The Periglacial Landscape Of Utopia Planitia; Geologic Evidence For Recent Climate Change On Mars.

The northern plains of Utopia Planitia, Mars, hosts an abundance of potential periglacial landforms including scalloped depressions, gullies, and polygon networks. This research was undertaken to investigate the distribution and stratigraphy of scalloped depressions in Utopia Planitia and to reconstruct the past environment in which this periglacial landscape formed. To that end, a revised geologic map of the region has been produced. We define, for the first time, a new Periglacial Unit, the youngest geologic unit in Utopia Planitia. We have also developed a model for the formation and evolution of the periglacial landscape examined by assessing the use of scalloped depressions as indicators of climate change, and combining our geologic evidence with recent climate change model predictions. It is concluded that in the recent past Utopia Planitia has experienced an intensified regional climate and a dynamic, evolving landscape that has recorded the changing climate of Mars

Care of obese women during labour: The development of a midwifery intervention to promote normal birth

Normal birth, defined as birth without induction of labour, anaesthetic, instruments or caesarean section conveys significant maternal and neonatal benefits. Currently one-fifth of women in the United Kingdom are obese. There is increasing evidence of the detrimental effects obesity has on intrapartum outcomes. There is a lack of research on how to minimise the associated risks of obesity through non-medicalised interventions and how to support obese women to maximise their opportunity for normal birth. This thesis aims to provide evidence to address this gap and develop an evidence-based intervention to promote normal birth. Using a methodological approach aligned with pragmatism, this research was conducted in four parts and underpinned by the Medical Research Council framework for the development of complex interventions. Part one was a national survey involving 24 maternity units. Part two was a qualitative study of the experiences of 24 health professionals and part three involved 8 obese women. The final part was a multi-disciplinary workshop that used consensus decision-making to design the intervention. Collectively, the findings suggest that intrapartum care of obese women is medicalised. Health professionals face challenges when caring for obese women but many strive to optimise the potential for normal birth by challenging practice and utilising ‘interventions’ to promote normality. The findings also demonstrate that obese women have an intrinsic fear of pregnancy and birth, have a desire for normal birth and ‘obese pregnancy’ presents a window of opportunity for change. The intervention consists of three component parts; an educational aspect (e-learning package), a clinical aspect (intrapartum care pathway) and a leadership aspect (ward champions). Whilst acknowledging the importance of safety, increasing intervention during labour for obese women may further increase the risk of complications, with detrimental effects. Addressing intrapartum management of obese women through non-medicalised interventions is of paramount importance in order to promote normality, maximise the opportunity for normal birth and reduce the associated morbidities

Issue 1: “It’s Better Late Than Never”: A Community-Based HIV Research and Training Response to Supporting Mothers Living with HIV Who Have Child Welfare Involvement (Part I)

Grounded in community-based research (CBR) principles and an anti-oppression framework, the Positive Parenting Pilot Project (P4) aimed to develop, implement, and evaluate an HIV education and training module to enhance the provision of support for families affected by HIV and who are at risk of or already involved with child protection services. We set out to strengthen the ability of Children’s Aid Societies (CAS) in Ontario to provide anti-oppressive services to families affected by HIV from diverse communities by increasing the capacity of social workers who support these families. Applying the principles of CBR, we increased communication and forged new collaborative relationships within and between CAS agencies, the HIV service sector, parents living with HIV, and researchers in order to better address family needs at societal and structural levels. The goal of this project was to develop, provide, and evaluate a framework for an anti-oppressive education and training module related to the multiple layers of oppression that are experienced by families living with HIV including HIV-related stigma and discrimination, racism, sexism, violence and poverty. This paper presents the qualitative analysis of pre- and post- focus groups with CAS workers who participated in P4 and the emerging practice implications for working with families living with and affected by HIV

Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: phenotypic and genotypic analysis of isolates

BACKGROUND: Workers in clinical microbiology laboratories are exposed to a variety of pathogenic microorganisms. Salmonella species is among the most commonly reported bacterial causes of laboratory-acquired infections. We report on three cases of laboratory-acquired Salmonella enterica serotype Typhi (Salmonella Typhi) infection which occurred over the period 2012 to 2016 in South Africa. METHODS: Laboratory investigation included phenotypic and genotypic characterization of isolates. Phenotypic analysis included standard microbiological identification techniques, serotyping and antimicrobial susceptibility testing. Genotypic analysis included the molecular subtyping methodologies of pulsed-field gel electrophoresis analysis, multilocus sequence typing and whole-genome sequencing (WGS); with WGS data analysis including phylogenetic analysis based upon comparison of single nucleotide polymorphism profiles of isolates. RESULTS: All cases of laboratory-acquired infection were most likely the result of lapses in good laboratory practice and laboratory safety. The following critical issues were highlighted. There was misdiagnosis and misreporting of Salmonella Typhi as nontyphoidal Salmonella by a diagnostic laboratory, with associated public health implications. We highlight issues concerning the importance of accurate fluoroquinolone susceptibility testing and interpretation of results according to updated guidelines. We describe potential shortcomings of a single disk susceptibility screening test for fluoroquinolone susceptibility and suggest that confirmatory minimum inhibitory concentration testing should always be performed in cases of invasive Salmonella infections. These antimicrobial susceptibility testing issues resulted in inappropriate ciprofloxacin therapy which may have been responsible for failure in clearance of pathogen from patients. Salmonella Typhi capsular polysaccharide vaccine was not protective in one case, possibly secondarily to a faulty vaccine. CONCLUSIONS: Molecular subtyping of isolates proved effective to investigate the genetic relatedness of isolates. Molecular subtyping data interpreted together with epidemiological data allowed us to pinpoint the most likely sources for our cases of laboratory-acquired infection

Pre-Mission Input Requirements to Enable Successful Sample Collection by a Remote Field/EVA Team

We used a field excursion to the West Clearwater Lake Impact structure as an opportunity to test factors that contribute to the decisions a remote field team (for example, astronauts conducting extravehicular activities (EVA) on planetary surfaces) makes while collecting samples for return to Earth. We found that detailed background on the analytical purpose of the samples, provided to the field team, enables them to identify and collect samples that meet specific analytical objectives. However, such samples are not always identifiable during field reconnaissance activities, and may only be recognized after outcrop characterization and interpretation by crew and/or science team members. We therefore recommend that specific time be allocated in astronaut timeline planning to collect specialized samples, that this time follow human or robotic reconnaissance of the geologic setting, and that crew member training should include exposure to the laboratory techniques and analyses that will be used on the samples upon their return to terrestrial laboratories

Short-term losses and long-term gains: the non-native species Austrominius modestus in Lough Hyne Marine Nature Reserve

The non-native barnacle species Austrominius modestus was first recorded in Ireland, close to Lough Hyne marine nature reserve in 1957. This species was not recorded inside the Lough until 1980, but by 2001 was the dominant intertidal barnacle within the reserve. It has been suggested that increases in the abundance of this species at other locations in Europe may be linked to increasing sea surface temperatures, and that A. modestus is an “ecological sleeper”. Despite an overall trend for increasing sea surface temperatures, this long term warming is punctuated by extreme events such as severely cold winters. A. modestus is warm water adapted, and has been recorded to decrease in abundance following cold winters. The winters of 2009/2010 and 2010/2011 were amongst the coldest recorded in Ireland in past decades. In the present study, higher levels of mortality were recorded for A. modestus than native barnacle species in Lough Hyne following these cold winters. Additionally, this species was recorded at lower abundances at the majority of sites surveyed in Lough Hyne in 2011 compared with 2009. Despite this, A. modestus remains the dominant barnacle species in the Lough and monitoring the recruitment of intertidal barnacles within Lough Hyne during 2014e2015 revealed that A. modestus was the most abundant recruit at study sites, both in removal plots and in the pre-existing community. The year-round breeding of A. modestus in addition to the closed nature of the Lough promotes A. modestus within the reserve. Despite this, native barnacle species continue to persist in Lough Hyne, though generally at low abundances, with the exception of exposed locations such as the Rapids and Bullock Island where natives outnumber A. modestus. The future intertidal barnacle community within the Lough is likely to be dominated by A. modestus with Chthamalus montagui and C. stellatus being abundant at sites which are not suitable for A. modestus. While the consequences of this are unknown, it is possible that the presence of A. modestus may alter trophic interactions and energy flow within the reserve

Correspondence between neurophysiological and clinical measurements of chemotherapy-induced peripheral neuropathy: secondary analysis of data from the CI-PeriNoms study

Chemotherapy-induced peripheral neuropathy (CIPN) lacks standardized clinical measurement. The objective of the current secondary analysis was to examine data from the CIPN Outcomes Standardization (CI-PeriNomS) study for associations between clinical examinations and neurophysiological abnormalities. Logistic regression estimated the strength of associations of vibration, pin, and monofilament examinations with lower limb sensory and motor amplitudes. Examinations were classified as normal (0), moderately abnormal (1), or severely abnormal (2). Among 218 participants, those with class 1 upper extremity (UE) and classes 1 or 2 lower extremity (LE) monofilament abnormality were 2.79 (95% confidence interval [CI]: 1.28-6.07), 3.49 (95%CI: 1.61-7.55), and 4.42 (95%CI: 1.35-14.46) times more likely to have abnormal sural nerve amplitudes, respectively, compared to individuals with normal examinations. Likewise, those with class 2 UE and classes 1 or 2 LE vibration abnormality were 8.65 (95%CI: 1.81-41.42), 2.54 (95%CI: 1.19-5.41), and 7.47 (95%CI: 2.49-22.40) times more likely to have abnormal sural nerve amplitudes, respectively, compared to participants with normal examinations. Abnormalities in vibration and monofilament examinations are associated with abnormal sural nerve amplitudes and are useful in identifying CIPN

Ornamental plants: annual reports and research reviews

Ohio State University Extension Nursery, Landscape, and Turf Team Directory: 1998 / Jack Kerrigan -- Floriculture Industry Roundtable of Ohio: 1998 / Charles Behnke -- Ohio State University Extension Buckeye Yard and Garden Line / James A. Chatfield, Pamela J. Bennett, Joseph F. Boggs, Gary Y. Gao, Jane C. Martin, David J. Shetlar and Randall H. Zondag -- Environmental and cultural problems of ornamental plants in Ohio: 1997 / Pamela J. Bennett and Jane C. Martin -- Insect and mite activity noted in Ohio nurseries and landscapes: 1997 / Joseph F. Boggs, David J. Shetlar, Jane C. Martin, Pamela J. Bennett, James A. Chatfield, Gary Y. Gao and Chris Carlson -- Summary of ornamental diseases in Ohio: 1997 / James A. Chatfield, Nancy J. Taylor, Stephen N. Nameth, Chris Carlson, Joseph F. Boggs, Jane C. Martin, Dan Balser and David Madison -- Weed problems in Ohio landscapes and nurseries: 1997 / Gary Y. Gao, Joseph F. Boggs, Pamela J. Bennett, Jane C. Martin, Mary Ann Rose, Joseph W. Rimelspach, Randall H. Zondag and William E. Pound -- Wildlife problems in Ohio landscapes: 1997 / Gary Y. Gao, Joseph F. Boggs, Jane C. Martin, Charles T. Behnke and James A. Chatfield -- Summary of turf cultural and disease problems in 1997 / Gary Y. Gao, Joseph F. Boggs, Pamela J. Bennett, Jane C. Martin, Joseph W. Rimelspach and James A. Chatfield -- Master Gardeners serve Ohio / Marianne Riofrio -- The greening of Poland's nurseries / Kenneth D. Cochran and Wojtek Grabczewski -- The marketing potential of Ginkgo biloba in the United States / Kenneth D. Cochran -- Composts in the Landscape: Effects on Soil pH and plant growth / Mary Ann Rose and Hao Wang -- How to optimize disease control using composts / Harry A. J. Hoitink, Wei-Zheng Zhang, David Y. Han, Alexandra G. Stone, Matthew S. Krause and Warren A. Dick -- The flowering sequence of ornamental plants as a tool for predicting the phenology of insect pests / Daniel A. Herms -- Reducing maintenance costs may mean selecting plants with the fewest flaws / T. Davis Sydnor-- Comprehensive aesthetic evaluations of crabapples at Secrest Arboretum in Wooster: 1993-1997 / Erik A. Draper, James A. Chatfield, Kenneth D. Cochran, Peter W. Bristol and David E. Allen -- Precision control of microirrigation for container-grown mini-roses / Robert C. Hansen, Ted H. Short, C. C. Pasian and R. Peter Fynn -- Red thread (Laetisaria fuciformis) control study on perennial ryegrass / Joseph W. Rimelspach, Kerry Kline, Karl Danneberger and Michael Boehm-- Red thread (Laetisaria fuciformis) control study on Kentucky bluegrass / Joseph W. Rimelspach, Kerry Kline, Karl Danneberger and Michael Boehm -- Red thread - from novelty to nuisance / Joseph W. Rimelspach -- Chrysanthemum cultivars differ in response to photoperiod when grown under far-red absorbing filters / M. J. McMahon -- Improving fuchsia cutting performance by grafting / D. M. Napier and M. J. McMahon -- Paint/paclobutrazol mix on the inside surface of rooting wedge cells to control poinsettia cutting height / Claudio C. Pasian -- Response of poinsettias to paclobutrazol in paint applications / Claudio C. Pasian and Daniel K. Struve -- Dynamic transpiration of highly stressed container-grown Acer rubrum / Ted H. Short, Ahmet Irvem and Robert C. Hansen -- Effects of temperature on the development of Asiatic Lilies / J. Steininger and C. C. Pasian-- New publications for 1997-199

Risk factors for Coronavirus disease 2019 (Covid-19) death in a population cohort study from the Western Cape province, South Africa

Risk factors for coronavirus disease 2019 (COVID-19) death in sub-Saharan Africa and the effects of human immunodeficiency virus (HIV) and tuberculosis on COVID-19 outcomes are unknown. We conducted a population cohort study using linked data from adults attending public-sector health facilities in the Western Cape, South Africa. We used Cox proportional hazards models, adjusted for age, sex, location, and comorbidities, to examine the associations between HIV, tuberculosis, and COVID-19 death from 1 March to 9 June 2020 among (1) public-sector “active patients” (≥1 visit in the 3 years before March 2020); (2) laboratory-diagnosed COVID-19 cases; and (3) hospitalized COVID-19 cases. We calculated the standardized mortality ratio (SMR) for COVID-19, comparing adults living with and without HIV using modeled population estimates.Among 3 460 932 patients (16% living with HIV), 22 308 were diagnosed with COVID-19, of whom 625 died. COVID19 death was associated with male sex, increasing age, diabetes, hypertension, and chronic kidney disease. HIV was associated with COVID-19 mortality (adjusted hazard ratio [aHR], 2.14; 95% confidence interval [CI], 1.70–2.70), with similar risks across strata of viral loads and immunosuppression. Current and previous diagnoses of tuberculosis were associated with COVID-19 death (aHR, 2.70 [95% CI, 1.81–4.04] and 1.51 [95% CI, 1.18–1.93], respectively). The SMR for COVID-19 death associated with HIV was 2.39 (95% CI, 1.96–2.86); population attributable fraction 8.5% (95% CI, 6.1–11.1)