Designing a Tool to Assess Professional Competences: Theoretical Foundations and Potential Applications

This conceptual paper outlines the descriptive theoretical foundations or kernel theories for designing an information and communication technology (ICT) tool to assess professional competences in the Austrian trade and craft sector. Upon completion, the ICT-tool serves as a boundary object in which applicants and assessors can interact. While this paper consists of a literature review and conceptual discussion, the overall project is methodologically placed within a multidisciplinary design-science paradigm. Design science scaffolds and structures the development of a theoretical model, the generation of assessment-items and the ICT-tool itself. This paper discusses the necessary descriptive knowledge or kernel theories on which the design of the ICT-tool rests. First, we describe the validation of prior learning - a process advocated by the European Union to make professional competences visible. Second, we describe the process how professional competences come about: through formal, non-formal and informal learning. Subsequently, we outline a knowledge-driven discourse on professional competences and discuss how different definitions of professional competence afford different approaches for its assessment. By presenting a use-case, we outline how the ICT-tool may guide applicants and assessors through this process

Revealing the Purpose of a Stakeholder Organisation: The Case of a Public University Responding to the COVID-19 'Corona' Crisis

In early March 2020, Austria declared a state of emergency due to COVID-19. Social life was put on hold, public and private organisations were largely shut down, and universities had to adapt their operations. A group of WU academics investigate how one of Europe's biggest public universities in business and economics responded to the crisis and in the process rediscovered its core purpose

A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes

The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and reversibly blocks voltage-gated and calcium-activated K+ channels (KV and KCa, respectively), resulting in depolarization of the membrane potential. As a result, Ca2+ signaling and nuclear factor of activated T cells (NF-AT)-driven gene expression are inhibited. Progesterone acts distally to the initial steps of T cell receptor (TCR)-mediated signal transduction, since it blocks sustained Ca2+ signals after thapsigargin stimulation, as well as oscillatory Ca2+ signals, but not the Ca2+ transient after TCR stimulation. K+ channel blockade by progesterone is specific; other steroid hormones had little or no effect, although the progesterone antagonist RU 486 also blocked KV and KCa channels. Progesterone effectively blocked a broad spectrum of K+ channels, reducing both Kv1.3 and charybdotoxin-resistant components of KV current and KCa current in T cells, as well as blocking several cloned KV channels expressed in cell lines. Progesterone had little or no effect on a cloned voltage-gated Na+ channel, an inward rectifier K+ channel, or on lymphocyte Ca2+ and Cl- channels. We propose that direct inhibition of K+ channels in T cells by progesterone contributes to progesterone-induced immunosuppression

A Nongenomic Mechanism for Progesterone-mediated Immunosuppression: Inhibition of K+ Channels, Ca2+ Signaling, and Gene Expression in T Lymphocytes

The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and reversibly blocks voltage-gated and calcium-activated K+ channels (KV and KCa, respectively), resulting in depolarization of the membrane potential. As a result, Ca2+ signaling and nuclear factor of activated T cells (NF-AT)-driven gene expression are inhibited. Progesterone acts distally to the initial steps of T cell receptor (TCR)-mediated signal transduction, since it blocks sustained Ca2+ signals after thapsigargin stimulation, as well as oscillatory Ca2+ signals, but not the Ca2+ transient after TCR stimulation. K+ channel blockade by progesterone is specific; other steroid hormones had little or no effect, although the progesterone antagonist RU 486 also blocked KV and KCa channels. Progesterone effectively blocked a broad spectrum of K+ channels, reducing both Kv1.3 and charybdotoxin–resistant components of KV current and KCa current in T cells, as well as blocking several cloned KV channels expressed in cell lines. Progesterone had little or no effect on a cloned voltage-gated Na+ channel, an inward rectifier K+ channel, or on lymphocyte Ca2+ and Cl− channels. We propose that direct inhibition of K+ channels in T cells by progesterone contributes to progesterone-induced immunosuppression

Revealing the Purpose of a Stakeholder Organisation: The Case of a Public University Responding to the Covid-19 'Corona' Crisis: Responding to 'Corona' Crisis

In early March 2020, Austria declared a state of emergency due to COVID-19. Social life was put on hold, public and private organisations were largely shut down, and universities had to adapt their operations. A group of WU1 academics investigate how one of Europe’s biggest public universities in business and economics responded to the crisis and in the process rediscovered its core purpose

Reduced performance after return to competition in ACL injuries: an analysis on return to competition in the ‘ACL registry in German Football’

Purpose ACL injuries are one of the most severe injuries in football, but medical consequences and performance outcomes after return to competition are only rarely investigated. Aim of this study was to analyse the time of return to competition (RTC) in German professional, semi-professional and amateur football. Also, this investigation highlights the rate of career ending and performance outcome after RTC in different playing levels by the measurement of playing level, performed matches and played minutes. Methods Database of this investigation is the ‘ACL registry in German Football’ with prospectively collected injury data. Between 2014 and 2018, four seasons in professional (1st–3rd league), semi-professional (4th–6th league) and amateur leagues (7th league) were analysed regarding the return to competition period and performance parameters. Data were collected for three subsequent seasons after injury and compared with the pre-injury and injury season. Data collection was performed using standardized methods. Results A total of 607 ACL injuries were registered during the 4-year period with a mean RTC time of 337.1 day (SD: 183). After primary ACL ruptures, the fastest RTC was found in professional football (247.3 days), while in semi-professional (333.5 d; p < 0.0001) and amateur football (376.2 d; p < 0.0001) a prolonged absence was detected. Re-ruptures occurred in 17.8% (n = 108) and showed similar trend with fastest RTC in professionals (289.9 days; p = 0.002). Within the first three seasons after injury, 92 players (36.7%) in semi-professional and 24 (20%) in professionals had to end their career. Keeping the level of play was only possible for 48 (47.5%) of professionals, while only 47 (29.6%) of semi-professionals and 43 (28.1%) of amateurs were able to. Only in professional football, no significant difference could be seen in the played minutes and games after 2 years compared to the pre-injury season. Conclusion Lower playing levels and re-ruptures are the main factors for a prolonged return to competition after ACL rupture in German football. Significant reduction in playing level and a high rate of career endings were found for all levels of play. However, only professional players were able to regain their playing minutes and games 2 years after injury, while lower classed athletes did not reach the same amount within 3 years. Level of evidence Level III

Early functional rehabilitation after patellar dislocation—What procedures are daily routine in orthopedic surgery?

Introduction: Patellar dislocation and rupture of the medial patellofemoral ligament (MPFL) are frequently seen in daily orthopedic practice. Besides initial non-surgical treatment, surgery and subsequent rehabilitation are crucial for restoring stability in the femoropatellar joint. This study investigated current rehabilitation strategies after patellar dislocation because knowledge on this topic has been severely limited so far. Materials and methods: The current rehabilitation protocols of 42 orthopedic and trauma surgical institutions were analyzed regarding their recommendations on weight bearing, range of motion (ROM), and use of movement devices and orthosis. All protocols for conservative treatment and postoperative rehabilitation after MPFL reconstruction were compared. Descriptive and statistical analyses were carried out when appropriate. Results: The different rehabilitation strategies for conservative and surgical treatment after patellar dislocation showed a tendency towards earlier functional rehabilitation after surgical MPFL reconstruction than after conservative treatment. Both surgical and conservative treatment involved initial restrictions in weight bearing, ROM, and use of movement devices and orthosis at the beginning of rehabilitation. The rehab protocols showed a significant earlier full weight bearing after surgical MPFL reconstruction (p> 0.001). Due to the presence of other parameters for early functional treatment, the absence of an indication for using orthosis (surgical: 44%, conservative: 33%; p = 0.515) or start of unlimited ROM of the knee (surgical: 4.9 weeks, conservative: 5.7 weeks; p = 0.076) showed by trend an earlier functional strategy after MPFL reconstruction than after conservative therapy. Conclusions: Both conservative and surgical treatment after patellar dislocation showed restrictions in the early phase of the rehabilitation. Earlier functional therapy was more common after MPFL reconstruction than after conservative treatment. Further clinical and biomechanical studies on rehabilitation strategies after patellar dislocation are needed to improve patient care and individualized therapy. (C) 2018 Published by Elsevier Ltd

Mitigating Wake Turbulence Risk During Final Approach Via Plate Lines

To mitigate the risk of wake vortex encounters during final approach, so-called plate lines have been developed. Wake vortices generated by landing aircraft induce secondary vortices at the plates’ surfaces that approach the primary vortices and trigger premature wake vortex decay. Each plate line consists of several upright plates that are installed underneath the approach glide path. While the plate line extends perpendicular to the flight direction, its individual plates are oriented in parallel to the runway centerline. In order to obtain the approval of the authorities for the installation of the plate lines at runway 16 of Vienna International Airport, the plate design had to comply with airport requirements like obstacle clearance, stability, and frangibility. During a six-month campaign wake vortex behavior of about 9,500 landings with and without plates was measured simultaneously by three lidars complemented by a comprehensive suite of meteorological instrumentation. The analysis of over 1000 measured wake vortex evolutions indicates that the plate lines reduce the lifetime of long-lived vortices in a safety corridor along the final approach by 21% to 35% depending on the aircraft type. This corresponds to a reduction of vortex circulation by about 50% for the most relevant ICAO separation (Medium behind Heavy)

Mitigating Wake Turbulence Risk During Final Approach via Plate Lines

To mitigate the risk of wake vortex encounters during final approach, so-called plate lines have been developed. Wake vortices generated by landing aircraft induce secondary vortices at the plates’ surfaces that approach the primary vortices and trigger premature wake vortex decay. Each plate line consists of several upright plates being installed underneath the approach slope. While the plate line extends perpendicular to the flight direction, its individual plates are oriented in parallel to the runway centerline. To obtain the approval of the authorities for the installation of the plate lines at runway 16 of Vienna International Airport, the plate design had to comply with airport requirements like obstacle clearance, stability, and frangibility. During a six-month campaign, wake vortex behavior of about 9500 landings with and without plates was measured simultaneously by three lidars complemented by a comprehensive suite of meteorological instrumentation. The analysis of over 1000 measured wake vortex evolutions indicates that the plate lines reduce the lifetimes of the vortices in a safety corridor along the final approach by 22–37% depending on the aircraft type. This corresponds to a reduction of vortex circulation by about 50% for the most relevant International Civil Aviation Organization separation (Medium behind Heavy)