatory technology assessment (pTA), a public deliberation method for eliciting lay citizen input prior to making decisions about science and technology, to inform upstream engineering decisions concerning technical aspects of NASA's Asteroid Initiative. In partnership with NASA, the Expert and Citizen Assessment of Science and Technology network conducted a pTA-based forum on NASA's Asteroid Initiative in late 2014. The goal of the exercise was to assess citizens' values and preferences about potential asteroid detection, asteroid mitigation, and exploration-based technologies associated with NASA's Initiative. This paper discusses the portion of the forum that focused on the Asteroid Redirect Mission, an effort to redirect an asteroid into lunar orbit that astronauts can study. The forum sought public input on two options for performing the mission that NASA included in technical assessments to make a down select decision: Option A (capturing a 10-meter-diameter asteroid) or Option B (redirecting a several-meter-diameter boulder from the surface of a larger asteroid). We describe the values and perceptions participants had about Option A and B, how these results were used by NASA managers, and the impact the results of the participatory technology assessment had on the down select
Clinical quality measures for intraoperative and perioperative management in carpal tunnel surgery
Open and Hidden Charm Production in 920 GeV Proton-Nucleus Collisions
The HERA-B collaboration has studied the production of charmonium and open
charm states in collisions of 920 GeV protons with wire targets of different
materials. The acceptance of the HERA-B spectrometer covers negative values of
xF up to xF=-0.3 and a broad range in transverse momentum from 0.0 to 4.8
GeV/c. The studies presented in this paper include J/psi differential
distributions and the suppression of J/psi production in nuclear media.
Furthermore, production cross sections and cross section ratios for open charm
mesons are discussed.Comment: 5 pages, 9 figures, to be published in the proceedings of the 6th
International Conference on Hyperons, Charm & Beauty Hadrons (BEACH04),
Chicago, IL, June 27 - July 3, 200
Search for the Flavor-Changing Neutral Current Decay with the HERA-B Detector
We report on a search for the flavor-changing neutral current decay using events recorded with a dimuon trigger in
interactions of 920 GeV protons with nuclei by the HERA-B experiment. We find
no evidence for such decays and set a 90% confidence level upper limit on the
branching fraction .Comment: 17 pages, 4 figures (of which 1 double), paper to be submitted to
Physics Letters
Measurement of the J/Psi Production Cross Section in 920 GeV/c Fixed-Target Proton-Nucleus Interactions
The mid-rapidity (dsigma_(pN)/dy at y=0) and total sigma_(pN) production
cross sections of J/Psi mesons are measured in proton-nucleus interactions.
Data collected by the HERA-B experiment in interactions of 920 GeV/c protons
with carbon, titanium and tungsten targets are used for this analysis. The
J/Psi mesons are reconstructed by their decay into lepton pairs. The total
production cross section obtained is sigma_(pN)(J/Psi) = 663 +- 74 +- 46
nb/nucleon. In addition, our result is compared with previous measurements
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
T cells rely for their development and function on the correct folding and turnover of proteins generated in response to a broad range of molecular cues. In the absence of the eukaryotic type II chaperonin complex, CCT, T cell activation induced changes in the proteome are compromised including the formation of nuclear actin filaments and the formation of a normal cell stress response. Consequently, thymocyte maturation and selection, and T cell homeostatic maintenance and receptor-mediated activation are severely impaired. In the absence of CCT-controlled protein folding, Th2 polarization diverges from normal differentiation with paradoxical continued IFN-γ expression. As a result, CCT-deficient T cells fail to generate an efficient immune protection against helminths as they are unable to sustain a coordinated recruitment of the innate and adaptive immune systems. These findings thus demonstrate that normal T cell biology is critically dependent on CCT-controlled proteostasis and that its absence is incompatible with protective immunity
- …